Standard name
Human Ortholog
Description Putative alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; relocalizes from nucleus to vacuole upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.36 0.61 0.69 0.8 0.76 0.78 0.79 0.72 0.79 0.75 0.77 0.79 0.87 0.96 0.97 0.29 0.22 0.21 0 0.08 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0
Endosome 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0.05 0 0 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0.09 0.07 0.05 0.11 0.13 0.17 0.18 0.12 0.23 0.2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.35 0.25 0.25 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.7 0.49 0.42 0.32 0.33 0.28 0.19 0.18 0.23 0.26 0.22 0.18 0.19 0.05 0 0.61 0.69 0.67 0.85 0.81 0.84 0.84 0.85 0.83
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1 1 0 0 0
Bud 0 1 1 0 3 15 11 9 13 18 23 29 0 0 2 0 0 0 1 2 1 2 1 3
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 1 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 3 1 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 224 289 343 316 529 639 788 682 700 792 679 895 286 235 331 83 72 47 8 41 23 13 5 8
Endoplasmic Reticulum 4 0 1 1 1 2 1 0 0 1 1 3 1 2 1 8 16 13 2 3 3 2 4 3
Endosome 43 13 16 4 25 4 6 11 4 17 4 7 7 0 3 4 11 8 45 26 25 12 5 20
Golgi 2 1 1 0 0 0 0 0 0 0 0 0 0 0 1 2 3 5 7 3 1 1 0 0
Mitochondria 30 10 47 26 35 92 133 163 160 122 199 227 0 0 0 7 4 4 20 6 16 12 8 13
Nucleus 45 4 6 4 6 15 21 34 18 16 10 15 2 1 0 100 82 56 1 1 1 1 1 2
Nuclear Periphery 0 2 1 3 7 1 12 15 6 6 3 2 0 0 0 0 1 0 3 1 1 1 2 4
Nucleolus 0 0 0 0 1 0 1 7 2 0 1 0 0 0 0 0 1 0 0 0 0 0 2 0
Peroxisomes 0 0 0 0 4 0 0 0 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 2 0 2 1 2 1 1 3 0 0 1 1 1 2 4 1 0 1 0 1
Vac/Vac Membrane 433 232 207 127 229 227 189 172 201 275 195 203 61 13 14 173 225 152 582 418 447 272 216 309
Unique Cell Count 615 475 497 396 700 821 1001 941 888 1059 882 1139 328 246 343 282 327 227 683 514 531 323 253 373
Labelled Cell Count 781 552 623 481 842 995 1164 1095 1107 1250 1121 1387 357 252 355 378 418 287 683 514 531 323 253 373


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.7 5.3 4.3 4.4 4.9 4.7 4.1 4.2 4.1 4.2 4.1 4.2 6.0 5.6 5.6 7.7 7.6 7.8 6.8 7.1 7.0
Std Deviation (1e-4) 0.8 0.9 0.8 1.3 1.3 1.3 1.0 1.1 1.2 1.0 0.9 1.0 0.9 1.2 1.2 1.7 1.8 1.9 1.3 1.3 1.4
Intensity Change (Log2) – – – 0.04 0.18 0.14 -0.05 -0.03 -0.05 -0.03 -0.08 -0.04 0.48 0.39 0.38 0.85 0.83 0.87 0.66 0.73 0.71


