Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.05 0
Bud 0 0 0.07 0.05 0.07 0 – 0 0 0 0 0 0 0 0 0 0.11 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.08 0.06 0.12 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0 – 0 0 0 0 0 0 0 0 0.06 0.1 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0.08 0.06 0.11 0.08 0.11 0.05 0 0.08 0 0 0
Golgi 0.05 0.12 0 0 0 0 – 0 0 0 0 0 0.15 0.13 0.27 0.3 0.29 0.24 0.07 0.11 0 0.11 0.12 0.14
Mitochondria 0.91 0.82 0.95 0.96 0.92 0.92 – 0.94 0.96 0.96 0.96 0.94 0.89 0.79 0.74 0.1 0.05 0.1 0.77 0.73 0.77 0.66 0.61 0.66
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.09 – 0.09 0.11 0.07 0.07 0.09 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.05 – 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0.07 0.17 0.1 0.1 0.11 0.08 0 0 0.05 0.09 0.11 0.07
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0.06 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0.14 0.17 0.05 0 0.06 0 – 0 0 0 0 0 0.07 0.08 0.09 0.16 0.14 0.16 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 5 3 1 0 0 – 0 0 1 3 0 2 0 1 4 7 7 16 17 3 10 24 17
Bud 14 3 35 19 27 11 – 29 14 23 18 20 15 5 3 7 16 9 1 3 0 2 1 1
Bud Neck 0 0 1 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1
Bud Site 1 0 2 2 8 3 – 6 7 4 8 7 2 1 0 1 2 1 – – – – – –
Cell Periphery 24 35 13 15 5 5 – 3 5 9 1 15 14 19 32 13 8 25 0 1 0 0 1 0
Cytoplasm 5 6 11 13 24 23 – 29 16 17 8 14 7 10 18 9 15 26 0 3 1 0 1 0
Endoplasmic Reticulum 6 5 7 5 5 5 – 6 5 10 7 9 5 1 3 4 5 10 1 3 0 0 4 3
Endosome 12 8 1 0 0 5 – 3 0 3 0 0 9 43 34 18 11 24 41 17 42 18 20 16
Golgi 36 67 1 1 0 1 – 2 0 0 0 1 72 71 155 48 42 50 53 64 12 44 57 66
Mitochondria 697 442 483 381 378 578 – 908 696 770 492 507 425 423 428 16 7 21 614 448 390 266 295 321
Nucleus 2 5 7 1 7 4 – 4 3 2 2 2 3 1 1 5 6 6 0 0 0 1 0 0
Nuclear Periphery 25 18 19 17 9 56 – 92 79 57 38 51 19 9 2 8 4 10 6 3 2 6 1 3
Nucleolus 20 7 10 7 14 33 – 65 36 36 22 19 8 5 2 6 4 4 3 2 0 1 3 1
Peroxisomes 6 12 2 4 1 1 – 8 2 5 0 5 35 90 56 16 16 18 17 19 27 36 54 35
SpindlePole 1 3 7 0 4 2 – 14 5 6 1 3 2 6 11 8 8 18 3 1 4 3 2 1
Vac/Vac Membrane 108 91 25 7 24 25 – 26 31 26 15 13 33 43 52 25 21 34 35 21 8 11 10 10
Unique Cell Count 762 539 506 397 410 627 971 725 804 515 537 478 534 582 158 145 212 801 611 505 407 484 484
Labelled Cell Count 964 707 627 473 506 752 1195 899 969 615 666 651 727 798 188 172 263 801 611 505 407 484 484


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 8.7 4.6 5.3 3.9 5.5 – 5.5 5.1 5.6 5.4 5.4 7.7 8.5 8.2 8.5 8.2 7.8 8.4 8.9 9.2
Std Deviation (1e-4) 1.2 1.4 1.0 1.2 1.0 1.4 – 1.3 1.3 1.3 1.4 1.4 1.8 1.5 1.6 1.8 2.0 1.8 1.5 1.7 1.8
Intensity Change (Log2) – – – 0.21 -0.22 0.25 – 0.26 0.14 0.29 0.24 0.23 0.75 0.88 0.84 0.88 0.83 0.76 0.87 0.96 1.0

