Standard name
Human Ortholog
Description Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.13 0 0.1 0 0 0 0 0 0
Bud Neck 0 0 0.12 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Cytoplasm 0.64 0.8 0.88 0.86 0.83 0.78 0.68 0.78 0.7 0.7 0.61 0.64 0.92 0.92 0.95 0.1 0 0.05 0.32 0.46 0.31 0.4 0.45 0.48
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.22 0.24 0.18 0.05 0 0.07 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.46 0.21 0 0.05 0 0.16 0.34 0.2 0.36 0.36 0.53 0.38 0 0 0 0.16 0.11 0.08 0.42 0.32 0.4 0.39 0.29 0.24
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.2 0.28 0.29 0 0 0 0 0 0
SpindlePole 0 0 0 0.05 0.08 0.05 0.07 0.07 0.05 0.05 0 0.07 0 0 0 0.28 0.37 0.22 0 0 0.05 0 0.08 0.08
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.18 0.14 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 2 2 0 1 0 0 0 0 1 1 2 7 0 4 0 2 6 5 4 6 14 12
Bud 3 2 5 3 6 3 6 8 9 11 14 10 5 2 0 12 3 10 1 2 1 1 4 11
Bud Neck 1 3 13 6 20 15 13 16 12 12 8 13 11 14 8 0 0 1 1 5 1 3 5 11
Bud Site 0 0 0 1 0 0 2 7 6 5 2 1 0 0 0 2 3 4 – – – – – –
Cell Periphery 0 1 1 1 3 0 0 1 1 2 2 1 1 4 0 2 2 7 0 0 1 3 6 6
Cytoplasm 90 138 99 158 269 234 252 323 307 230 181 188 328 394 503 9 3 5 50 90 42 104 211 221
Endoplasmic Reticulum 4 2 1 1 1 3 0 1 0 0 0 2 1 2 0 2 1 2 1 0 0 2 4 3
Endosome 0 0 0 0 3 3 0 0 1 0 0 1 2 2 7 20 19 19 7 7 9 10 11 12
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 2 2 2 0 1 0 1 2
Mitochondria 65 37 4 10 13 48 127 83 156 117 157 111 4 0 1 15 9 8 65 62 54 101 134 113
Nucleus 0 0 2 1 2 0 2 2 4 1 1 3 1 2 0 1 1 5 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 2
Nucleolus 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 1 4 0 0 0 0 2 0
Peroxisomes 0 0 0 1 2 0 0 0 1 0 0 1 0 1 1 19 22 30 1 1 2 0 5 3
SpindlePole 2 3 3 9 27 16 27 29 23 16 9 21 16 19 12 26 29 23 6 6 6 9 36 36
Vac/Vac Membrane 0 3 1 0 6 3 1 0 2 1 0 1 3 2 4 7 14 14 6 10 3 2 12 15
Unique Cell Count 141 173 112 184 324 299 372 416 436 328 296 294 356 430 528 93 79 103 157 197 136 260 468 465
Labelled Cell Count 167 191 131 193 352 326 430 470 522 396 377 354 375 449 536 122 109 136 157 197 136 260 468 465


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 2.8 3.8 4.4 4.2 4.4 3.5 3.2 3.5 2.9 3.1 2.8 3.2 4.7 4.8 4.9 6.4 6.8 6.7 4.6 5.0 5.0
Std Deviation (1e-4) 0.4 0.6 1.2 1.6 1.4 0.8 1.2 0.9 0.7 1.0 0.8 1.1 1.0 1.0 1.2 1.3 1.1 1.6 1.2 4.8 1.4
Intensity Change (Log2) – – – -0.06 -0.01 -0.34 -0.48 -0.33 -0.6 -0.51 -0.67 -0.44 0.1 0.12 0.16 0.53 0.63 0.61 0.05 0.18 0.19