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.6 2.5 3.6 4.1 1.4 4.1 2.4 3.2 4.1 6.0 8.2 9.8 -10.7 -13.2 -12.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 4.6 0
Endosome 0 0 0 0 0 0 0 0 0 -0.9 -2.8 -2.2 -1.5 0.1 0.2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -5.7 -5.0 -5.9 -3.7 -4.8 -3.8
Nucleus 0 0 0.9 1.2 2.6 1.1 0.5 -0.1 0.2 0 0 0 13.4 10.9 10.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -2.9 -3.2 -5.2 -9.4 -9.6 -7.4 -6.2 -7.7 -10.2 -6.9 -10.2 -12.2 5.3 7.6 6.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2434 2.3355 1.9008 1.7956 1.4193 2.1722 3.638 5.4628 4.5018 4.5626 4.1912 4.95 1.7904 3.3621 2.7801 3.0979 3.1888 2.8528
Actin 0.0098 0.0001 0.0027 0.0064 0 0 0.0044 0 0 0 0 0 0.0004 0 0.0001 0 0 0
Bud 0.0018 0.0029 0.0053 0.0026 0.0009 0.0008 0.0005 0.0004 0.0009 0.0004 0.0006 0.0005 0.0002 0.0003 0.0003 0.0003 0.0005 0.0003
Bud Neck 0.0016 0.0013 0.0018 0.0013 0.0017 0.0028 0.0013 0.0014 0.001 0.0028 0.0018 0.0016 0.0005 0.0025 0.003 0.001 0.0023 0.0015
Bud Periphery 0.0017 0.0034 0.0044 0.0034 0.005 0.002 0.0012 0.001 0.0021 0.001 0.0017 0.0015 0.0006 0.0007 0.0009 0.0005 0.0013 0.0009
Bud Site 0.0047 0.0042 0.0098 0.0143 0.0011 0.0016 0.0012 0.0011 0.0019 0.002 0.0031 0.0008 0.0004 0.0011 0.0012 0.0019 0.0019 0.0006
Cell Periphery 0.0013 0.0015 0.001 0.0008 0.0032 0.0017 0.0015 0.0015 0.0015 0.0023 0.0015 0.0015 0.001 0.0021 0.0015 0.0005 0.0015 0.0022
Cytoplasm 0.033 0.0266 0.0211 0.008 0.0037 0.0138 0.0206 0.0118 0.0128 0.0038 0.0072 0.0093 0.0132 0.0269 0.0107 0.0064 0.0049 0.009
Cytoplasmic Foci 0.0347 0.0145 0.035 0.0301 0.0048 0.0132 0.016 0.0058 0.0122 0.0085 0.0049 0.0068 0.009 0.0111 0.0101 0.0065 0.0025 0.0053
Eisosomes 0.0001 0 0.0001 0 0 0 0.0002 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0063 0.0053 0.0042 0.0013 0.0012 0.0033 0.0064 0.0039 0.0048 0.002 0.0026 0.0042 0.0097 0.0085 0.0097 0.0012 0.0016 0.0043
Endosome 0.3971 0.2619 0.3859 0.2734 0.2318 0.1841 0.3499 0.206 0.2777 0.2903 0.1574 0.2316 0.3305 0.1859 0.249 0.2215 0.1103 0.168
Golgi 0.0229 0.0048 0.02 0.0073 0.0029 0.0047 0.0096 0.0054 0.0088 0.0063 0.0026 0.0069 0.0067 0.0028 0.0073 0.0018 0.0007 0.0031
Lipid Particles 0.0239 0.0052 0.019 0.0056 0.002 0.006 0.011 0.0033 0.0039 0.007 0.0023 0.0055 0.0062 0.0047 0.0057 0.0012 0.001 0.0089
Mitochondria 0.0285 0.006 0.0309 0.0144 0.0772 0.0077 0.0146 0.0043 0.0183 0.0027 0.0022 0.0079 0.0119 0.0021 0.0102 0.0003 0.0007 0.0089
None 0.0204 0.0011 0.0052 0.0014 0.001 0.0008 0.0121 0.0104 0.0031 0.0004 0.0005 0.0026 0.019 0.0091 0.0057 0.0002 0.0003 0.0019
Nuclear Periphery 0.0103 0.0106 0.0073 0.0026 0.0027 0.0073 0.0105 0.0041 0.0063 0.0027 0.0039 0.006 0.0187 0.0109 0.0114 0.003 0.0029 0.0065
Nucleolus 0.0037 0.0029 0.0067 0.0052 0.0021 0.0028 0.0011 0.0011 0.0016 0.0019 0.0014 0.0015 0.0012 0.0018 0.0022 0.0025 0.0026 0.0019
Nucleus 0.0076 0.0082 0.0076 0.0069 0.0039 0.006 0.0031 0.003 0.005 0.0019 0.0035 0.0045 0.006 0.0045 0.004 0.0025 0.0041 0.0053
Peroxisomes 0.0078 0.0006 0.0045 0.0321 0.0006 0.0006 0.0015 0.0003 0.0006 0.001 0.0003 0.0005 0.0004 0.0003 0.0007 0.0002 0.0001 0.0003
Punctate Nuclear 0.0047 0.0016 0.0018 0.0006 0.0001 0.0008 0.0008 0.0001 0.0006 0.0001 0.0001 0.0005 0.0005 0.0002 0.0002 0.0001 0.0001 0.0001
Vacuole 0.309 0.5548 0.3402 0.5248 0.5806 0.6373 0.4373 0.6415 0.5244 0.5913 0.6899 0.5854 0.4462 0.6205 0.542 0.6287 0.7739 0.6438
Vacuole Periphery 0.069 0.0825 0.0855 0.0575 0.0735 0.1025 0.0951 0.0936 0.1124 0.0716 0.1126 0.1207 0.1176 0.104 0.1241 0.1195 0.0868 0.127

