Standard name | |
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Human Ortholog | |
Description | Mitochondrial inner membrane citrate transporter; member of the mitochondrial carrier family |
ensLOC | DeepLoc | |||||||||||||||||||||||
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Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 0 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8 | 3 | 5 | 11 | 10 | 6 | 0 | 1 | 6 | 4 | 6 | 5 |
Bud | 3 | 1 | 6 | 1 | 4 | 14 | 12 | 24 | 9 | 10 | 9 | 9 | 2 | 1 | 0 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 2 | 1 |
Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 1 | 6 | 6 | 13 | 4 | 7 | 6 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 1 | 4 | 6 | 0 | 1 | 1 | 3 | 4 | 4 | 3 | 2 | 4 | 2 | 2 | 2 | 5 | 8 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoplasm | 1 | 0 | 3 | 5 | 6 | 12 | 8 | 3 | 7 | 12 | 2 | 7 | 3 | 3 | 6 | 7 | 7 | 9 | 1 | 0 | 0 | 0 | 0 | 1 |
Endoplasmic Reticulum | 0 | 1 | 2 | 0 | 0 | 2 | 4 | 0 | 1 | 2 | 1 | 3 | 3 | 4 | 4 | 2 | 1 | 3 | 0 | 0 | 1 | 0 | 0 | 1 |
Endosome | 1 | 1 | 2 | 0 | 7 | 3 | 1 | 5 | 0 | 6 | 0 | 0 | 2 | 1 | 2 | 4 | 4 | 4 | 3 | 5 | 9 | 4 | 4 | 4 |
Golgi | 1 | 15 | 13 | 12 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 48 | 55 | 97 | 12 | 15 | 8 | 8 | 15 | 15 | 17 | 20 | 28 |
Mitochondria | 85 | 118 | 341 | 129 | 256 | 295 | 484 | 502 | 403 | 470 | 399 | 441 | 119 | 105 | 127 | 5 | 13 | 9 | 77 | 116 | 300 | 82 | 91 | 125 |
Nucleus | 2 | 0 | 0 | 0 | 1 | 12 | 6 | 21 | 2 | 13 | 7 | 2 | 2 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Nuclear Periphery | 2 | 3 | 13 | 0 | 18 | 22 | 38 | 15 | 27 | 21 | 18 | 26 | 3 | 3 | 7 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 2 |
Nucleolus | 9 | 8 | 13 | 6 | 22 | 18 | 49 | 55 | 29 | 27 | 19 | 19 | 7 | 5 | 1 | 0 | 2 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Peroxisomes | 0 | 2 | 2 | 0 | 8 | 1 | 2 | 8 | 2 | 7 | 0 | 1 | 2 | 5 | 2 | 0 | 0 | 1 | 1 | 1 | 9 | 4 | 8 | 5 |
SpindlePole | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 21 | 3 | 16 | 3 | 5 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Vac/Vac Membrane | 5 | 28 | 20 | 3 | 33 | 21 | 21 | 29 | 21 | 36 | 24 | 26 | 24 | 31 | 27 | 15 | 20 | 9 | 2 | 13 | 2 | 8 | 15 | 19 |
Unique Cell Count | 92 | 142 | 352 | 137 | 297 | 326 | 510 | 552 | 417 | 505 | 412 | 449 | 162 | 159 | 188 | 51 | 74 | 42 | 102 | 159 | 351 | 130 | 154 | 199 |
Labelled Cell Count | 110 | 183 | 421 | 157 | 360 | 410 | 639 | 700 | 512 | 630 | 490 | 547 | 225 | 218 | 281 | 63 | 89 | 57 | 102 | 159 | 351 | 130 | 154 | 199 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 9.0 | 14.2 | 9.8 | 10.8 | 8.3 | 6.1 | 5.0 | 4.8 | 5.0 | 4.6 | 4.6 | 4.5 | 18.3 | 16.0 | 14.2 | 7.8 | 8.1 | 8.6 | 15.7 | 15.1 | 17.4 |
Std Deviation (1e-4) | 2.4 | 3.8 | 2.2 | 2.7 | 2.3 | 1.6 | 1.2 | 1.2 | 1.1 | 1.2 | 1.0 | 1.1 | 5.2 | 3.8 | 3.6 | 1.4 | 1.8 | 2.0 | 4.8 | 5.3 | 4.4 |
