Standard name
Human Ortholog
Description Vacuolar aminopeptidase Y; processed to mature form by Prb1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.94 0.97 0.98 0.97 0.93 0.91 0.89 0.93 0.9 0.89 0.85 0.89 0.98 0.96 0.98 0.89 0.89 0.89 0.53 0.82 0.62 0.65 0.67 0.69
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.09 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.1 0 0 0 0 0 0 0 0 0 0.16 0.05 0 0 0 0 0 0 0.13 0 0.11 0.05 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.15 0.13 0.23 0.1 0.13 0.16 0.11 0.11 0 0 0 0.13 0.11 0.11 0.21 0.1 0.18 0.21 0.2 0.19
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 2
Bud 1 0 0 0 0 0 2 0 0 4 1 0 2 0 1 0 2 0 0 0 0 0 0 3
Bud Neck 0 2 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 0 0 0 3
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 1 2 1 0 0 2 1 1 0 1 0 1 0 0 1 4 0 0 0 0 0 0
Cytoplasm 174 202 124 242 290 329 357 415 208 296 188 294 134 241 268 98 171 120 101 180 87 46 83 149
Endoplasmic Reticulum 1 1 0 2 0 0 0 1 0 0 0 2 0 1 0 5 18 9 4 0 2 0 1 0
Endosome 0 0 0 0 0 0 2 3 0 1 0 2 0 2 2 2 0 2 6 2 1 0 0 2
Golgi 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0
Mitochondria 19 3 0 0 0 3 2 5 5 5 35 17 0 2 0 3 4 1 25 8 15 3 4 4
Nucleus 0 0 1 1 0 8 11 10 10 2 5 4 2 0 1 0 2 1 0 0 0 0 1 1
Nuclear Periphery 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 0 0 0 0 1 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 1 0 0 2 0 1 0 1 1 1 0 0 0 0 1 0 0 0 0 1
Vac/Vac Membrane 5 3 1 2 46 48 93 46 30 54 24 36 0 2 0 14 21 15 41 21 25 15 24 41
Unique Cell Count 186 208 126 249 313 362 403 448 232 331 222 330 137 250 273 110 193 135 191 221 141 71 125 217
Labelled Cell Count 201 213 129 254 339 389 467 485 254 364 253 358 140 251 274 122 219 153 191 221 141 71 125 217


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 3.9 5.3 5.0 6.0 4.8 5.2 5.4 4.6 4.7 4.2 4.5 4.7 5.3 5.3 5.7 5.7 5.3 4.4 5.2 5.3
Std Deviation (1e-4) 0.5 0.5 2.1 1.7 2.0 1.2 1.2 1.8 1.3 1.1 1.2 1.4 1.1 1.5 2.1 1.6 1.6 1.1 1.0 2.0 1.7
Intensity Change (Log2) – – – -0.1 0.17 -0.13 -0.04 0.03 -0.22 -0.18 -0.35 -0.25 -0.17 -0.0 -0.02 0.1 0.1 0.01 -0.29 -0.03 0.01

