Standard name
Human Ortholog
Description RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0.06 0.07 0.06 0 0 0 0.2 0 – 0 0 0 0 0 0
Cytoplasm 1.0 0.99 0.98 0.98 0.89 0.87 0.86 – 0.76 0.68 0.67 0.61 1.0 1.0 0.99 0.98 0.94 – 0.95 0.96 0.91 0.94 0.94 0.94
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0.09 0 0 0 0 0 0 0 0.06 – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.07 – 0.13 0.12 0.27 0.21 0 0 0 0 0 – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.09 0.09 0.08 – 0.05 0.18 0.09 0.21 0 0 0 0 0.06 – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 1 0 2 0 – 1 4 1 2 0 0 0 0 0 – 0 0 1 0 0 0
Bud 0 0 0 0 1 2 1 – 0 0 1 1 0 0 0 0 0 – 0 0 0 0 0 1
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 1 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 6 6 7 7 6 7 – 3 12 13 13 0 7 4 10 0 – 0 0 0 0 0 0
Cytoplasm 17 209 162 164 192 229 229 – 123 136 123 127 186 251 344 50 17 – 49 199 150 76 194 207
Endoplasmic Reticulum 0 1 0 0 4 7 4 – 15 6 8 4 0 1 0 0 1 – 0 1 2 1 1 2
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 – 0 0 0 0 3 0
Golgi 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 – 0 1 1 0 0 0
Mitochondria 0 0 0 0 0 6 19 – 21 24 49 44 0 0 0 0 0 – 0 0 1 0 1 1
Nucleus 0 1 1 0 2 1 1 – 1 2 1 3 1 0 1 0 0 – 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 2 0 2 0 0 0 0 0 – 0 0 0 0 0 1
Nucleolus 0 0 0 0 1 0 1 – 0 0 0 1 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0 1 5 3 20 24 20 – 8 35 16 44 0 0 3 0 1 – 0 3 1 0 0 0
Unique Cell Count 17 212 166 167 216 264 265 161 200 183 208 186 252 347 51 18 52 209 165 82 208 220
Labelled Cell Count 17 220 174 175 227 277 282 172 221 212 241 187 259 353 61 19 52 209 165 82 208 220


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.3 11.2 11.1 10.3 11.9 10.3 10.3 – 8.9 10.0 8.5 9.2 10.6 11.1 11.0 14.6 12.4 – 9.2 10.5 10.9
Std Deviation (1e-4) 1.2 1.7 2.0 2.2 2.4 1.8 1.8 – 2.0 2.3 2.1 2.2 1.5 1.4 1.5 1.9 1.9 – 1.8 1.6 1.7
Intensity Change (Log2) – – – -0.1 0.1 -0.11 -0.11 – -0.31 -0.15 -0.39 -0.27 -0.06 0.01 -0.02 0.39 0.17 – -0.26 -0.08 -0.03

