Standard name | |
---|---|
Human Ortholog | |
Description | Tyrosyl-DNA phosphodiesterase I; hydrolyzes 3' and 5'-phosphotyrosyl bonds; involved in the repair of DNA lesions created by topo I and topo II; mutations in the human homolog, TDP1, result in the a neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy (SCAN1); yeast cells and human rhabdomyosarcoma lines that overexpress TDP1 both exhibit elevated dosage chromosomal instability (dCIN) |
ensLOC | DeepLoc | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 6 | 1 | 1 | 4 |
Bud | 1 | 0 | 1 | 3 | 3 | 3 | 5 | 10 | 3 | 10 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 4 | 11 | 10 | 17 |
Bud Neck | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 3 | 2 | 3 | 7 |
Bud Site | 0 | 0 | 0 | 1 | 0 | 3 | 5 | 8 | 4 | 12 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoplasm | 56 | 163 | 178 | 113 | 117 | 112 | 150 | 184 | 83 | 118 | 25 | 26 | 199 | 297 | 279 | 195 | 161 | 117 | 56 | 110 | 123 | 92 | 72 | 33 |
Endoplasmic Reticulum | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 17 | 22 | 14 | 1 | 0 | 4 | 1 | 1 | 5 |
Endosome | 2 | 4 | 2 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 24 | 38 | 11 | 16 | 19 | 4 | 4 | 3 | 4 | 10 | 12 |
Golgi | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 1 | 2 | 1 | 1 | 0 | 2 | 1 | 3 | 1 |
Mitochondria | 41 | 16 | 73 | 89 | 114 | 232 | 315 | 331 | 253 | 287 | 115 | 96 | 15 | 29 | 14 | 23 | 14 | 14 | 8 | 9 | 26 | 20 | 19 | 10 |
Nucleus | 13 | 80 | 13 | 22 | 23 | 57 | 42 | 82 | 65 | 65 | 30 | 23 | 200 | 144 | 119 | 17 | 26 | 17 | 45 | 146 | 42 | 182 | 189 | 177 |
Nuclear Periphery | 2 | 2 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Nucleolus | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 6 | 5 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
SpindlePole | 0 | 1 | 2 | 1 | 2 | 0 | 2 | 2 | 2 | 3 | 1 | 0 | 0 | 0 | 1 | 0 | 2 | 1 | 5 | 10 | 10 | 22 | 46 | 34 |
Vac/Vac Membrane | 34 | 125 | 36 | 30 | 19 | 11 | 13 | 21 | 9 | 10 | 11 | 3 | 147 | 284 | 283 | 71 | 94 | 86 | 57 | 126 | 107 | 94 | 116 | 139 |
Unique Cell Count | 128 | 332 | 271 | 216 | 232 | 327 | 427 | 515 | 324 | 382 | 135 | 123 | 523 | 726 | 664 | 301 | 287 | 229 | 194 | 428 | 352 | 449 | 500 | 469 |