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 3.7 3.5 3.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.8527 -0.5142 -0.6435 -0.1294 -0.5451 -0.4966 -1.8007 -0.9791 -0.9215 -1.3667 -0.9183 -1.2272 -1.1359 -1.0435 -1.2442 -0.3614 -0.9353 -1.2643
Actin 0.0175 0.002 0.0051 0.0469 0.0132 0.0067 0.0164 0.0001 0.0008 0.0001 0.0059 0.0021 0.0208 0.0001 0.0015 0.0063 0.0091 0.0084
Bud 0.0016 0.0062 0.002 0.0025 0.0019 0.0013 0.0018 0.0076 0.0064 0.0002 0.011 0.0001 0.0018 0.0009 0.0017 0.0014 0.0088 0.0003
Bud Neck 0.0051 0.0005 0.0047 0.0016 0.007 0.0066 0.0004 0.0005 0.0012 0.0001 0.0006 0.0004 0.0078 0.0007 0.0041 0.0044 0.003 0.0014
Bud Periphery 0.0051 0.0088 0.0051 0.0051 0.0055 0.0026 0.0016 0.0014 0.0144 0.0003 0.044 0.0003 0.004 0.0012 0.0052 0.0021 0.0145 0.0005
Bud Site 0.004 0.0107 0.0068 0.0037 0.0085 0.0014 0.0009 0.0137 0.01 0.0003 0.0026 0.0005 0.008 0.0138 0.0046 0.0079 0.0136 0.0005
Cell Periphery 0.0005 0.0004 0.0003 0.0002 0.0004 0.0002 0.0002 0.0006 0.0011 0.0001 0.0006 0.0002 0.0006 0.0005 0.0007 0.0011 0.0008 0.0002
Cytoplasm 0.1136 0.1056 0.0795 0.1503 0.1261 0.1546 0.0357 0.0474 0.0185 0.0483 0.0156 0.1259 0.1177 0.1696 0.1314 0.1068 0.0872 0.2518
Cytoplasmic Foci 0.0474 0.0224 0.0401 0.0795 0.0667 0.0424 0.0193 0.012 0.031 0.0344 0.0592 0.0223 0.054 0.0229 0.0236 0.0934 0.0449 0.0528
Eisosomes 0.0003 0.0002 0.0004 0.0002 0.0001 0.0001 0.0004 0.0001 0.0002 0.0001 0.0002 0.0001 0.0004 0.0002 0.0013 0.0003 0.0004 0.0001
Endoplasmic Reticulum 0.0029 0.0013 0.0021 0.0021 0.0014 0.0018 0.0015 0.001 0.0012 0.0005 0.0007 0.0017 0.0048 0.0028 0.0018 0.0019 0.0064 0.0021
Endosome 0.0547 0.0194 0.0404 0.0825 0.0665 0.0398 0.0155 0.012 0.0544 0.0363 0.0563 0.01 0.0437 0.0332 0.0344 0.0825 0.0963 0.0381
Golgi 0.0043 0.0007 0.0019 0.009 0.0075 0.0019 0.002 0.0003 0.004 0.0006 0.0118 0.0015 0.0084 0.0005 0.0012 0.01 0.0138 0.0029
Lipid Particles 0.0094 0.0011 0.0047 0.0044 0.0193 0.0095 0.0054 0.0028 0.0127 0.0018 0.0046 0.0063 0.028 0.003 0.0084 0.0182 0.0273 0.0144
Mitochondria 0.0093 0.0017 0.0034 0.0089 0.0129 0.0038 0.0027 0.0008 0.0103 0.003 0.1669 0.0044 0.0148 0.001 0.0028 0.0222 0.0113 0.0036
None 0.6702 0.7798 0.7515 0.5097 0.5125 0.6681 0.8745 0.8698 0.7366 0.8503 0.5828 0.802 0.5765 0.6884 0.7026 0.5477 0.5199 0.5693
Nuclear Periphery 0.0031 0.001 0.005 0.0018 0.0022 0.0021 0.0013 0.0005 0.002 0.0006 0.0009 0.0022 0.0099 0.0011 0.0016 0.0021 0.0095 0.0012
Nucleolus 0.0024 0.0022 0.0018 0.0024 0.0028 0.0011 0.0011 0.0032 0.0033 0.0004 0.0008 0.0006 0.0027 0.001 0.0032 0.0051 0.0027 0.0009
Nucleus 0.0046 0.0048 0.0097 0.0055 0.0063 0.0041 0.0015 0.0031 0.0043 0.0011 0.0009 0.0054 0.0052 0.0026 0.0047 0.0051 0.0087 0.0023
Peroxisomes 0.0053 0.001 0.0059 0.0079 0.0203 0.0068 0.0011 0.0002 0.0047 0.0007 0.004 0.0016 0.0345 0.0007 0.0018 0.0172 0.0098 0.0081
Punctate Nuclear 0.0041 0.0071 0.0091 0.0024 0.0043 0.0042 0.0011 0.0017 0.0141 0.0007 0.0018 0.0013 0.0074 0.0008 0.0065 0.0044 0.0221 0.0047
Vacuole 0.0317 0.0215 0.0183 0.0664 0.1054 0.0376 0.0146 0.0203 0.0527 0.0167 0.0205 0.0104 0.0447 0.0521 0.0523 0.0543 0.0788 0.0326
Vacuole Periphery 0.003 0.0015 0.0021 0.0069 0.0091 0.0034 0.001 0.0008 0.016 0.0033 0.0084 0.0008 0.0042 0.0029 0.0046 0.0053 0.0111 0.0039