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Cell Periphery 0.3 -0.2 0 -0.6 – 0 1.1 1.4 1.2 0 -0.5 0 0 0 –
Cytoplasm 0.4 -3.2 -3.8 -3.9 – -5.7 -7.2 -7.3 -8.4 2.1 1.9 1.4 0.2 -0.8 –
Endoplasmic Reticulum 0 0 0 0 – 4.0 0 0 0 0 0 0 0 0 –
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Mitochondria 0 0 0 3.5 – 4.8 4.6 7.2 6.3 0 0 0 0 0 –
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 –
Vacuole 0 2.4 2.4 2.0 – 0.9 4.4 2.2 5.2 0 0 0 0 0 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.5299 5.3963 5.3157 5.2003 3.4751 5.2344 6.1797 7.6477 6.9097 6.2253 5.9414 7.2387 7.6508 8.4193 7.6815 7.7508 7.2862 7.8984
Actin 0.0057 0.0084 0.0071 0.0004 0.0036 0.0138 0.0323 0.0007 0.003 0.0354 0.0473 0.0019 0.0212 0.0006 0.002 0.0002 0.0006 0.0008
Bud 0.0002 0.0002 0.0023 0.0001 0.0007 0.0004 0.0034 0.0054 0.0034 0.0043 0.0004 0.0015 0.0004 0.0011 0.0005 0.0001 0.0001 0.0005
Bud Neck 0.007 0.0003 0.0003 0.0003 0.0009 0.0011 0.0016 0.0001 0.0003 0.0015 0.0011 0.0012 0.0022 0.0002 0.0003 0.0003 0.0003 0.0009
Bud Periphery 0.0001 0.0001 0.001 0 0.0003 0.0004 0.0018 0.0017 0.0013 0.0031 0.0006 0.0005 0.0005 0.0004 0.0006 0 0 0.0003
Bud Site 0.0037 0.0012 0.001 0 0.0114 0.0007 0.0117 0.005 0.0013 0.02 0.0008 0.0001 0.001 0.0008 0.0003 0 0.0002 0.0001
Cell Periphery 0.0002 0.0002 0.0001 0 0.0001 0.0001 0.0003 0.0001 0.0002 0.0003 0.0001 0 0.0001 0.0001 0.0001 0 0 0
Cytoplasm 0.85 0.9186 0.9054 0.9462 0.847 0.9275 0.7858 0.9708 0.9124 0.8048 0.825 0.9638 0.8951 0.9872 0.965 0.9865 0.9288 0.9811
Cytoplasmic Foci 0.0312 0.0044 0.0176 0.0026 0.0457 0.0069 0.0382 0.0027 0.0143 0.0185 0.029 0.0106 0.0129 0.0022 0.0043 0.002 0.0116 0.0032
Eisosomes 0.0001 0.0001 0.0001 0 0 0.0001 0.0002 0 0 0.0001 0.0002 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0139 0.0033 0.0027 0.0364 0.0039 0.0053 0.0159 0.0019 0.0086 0.0092 0.0016 0.0053 0.0108 0.0013 0.005 0.0028 0.0033 0.0022
Endosome 0.0168 0.007 0.0096 0.003 0.0509 0.009 0.0259 0.0011 0.0123 0.0202 0.0076 0.0047 0.0209 0.0009 0.0075 0.002 0.0234 0.0035
Golgi 0.0097 0.0101 0.0134 0.0001 0.021 0.0039 0.0087 0.0001 0.0109 0.0045 0.02 0.0019 0.003 0.0001 0.0013 0.0001 0.0013 0.0004
Lipid Particles 0.0066 0.0009 0.0026 0 0.0015 0.0051 0.007 0 0.0027 0.0179 0.0095 0 0.0012 0 0.0012 0 0.0067 0.0005
Mitochondria 0.001 0.0017 0.01 0.0001 0.0028 0.0014 0.0086 0.0008 0.0013 0.0193 0.0127 0.0012 0.0031 0.0001 0.0008 0.0001 0.0005 0.0002
None 0.0292 0.0363 0.0124 0.0018 0.0014 0.0013 0.0158 0.006 0.0143 0.0077 0.0036 0.0021 0.0075 0.0018 0.0029 0.0014 0.0034 0.0016
Nuclear Periphery 0.0032 0.0026 0.0009 0.0043 0.0009 0.0065 0.0168 0.0008 0.0007 0.0035 0.0009 0.0009 0.0088 0.0005 0.0011 0.0008 0.005 0.0008
Nucleolus 0.0007 0.0001 0 0 0.0001 0.0006 0.0005 0.0001 0.0001 0.0005 0.0001 0 0.0004 0 0.0001 0 0.0002 0
Nucleus 0.0019 0.002 0.001 0.0034 0.0012 0.0027 0.0048 0.0016 0.0014 0.005 0.0008 0.0014 0.0036 0.0021 0.0019 0.0025 0.0048 0.0024
Peroxisomes 0.0076 0.0002 0.01 0 0.0037 0.0011 0.0129 0.0001 0.0094 0.0177 0.0083 0.0016 0.0023 0 0.0009 0 0.0012 0.0003
Punctate Nuclear 0.0093 0.0006 0.0014 0.0001 0.0008 0.0103 0.0046 0.0005 0.0007 0.0014 0.0295 0.0004 0.0022 0.0002 0.0005 0.0001 0.0067 0.0005
Vacuole 0.0013 0.0013 0.0008 0.0007 0.0016 0.0015 0.0022 0.0005 0.0013 0.0037 0.0004 0.0005 0.0017 0.0003 0.003 0.001 0.0012 0.0004
Vacuole Periphery 0.0005 0.0003 0.0002 0.0002 0.0006 0.0005 0.0013 0.0001 0.0002 0.0012 0.0003 0.0002 0.0009 0.0001 0.0007 0.0002 0.0005 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 33.6104 35.1754 26.1016 35.9651 28.6973 40.4194 40.7525 42.508 38.8957 36.6677
Translational Efficiency 1.3108 1.3691 1.607 1.2707 1.4354 1.3969 1.1792 1.3567 1.4003 1.3031