Labelled Cell Count | 149 | 394 | 308 | 259 | 281 | 420 | 534 | 645 | 421 | 508 | 186 | 155 | 570 | 785 | 738 | 338 | 339 | 269 | 194 | 428 | 352 | 449 | 500 | 469 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 3.8 | 4.3 | 3.5 | 3.2 | 3.5 | 3.0 | 2.6 | 2.9 | 2.8 | 2.6 | 2.7 | 2.7 | 4.5 | 4.4 | 4.5 | 5.1 | 6.4 | 5.7 | 4.1 | 4.3 | 5.1 |
Std Deviation (1e-4) | 1.0 | 0.7 | 0.7 | 0.6 | 1.3 | 0.9 | 0.9 | 1.0 | 1.1 | 0.9 | 0.6 | 1.1 | 1.0 | 1.3 | 1.3 | 1.9 | 2.4 | 1.7 | 1.2 | 1.7 | 1.3 |
Intensity Change (Log2) | – | – | – | -0.12 | -0.01 | -0.23 | -0.42 | -0.27 | -0.29 | -0.42 | -0.35 | -0.35 | 0.36 | 0.35 | 0.36 | 0.56 | 0.88 | 0.7 | 0.23 | 0.3 | 0.56 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Endosome | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Golgi | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | 3.2 | 5.4 | 6.3 |
R1 | R2 | R3 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Concentration | 2.8797 | 2.532 | 2.6713 | 2.7305 | 2.3306 | 2.4958 | 2.3028 | 1.6176 | 1.948 | 1.955 | 1.4932 | 1.7819 | 2.7657 | 2.6211 | 2.9292 | 2.0457 | 2.4336 | 2.7095 |
Actin | 0.006 | 0.0097 | 0.0021 | 0.0008 | 0.0249 | 0.0016 | 0.0349 | 0.0008 | 0.0038 | 0.0224 | 0.0003 | 0.0062 | 0.0574 | 0.0087 | 0.026 | 0.0005 | 0.0315 | 0.0031 |
Bud | 0.0003 | 0.0033 | 0.0011 | 0.0001 | 0.0004 | 0.0003 | 0.0012 | 0.0011 | 0.0006 | 0.0003 | 0.0001 | 0.0002 | 0.0006 | 0.0002 | 0.0006 | 0.0001 | 0.0002 | 0.0003 |
Bud Neck | 0.0017 | 0.0008 | 0.0057 | 0.0008 | 0.0059 | 0.0027 | 0.0027 | 0.0005 | 0.0014 | 0.0006 | 0.0006 | 0.0029 | 0.0021 | 0.0005 | 0.004 | 0.0003 | 0.0009 | 0.0113 |
Bud Periphery | 0.0003 | 0.0089 | 0.0016 | 0.0001 | 0.0007 | 0.0004 | 0.0015 | 0.0021 | 0.0007 | 0.0004 | 0 | 0.0002 | 0.001 | 0.0002 | 0.0013 | 0.0001 | 0.0003 | 0.0007 |
Bud Site | 0.0021 | 0.0054 | 0.0029 | 0.0003 | 0.0038 | 0.0003 | 0.0069 | 0.0013 | 0.0097 | 0.0006 | 0.0001 | 0.0012 | 0.0017 | 0.0017 | 0.0151 | 0.0002 | 0.0003 | 0.0003 |
Cell Periphery | 0.0003 | 0.0004 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0002 | 0.0001 | 0 | 0 | 0.0002 | 0.0001 | 0.0004 | 0 | 0.0001 | 0.0001 |
Cytoplasm | 0.1293 | 0.2368 | 0.1235 | 0.1498 | 0.1954 | 0.1442 | 0.1051 | 0.1929 | 0.1342 | 0.1125 | 0.124 | 0.1555 | 0.1138 | 0.2129 | 0.1118 | 0.2439 | 0.115 | 0.1501 |
Cytoplasmic Foci | 0.0215 | 0.0088 | 0.0191 | 0.0064 | 0.0117 | 0.0096 | 0.0371 | 0.0059 | 0.0126 | 0.0088 | 0.0087 | 0.0149 | 0.0152 | 0.0037 | 0.0178 | 0.0034 | 0.0109 | 0.0107 |