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – 0 0
Bud Neck – – – – – – – – – – – – – 0 0
Bud Site – – – – – – – – – – – – – 0 0
Cell Periphery – – – – – – – – – – – – – 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – 0 0
Endosome – – – – – – – – – – – – – 0 0
Golgi – – – – – – – – – – – – – 0 0
Mitochondria – – – – – – – – – – – – – 0 0
Nuclear Periphery – – – – – – – – – – – – – 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – 0 0
Peroxisomes – – – – – – – – – – – – – 0 0
SpindlePole – – – – – – – – – – – – – 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – 0 0
Cytoplasm – – – – – – – – – – – – – 0 0
Nucleus – – – – – – – – – – – – – 0 0
Vacuole – – – – – – – – – – – – – 4.3 3.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -1.0796 -0.5165 -0.7898 -0.6759 -0.9989 -0.5823 0.0332 -0.105 -0.0916 -0.6501 -0.501 -0.5152 -1.1978 -0.8956 -1.0201 -1.215 -1.2648 -0.9317
Actin 0.0123 0.0106 0.0176 0.0029 0.0415 0.0107 0.0634 0.0077 0.0107 0.0027 0.0099 0.011 0.0123 0.0174 0.0073 0.0102 0.0154 0.0084
Bud 0.0008 0.0069 0.0025 0.002 0.0019 0.0016 0.003 0.0021 0.0074 0.0021 0.0033 0.0024 0.0043 0.0021 0.0072 0.0033 0.0027 0.0027
Bud Neck 0.0011 0.0022 0.0036 0.005 0.0028 0.0084 0.0067 0.003 0.006 0.0013 0.0008 0.0165 0.0018 0.0029 0.0028 0.0024 0.001 0.0086
Bud Periphery 0.0032 0.0083 0.0038 0.0052 0.0068 0.0022 0.0037 0.0049 0.0135 0.0084 0.0133 0.0047 0.0047 0.0039 0.0062 0.0083 0.0067 0.0027
Bud Site 0.0024 0.0384 0.0079 0.0054 0.0122 0.0009 0.015 0.0239 0.0118 0.0038 0.0036 0.0032 0.0068 0.0266 0.0123 0.0147 0.0017 0.0007
Cell Periphery 0.0011 0.0018 0.0011 0.0005 0.0007 0.0009 0.0028 0.0015 0.0021 0.0026 0.0006 0.0007 0.0012 0.0018 0.0035 0.0008 0.0005 0.0005
Cytoplasm 0.0231 0.0361 0.0441 0.0358 0.0168 0.0307 0.0317 0.0531 0.0407 0.0408 0.0292 0.0521 0.0353 0.047 0.0366 0.0302 0.0525 0.0488
Cytoplasmic Foci 0.1454 0.1434 0.1344 0.1212 0.1348 0.1315 0.1559 0.1629 0.1129 0.0859 0.1268 0.1401 0.1419 0.1453 0.1362 0.1163 0.1393 0.1455
Eisosomes 0.0013 0.0006 0.0006 0.0003 0.0011 0.0007 0.0017 0.001 0.001 0.001 0.0007 0.0004 0.0012 0.002 0.0017 0.0007 0.0004 0.0005
Endoplasmic Reticulum 0.0043 0.0018 0.0022 0.0044 0.0016 0.0016 0.004 0.0041 0.0033 0.0019 0.001 0.0016 0.0087 0.0045 0.0021 0.0027 0.0032 0.0033
Endosome 0.1301 0.115 0.1057 0.0341 0.075 0.0749 0.1336 0.0767 0.0815 0.048 0.0808 0.0771 0.1461 0.1356 0.1243 0.0765 0.2014 0.11
Golgi 0.0351 0.0505 0.0315 0.0339 0.0141 0.0354 0.0469 0.0402 0.0319 0.0311 0.0351 0.036 0.0619 0.0759 0.0477 0.0414 0.0742 0.0613
Lipid Particles 0.0489 0.0279 0.0526 0.0207 0.0531 0.0452 0.0779 0.0307 0.0304 0.0036 0.0491 0.0426 0.0669 0.0376 0.036 0.0309 0.0095 0.0352
Mitochondria 0.216 0.289 0.2908 0.4283 0.4191 0.3107 0.1208 0.2086 0.2952 0.2254 0.3205 0.2166 0.2673 0.2555 0.3036 0.3824 0.1998 0.3637
None 0.2743 0.1499 0.1856 0.2277 0.0818 0.195 0.2243 0.2664 0.2229 0.4529 0.2136 0.2653 0.1364 0.1455 0.1699 0.1281 0.1827 0.1063
Nuclear Periphery 0.0015 0.0008 0.0012 0.0024 0.0012 0.0025 0.0084 0.0022 0.0059 0.001 0.0007 0.0018 0.0048 0.0018 0.0014 0.0031 0.0014 0.0008
Nucleolus 0.0013 0.0023 0.0015 0.001 0.0029 0.0016 0.0047 0.0014 0.0022 0.0025 0.0009 0.0025 0.0042 0.0017 0.0024 0.0008 0.0005 0.0006
Nucleus 0.001 0.0024 0.0014 0.0015 0.0016 0.0016 0.0028 0.0013 0.0044 0.0035 0.001 0.0045 0.002 0.002 0.0019 0.0008 0.001 0.0009
Peroxisomes 0.0843 0.0961 0.0943 0.0569 0.1172 0.1278 0.0699 0.0957 0.0969 0.0723 0.0963 0.0983 0.0726 0.0766 0.081 0.1361 0.0873 0.0878
Punctate Nuclear 0.0017 0.0049 0.005 0.0023 0.0033 0.0083 0.0088 0.0028 0.0041 0.0031 0.0021 0.0095 0.0041 0.0023 0.0029 0.0024 0.0008 0.0026
Vacuole 0.0084 0.008 0.0091 0.0058 0.0069 0.0051 0.011 0.0077 0.0111 0.0044 0.0074 0.0092 0.0114 0.0094 0.0097 0.0042 0.0133 0.0054
Vacuole Periphery 0.0024 0.0029 0.0035 0.0027 0.0036 0.0026 0.0028 0.0021 0.0043 0.0016 0.0034 0.004 0.004 0.0026 0.0035 0.0034 0.0049 0.0034

