Standard name
Human Ortholog
Description Glycosyltransferase involved in protein glycosylation; transfers GDP-mannose to methyl-alpha-mannoside in vitro; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.07 0.09 0.07 0.26 0.11 0.15 0.15 0.22 – 0.35 0.48 0.47 0.44 0.67 0.91 0.2 0.19 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0
Endosome 0.05 0 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.06
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.11 0.17 0.24 0 0.08 0.11 0.08 0 – 0.1 0.12 0.09 0 0 0 0.1 0.06 0.05 0 0 0 0 0 0
Nucleus 0.32 0.15 0.15 0.14 0.14 0.27 0.28 0.26 – 0.14 0.08 0.1 0.08 0 0 0.47 0.43 0.41 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.67 0.8 0.74 0.8 0.82 0.72 0.72 0.74 – 0.64 0.62 0.6 0.6 0.4 0.15 0.45 0.41 0.59 0.83 0.88 0.92 0.9 0.88 0.83
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud 0 0 0 1 0 1 0 0 – 2 2 2 1 0 0 0 0 0 0 1 2 2 2 4
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9 17 26 82 37 57 82 174 – 160 186 269 85 199 302 50 78 32 1 2 0 2 4 5
Endoplasmic Reticulum 0 1 0 0 0 2 1 3 – 0 2 0 1 3 2 11 25 17 0 0 0 0 2 2
Endosome 6 0 17 5 9 2 2 2 – 0 0 2 4 4 1 6 9 6 10 8 12 9 18 25
Golgi 0 1 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 1 0 1 1 0 2 2
Mitochondria 14 33 89 14 27 40 43 25 – 46 45 53 0 0 0 26 26 13 2 4 6 4 7 11
Nucleus 39 28 58 45 46 102 155 210 – 66 32 55 15 13 2 116 175 112 4 1 2 2 2 1
Nuclear Periphery 3 2 1 2 3 3 5 12 – 1 3 2 0 0 0 2 3 1 2 0 2 1 3 5
Nucleolus 1 1 1 3 0 0 0 2 – 2 0 1 0 0 0 1 1 0 0 0 1 1 1 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 2 0 0 0 0 – 0 0 0 0 0 0 1 2 0 0 0 1 0 1 2
Vac/Vac Membrane 82 152 278 249 269 270 395 587 – 295 238 340 116 117 50 111 167 163 129 171 375 248 380 330
Unique Cell Count 123 189 375 312 329 374 548 794 459 385 570 194 295 333 248 406 274 157 195 408 276 432 398
Labelled Cell Count 154 235 470 403 391 477 683 1015 572 509 724 223 337 357 324 487 345 157 195 408 276 432 398


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 5.8 5.2 5.9 6.9 6.7 6.5 6.7 – 5.9 5.9 6.1 6.2 5.9 5.9 5.6 6.7 8.1 6.9 7.1 7.2
Std Deviation (1e-4) 1.0 1.1 1.2 1.4 1.6 2.1 1.9 1.7 – 1.7 1.7 1.7 0.9 1.0 1.2 1.5 2.0 2.3 2.1 1.6 1.7
Intensity Change (Log2) – – – 0.17 0.4 0.35 0.32 0.35 – 0.18 0.18 0.21 0.24 0.17 0.17 0.11 0.36 0.63 0.4 0.43 0.46