Eisosomes | 0.0002 | 0.0002 | 0.0002 | 0.0001 | 0.0005 | 0.0001 | 0.0004 | 0.0001 | 0.0002 | 0.0001 | 0.0001 | 0.0001 | 0.0005 | 0.0002 | 0.0004 | 0 | 0.0004 | 0.0001 |
Endoplasmic Reticulum | 0.0061 | 0.0078 | 0.0024 | 0.0037 | 0.0031 | 0.0035 | 0.0075 | 0.0036 | 0.0026 | 0.002 | 0.002 | 0.0026 | 0.0078 | 0.0023 | 0.0041 | 0.0059 | 0.0044 | 0.0031 |
Endosome | 0.0224 | 0.0073 | 0.0094 | 0.0113 | 0.006 | 0.0074 | 0.0633 | 0.0046 | 0.0121 | 0.0126 | 0.0111 | 0.0091 | 0.0274 | 0.0031 | 0.0097 | 0.0053 | 0.015 | 0.0038 |
Golgi | 0.0034 | 0.0015 | 0.0017 | 0.0002 | 0.0032 | 0.0027 | 0.0248 | 0.0004 | 0.0049 | 0.0177 | 0.0078 | 0.0038 | 0.0142 | 0.0018 | 0.0056 | 0.0001 | 0.008 | 0.0003 |
Lipid Particles | 0.0137 | 0.0018 | 0.004 | 0.0006 | 0.0174 | 0.0016 | 0.0238 | 0.0006 | 0.0134 | 0.0044 | 0.0195 | 0.0039 | 0.0151 | 0.0015 | 0.0095 | 0.0002 | 0.0184 | 0.0005 |
Mitochondria | 0.0017 | 0.0081 | 0.0119 | 0.001 | 0.0067 | 0.0074 | 0.0114 | 0.0018 | 0.0264 | 0.0162 | 0.0032 | 0.0104 | 0.0035 | 0.0013 | 0.0057 | 0.0009 | 0.0029 | 0.0007 |
None | 0.392 | 0.3121 | 0.4584 | 0.4158 | 0.418 | 0.2674 | 0.3316 | 0.3914 | 0.3712 | 0.3379 | 0.3901 | 0.2906 | 0.4396 | 0.4497 | 0.4453 | 0.3551 | 0.3939 | 0.2971 |
Nuclear Periphery | 0.0268 | 0.019 | 0.01 | 0.0251 | 0.0091 | 0.019 | 0.0167 | 0.0116 | 0.0117 | 0.01 | 0.0125 | 0.0089 | 0.0353 | 0.0068 | 0.0148 | 0.0222 | 0.014 | 0.0129 |
Nucleolus | 0.0107 | 0.0039 | 0.0043 | 0.0026 | 0.0056 | 0.0058 | 0.0025 | 0.0035 | 0.0044 | 0.0026 | 0.003 | 0.0046 | 0.0033 | 0.0024 | 0.0035 | 0.0014 | 0.0021 | 0.0041 |
Nucleus | 0.2989 | 0.3118 | 0.2937 | 0.3355 | 0.2488 | 0.4468 | 0.2434 | 0.3447 | 0.3291 | 0.3803 | 0.3899 | 0.4292 | 0.2177 | 0.2863 | 0.2717 | 0.3474 | 0.3419 | 0.4555 |
Peroxisomes | 0.0037 | 0.0008 | 0.0044 | 0.0002 | 0.0219 | 0.0009 | 0.0294 | 0.0011 | 0.0111 | 0.021 | 0.0057 | 0.0114 | 0.0071 | 0.0008 | 0.0143 | 0.0001 | 0.0185 | 0.0003 |
Punctate Nuclear | 0.0551 | 0.0443 | 0.0385 | 0.0316 | 0.0139 | 0.0742 | 0.0473 | 0.0289 | 0.0468 | 0.0472 | 0.0198 | 0.0426 | 0.0304 | 0.0135 | 0.0355 | 0.0094 | 0.0196 | 0.043 |
Vacuole | 0.003 | 0.006 | 0.004 | 0.0125 | 0.0022 | 0.0024 | 0.0051 | 0.0026 | 0.0023 | 0.0015 | 0.0011 | 0.0013 | 0.0047 | 0.002 | 0.0021 | 0.0028 | 0.0006 | 0.0017 |
Vacuole Periphery | 0.0009 | 0.0011 | 0.0008 | 0.0012 | 0.0005 | 0.0017 | 0.0032 | 0.0005 | 0.0007 | 0.0009 | 0.0004 | 0.0003 | 0.0015 | 0.0003 | 0.0007 | 0.0006 | 0.0009 | 0.0005 |