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 496.3269 479.1319 557.7933 587.5701 526.5078 484.4366 563.2347 584.7108 566.8887 529.8523
Translational Efficiency 1.4711 1.4262 1.3267 1.1873 1.1774 1.6165 1.3513 1.201 1.3094 1.3247

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
960 1102 1259 393 848 1982 79 785 1808 3084 1338 1178

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 566.37 684.54 867.66 818.69 711.36 679.82 929.83 778.94 634.37 681.51 871.33 792.20
Standard Deviation 60.56 86.23 100.76 118.94 81.12 82.45 110.59 110.31 101.34 83.85 102.42 114.80
Intensity Change Log 2 — 0.273390 0.615385 0.531572 — -0.065427 0.386387 0.130932 — 0.094641 0.492401 0.322350

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000158 0.000234 0.000414 0.000200 0.000302 0.000128 0.000313 0.001155 0.000226 0.000166 0.000408 0.000837
Bud Neck 0.042017 0.022615 0.010066 0.004403 0.008718 0.039354 0.007064 0.012378 0.026399 0.033373 0.009889 0.009718
Bud Site 0.005336 0.009840 0.011707 0.005855 0.002966 0.013567 0.008583 0.038031 0.004225 0.012235 0.011522 0.027297
Cell Periphery 0.000201 0.000323 0.000145 0.000186 0.000163 0.000102 0.000227 0.000226 0.000184 0.000181 0.000150 0.000213
Cytoplasm 0.405532 0.443131 0.402844 0.455235 0.528022 0.376260 0.245341 0.484662 0.462983 0.400155 0.393544 0.474845
Cytoplasmic Foci 0.278069 0.238970 0.021867 0.035750 0.197657 0.236388 0.026160 0.030612 0.240353 0.237311 0.022121 0.032326
Eisosomes 0.000423 0.000109 0.000046 0.000068 0.000144 0.000109 0.000111 0.000062 0.000293 0.000109 0.000050 0.000064
Endoplasmic Reticulum 0.000698 0.000621 0.005291 0.001525 0.000665 0.000597 0.005216 0.002158 0.000682 0.000606 0.005287 0.001947
Endosome 0.032196 0.027645 0.008914 0.009607 0.010764 0.040034 0.007116 0.008955 0.022144 0.035607 0.008807 0.009173
Golgi 0.003157 0.003301 0.000275 0.016293 0.001255 0.004526 0.000090 0.002799 0.002265 0.004089 0.000264 0.007301
Lipid Particles 0.017637 0.006963 0.002801 0.002064 0.006341 0.007753 0.003865 0.001498 0.012339 0.007470 0.002864 0.001687
Mitochondria 0.005764 0.009042 0.000768 0.003039 0.002519 0.014945 0.000327 0.006660 0.004242 0.012836 0.000742 0.005452
Mitotic Spindle 0.000288 0.002682 0.012678 0.021820 0.006641 0.009731 0.005686 0.013056 0.003268 0.007212 0.012266 0.015980
None 0.004706 0.004169 0.003388 0.009706 0.003214 0.002408 0.003137 0.004967 0.004006 0.003037 0.003373 0.006548
Nuclear Periphery 0.000435 0.000589 0.003157 0.001352 0.000556 0.000556 0.002005 0.001301 0.000492 0.000568 0.003089 0.001318
Nuclear Periphery Foci 0.000372 0.000438 0.005475 0.001324 0.000395 0.000339 0.003089 0.001745 0.000383 0.000375 0.005334 0.001605
Nucleolus 0.001685 0.002345 0.001451 0.000891 0.000886 0.002262 0.000570 0.000655 0.001310 0.002292 0.001399 0.000734
Nucleus 0.109243 0.123509 0.425732 0.239179 0.176761 0.106447 0.460103 0.237070 0.140911 0.112543 0.427762 0.237774
Peroxisomes 0.009446 0.014976 0.001698 0.000371 0.005317 0.012094 0.000352 0.002120 0.007510 0.013123 0.001619 0.001536
Vacuole 0.081383 0.085564 0.080934 0.187174 0.045933 0.128607 0.220197 0.148067 0.064756 0.113226 0.089156 0.161114
Vacuole Periphery 0.001250 0.002935 0.000350 0.003956 0.000779 0.003793 0.000447 0.001821 0.001029 0.003486 0.000355 0.002533