Intensity Change (Log2) | – | – | – | 0.14 | -0.25 | -0.69 | -0.97 | -1.04 | -0.98 | -1.1 | -1.1 | -1.14 | 0.9 | 0.7 | 0.53 | -0.33 | -0.28 | -0.19 | 0.67 | 0.62 | 0.82 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud | 0 | 0 | 2.0 | 0.7 | 0 | 0.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoplasm | 0 | 0 | 2.5 | 0 | 0 | 0 | 1.7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoplasmic Reticulum | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Golgi | 2.3 | -2.2 | -3.5 | -4.4 | 0 | -4.0 | 0 | 0 | 0 | 8.4 | 9.5 | 13.2 | 0 | 0 | 0 |
Mitochondria | -1.4 | -5.0 | -3.4 | -1.4 | 0 | -0.2 | 0 | 0 | 0 | -8.0 | -9.7 | -9.5 | -16.7 | -16.5 | -14.7 |
Nucleus | 0 | 0 | 3.6 | 0 | 3.7 | 0 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0 | 1.4 | 1.8 | 2.3 | 0 | 1.7 | 0 | 0 | 0 | -1.1 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 0.4 | 2.1 | 1.1 | 3.3 | 0 | 2.0 | 0 | 0 | 0 | 0.3 | -0.3 | 0 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vacuole | -1.6 | 2.5 | 0.4 | -1.1 | -0.3 | -0.4 | 0.8 | 0.1 | 0.1 | 3.4 | 4.8 | 3.4 | 0 | 5.7 | 0 |
R1 | R2 | R3 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Concentration | 12.1454 | 11.5766 | 12.0193 | 10.1128 | 10.4635 | 11.6794 | 15.8886 | 13.8192 | 15.4723 | 14.6431 | 13.6093 | 15.0171 | 13.3165 | 10.0436 | 12.5494 | 10.7836 | 12.1149 | 11.943 |
Actin | 0.006 | 0.0143 | 0.0044 | 0.0123 | 0.0155 | 0.0055 | 0.0079 | 0.0095 | 0.0044 | 0.0045 | 0.022 | 0.0033 | 0.0039 | 0.002 | 0.0028 | 0.0007 | 0.0005 | 0.0005 |
Bud | 0.0007 | 0.0045 | 0.0013 | 0.0009 | 0.0016 | 0.0009 | 0.0003 | 0.0007 | 0.0005 | 0.0002 | 0.0006 | 0.0001 | 0.0004 | 0.0026 | 0.0003 | 0.0002 | 0 | 0.0001 |
Bud Neck | 0.0019 | 0.0009 | 0.0003 | 0.0002 | 0.0004 | 0.0009 | 0.0001 | 0.0001 | 0.0001 | 0.0003 | 0.0003 | 0.0002 | 0.0002 | 0.0002 | 0.0001 | 0.0001 | 0 | 0.0001 |
Bud Periphery | 0.0011 | 0.0061 | 0.0016 | 0.001 | 0.002 | 0.0017 | 0.0007 | 0.001 | 0.0013 | 0.0006 | 0.0018 | 0.0001 | 0.0007 | 0.0059 | 0.0008 | 0.0005 | 0 | 0.0002 |
Bud Site | 0.0031 | 0.0102 | 0.0018 | 0.0014 | 0.0102 | 0.0005 | 0.0005 | 0.0034 | 0.0008 | 0.0003 | 0.0005 | 0.0002 | 0.001 | 0.0028 | 0.0005 | 0.0002 | 0 | 0.0001 |
Cell Periphery | 0.0013 | 0.0019 | 0.0008 | 0.0002 | 0.0004 | 0.0004 | 0.0002 | 0.0003 | 0.0004 | 0.001 | 0.0004 | 0.0001 | 0.0003 | 0.0003 | 0.0015 | 0.0006 | 0.0001 | 0.0002 |
Cytoplasm | 0.0013 | 0.0006 | 0.0017 | 0.0005 | 0.0017 | 0.001 | 0.0008 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0 | 0 | 0 |
Cytoplasmic Foci | 0.0186 | 0.0122 | 0.0076 | 0.0075 | 0.0197 | 0.0079 | 0.0063 | 0.0064 | 0.003 | 0.0036 | 0.0027 | 0.0047 | 0.0054 | 0.0105 | 0.0052 | 0.0008 | 0.0013 | 0.0009 |
Eisosomes | 0.0003 | 0.0004 | 0.0003 | 0.0002 | 0.0003 | 0.0002 | 0.0003 | 0.0002 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0.0001 | 0.0001 |