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 80.3714 82.8069 59.639 72.0027 77.7123 94.3955 83.726 73.4068 79.0936 88.0179
Translational Efficiency 1.3907 1.0955 1.2275 0.9448 1.0938 0.9855 0.9755 1.1766 0.9116 1.0094

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2827 1198 205 1266 1792 1402 2911 1454 4619 2600 3116 2720

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 729.40 759.88 865.41 910.98 696.60 756.14 914.29 896.88 716.67 757.86 911.07 903.44
Standard Deviation 84.54 127.97 97.19 128.12 83.66 126.38 111.85 118.28 85.70 127.13 111.60 123.16
Intensity Change Log 2 — 0.059061 0.246674 0.320709 — 0.118323 0.392321 0.364584 — 0.088315 0.319660 0.342309

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000111 0.000060 0.001547 0.004378 0.000114 0.000137 0.000913 0.003182 0.000112 0.000101 0.000955 0.003738
Bud Neck 0.016092 0.011333 0.014375 0.017040 0.013483 0.012616 0.015510 0.018687 0.015080 0.012025 0.015436 0.017920
Bud Site 0.011121 0.011506 0.016620 0.067829 0.008646 0.010960 0.019595 0.037400 0.010161 0.011211 0.019400 0.051562
Cell Periphery 0.000075 0.000126 0.000181 0.000110 0.000078 0.000361 0.000035 0.000070 0.000076 0.000253 0.000044 0.000089
Cytoplasm 0.095338 0.080184 0.133495* 0.261835* 0.074158 0.041663 0.114358* 0.249745* 0.087121 0.059412 0.115617* 0.255372*
Cytoplasmic Foci 0.201176* 0.066273 0.188112* 0.109753 0.167960 0.050405 0.170208 0.145745 0.188289* 0.057716 0.171386 0.128993
Eisosomes 0.000069 0.000026 0.000116 0.000041 0.000055 0.000048 0.000019 0.000041 0.000063 0.000038 0.000025 0.000041
Endoplasmic Reticulum 0.002272 0.002773 0.008274 0.001520 0.001294 0.002761 0.001150 0.001052 0.001892 0.002766 0.001618 0.001270
Endosome 0.245482* 0.118103 0.164394 0.084760 0.205652* 0.140334 0.203106* 0.129863 0.230029* 0.130090 0.200559* 0.108870
Golgi 0.026102 0.003087 0.006252 0.009977 0.024825 0.006745 0.018547 0.008736 0.025606 0.005060 0.017738 0.009314
Lipid Particles 0.011763 0.004921 0.026449 0.004788 0.008810 0.003811 0.008737 0.004492 0.010617 0.004323 0.009902 0.004630
Mitochondria 0.014569 0.003150 0.001120 0.002824 0.012011 0.003991 0.008212 0.004607 0.013576 0.003603 0.007745 0.003778
Mitotic Spindle 0.002944 0.001221 0.046151 0.079770 0.002430 0.001582 0.063335 0.043978 0.002744 0.001416 0.062205 0.060637
None 0.000283 0.000898 0.001975 0.000731 0.000394 0.000345 0.000249 0.000808 0.000326 0.000599 0.000362 0.000772
Nuclear Periphery 0.000182 0.000499 0.004138 0.001008 0.000278 0.000193 0.001763 0.001264 0.000219 0.000334 0.001919 0.001145
Nuclear Periphery Foci 0.000258 0.000342 0.020538 0.002937 0.000353 0.000228 0.001702 0.003130 0.000295 0.000280 0.002941 0.003040
Nucleolus 0.000621 0.001669 0.005688 0.001102 0.000928 0.000591 0.001479 0.001254 0.000740 0.001088 0.001756 0.001183
Nucleus 0.004894 0.012302 0.081954 0.024182 0.005154 0.005732 0.010956 0.020748 0.004995 0.008759 0.015627 0.022346
Peroxisomes 0.005030 0.002287 0.022157 0.014552 0.007215 0.003283 0.010192 0.022830 0.005877 0.002824 0.010979 0.018977
Vacuole 0.337482* 0.649611* 0.252023* 0.306024* 0.442830* 0.686941* 0.341423* 0.298308* 0.378353* 0.669740* 0.335541* 0.301900*
Vacuole Periphery 0.024137 0.029630 0.004440 0.004840 0.023333 0.027275 0.008512 0.004060 0.023825 0.028360 0.008244 0.004423