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.29 -6.18 -0.86 0.74 6.31 1.05 -0.36 -1.51 -3.33 -1.72 0.71 -3.20 -2.06 -3.12 0.20
Bud Neck 5.35 8.68 11.84 9.29 4.64 -13.84 0.18 0.07 12.33 -0.14 -3.15 6.44 9.31 14.77 2.52
Bud Site -3.15 -3.24 0.09 2.93 3.08 -7.92 -1.55 -5.64 -2.15 -2.55 -7.90 -4.16 -5.28 -1.47 -1.85
Cell Periphery -0.78 3.18 2.90 1.21 0.79 4.15 -1.29 0.41 -2.94 1.52 0.17 2.25 2.04 0.48 0.43
Cytoplasm -2.95 4.90 2.61 4.61 -0.58 13.82 13.85 9.85 -1.25 -7.79 7.91 12.62 7.66 1.79 -3.45
Cytoplasmic Foci 4.45 37.86 35.49 31.55 -1.35 -4.76 22.91 26.45 41.33 -0.93 0.66 44.51 43.95 52.02 -1.20
Eisosomes 10.88 12.83 11.77 3.98 -5.51 3.78 1.32 7.68 8.06 3.95 11.31 14.30 13.37 8.90 -4.30
Endoplasmic Reticulum 0.55 -18.98 -7.27 -8.20 12.55 0.41 -6.24 -9.45 -11.50 3.56 0.71 -19.97 -12.12 -13.87 12.02
Endosome 1.65 9.57 10.86 10.38 2.55 -14.14 2.61 4.25 18.45 1.27 -7.25 8.23 11.75 21.11 3.56
Golgi -0.09 4.93 -0.96 -0.93 -1.86 -6.33 3.78 0.28 5.26 -2.03 -3.64 5.80 -0.48 1.02 -2.28
Lipid Particles 6.29 8.84 9.64 9.34 4.67 -1.53 2.69 6.19 11.37 3.77 4.85 9.50 11.21 14.51 6.36
Mitochondria -1.97 5.49 3.02 4.39 -0.71 -7.35 2.05 -0.24 7.30 -2.51 -7.21 4.91 1.76 8.45 -2.11
Mitotic Spindle -3.16 -6.58 -2.63 -1.91 1.58 -1.07 0.39 -0.63 0.55 -0.83 -2.65 -4.99 -2.91 -0.96 2.61
None 0.48 1.55 -0.90 -1.63 -2.91 1.51 0.30 -1.71 -3.28 -1.55 1.50 1.50 -1.13 -3.38 -3.64
Nuclear Periphery -1.96 -16.91 -9.73 -8.32 9.17 -0.05 -8.68 -8.43 -9.98 1.13 -1.08 -16.88 -12.41 -12.53 8.57
Nuclear Periphery Foci -1.52 -8.18 -5.05 -4.56 6.49 0.57 -4.56 -6.29 -6.11 2.37 0.05 -8.46 -7.73 -7.32 6.10
Nucleolus -2.12 -1.43 5.03 5.58 4.65 -6.18 2.17 2.41 7.50 -0.12 -5.06 -2.51 5.54 9.33 4.90
Nucleus -2.40 -35.48 -11.33 -9.89 12.51 10.16 -6.75 -7.63 -16.32 4.33 6.28 -32.87 -14.46 -19.00 16.05
Peroxisomes -3.25 7.93 10.54 9.69 4.06 -4.86 4.66 3.82 11.94 -2.21 -5.46 7.34 9.33 15.28 2.35
Vacuole -1.55 -6.28 -14.91 -14.40 -12.31 -18.42 -7.70 -21.04 -12.52 1.32 -13.82 -11.78 -24.70 -18.69 -15.35
Vacuole Periphery -3.93 7.56 -0.32 0.98 -1.10 -7.63 2.03 -0.02 6.14 -1.15 -8.44 6.67 -0.08 4.53 -1.60
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Vacuolar aminopeptidase Y; processed to mature form by Prb1p
Localization
Cell Percentages cytoplasm (28%), vacuole (2%), mixed (41%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ape3

Ape3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ape3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available