Standard name
Human Ortholog
Description UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p; UBX7 has a paralog, UBX6, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.38 0.34 0.27 0.26 0.33 0.22 0.19 0.2 0.17 0.19 0.17 0.15 0.37 0.39 0.47 0.4 0.37 0.37 0.09 0.18 0.07 0.17 0.13 0.11
Endoplasmic Reticulum 0 0.32 0.07 0.13 0 0.05 0 0 0 0 0 0 0.5 0.16 0.09 0 0 0 0.55 0.43 0.57 0.39 0.44 0.44
Endosome 0.09 0 0.21 0.09 0.14 0 0 0.07 0.06 0 0 0 0 0.05 0.06 0.06 0.05 0.1 0 0 0 0 0.05 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.33 0.08 0.13 0.29 0.31 0.59 0.6 0.44 0.4 0.55 0.58 0.61 0 0 0 0 0 0 0.1 0.09 0.09 0.12 0.08 0.08
Nucleus 0 0 0 0 0 0 0 0.06 0.05 0.07 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0.05 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0.09 0.09 0.15 0.08 0.1 0.11
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.42 0.33 0.52 0.36 0.35 0.27 0.34 0.43 0.48 0.34 0.37 0.36 0.2 0.48 0.49 0.52 0.5 0.54 0 0.09 0 0.1 0.1 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 0 1 0 0 1 1 1 0 0 0 0 0 2 5 6 2 3 8 22 5 6 8
Bud 2 4 3 2 17 12 26 25 29 27 36 28 0 1 1 1 2 1 4 6 2 5 7 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 3 2 2 3 7
Bud Site 0 0 0 0 0 3 2 2 2 15 4 4 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 3 2 2 2 4 6 5 6 5 2 8 3 5 11 5 0 0 0 0 1 2
Cytoplasm 50 95 139 81 137 187 187 157 168 203 161 153 95 203 244 121 105 101 18 68 44 69 66 61
Endoplasmic Reticulum 3 88 34 42 15 44 15 8 17 9 3 17 126 86 49 5 5 5 112 161 383 156 217 250
Endosome 12 5 108 30 59 16 12 54 57 37 21 13 8 26 29 19 15 28 6 10 15 15 24 41
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 2 0 6 2 3 5
Mitochondria 43 23 65 91 126 511 605 353 389 596 557 603 0 0 1 2 10 4 20 33 62 49 41 44
Nucleus 0 2 0 4 6 22 30 49 49 75 55 29 5 13 15 8 7 6 0 2 0 5 2 1
Nuclear Periphery 0 2 10 15 1 34 25 37 51 22 17 42 0 5 4 7 6 2 18 32 101 33 48 61
Nucleolus 0 0 2 0 0 0 4 14 3 11 4 3 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 0 0 0
SpindlePole 0 1 3 2 1 1 1 0 3 3 3 1 0 1 1 1 0 1 3 4 5 6 10 14
Vac/Vac Membrane 55 91 266 113 143 236 337 342 473 369 349 356 51 252 258 158 143 149 9 34 17 39 51 52
Unique Cell Count 130 279 514 316 413 863 1002 802 983 1074 954 994 254 523 522 306 284 276 204 378 677 398 495 570
Labelled Cell Count 165 313 635 384 507 1069 1247 1046 1248 1372 1216 1254 287 596 607 333 311 309 204 378 677 398 495 570


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 6.0 5.7 5.2 5.4 4.6 4.6 4.9 4.9 4.6 4.4 4.5 7.3 7.4 7.2 9.0 8.6 8.9 7.5 8.1 8.5
Std Deviation (1e-4) 0.8 0.9 0.9 1.4 1.4 1.0 1.0 1.2 1.1 1.0 1.0 1.0 0.9 1.0 1.0 1.6 1.4 1.6 1.2 1.3 1.4
Intensity Change (Log2) – – – -0.13 -0.09 -0.31 -0.33 -0.22 -0.22 -0.31 -0.37 -0.36 0.36 0.36 0.33 0.65 0.58 0.64 0.4 0.5 0.56