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.48 -5.16 -4.52 -4.61 -1.30 -0.70 -3.90 -2.53 -2.50 -1.46 0.48 -4.45 -4.49 -4.50 -2.54
Bud Neck 3.66 0.35 0.90 -2.67 0.05 0.57 -3.75 -3.20 -3.51 -0.38 3.04 -2.87 -1.68 -4.39 0.91
Bud Site -0.29 -1.88 -9.82 -9.27 -5.54 -1.81 -7.74 -7.92 -6.44 -3.74 -1.11 -6.97 -12.34 -11.19 -7.66
Cell Periphery -4.71 -6.29 -1.83 3.53 5.60 -5.44 5.21 2.28 5.88 -5.50 -6.24 7.23 1.08 6.44 -6.67
Cytoplasm 2.53 -2.99 -21.76 -21.07 -8.34 7.67 -12.80 -24.46 -29.03 -16.43 7.89 -12.05 -32.26 -35.51 -21.09
Cytoplasmic Foci 26.71 2.65 25.21 -2.36 7.56 21.84 2.89 8.46 -13.77 7.27 36.10 8.71 23.12 -11.89 14.21
Eisosomes 11.42 -5.71 8.82 -4.07 9.06 0.91 9.57 4.27 1.46 -8.12 5.70 14.25 9.62 0.12 -6.11
Endoplasmic Reticulum -1.37 -6.02 3.05 4.60 6.86 -5.72 0.24 2.09 7.17 2.18 -3.74 0.60 4.00 8.32 4.24
Endosome 21.29* 7.86 39.99* 13.24 8.04 9.49 6.05 18.26 7.85 14.57 21.94* 13.59 39.49* 14.09 22.81
Golgi 17.30 13.41 14.57 -0.93 0.87 8.66 5.14 9.63 1.11 6.98 17.22 8.85 17.24 0.44 8.43
Lipid Particles 7.91 -3.44 10.48 0.40 5.36 5.62 -0.44 5.82 -0.87 10.91 10.31 0.64 12.15 -0.31 12.06
Mitochondria 11.25 14.55 13.85 2.73 -0.93 6.34 3.65 6.57 1.00 5.28 12.55 8.00 13.66 2.18 8.35
Mitotic Spindle 1.91 -4.20 -13.06 -13.34 -1.92 0.90 -20.63* -10.49 -10.80 5.81 2.08 -21.29 -16.68 -17.09 2.73
None -2.26 -3.27 -5.22 0.05 2.14 0.34 1.01 -2.86 -3.23 -5.25 -1.80 -0.94 -5.80 -1.77 -5.39
Nuclear Periphery -2.87 -7.34 -12.36 -7.93 4.40 1.22 -14.08 -5.59 -6.19 3.37 -1.92 -17.01 -10.84 -9.57 4.64
Nuclear Periphery Foci -0.64 -6.15 -8.85 -8.96 5.40 1.04 -8.07 -4.21 -4.42 -1.17 0.11 -9.50 -7.88 -8.01 1.24
Nucleolus -4.30 -5.17 -4.27 1.90 4.69 1.39 -3.52 -2.50 -4.39 1.15 -1.77 -9.15 -5.06 -1.94 4.83
Nucleus -4.60 -7.63 -16.04 -9.63 4.65 -0.68 -11.86 -14.80 -12.46 -7.63 -4.00 -14.18 -21.87 -15.58 -7.21
Peroxisomes 6.89 -3.73 -4.27 -7.12 2.73 5.25 -3.19 -5.21 -7.79 -3.69 7.58 -7.21 -7.00 -10.10 -1.93
Vacuole -29.32* 3.85 -7.12 18.98 -7.43 -21.08 8.33 7.47 28.95 0.35 -37.73* 3.09 -0.73 33.94 -3.47
Vacuole Periphery -3.45 21.70 25.98* 18.60 2.16 -2.69 15.78 19.35 20.80 8.98 -4.29 26.92 32.86 27.80 10.71
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; relocalizes from nucleus to vacuole upon DNA replication stress
Localization
Cell Percentages vacuole (83%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ktr3

Ktr3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ktr3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available