R1 | R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Gene Expression | 6.0738 | 4.223 | 3.5813 | 7.6698 | 5.6874 | 4.0469 | 7.4723 | 6.5872 | 8.2738 | 8.1087 |
Translational Efficiency | – | – | – | – | – | – | – | – | – | – |
Dataset | Hit |
---|---|
Protein Concentration | ✘ |
Protein Localization | ✘ |
Gene Expression | ✘ |
Translational Efficiency | – |
R1 | R2 | R1 & R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
215 | 2066 | 627 | 1853 | 721 | 1550 | 191 | 1017 | 936 | 3616 | 818 | 2870 |
R1 | R2 | R1 & R2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
Mean | 637.54 | 677.55 | 810.28 | 839.24 | 702.07 | 718.71 | 845.26 | 959.56 | 687.25 | 695.19 | 818.45 | 881.88 |
Standard Deviation | 65.80 | 86.16 | 97.16 | 108.67 | 76.67 | 91.36 | 99.30 | 179.80 | 79.12 | 90.75 | 98.78 | 149.64 |
Intensity Change Log 2 | — | 0.087812 | 0.345905 | 0.396568 | — | 0.033795 | 0.267780 | 0.450758 | — | 0.059755 | 0.305489 | 0.425222 |
R1 | R2 | R1 & R2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
Actin | 0.000025 | 0.000135 | 0.000217 | 0.002652 | 0.000446 | 0.000135 | 0.000517 | 0.000651 | 0.000349 | 0.000135 | 0.000288 | 0.001943 |
Bud Neck | 0.001253 | 0.017551 | 0.003549 | 0.021340 | 0.003216 | 0.016951 | 0.002094 | 0.029571 | 0.002765 | 0.017294 | 0.003209 | 0.024257 |
Bud Site | 0.001015 | 0.004744 | 0.002658 | 0.028630 | 0.002085 | 0.008025 | 0.001217 | 0.027960 | 0.001839 | 0.006150 | 0.002321 | 0.028393 |
Cell Periphery | 0.000117 | 0.000113 | 0.000079 | 0.000248 | 0.000187 | 0.000141 | 0.000121 | 0.014636 | 0.000171 | 0.000125 | 0.000089 | 0.005346 |
Cytoplasm | 0.198537* | 0.319619* | 0.027700 | 0.173205* | 0.274277* | 0.315812* | 0.074123 | 0.334555* | 0.256880* | 0.317987* | 0.038539 | 0.230380* |
Cytoplasmic Foci | 0.030421 | 0.065627 | 0.000672 | 0.002350 | 0.085207 | 0.060758 | 0.004564 | 0.010236 | 0.072623 | 0.063540 | 0.001581 | 0.005144 |
Eisosomes | 0.000046 | 0.000045 | 0.000023 | 0.000028 | 0.000082 | 0.000044 | 0.000041 | 0.005368 | 0.000074 | 0.000045 | 0.000027 | 0.001921 |
Endoplasmic Reticulum | 0.000260 | 0.001352 | 0.003845 | 0.004440 | 0.000830 | 0.001075 | 0.007253 | 0.001843 | 0.000699 | 0.001233 | 0.004641 | 0.003519 |
Endosome | 0.001562 | 0.004190 | 0.000501 | 0.003350 | 0.002312 | 0.004771 | 0.001607 | 0.000807 | 0.002140 | 0.004439 | 0.000759 | 0.002449 |