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 6.9 2.0 3.6 3.7 6.3 – 9.6 12.7 13.1 10.5 16.5 22.3 4.9 5.0 2.1
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 4.9 4.9
Endosome -2.2 -1.3 -3.5 -4.4 -5.4 – -4.6 -4.2 -4.5 -1.5 -2.3 -3.6 -1.4 -1.8 -1.6
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria -7.0 -5.5 -4.7 -6.8 -11.1 – -5.3 -4.4 -6.1 -7.4 -9.0 -9.5 -4.2 -6.8 -6.6
Nucleus -0.4 -0.6 3.9 4.5 4.2 – -0.4 -3.1 -2.7 -2.6 -4.6 -7.1 8.5 8.4 7.3
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 1.8 2.4 -0.6 -0.7 -0.1 – -3.1 -3.6 -4.6 -3.5 -9.0 -15.7 -7.4 -9.3 -3.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0121 3.9476 3.1984 3.132 2.7937 3.4042 4.2604 6.2775 5.1629 5.0256 4.7281 5.6502 5.0015 7.4848 6.1941 6.305 5.3187 6.0723
Actin 0.0256 0.0003 0 0 0 0.0024 0.0099 0 0.0044 0 0.0195 0.0032 0.0037 0 0.002 0.0248 0 0
Bud 0.0006 0.0004 0.0003 0.0002 0.0002 0.0003 0.0002 0.0003 0.0007 0.0002 0.0003 0.0003 0.0006 0.0003 0.0005 0.0001 0.0002 0.0004
Bud Neck 0.0035 0.0009 0.0009 0.0005 0.0008 0.001 0.0007 0.0015 0.0039 0.0007 0.0011 0.0016 0.0025 0.0013 0.0029 0.0009 0.0011 0.0013
Bud Periphery 0.0017 0.0007 0.001 0.0004 0.0008 0.0011 0.0007 0.0007 0.0016 0.0005 0.0008 0.0011 0.0016 0.0008 0.0013 0.0003 0.0008 0.0014
Bud Site 0.0044 0.0018 0.0006 0.0003 0.0012 0.0005 0.0007 0.0013 0.0047 0.0007 0.0009 0.0008 0.0035 0.0009 0.0056 0.0006 0.0008 0.001
Cell Periphery 0.0035 0.0021 0.0028 0.0018 0.0033 0.0042 0.0025 0.0037 0.0029 0.001 0.0026 0.0039 0.003 0.0029 0.0031 0.0014 0.0018 0.0029
Cytoplasm 0.0152 0.0173 0.0063 0.0009 0.0007 0.0021 0.0049 0.0125 0.0056 0.0067 0.0019 0.0017 0.0028 0.0043 0.003 0.0013 0.0049 0.0013
Cytoplasmic Foci 0.0089 0.0057 0.0066 0.0024 0.0011 0.0049 0.0102 0.0041 0.0066 0.0045 0.0117 0.0028 0.0042 0.0046 0.0059 0.0071 0.006 0.0018
Eisosomes 0.0006 0 0 0 0 0 0.0001 0.0001 0.0001 0 0.0002 0 0.0001 0 0 0.0003 0 0
Endoplasmic Reticulum 0.0102 0.0018 0.0023 0.0005 0.0024 0.0018 0.0045 0.0033 0.0034 0.0016 0.0016 0.0018 0.0021 0.0032 0.0028 0.0005 0.0021 0.0015
Endosome 0.1456 0.0888 0.1986 0.1568 0.0886 0.1004 0.1735 0.1001 0.1441 0.1953 0.1653 0.1126 0.1456 0.1039 0.1431 0.1587 0.1847 0.1024
Golgi 0.0073 0.0019 0.004 0.0038 0.0019 0.0055 0.0077 0.004 0.009 0.0081 0.0084 0.004 0.0071 0.0047 0.0116 0.008 0.0042 0.0047
Lipid Particles 0.0261 0.0044 0.0066 0.0067 0.0138 0.021 0.0152 0.0076 0.0215 0.0077 0.0172 0.011 0.0249 0.01 0.0234 0.0059 0.0048 0.0172
Mitochondria 0.0362 0.013 0.0086 0.0019 0.0012 0.0161 0.0177 0.0041 0.0338 0.0326 0.0049 0.0056 0.0304 0.0026 0.0267 0.0014 0.0022 0.0091
None 0.0274 0.0026 0.0035 0.0001 0.0001 0.0006 0.0036 0.0065 0.0078 0.0067 0.001 0.0002 0.0014 0.0015 0.0005 0.0001 0.0004 0.0001
Nuclear Periphery 0.019 0.0064 0.0066 0.0011 0.0118 0.0168 0.006 0.0053 0.0124 0.0021 0.0027 0.0048 0.0056 0.0152 0.0106 0.0013 0.0053 0.0049
Nucleolus 0.0158 0.0038 0.0085 0.0035 0.0059 0.0031 0.0101 0.0039 0.0077 0.0024 0.003 0.0105 0.0129 0.0087 0.0066 0.0017 0.0023 0.0078
Nucleus 0.0338 0.0062 0.0042 0.0023 0.0044 0.005 0.0073 0.0046 0.0116 0.003 0.0023 0.0092 0.0082 0.0093 0.0146 0.0014 0.0099 0.0048
Peroxisomes 0.0027 0.0003 0.0006 0.0004 0.0005 0.0015 0.003 0.0006 0.0033 0.0006 0.0064 0.0012 0.002 0.0004 0.0018 0.0008 0.0002 0.0005
Punctate Nuclear 0.0097 0.0002 0.0001 0 0.0001 0.0027 0.0057 0.0001 0.0025 0.0001 0.0048 0.0002 0.0006 0.0002 0.0004 0.0001 0.0003 0.0001
Vacuole 0.4168 0.6571 0.5416 0.6535 0.704 0.6122 0.4864 0.6446 0.5002 0.5795 0.6074 0.6217 0.4982 0.621 0.5222 0.5885 0.6002 0.6053
Vacuole Periphery 0.1853 0.1842 0.1961 0.163 0.157 0.1968 0.2295 0.1911 0.2122 0.1458 0.1363 0.2017 0.2388 0.2042 0.2114 0.1951 0.1679 0.2314