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 3.7 0 0 3.1 3.0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 2.0 -2.3 -3.8 -3.2 -4.5 -3.7 -4.6 -5.4 2.9 4.0 6.6 3.7 2.9 2.8
Endoplasmic Reticulum 3.2 -2.0 0 0 -5.7 -4.9 0 0 0 13.8 4.9 1.6 -3.2 -3.0 -3.0
Endosome -4.3 -2.6 0 0 -7.7 -8.9 0 0 0 -6.5 -7.7 -7.3 -5.7 -5.9 -3.9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 5.8 6.7 0 0 11.9 10.8 0 0 0 -5.9 -8.4 -8.2 -6.1 -4.2 -5.3
Nucleus 0 0 3.6 4.0 5.7 5.1 6.1 5.5 3.9 0 3.6 3.9 0 0 0
Nuclear Periphery 2.3 0 0 0 2.5 3.0 0 0 0 0 -1.3 -1.6 0.3 0.2 0
Nucleolus 0 0 0 0 2.2 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.5 -5.2 -9.1 -6.8 -3.2 -1.3 -6.6 -5.6 -6.0 -8.4 -1.1 -0.7 0 -0.4 0.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.2413 5.4979 5.4538 4.7235 4.8057 5.6133 3.9747 3.2534 3.4363 3.006 3.1618 3.6437 3.7571 2.8612 3.0809 2.7065 2.32 2.9511
Actin 0.0022 0.0008 0.0018 0.0015 0.0027 0.0015 0.0033 0.001 0.0027 0.0016 0.0107 0.0026 0.0346 0.0008 0.0017 0.0017 0.0435 0.0087
Bud 0.0001 0.0004 0.0018 0.0001 0.0011 0.0002 0.0002 0.002 0.0018 0.0001 0.0002 0.0001 0.0004 0.0032 0.0014 0.0078 0.0148 0.0017
Bud Neck 0.0003 0.0004 0.002 0.0027 0.0012 0.002 0.0032 0.0012 0.0029 0.002 0.0015 0.0028 0.0014 0.0005 0.001 0.0012 0.0078 0.004
Bud Periphery 0.0001 0.0002 0.0004 0.0001 0.0011 0.0002 0.0003 0.0004 0.0006 0.0001 0.0002 0.0002 0.0005 0.0005 0.0005 0.0023 0.0039 0.0009
Bud Site 0.0011 0.003 0.0015 0.0004 0.0012 0.0003 0.0023 0.0076 0.0026 0.0002 0.0007 0.0002 0.0028 0.0086 0.0083 0.0004 0.0013 0.0004
Cell Periphery 0.0005 0.0003 0.0003 0.0002 0.0003 0.0002 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001 0.0002 0.0002 0.0002 0.0002 0.0002 0.0002
Cytoplasm 0.1937 0.334 0.2579 0.1932 0.2967 0.2968 0.1681 0.2996 0.2176 0.199 0.1707 0.2135 0.1917 0.3624 0.2776 0.3829 0.3549 0.3532
Cytoplasmic Foci 0.007 0.008 0.0151 0.0106 0.0127 0.0125 0.0098 0.0049 0.0063 0.0054 0.0032 0.007 0.0207 0.0066 0.0115 0.0115 0.0163 0.0152
Eisosomes 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0 0 0 0 0.0001 0 0.0004 0 0.0001 0 0.0002 0.0001
Endoplasmic Reticulum 0.3013 0.1968 0.2482 0.314 0.2212 0.2654 0.2433 0.2452 0.2326 0.3205 0.2715 0.2595 0.1969 0.2659 0.2675 0.2161 0.194 0.2201
Endosome 0.0266 0.0349 0.0309 0.0453 0.0548 0.0333 0.0386 0.0247 0.0208 0.0264 0.0375 0.0234 0.052 0.0237 0.0331 0.0235 0.0394 0.0334
Golgi 0.0008 0.0006 0.0008 0.0007 0.0018 0.0009 0.0032 0.0005 0.0008 0.0005 0.0023 0.0005 0.0029 0.0004 0.0007 0.0005 0.0063 0.0027
Lipid Particles 0.0044 0.0024 0.0043 0.003 0.0052 0.004 0.009 0.0012 0.0011 0.0009 0.0026 0.0014 0.006 0.002 0.003 0.0017 0.0084 0.0045
Mitochondria 0.0016 0.0016 0.0016 0.0022 0.027 0.0021 0.0022 0.0013 0.0012 0.0012 0.0023 0.0012 0.002 0.0007 0.0021 0.0011 0.0024 0.0017
None 0.1218 0.1505 0.1485 0.1348 0.1014 0.125 0.03 0.0351 0.0484 0.0139 0.0071 0.0345 0.0497 0.0557 0.0935 0.1262 0.0346 0.0416
Nuclear Periphery 0.2455 0.1651 0.1945 0.2001 0.1733 0.1495 0.3444 0.2122 0.2814 0.3084 0.2923 0.2894 0.3188 0.1847 0.1838 0.1011 0.1457 0.1677
Nucleolus 0.0006 0.0009 0.001 0.0009 0.0008 0.001 0.0009 0.0022 0.0017 0.0004 0.0016 0.0008 0.0008 0.0008 0.0098 0.0011 0.0011 0.0009
Nucleus 0.0736 0.0714 0.0595 0.064 0.0756 0.0738 0.1118 0.124 0.1313 0.0886 0.1663 0.1307 0.0897 0.0623 0.0746 0.0764 0.0974 0.1035
Peroxisomes 0.0006 0.0002 0.0006 0.0003 0.0015 0.0006 0.0032 0.0001 0.0004 0.0002 0.0005 0.0002 0.0026 0.0001 0.0003 0.0003 0.0087 0.0015
Punctate Nuclear 0.0061 0.0121 0.0168 0.0136 0.0101 0.0205 0.0152 0.0246 0.0365 0.0212 0.0153 0.024 0.0136 0.0074 0.0191 0.0372 0.0124 0.0288
Vacuole 0.008 0.0122 0.0089 0.0084 0.007 0.0074 0.007 0.0089 0.0055 0.0054 0.0098 0.0053 0.0078 0.0108 0.0071 0.0051 0.0048 0.0068
Vacuole Periphery 0.0038 0.004 0.0038 0.0036 0.0031 0.0028 0.004 0.0027 0.0034 0.0039 0.0034 0.0029 0.0044 0.0027 0.0031 0.0017 0.0019 0.0024