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud -1.3 0 -4.4 – -3.5 -4.4 -3.5 -2.5 -2.3 -2.7 -5.0 -5.7 -1.1 1.6 -1.4
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.0 0 -2.4 – -4.0 -2.7 -2.0 -3.3 0.2 0.3 0.9 2.4 3.2 0 5.0
Cytoplasm 1.0 2.9 1.5 – 0.9 0 -0.1 -0.7 0.5 -0.8 -0.3 0.9 0 4.4 5.6
Endoplasmic Reticulum -0.2 0 -1.0 – 0 0 -0.2 0 0.4 -0.5 0 0 0 0 2.7
Endosome 0 0 0 – 0 0 0 0 0 0 6.3 5.3 0 0 7.4
Golgi 0 0 0 – 0 0 0 0 0 8.9 8.3 12.4 12.7 12.3 11.1
Mitochondria 0.4 0 -2.2 – -1.5 0.5 0.3 0.1 -0.8 -3.8 -7.8 -9.8 -21.7 -22.3 -22.9
Nucleus 0 0.4 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.4 0 3.5 – 4.0 4.6 2.5 2.5 3.7 0.2 -2.1 -4.1 0.7 -0.6 0.6
Nucleolus -0.2 0 2.9 – 3.9 2.7 2.4 2.1 1.5 -0.4 -1.4 -2.6 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 5.7 9.3 6.8 0 0 6.0
SpindlePole 0 0 0 – 0.1 0 -1.1 0 0 0 -0.4 0.7 0 0 4.7
Vacuole -2.6 0.6 -0.8 – -2.3 -0.6 -1.6 -1.7 -2.2 1.3 2.0 2.6 4.5 4.0 4.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.1952 6.6718 5.9825 5.805 6.2112 6.5348 5.1158 5.0637 5.0368 4.3002 4.778 5.0428 7.7895 7.1941 7.6292 7.5697 7.2013 7.3001
Actin 0.024 0.0064 0.0159 0.0174 0.0003 0.0092 0.008 0.0043 0.0056 0.001 0.0154 0.0029 0.0039 0.0025 0.0013 0.0005 0.0016 0.0012
Bud 0.0008 0.0003 0.0012 0.0002 0 0.0001 0.0002 0.0002 0.0001 0 0.0003 0 0.0003 0.0003 0.0003 0.0003 0.0032 0
Bud Neck 0.0038 0.0001 0.0003 0.0004 0 0.0001 0.0002 0.0001 0.0001 0 0.0005 0.0001 0.0002 0.0001 0.0001 0 0 0
Bud Periphery 0.0016 0.0006 0.0017 0.0004 0.0001 0.0002 0.0009 0.0003 0.0002 0.0001 0.0008 0.0001 0.0008 0.0006 0.0011 0.0022 0.0216 0.0001
Bud Site 0.0058 0.0005 0.0108 0.0011 0 0.0001 0.0004 0.0003 0.0005 0.0001 0.0003 0.0001 0.0005 0.0014 0.0005 0.0001 0.0002 0
Cell Periphery 0.0007 0.0003 0.0004 0.0001 0 0.0001 0.0003 0.0001 0.0001 0 0.0002 0 0.0004 0.0004 0.0002 0.0002 0.0005 0
Cytoplasm 0.0026 0.0001 0.001 0.0003 0 0 0.0003 0.0001 0 0 0.0002 0 0.0003 0.0001 0.0001 0 0.0001 0
Cytoplasmic Foci 0.0139 0.0016 0.0089 0.0109 0.0031 0.002 0.008 0.0025 0.0017 0.0007 0.0056 0.0012 0.0027 0.005 0.0017 0.0009 0.001 0.0007
Eisosomes 0.0004 0.0002 0.0002 0.0002 0.0001 0.0001 0.0003 0.0002 0.0002 0.0002 0.0003 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0001
Endoplasmic Reticulum 0.0014 0.0001 0.0005 0.0002 0 0.0002 0.0003 0 0.0001 0 0.0005 0.0001 0.0007 0.0001 0.0001 0 0.0001 0.0001
Endosome 0.0207 0.0135 0.018 0.0245 0.0212 0.007 0.0173 0.0098 0.0034 0.0011 0.0387 0.0035 0.0118 0.0101 0.007 0.0041 0.0053 0.0066
Golgi 0.0314 0.0136 0.0193 0.0297 0.0269 0.0152 0.0226 0.0201 0.0094 0.0064 0.0495 0.011 0.0154 0.0173 0.0117 0.0188 0.012 0.0209
Lipid Particles 0.0385 0.0123 0.0077 0.019 0.0017 0.0118 0.0166 0.0059 0.0061 0.0011 0.0318 0.0047 0.0156 0.0108 0.0026 0.0018 0.0015 0.0032
Mitochondria 0.8095 0.9212 0.8861 0.8768 0.9413 0.9378 0.9017 0.9454 0.9565 0.9852 0.8252 0.9649 0.9312 0.9286 0.961 0.9635 0.9367 0.9632
None 0.0006 0 0.0002 0.0002 0 0.0001 0.0005 0 0 0 0.0002 0 0.0006 0 0 0.0001 0.0001 0
Nuclear Periphery 0.011 0.0001 0.0003 0.0002 0 0.0004 0.0026 0 0.0002 0 0.0007 0.0001 0.0016 0.0001 0 0 0.0001 0
Nucleolus 0.0032 0.0003 0.0004 0.0001 0 0.0001 0.0006 0.0001 0 0 0.0002 0 0.0002 0.0002 0.0001 0 0 0
Nucleus 0.0041 0.0002 0.0009 0.0001 0 0.0001 0.0005 0 0 0 0.0002 0 0.0004 0.0001 0.0001 0 0 0
Peroxisomes 0.0102 0.0053 0.0103 0.0136 0.0026 0.0118 0.0133 0.0085 0.0133 0.0033 0.0037 0.0097 0.0058 0.0164 0.0088 0.0053 0.0093 0.0016
Punctate Nuclear 0.0028 0 0.0003 0.0007 0 0.0005 0.0004 0 0 0 0.0003 0.0001 0.0005 0 0 0 0 0
Vacuole 0.0078 0.014 0.0057 0.0012 0.0006 0.0007 0.0019 0.0007 0.0004 0.0001 0.0122 0.0003 0.0027 0.0023 0.002 0.0007 0.0013 0.0004
Vacuole Periphery 0.0053 0.0093 0.0099 0.0026 0.002 0.0024 0.003 0.0014 0.0019 0.0005 0.0133 0.001 0.0042 0.0033 0.0013 0.0012 0.0053 0.0017