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.5135 7.3532 17.9281 14.516 12.9502 12.9188 10.8867 18.6382 14.5935 14.4938
Translational Efficiency 1.4358 2.2295 0.8954 1.3591 1.3836 1.5858 2.1412 0.9493 1.3195 1.3624

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1297 505 2277 925 1244 1892 199 1502 2541 2397 2476 2427

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 625.12 725.01 814.35 753.01 623.86 711.67 873.60 794.06 624.50 714.48 819.11 778.41
Standard Deviation 67.16 92.40 89.44 103.98 69.83 86.44 95.06 107.27 68.49 87.90 91.34 107.89
Intensity Change Log 2 — 0.213868 0.381516 0.268536 — 0.189986 0.485751 0.348026 — 0.201988 0.434522 0.308788

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000344 0.001233 0.001330 0.001608 0.000250 0.000611 0.001120 0.000801 0.000298 0.000742 0.001313 0.001109
Bud Neck 0.049210 0.067691 0.031179 0.008219 0.039631 0.064547 0.005544 0.012418 0.044521 0.065209 0.029119 0.010818
Bud Site 0.009763 0.042053 0.024111 0.033364 0.007081 0.022699 0.010983 0.039878 0.008450 0.026777 0.023056 0.037395
Cell Periphery 0.000188 0.000334 0.000140 0.000221 0.000220 0.000216 0.000232 0.000220 0.000203 0.000241 0.000147 0.000221
Cytoplasm 0.234683 0.166273 0.393214 0.442009 0.258937 0.201147 0.316696 0.476768 0.246557 0.193800 0.387064 0.463521
Cytoplasmic Foci 0.370020 0.336590 0.061658 0.066463 0.358221 0.316222 0.099275 0.051404 0.364244 0.320513 0.064681 0.057143
Eisosomes 0.000311 0.000268 0.000056 0.000091 0.000280 0.000212 0.000135 0.000066 0.000296 0.000223 0.000062 0.000076
Endoplasmic Reticulum 0.000679 0.000503 0.003447 0.002320 0.001580 0.000661 0.004161 0.001822 0.001120 0.000628 0.003504 0.002012
Endosome 0.040707 0.063948 0.006981 0.011088 0.036662 0.061121 0.014939 0.006108 0.038727 0.061717 0.007621 0.008006
Golgi 0.018383 0.031001 0.001794 0.003742 0.018609 0.028361 0.003701 0.003116 0.018494 0.028917 0.001947 0.003354
Lipid Particles 0.021959 0.008614 0.002877 0.003439 0.030399 0.014585 0.007974 0.001839 0.026091 0.013327 0.003286 0.002449
Mitochondria 0.066955 0.060753 0.007184 0.005241 0.063380 0.083405 0.001657 0.001948 0.065205 0.078633 0.006739 0.003203
Mitotic Spindle 0.002897 0.008723 0.024065 0.016992 0.001753 0.012544 0.002601 0.018482 0.002337 0.011739 0.022340 0.017914
None 0.002310 0.001599 0.002606 0.004693 0.002393 0.003847 0.003554 0.003555 0.002351 0.003373 0.002682 0.003989
Nuclear Periphery 0.000412 0.000182 0.002575 0.001263 0.000979 0.000348 0.001573 0.001214 0.000690 0.000313 0.002494 0.001233
Nuclear Periphery Foci 0.000225 0.000275 0.000885 0.001202 0.000530 0.000298 0.002947 0.000889 0.000374 0.000293 0.001051 0.001009
Nucleolus 0.002654 0.002046 0.002117 0.001094 0.002152 0.002829 0.001844 0.000598 0.002408 0.002664 0.002095 0.000787
Nucleus 0.083449 0.054471 0.357954 0.240563 0.095360 0.063706 0.365770 0.262158 0.089280 0.061760 0.358582 0.253927
Peroxisomes 0.049073 0.099785 0.016141 0.011905 0.034130 0.055020 0.040271 0.007424 0.041758 0.064452 0.018080 0.009132
Vacuole 0.042358 0.049176 0.058808 0.142145 0.043298 0.061955 0.114409 0.107230 0.042818 0.059263 0.063277 0.120537
Vacuole Periphery 0.003419 0.004481 0.000878 0.002337 0.004155 0.005666 0.000615 0.002061 0.003779 0.005416 0.000857 0.002166