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1963 1271 2724 1629 1856 1721 1301 1439 3819 2992 4025 3068

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 665.97 791.67 882.90 902.22 746.93 765.38 899.01 886.37 705.32 776.55 888.11 894.79
Standard Deviation 68.95 106.96 97.23 122.93 82.05 100.62 105.93 116.28 85.75 104.17 100.41 120.12
Intensity Change Log 2 — 0.249442 0.406793 0.438022 — 0.035203 0.267364 0.246936 — 0.140156 0.334765 0.340163

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000345 0.000362 0.000144 0.012537 0.000208 0.000281 0.000227 0.007686 0.000279 0.000315 0.000171 0.010262
Bud Neck 0.028545 0.011407 0.014518 0.012359 0.021622 0.020513 0.009524 0.012041 0.025181 0.016645 0.012904 0.012210
Bud Site 0.008006 0.012278 0.008330 0.107315 0.007623 0.014911 0.006263 0.086269 0.007820 0.013793 0.007662 0.097444
Cell Periphery 0.000098 0.000086 0.000041 0.000150 0.000052 0.000072 0.000063 0.000174 0.000076 0.000078 0.000048 0.000161
Cytoplasm 0.245628 0.377085 0.580945 0.435641 0.214676 0.240878 0.480296 0.397511 0.230585 0.298738 0.548412 0.417757
Cytoplasmic Foci 0.432174 0.309911 0.044110 0.066154 0.368848 0.262388 0.073291 0.079033 0.401398 0.282576 0.053542 0.072194
Eisosomes 0.000270 0.000084 0.000018 0.000065 0.000113 0.000086 0.000035 0.000061 0.000194 0.000085 0.000024 0.000063
Endoplasmic Reticulum 0.001024 0.001548 0.001457 0.001028 0.001220 0.001855 0.001144 0.000987 0.001120 0.001725 0.001356 0.001009
Endosome 0.108826 0.081525 0.018835 0.022597 0.170413 0.152033 0.045328 0.034190 0.138757 0.122081 0.027399 0.028035
Golgi 0.024451 0.007735 0.000199 0.007793 0.018287 0.015784 0.000348 0.006668 0.021456 0.012365 0.000247 0.007265
Lipid Particles 0.023775 0.010569 0.002638 0.001588 0.023292 0.013316 0.002850 0.001814 0.023540 0.012149 0.002706 0.001694
Mitochondria 0.007174 0.004278 0.001372 0.002605 0.007974 0.008881 0.000338 0.010941 0.007563 0.006926 0.001038 0.006515
Mitotic Spindle 0.001873 0.006498 0.021471 0.070329 0.005761 0.010774 0.016217 0.091958 0.003763 0.008957 0.019773 0.080474
None 0.001223 0.001988 0.002981 0.002136 0.000406 0.000831 0.002318 0.002045 0.000826 0.001323 0.002767 0.002093
Nuclear Periphery 0.000240 0.000483 0.003554 0.000939 0.000251 0.000464 0.001335 0.000639 0.000245 0.000472 0.002836 0.000799
Nuclear Periphery Foci 0.000519 0.001709 0.002455 0.001786 0.000677 0.001011 0.003561 0.001405 0.000596 0.001308 0.002813 0.001608
Nucleolus 0.000853 0.001001 0.002302 0.000606 0.000894 0.001033 0.001704 0.001728 0.000873 0.001020 0.002109 0.001132
Nucleus 0.020907 0.032063 0.170705 0.052545 0.016491 0.014521 0.074671 0.036430 0.018761 0.021973 0.139664 0.044986
Peroxisomes 0.020006 0.007596 0.002149 0.040934 0.012846 0.009572 0.003388 0.037180 0.016526 0.008733 0.002550 0.039173
Vacuole 0.071612 0.127942 0.121387 0.157354 0.123979 0.220243 0.276346 0.184542 0.097062 0.181034 0.171475 0.170106
Vacuole Periphery 0.002450 0.003851 0.000388 0.003539 0.004364 0.010551 0.000752 0.006698 0.003380 0.007705 0.000506 0.005021