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.7654 15.6568 13.2777 28.9975 19.4641 17.5047 28.2688 37.3959 25.0976 36.7139
Translational Efficiency 3.4958 3.4937 3.7989 1.5333 3.0464 3.9873 2.3282 1.5999 2.5514 1.8681

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1071 1380 68 222 1857 1862 1248 1233 2928 3242 1316 1455

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 823.57 900.60 1152.33 1208.51 729.86 895.42 1039.75 1075.74 764.14 897.62 1045.57 1096.00
Standard Deviation 136.21 157.58 158.20 160.71 129.61 146.11 156.76 164.13 139.56 151.12 158.80 170.43
Intensity Change Log 2 — 0.128995 0.484591 0.553266 — 0.294945 0.510545 0.559638 — 0.209346 0.496843 0.556263

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002059 0.001637 0.002491 0.012736 0.002148 0.004807 0.005374 0.010763 0.002115 0.003458 0.005225 0.011064
Bud Neck 0.002407 0.000758 0.008095 0.002659 0.001201 0.000674 0.003758 0.002265 0.001642 0.000710 0.003982 0.002325
Bud Site 0.003955 0.001651 0.004277 0.008996 0.001953 0.001596 0.012555 0.012980 0.002685 0.001620 0.012127 0.012372
Cell Periphery 0.000591 0.000193 0.000244 0.000408 0.000585 0.000329 0.000263 0.000475 0.000587 0.000271 0.000262 0.000465
Cytoplasm 0.001166 0.000478 0.001278 0.001027 0.000346 0.000410 0.001687 0.001477 0.000646 0.000439 0.001666 0.001408
Cytoplasmic Foci 0.023699 0.021925 0.093262 0.036475 0.005964 0.012345 0.018539 0.015238 0.012451 0.016423 0.022400 0.018478
Eisosomes 0.000056 0.000049 0.000083 0.000133 0.000048 0.000067 0.000063 0.000112 0.000051 0.000059 0.000064 0.000116
Endoplasmic Reticulum 0.000341 0.000153 0.003297 0.001411 0.000195 0.000168 0.000360 0.000485 0.000248 0.000162 0.000512 0.000627
Endosome 0.049904 0.032970 0.086296 0.031783 0.011432 0.023271 0.033145 0.020772 0.025504 0.027400 0.035891 0.022452
Golgi 0.036124 0.036622 0.067819 0.108725 0.013226 0.023788 0.030817 0.046666 0.021601 0.029251 0.032729 0.056135
Lipid Particles 0.007821 0.003078 0.017434 0.002094 0.002561 0.001800 0.002517 0.000887 0.004485 0.002344 0.003287 0.001071
Mitochondria 0.820461 0.869006 0.523152 0.678692 0.940881 0.902721 0.820241 0.841577 0.896834 0.888370 0.804890 0.816724
Mitotic Spindle 0.005384 0.002803 0.090993 0.034975 0.001041 0.002093 0.026397 0.008732 0.002629 0.002395 0.029735 0.012736
None 0.000271 0.000209 0.000809 0.000505 0.000201 0.000151 0.000323 0.000278 0.000226 0.000176 0.000348 0.000313
Nuclear Periphery 0.000250 0.000138 0.011870 0.001144 0.000059 0.000053 0.000404 0.000345 0.000129 0.000089 0.000996 0.000467
Nuclear Periphery Foci 0.000479 0.000179 0.011112 0.000913 0.000094 0.000076 0.000411 0.000324 0.000235 0.000120 0.000964 0.000414
Nucleolus 0.000682 0.000086 0.001472 0.000188 0.000213 0.000039 0.000515 0.000044 0.000385 0.000059 0.000564 0.000066
Nucleus 0.000837 0.000064 0.002342 0.000101 0.000798 0.000050 0.000322 0.000112 0.000813 0.000056 0.000426 0.000110
Peroxisomes 0.025812 0.015900 0.038335 0.037818 0.013348 0.019966 0.021434 0.021707 0.017907 0.018236 0.022308 0.024165
Vacuole 0.006032 0.005624 0.018871 0.018178 0.001197 0.002580 0.012080 0.007859 0.002966 0.003876 0.012431 0.009434
Vacuole Periphery 0.011669 0.006474 0.016467 0.021037 0.002510 0.003015 0.008796 0.006901 0.005860 0.004487 0.009192 0.009058