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 56.1589 47.3743 55.6165 67.26 61.5317 45.8509 62.02 66.1063 74.933 67.6196
Translational Efficiency 1.0171 1.1003 0.8925 1.0151 0.81 1.5088 0.9639 0.9398 0.97 0.8688

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
79 1251 521 1453 2244 1556 2019 2159 2323 2807 2540 3612

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 965.66 780.77 842.07 892.55 778.30 770.37 878.00 891.74 784.67 775.00 870.63 892.07
Standard Deviation 114.57 130.10 91.69 135.49 109.67 97.90 104.09 121.83 114.97 113.50 102.70 127.50
Intensity Change Log 2 — -0.306618 -0.197575 -0.113582 — -0.014775 0.173895 0.196297 — -0.169038 -0.019900 0.032983

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000537 0.000400 0.000093 0.000692 0.000542 0.000043 0.000080 0.000331 0.000542 0.000202 0.000083 0.000476
Bud Neck 0.008854 0.018103 0.028087 0.016332 0.007084 0.012896 0.027370 0.020651 0.007144 0.015216 0.027517 0.018913
Bud Site 0.017017 0.014312 0.005644 0.029972 0.006925 0.007491 0.012301 0.026061 0.007268 0.010531 0.010936 0.027634
Cell Periphery 0.001922 0.000228 0.000255 0.000092 0.001750 0.000397 0.000034 0.000088 0.001756 0.000322 0.000079 0.000089
Cytoplasm 0.044996 0.108302* 0.164154* 0.101750* 0.009935 0.021825 0.091240 0.107244* 0.011127 0.060366 0.106196* 0.105034*
Cytoplasmic Foci 0.026045 0.030790 0.042329 0.081572 0.005635 0.011759 0.057122 0.057424 0.006329 0.020241 0.054088 0.067138
Eisosomes 0.000033 0.000022 0.000127 0.000023 0.000010 0.000018 0.000017 0.000018 0.000011 0.000020 0.000040 0.000020
Endoplasmic Reticulum 0.003543 0.001373 0.002919 0.001210 0.003044 0.002001 0.001390 0.001106 0.003061 0.001721 0.001704 0.001148
Endosome 0.109377 0.065546 0.071396 0.190479 0.036028 0.075281 0.237083* 0.198794 0.038523 0.070942 0.203098* 0.195449
Golgi 0.007748 0.001098 0.000574 0.005241 0.001340 0.001202 0.001611 0.003409 0.001558 0.001156 0.001399 0.004146
Lipid Particles 0.002869 0.001305 0.005806 0.004002 0.005115 0.001986 0.003090 0.003005 0.005038 0.001682 0.003647 0.003406
Mitochondria 0.001879 0.000789 0.000667 0.002726 0.001345 0.006168 0.001351 0.002038 0.001363 0.003771 0.001211 0.002315
Mitotic Spindle 0.001412 0.001885 0.001972 0.016454 0.000115 0.000268 0.005644 0.010260 0.000159 0.000989 0.004891 0.012751
None 0.000148 0.002293 0.003084 0.000236 0.000194 0.000222 0.000199 0.000467 0.000192 0.001145 0.000791 0.000374
Nuclear Periphery 0.001545 0.000327 0.003595 0.000605 0.000144 0.000391 0.001344 0.001142 0.000192 0.000363 0.001805 0.000926
Nuclear Periphery Foci 0.000564 0.000349 0.002991 0.002140 0.000082 0.000118 0.002550 0.001232 0.000098 0.000221 0.002640 0.001597
Nucleolus 0.004467 0.001869 0.010981 0.001123 0.000271 0.001168 0.004270 0.002366 0.000414 0.001481 0.005647 0.001866
Nucleus 0.048174 0.020365 0.369665* 0.006920 0.001226 0.006980 0.022348 0.013033 0.002823 0.012945 0.093589 0.010574
Peroxisomes 0.004831 0.001496 0.004430 0.011804 0.002113 0.001256 0.005855 0.006681 0.002205 0.001363 0.005563 0.008742
Vacuole 0.671211* 0.708935* 0.279181* 0.516930* 0.892496* 0.815599* 0.518652* 0.533386* 0.884971* 0.768062* 0.469533* 0.526766*
Vacuole Periphery 0.042827 0.020213 0.002048 0.009697 0.024607 0.032931 0.006447 0.011267 0.025226 0.027263 0.005545 0.010635