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.27 4.35 -6.59 -6.57 -6.74 -1.91 -0.82 -4.69 -4.59 -4.61 -1.07 2.63 -8.04 -7.99 -8.16
Bud Neck 9.62 4.78 10.07 0.30 7.19 0.67 7.29 7.61 6.97 -0.55 6.78 6.90 12.61 6.24 6.26
Bud Site -3.37 1.04 -14.78 -13.19 -15.00 -6.71 1.08 -12.35 -9.81 -12.49 -7.22 1.35 -19.25 -16.28 -19.44
Cell Periphery 1.06 4.98 -1.25 -3.25 -8.82 -3.22 -1.17 -4.17 -2.23 -3.68 -0.42 4.78 -3.71 -3.80 -8.56
Cytoplasm -12.97 -33.05 -17.04 -2.44 11.03 -3.26 -23.24 -16.64 -13.44 6.45 -10.46 -42.08 -23.86 -12.30 13.63
Cytoplasmic Foci 14.95 68.24 64.19 36.03 -2.59 14.98 51.10 52.48 34.09 1.55 22.01 85.96 82.19 49.77 -1.84
Eisosomes 11.25 16.20 12.70 1.78 -11.94 3.92 13.40 9.25 6.30 -4.57 11.91 19.81 14.97 5.14 -13.02
Endoplasmic Reticulum -2.88 -5.84 -1.54 1.95 5.76 -2.33 0.22 1.35 3.06 1.32 -3.44 -5.38 -0.40 3.45 6.36
Endosome 5.67 23.63 25.48 17.62 4.38 3.01 25.82 31.53 29.28 5.42 4.26 36.45 40.09 33.96 6.03
Golgi 11.25 18.95 14.91 4.39 -3.70 1.69 18.92 14.56 10.88 -4.52 8.51 26.34 20.47 11.28 -5.60
Lipid Particles 9.66 17.48 18.27 10.91 3.10 5.64 14.70 15.09 9.95 2.16 9.99 22.53 23.42 13.76 3.72
Mitochondria 3.09 8.67 8.66 3.66 0.63 -0.76 9.17 2.80 3.41 -4.12 0.86 12.22 6.82 5.36 -3.55
Mitotic Spindle -4.07 -12.14 -12.28 -10.43 -4.92 -2.46 -3.94 -12.22 -10.64 -8.32 -4.31 -11.55 -17.24 -14.57 -9.21
None -1.36 -6.32 -3.53 -0.66 3.48 -1.77 -7.86 -8.78 -4.23 -0.10 -1.75 -11.30 -7.67 -3.30 2.88
Nuclear Periphery -3.46 -19.34 -8.71 -7.40 13.23 -2.02 -14.61 -16.06 -7.49 3.24 -3.37 -21.80 -14.30 -9.95 14.07
Nuclear Periphery Foci -3.15 -8.69 -5.01 0.19 3.24 -0.76 -6.15 -5.59 -1.81 4.54 -2.73 -10.38 -7.10 -1.18 5.69
Nucleolus -2.10 -9.01 1.13 2.75 9.22 -0.57 -5.08 -1.66 -1.29 1.06 -1.41 -10.05 -1.34 -0.43 7.10
Nucleus -5.81 -44.48 -19.31 -12.82 23.99 1.39 -20.60 -16.28 -16.57 4.25 -3.32 -47.64 -25.26 -21.70 24.02
Peroxisomes 10.27 16.15 -0.97 -6.64 -9.31 2.99 9.94 -3.41 -4.79 -7.56 9.22 19.54 -3.07 -7.92 -12.12
Vacuole -12.52 -20.41 -29.82 -19.38 -16.16 -14.90 -22.43 -22.12 -9.33 -0.24 -20.08 -26.56 -36.35 -18.12 -14.26
Vacuole Periphery -2.61 16.65 3.32 4.26 -2.74 -7.63 14.29 2.45 7.73 -2.89 -8.39 20.62 3.81 9.42 -3.92
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase
Localization
Cell Percentages cytoplasm (54%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ngr1

Ngr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ngr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available