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.68 -0.58 -3.40 -3.55 -3.25 -2.84 -2.42 -4.79 -3.03 -2.46 -2.24 -2.48 -5.62 -4.60 -2.93
Bud Neck 2.16 -2.97 -0.29 -4.08 2.99 1.48 -4.63 -2.13 -4.00 2.56 2.60 -4.25 -1.45 -4.78 3.06
Bud Site 2.42 -0.27 -1.62 -2.45 -1.52 0.65 -6.02 -5.43 -5.60 -0.13 2.20 -5.62 -5.39 -6.08 -0.07
Cell Periphery 1.80 1.57 0.74 -1.81 -1.38 1.34 2.29 0.74 -0.94 -2.46 2.24 2.61 0.93 -1.89 -2.60
Cytoplasm 0.98 -0.14 0.19 -3.12 0.69 -0.56 -4.58 -5.40 -5.20 0.53 0.78 -2.82 -2.63 -5.61 0.75
Cytoplasmic Foci 0.73 -4.25 -2.26 -2.60 3.31 -5.38 -7.65 -6.58 -1.84 1.70 -3.28 -5.27 -3.86 -1.28 1.81
Eisosomes 1.52 -2.26 -5.17 -5.67 -2.74 -3.24 -3.04 -7.03 -4.59 -5.32 -2.13 -3.01 -8.10 -6.83 -6.18
Endoplasmic Reticulum 4.56 -1.33 -3.00 -3.54 0.84 0.59 -2.21 -3.56 -3.85 -1.38 2.77 -1.97 -4.33 -5.33 -0.84
Endosome 3.98 -2.66 3.30 0.25 3.95 -6.01 -8.06 -4.88 1.08 4.19 -0.93 -3.59 1.42 2.46 4.66
Golgi -0.14 -2.27 -5.51 -5.49 -2.18 -4.92 -6.07 -9.04 -5.95 -3.68 -3.90 -3.87 -9.06 -6.98 -5.34
Lipid Particles 3.33 -1.52 4.26 1.32 2.47 1.27 0.06 2.95 2.59 2.77 3.26 1.42 5.62 3.50 3.43
Mitochondria -4.52 6.33 5.50 7.58 -2.99 6.04 13.19 11.26 6.60 -1.85 1.46 9.85 9.09 8.23 -1.03
Mitotic Spindle 2.38 -3.76 -3.29 -3.60 2.30 -1.77 -9.89 -6.51 -5.21 6.34 0.41 -9.88 -5.80 -5.99 5.34
None 2.33 -1.16 -3.60 -4.85 0.65 1.66 -3.59 -2.42 -8.87 2.15 2.38 -3.41 -3.43 -8.84 1.13
Nuclear Periphery 1.66 -1.74 -2.50 -2.84 1.60 0.35 -4.74 -1.82 -1.87 0.35 1.43 -2.43 -2.33 -2.63 1.38
Nuclear Periphery Foci 1.99 -1.99 -1.65 -3.32 1.91 0.57 -4.92 -1.72 -1.88 0.61 1.94 -2.50 -1.39 -2.50 1.78
Nucleolus 1.62 -1.18 1.33 -1.15 2.41 1.32 -1.25 1.28 -0.42 2.36 2.05 -0.68 2.01 -0.39 2.60
Nucleus 1.42 -1.22 1.36 -1.36 2.25 1.56 0.96 1.29 -1.35 1.01 2.09 1.04 1.78 -1.39 1.81
Peroxisomes 2.84 -1.36 -1.31 -2.49 0.04 -2.61 -3.13 -2.88 -0.55 -0.07 -0.16 -1.77 -2.18 -2.11 -0.57
Vacuole 0.47 -3.32 -2.89 -2.98 0.12 -3.71 -8.21 -5.66 -4.45 2.14 -2.18 -7.38 -5.46 -4.63 1.53
Vacuole Periphery 4.08 -1.57 -1.81 -2.85 -0.79 -1.12 -5.94 -4.96 -4.41 1.46 2.44 -3.11 -2.79 -4.17 0.10
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrpl27

Mrpl27


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrpl27-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available