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.6248 15.0477 17.3074 22.1174 11.458 15.9825 15.5951 24.1319 30.6876 22.06
Translational Efficiency 2.5146 1.7472 1.5834 1.7804 2.8911 2.1775 1.7528 1.5522 1.437 1.653

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1838 1881 2400 612 2002 1980 118 1552 3840 3861 2518 2164

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 661.82 910.34 844.26 1025.95 758.44 802.07 1000.59 1049.39 712.19 854.82 851.59 1042.76
Standard Deviation 83.15 582.52 116.49 147.34 98.94 105.93 132.19 146.13 103.65 417.13 121.84 146.86
Intensity Change Log 2 — 0.459967 0.351248 0.632450 — 0.080693 0.399744 0.468444 — 0.269873 0.377348 0.547193

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000104 0.000415 0.000131 0.002601 0.000075 0.000253 0.000876 0.002394 0.000088 0.000332 0.000166 0.002452
Bud Neck 0.002691 0.008188 0.006533 0.006552 0.001462 0.003409 0.003196 0.010320 0.002050 0.005738 0.006377 0.009254
Bud Site 0.000709 0.037102 0.005350 0.018772 0.001194 0.003443 0.002689 0.023201 0.000962 0.019841 0.005225 0.021948
Cell Periphery 0.000146 0.001348 0.000603 0.000559 0.000176 0.000152 0.000345 0.000600 0.000162 0.000734 0.000591 0.000588
Cytoplasm 0.199482 0.220177 0.325689 0.188028 0.211865 0.184778 0.163383 0.249645 0.205938 0.202024 0.318082 0.232219
Cytoplasmic Foci 0.092118 0.060958 0.036261 0.049869 0.056127 0.066437 0.036408 0.050094 0.073354 0.063768 0.036268 0.050030
Eisosomes 0.000104 0.000110 0.000509 0.000251 0.000092 0.000070 0.000127 0.000208 0.000098 0.000089 0.000491 0.000220
Endoplasmic Reticulum 0.218724 0.338516 0.041988 0.248962 0.324693 0.275093 0.130100 0.200863 0.273971 0.305991 0.046117 0.214466
Endosome 0.011824 0.016489 0.008040 0.024494 0.008764 0.018359 0.014196 0.024477 0.010228 0.017448 0.008328 0.024482
Golgi 0.006743 0.005771 0.000327 0.001394 0.004892 0.006446 0.000439 0.003162 0.005778 0.006117 0.000332 0.002662
Lipid Particles 0.173624 0.079464 0.022178 0.060305 0.123907 0.131664 0.036711 0.061682 0.147704 0.106233 0.022859 0.061293
Mitochondria 0.014073 0.012430 0.002519 0.000608 0.007793 0.014372 0.000572 0.002087 0.010799 0.013426 0.002428 0.001669
Mitotic Spindle 0.001089 0.007993 0.003991 0.011082 0.001879 0.009406 0.001907 0.036681 0.001501 0.008718 0.003893 0.029441
None 0.005171 0.004692 0.009454 0.000420 0.003810 0.003919 0.001207 0.001367 0.004461 0.004296 0.009068 0.001099
Nuclear Periphery 0.090800 0.060778 0.133848 0.018077 0.099263 0.109662 0.119270 0.021456 0.095212 0.085847 0.133165 0.020500
Nuclear Periphery Foci 0.074188 0.036654 0.054609 0.125567 0.080429 0.076223 0.252146 0.117403 0.077442 0.056946 0.063866 0.119712
Nucleolus 0.002574 0.001867 0.003115 0.000234 0.000915 0.002447 0.001530 0.000563 0.001709 0.002165 0.003041 0.000470
Nucleus 0.080027 0.060300 0.313158 0.046140 0.056186 0.055650 0.151468 0.062657 0.067597 0.057915 0.305581 0.057986
Peroxisomes 0.003130 0.002124 0.001242 0.001511 0.001589 0.002592 0.001441 0.001592 0.002327 0.002364 0.001251 0.001569
Vacuole 0.020533 0.040007 0.029908 0.193867 0.013225 0.031492 0.081600 0.128516 0.016723 0.035641 0.032330 0.146998
Vacuole Periphery 0.002146 0.004616 0.000547 0.000706 0.001663 0.004132 0.000388 0.001032 0.001894 0.004368 0.000540 0.000940