Golgi | 0.000157 | 0.001255 | 0.000032 | 0.002230 | 0.001253 | 0.001055 | 0.000663 | 0.000230 | 0.001001 | 0.001169 | 0.000179 | 0.001521 |
Lipid Particles | 0.002199 | 0.004348 | 0.000488 | 0.000668 | 0.007460 | 0.004434 | 0.005176 | 0.001292 | 0.006251 | 0.004385 | 0.001582 | 0.000889 |
Mitochondria | 0.000611 | 0.007190 | 0.000466 | 0.006144 | 0.005403 | 0.007495 | 0.000674 | 0.002605 | 0.004302 | 0.007321 | 0.000514 | 0.004890 |
Mitotic Spindle | 0.001897 | 0.004392 | 0.002882 | 0.037853 | 0.003518 | 0.008523 | 0.000263 | 0.003673 | 0.003146 | 0.006163 | 0.002271 | 0.025741 |
None | 0.008305 | 0.010289 | 0.003886 | 0.009017 | 0.005127 | 0.011043 | 0.005121 | 0.040078 | 0.005857 | 0.010612 | 0.004174 | 0.020024 |
Nuclear Periphery | 0.000598 | 0.001381 | 0.001134 | 0.003268 | 0.001021 | 0.002038 | 0.001229 | 0.000691 | 0.000923 | 0.001663 | 0.001157 | 0.002355 |
Nuclear Periphery Foci | 0.000183 | 0.000533 | 0.000194 | 0.000604 | 0.000498 | 0.000319 | 0.000521 | 0.000477 | 0.000425 | 0.000441 | 0.000270 | 0.000559 |
Nucleolus | 0.002047 | 0.005158 | 0.001039 | 0.001561 | 0.001460 | 0.004249 | 0.000810 | 0.001287 | 0.001595 | 0.004768 | 0.000985 | 0.001464 |
Nucleus | 0.746223* | 0.526712* | 0.943824* | 0.673518* | 0.592864* | 0.525990* | 0.869686* | 0.509144* | 0.628091* | 0.526403* | 0.926513* | 0.615271* |
Peroxisomes | 0.000955 | 0.004192 | 0.000260 | 0.000566 | 0.002471 | 0.004809 | 0.000130 | 0.000570 | 0.002123 | 0.004457 | 0.000229 | 0.000567 |
Vacuole | 0.003404 | 0.020232 | 0.006458 | 0.027182 | 0.010040 | 0.020965 | 0.024073 | 0.013935 | 0.008515 | 0.020546 | 0.010571 | 0.022488 |
Vacuole Periphery | 0.000185 | 0.000942 | 0.000094 | 0.001144 | 0.000243 | 0.001369 | 0.000117 | 0.000391 | 0.000230 | 0.001125 | 0.000100 | 0.000877 |
R1 | R2 | R1 & R2 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
Actin | -5.53 | -7.21 | -3.68 | -3.34 | -2.88 | 0.96 | -0.80 | -0.17 | -1.03 | 0.48 | 0.83 | -0.22 | -1.93 | -3.41 | -2.40 |
Bud Neck | -10.70 | -2.91 | -12.66 | -0.76 | -10.50 | -8.51 | 0.58 | -10.27 | -3.62 | -11.05 | -12.51 | -1.27 | -15.05 | -2.86 | -14.56 |
Bud Site | -3.93 | -1.47 | -8.85 | -7.16 | -7.35 | -3.59 | -0.16 | -6.45 | -4.40 | -6.60 | -4.19 | -0.84 | -10.16 | -8.03 | -9.54 |
Cell Periphery | 0.25 | 2.11 | -4.01 | -4.83 | -5.89 | 0.96 | 0.99 | -9.03 | -9.08 | -9.09 | 1.23 | 1.96 | -8.82 | -8.97 | -9.04 |