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.31 1.47 -0.34 -0.65 -3.38 2.00 1.83 0.90 -2.73 -2.33 1.19 1.84 0.40 -1.40 -4.21
Bud Neck -2.70 -4.65 -2.52 0.57 3.59 -4.89 -13.98 -12.23 -6.07 4.29 -7.45 -14.91 -13.04 -3.94 6.22
Bud Site 0.52 1.47 -1.54 -6.35 -9.53 -0.42 -4.34 -9.72 -9.07 -7.14 -2.79 -3.45 -12.62 -10.81 -10.90
Cell Periphery 0.96 0.98 1.04 3.25 2.39 8.92 11.48 11.11 10.36 -2.80 9.12 10.82 10.72 9.25 -1.00
Cytoplasm -3.75 -7.20 -4.07 -0.63 6.42 -4.84 -23.87 -24.75 -20.71 -1.72 -16.17 -28.88 -30.93 -13.21 1.16
Cytoplasmic Foci -0.72 -1.82 -7.09 -13.61 -9.86 -4.69 -25.97 -25.62 -21.04 0.06 -11.12 -27.21 -33.43 -23.43 -5.23
Eisosomes 1.70 -4.76 1.71 0.00 6.16 -4.59 -5.54 -5.27 -0.01 -0.04 -5.63 -8.00 -6.05 0.14 5.36
Endoplasmic Reticulum 3.01 -0.11 3.21 0.93 8.23 3.87 6.58 8.07 5.29 2.91 5.66 4.95 8.25 4.70 6.32
Endosome 1.88 2.03 -2.48 -16.18 -13.26 -9.89 -29.35* -27.77 -17.86 3.50 -10.18 -27.04 -32.56 -24.19 0.17
Golgi 1.27 1.39 0.63 -3.94 -4.92 0.39 -0.03 -3.32 -3.42 -3.34 1.19 1.20 -4.01 -5.23 -5.35
Lipid Particles 1.59 -1.74 -1.20 -7.20 1.05 2.35 1.29 1.38 -2.87 0.29 2.67 1.01 1.03 -6.49 0.05
Mitochondria 0.83 0.88 -0.31 -2.29 -2.42 -3.47 0.09 -1.56 3.07 -2.18 -2.91 0.46 -1.70 2.01 -2.71
Mitotic Spindle -0.32 -1.96 -6.46 -6.27 -5.40 -1.28 -6.91 -8.74 -8.63 -3.45 -2.12 -7.60 -11.25 -10.24 -5.67
None -2.44 -4.24 -0.82 2.35 4.12 -0.30 -0.89 -1.97 -1.85 -1.71 -2.41 -4.04 -1.82 1.91 2.71
Nuclear Periphery 2.85 -5.09 1.74 -3.33 8.36 -2.42 -11.96 -8.19 -6.31 2.29 -2.06 -14.77 -8.66 -7.17 7.34
Nuclear Periphery Foci 1.74 -5.25 -4.28 -5.05 3.46 -1.68 -6.39 -7.59 -7.42 2.94 -4.84 -8.39 -9.16 -8.44 3.89
Nucleolus 1.09 -2.46 1.28 1.42 6.02 -2.62 -10.39 -8.52 -3.92 3.74 -4.42 -11.49 -8.32 -2.84 7.50
Nucleus 1.89 -13.59 2.69 5.81 23.82 -5.80 -17.57 -14.70 -6.26 6.99 -8.87 -22.39 -11.46 0.27 19.70
Peroxisomes 1.58 0.53 -2.42 -8.17 -5.07 1.34 -4.80 -5.47 -8.45 -1.47 1.41 -4.37 -7.57 -11.68 -4.59
Vacuole -1.04 9.30 3.79 15.78 -14.98 10.42 49.08* 46.26* 32.14* -1.36 17.78 56.02* 53.24* 33.34 -6.81
Vacuole Periphery 1.82 3.33 2.78 7.30 -7.63 -4.09 16.34 11.32 12.86 -7.18 -1.14 17.11 12.45 14.60 -8.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glycosyltransferase involved in protein glycosylation; transfers GDP-mannose to methyl-alpha-mannoside in vitro; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain
Localization
Cell Percentages vacuole (86%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ktr4

Ktr4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ktr4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available