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.02 -6.16 -2.94 -0.03 0.25 -3.35 -2.50 -3.83 -0.50 1.12 -4.59 -6.82 -4.41 -0.95 2.04
Bud Neck -2.63 5.33 14.11 10.06 12.39 -6.35 12.60 10.25 17.00 -3.81 -6.22 6.08 16.82 20.27 10.64
Bud Site -6.33 -6.44 -4.29 3.16 -0.13 -10.17 -0.97 -7.66 -1.80 -4.94 -11.28 -7.41 -8.55 0.16 -1.77
Cell Periphery -2.60 2.65 0.54 2.77 -1.90 0.26 -0.74 2.04 1.64 2.35 -1.84 3.72 1.78 3.04 -1.89
Cytoplasm 5.84 -15.39 -13.63 -16.90 -1.64 6.50 -1.34 -15.30 -23.42 -6.64 7.73 -15.91 -21.12 -28.32 -4.83
Cytoplasmic Foci 2.75 44.82 43.76 25.52 1.17 4.87 24.60 45.36 47.25 5.21 6.52 58.04 63.86 53.33 4.92
Eisosomes 1.00 8.17 7.10 5.10 -6.51 4.49 7.29 15.70 15.58 6.34 3.76 13.43 12.64 14.18 -4.10
Endoplasmic Reticulum 1.84 -15.50 -11.03 -11.79 4.08 2.35 -5.40 -2.36 -12.48 4.68 2.47 -10.96 -6.97 -16.81 6.38
Endosome -4.27 14.27 13.15 11.43 -1.51 -7.39 7.36 13.98 22.90 5.07 -8.46 18.54 19.54 25.29 2.18
Golgi -3.34 11.58 9.70 8.31 -0.56 -4.32 8.56 10.61 15.61 0.84 -5.70 15.69 14.65 17.59 -0.38
Lipid Particles 6.68 13.25 12.91 3.87 -0.76 6.98 9.48 13.71 14.48 5.94 8.66 17.95 18.82 14.44 5.06
Mitochondria 0.93 13.36 13.86 8.55 2.76 -3.33 14.23 14.33 20.87 -0.04 -2.80 18.65 20.09 22.32 5.69
Mitotic Spindle -3.17 -9.15 -4.53 -1.59 3.20 -6.93 -1.15 -6.29 -1.06 -5.81 -7.24 -9.61 -7.62 -1.40 2.78
None 1.57 -0.90 -1.94 -2.81 -1.66 -1.70 -1.38 -1.95 0.76 0.10 -1.55 -1.20 -2.82 -0.03 -2.28
Nuclear Periphery 4.53 -13.99 -13.50 -16.32 5.73 2.23 -3.16 -2.89 -15.32 0.80 2.63 -10.33 -7.42 -20.99 6.10
Nuclear Periphery Foci -1.11 -9.58 -8.02 -6.49 -2.76 1.41 -3.40 -3.36 -8.58 2.95 0.62 -6.71 -8.28 -10.70 0.45
Nucleolus 0.40 0.37 3.25 2.16 5.25 -1.81 -0.65 4.87 6.24 2.25 -1.12 -0.14 5.45 6.40 6.73
Nucleus 3.65 -39.96 -19.47 -19.79 11.17 6.18 -13.04 -25.42 -31.93 3.83 6.93 -43.26 -32.64 -37.61 12.46
Peroxisomes -6.44 10.98 11.99 12.13 2.55 -6.05 0.30 11.03 18.44 2.97 -7.23 10.87 16.84 21.48 5.55
Vacuole -1.88 -8.75 -21.46 -18.55 -17.46 -5.57 -8.20 -22.03 -18.79 -1.10 -6.28 -11.80 -30.66 -26.11 -21.08
Vacuole Periphery -1.23 9.24 4.28 3.58 -1.36 -2.84 8.76 5.09 8.21 -1.41 -4.11 11.98 6.52 9.55 -1.49
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
Localization
Cell Percentages mitochondrion (28%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Ecm31

Ecm31


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ecm31-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available