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.15 -2.03 -6.39 -5.55 -6.30 -2.39 -2.13 -7.43 -6.70 -3.16 -5.39 -3.72 -9.48 -8.38 -9.11
Bud Neck -6.57 -5.88 -6.67 0.77 -0.97 -3.32 -1.55 -12.30 -8.61 -5.08 -7.27 -7.48 -13.45 -5.92 -4.46
Bud Site -11.55 -5.31 -5.75 4.00 -4.11 -2.77 -2.03 -10.38 -9.09 -9.03 -11.70 -5.00 -11.99 -1.09 -8.68
Cell Periphery -4.04 -6.61 -9.94 2.66 0.43 1.87 -2.88 -6.19 -6.59 -1.98 -3.94 -6.54 -8.65 1.18 0.24
Cytoplasm -2.88 -16.14 1.41 3.49 13.16 3.66 2.04 -4.17 -7.46 -3.60 0.63 -16.74 -3.59 -4.12 11.31
Cytoplasmic Foci 7.63 15.08 8.83 2.35 -3.79 -3.11 2.36 1.52 4.78 -1.67 3.51 14.23 8.34 5.13 -6.01
Eisosomes -0.50 -2.35 -5.34 -4.87 1.46 2.93 -2.39 -7.52 -9.63 -2.15 1.28 -2.40 -9.23 -9.54 1.66
Endoplasmic Reticulum -12.51 27.98 1.01 10.00 -14.83 5.37 12.64 16.84 11.50 -3.18 -4.58 45.29 13.14 16.95 -23.10
Endosome -5.23 4.78 -6.23 -3.45 -8.21 -10.31 -3.37 -13.05 -3.76 -3.68 -11.17 2.70 -13.62 -5.49 -14.19
Golgi 1.25 10.13 8.52 7.95 -4.62 -1.96 9.18 3.07 4.46 -3.56 -0.52 13.91 6.27 6.55 -4.33
Lipid Particles 17.24 32.11 20.11 4.85 -9.16 -1.42 15.55 14.59 15.61 -4.56 10.84 40.14 24.79 14.62 -14.88
Mitochondria 1.26 11.16 13.35 13.29 7.41 -4.34 7.81 6.02 9.99 -3.81 -2.56 11.62 12.83 15.05 2.72
Mitotic Spindle -5.11 -3.80 -4.47 -1.84 -3.16 -4.70 -0.52 -10.28 -7.61 -8.48 -6.87 -3.28 -11.23 -7.99 -9.73
None 0.63 -3.43 9.17 6.54 8.26 0.00 3.94 4.63 4.13 0.13 0.43 -4.03 8.40 6.77 7.57
Nuclear Periphery 6.34 -6.68 18.37 12.71 22.32 -1.84 -0.40 19.97 21.19 5.10 2.61 -6.48 26.92 24.04 23.10
Nuclear Periphery Foci 9.80 4.27 -5.98 -11.82 -8.69 1.00 -6.26 -5.86 -6.73 4.94 6.87 3.48 -8.47 -13.82 -10.46
Nucleolus 2.50 -1.69 9.39 8.23 8.40 -2.95 -1.27 2.22 3.73 1.66 -1.35 -4.09 8.42 6.04 7.84
Nucleus 5.45 -37.96 7.20 2.88 41.35 0.04 -4.99 -2.25 -2.23 4.61 4.06 -42.58 3.15 -0.42 43.29
Peroxisomes 3.31 6.83 4.78 2.06 -0.32 -3.02 0.05 0.24 3.02 0.05 -0.12 5.68 4.45 3.69 -1.02
Vacuole -9.06 -6.67 -21.86 -19.69 -20.54 -10.02 -5.89 -29.04 -24.61 -3.78 -13.45 -11.05 -35.59 -30.86 -30.13
Vacuole Periphery -4.18 11.03 7.78 6.77 -0.40 -7.11 7.39 3.50 9.65 -3.36 -7.30 11.43 6.97 10.49 -2.28
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p; UBX7 has a paralog, UBX6, that arose from the whole genome duplication
Localization
Cell Percentages ER (74%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Ubx7

Ubx7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ubx7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available