Cytoplasm | -7.17 | 10.93 | 3.74 | 24.55 | -21.18 | -3.68 | 15.14 | -3.07 | 0.56 | -18.84 | -6.68 | 26.21 | 6.64 | 19.42 | -30.38 |
Cytoplasmic Foci | -7.98 | 8.72 | 8.38 | 22.96 | -4.76 | 4.28 | 15.04 | 15.02 | 18.03 | -1.86 | 2.00 | 17.33 | 16.79 | 29.51 | -4.34 |
Eisosomes | 0.18 | 3.63 | 1.47 | 2.67 | -4.19 | 5.71 | 2.07 | -4.91 | -4.97 | -4.94 | 5.51 | 6.59 | -4.80 | -4.92 | -4.95 |
Endoplasmic Reticulum | -10.86 | -12.87 | -23.89 | -19.16 | -3.64 | -0.95 | -9.56 | -2.63 | -2.43 | 8.67 | -2.81 | -13.45 | -15.53 | -17.74 | 3.21 |
Endosome | -2.87 | 1.17 | -0.35 | 4.95 | -5.05 | -3.23 | 0.84 | 3.00 | 8.49 | 1.97 | -4.04 | 2.76 | 1.51 | 8.60 | -2.70 |
Golgi | -3.67 | 1.60 | -1.46 | 1.06 | -1.81 | 0.29 | 1.22 | 1.80 | 3.07 | 0.66 | -0.39 | 1.90 | 0.84 | 1.90 | -1.60 |
Lipid Particles | -5.09 | 4.86 | 3.96 | 11.34 | -3.64 | 2.64 | 1.60 | 5.89 | 6.79 | 1.09 | 2.11 | 4.98 | 6.26 | 12.59 | 0.63 |
Mitochondria | -8.56 | 0.40 | -6.01 | 3.88 | -6.88 | -1.00 | 2.29 | 1.33 | 4.79 | -2.61 | -1.84 | 2.36 | 0.57 | 5.99 | -7.07 |
Mitotic Spindle | -1.08 | -0.36 | -8.30 | -8.70 | -8.41 | -2.16 | 1.71 | -2.60 | -0.72 | -4.81 | -1.87 | 0.34 | -8.58 | -8.08 | -8.91 |
None | -1.11 | 2.59 | 0.29 | 2.54 | -3.78 | -3.51 | 0.70 | -8.36 | -6.49 | -9.06 | -3.99 | 1.79 | -7.15 | -4.37 | -9.12 |
Nuclear Periphery | -9.17 | -6.96 | -22.24 | -18.07 | -17.66 | -2.52 | -3.78 | -3.05 | 1.48 | 0.92 | -3.95 | -4.52 | -19.00 | -10.06 | -15.82 |
Nuclear Periphery Foci | -3.31 | -0.60 | -4.17 | -2.46 | -3.99 | 1.10 | -1.72 | 0.30 | -1.32 | 1.96 | -0.29 | -0.39 | -2.45 | -2.88 | -2.27 |
Nucleolus | -3.48 | 1.89 | 1.08 | 6.79 | -2.50 | -4.47 | 2.98 | -1.07 | 2.95 | -2.42 | -7.17 | 3.15 | -0.14 | 7.07 | -3.34 |
Nucleus | 11.36 | -10.32 | 2.92 | -16.76 | 28.62 | 4.72 | -13.59 | 2.70 | -2.15 | 16.49 | 9.14 | -26.24 | -1.29 | -14.94 | 34.91 |
Peroxisomes | -5.77 | 1.61 | 1.64 | 10.23 | -0.03 | -2.97 | 6.25 | 5.60 | 7.15 | -1.96 | -4.94 | 6.08 | 6.04 | 12.15 | -0.61 |
Vacuole | -10.14 | -3.41 | -18.37 | -13.46 | -16.04 | -6.68 | -4.35 | -4.78 | 1.41 | 3.38 | -10.61 | -4.14 | -17.79 | -12.15 | -9.65 |
Vacuole Periphery | -5.53 | 1.11 | -2.48 | 2.87 | -3.91 | -4.62 | 2.82 | -0.62 | 3.80 | -1.58 | -7.05 | 3.42 | -2.39 | 4.68 | -4.13 |
Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
---|---|---|---|---|
37℃ | ||||
RT |
Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
---|
Gene | Images |
---|
Gene | Images |
---|