Endoplasmic Reticulum | 0.0008 | 0.0003 | 0.0023 | 0.0002 | 0.0025 | 0.001 | 0.0005 | 0.0001 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0002 | 0.0001 | 0.0002 | 0 | 0 | 0.0001 |
Endosome | 0.0333 | 0.0368 | 0.0166 | 0.0245 | 0.0475 | 0.0155 | 0.013 | 0.0076 | 0.0066 | 0.0156 | 0.0044 | 0.0046 | 0.0112 | 0.0198 | 0.0098 | 0.0059 | 0.0037 | 0.0071 |
Golgi | 0.0339 | 0.0593 | 0.0259 | 0.0313 | 0.0792 | 0.0252 | 0.0234 | 0.0262 | 0.0191 | 0.0216 | 0.0058 | 0.0146 | 0.0181 | 0.0296 | 0.0151 | 0.0111 | 0.0085 | 0.0194 |
Lipid Particles | 0.0316 | 0.0292 | 0.0181 | 0.0309 | 0.0524 | 0.0116 | 0.0197 | 0.0234 | 0.0067 | 0.0061 | 0.0089 | 0.0141 | 0.0372 | 0.0207 | 0.0124 | 0.0061 | 0.0192 | 0.0172 |
Mitochondria | 0.7742 | 0.7466 | 0.8734 | 0.8559 | 0.7046 | 0.8831 | 0.891 | 0.8658 | 0.9294 | 0.8995 | 0.9015 | 0.9352 | 0.8749 | 0.8543 | 0.9115 | 0.9432 | 0.9546 | 0.9273 |
None | 0.0026 | 0.0001 | 0.0045 | 0.0001 | 0.0041 | 0.0004 | 0.0007 | 0 | 0.0001 | 0.0001 | 0.0002 | 0.0003 | 0.0002 | 0.0001 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0.0064 | 0.0003 | 0.0013 | 0.0001 | 0.0215 | 0.0008 | 0.0018 | 0.0001 | 0.0001 | 0.0001 | 0.0005 | 0.0007 | 0.0028 | 0.0003 | 0.0001 | 0 | 0 | 0.0001 |
Nucleolus | 0.0074 | 0.0046 | 0.0009 | 0.0003 | 0.0016 | 0.002 | 0.0027 | 0.0015 | 0.0033 | 0.0005 | 0.0052 | 0.0004 | 0.0076 | 0.0007 | 0.0016 | 0.0003 | 0.0001 | 0.0055 |
Nucleus | 0.0036 | 0.0011 | 0.0007 | 0.0002 | 0.005 | 0.0008 | 0.0014 | 0.0002 | 0.0002 | 0.0002 | 0.0025 | 0.0005 | 0.0006 | 0.0003 | 0.0003 | 0.0001 | 0 | 0.0004 |
Peroxisomes | 0.0125 | 0.0182 | 0.0103 | 0.0236 | 0.0069 | 0.0066 | 0.0125 | 0.0253 | 0.0112 | 0.0124 | 0.0198 | 0.0114 | 0.0137 | 0.0224 | 0.0082 | 0.0027 | 0.0067 | 0.0076 |
Punctate Nuclear | 0.008 | 0.0001 | 0.0003 | 0.0004 | 0.0048 | 0.0003 | 0.0026 | 0 | 0 | 0 | 0.0008 | 0.0014 | 0.0001 | 0 | 0 | 0 | 0 | 0 |
Vacuole | 0.0182 | 0.0291 | 0.01 | 0.0049 | 0.008 | 0.0122 | 0.0037 | 0.0066 | 0.0048 | 0.023 | 0.0052 | 0.0012 | 0.0054 | 0.0093 | 0.0131 | 0.0092 | 0.0006 | 0.0039 |
Vacuole Periphery | 0.0335 | 0.0233 | 0.0159 | 0.0036 | 0.0102 | 0.0214 | 0.01 | 0.0214 | 0.0074 | 0.0103 | 0.0162 | 0.0065 | 0.0158 | 0.0176 | 0.0161 | 0.0178 | 0.0043 | 0.0092 |
R1 | R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Gene Expression | 87.6594 | 81.102 | 69.1271 | 68.1251 | 61.9932 | 74.7449 | 92.5295 | 93.1158 | 78.6671 | 73.1326 |
Translational Efficiency | 1.2683 | 1.5699 | 1.4809 | 1.3731 | 1.2409 | 1.8745 | 1.5364 | 1.1288 | 1.3557 | 1.2875 |
Dataset | Hit |
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Protein Concentration | ✘ |
Protein Localization | ✘ |
Gene Expression | ✔ |
Translational Efficiency | ✘ |
Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
---|---|---|---|---|
37℃ | ||||
RT |
Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
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Gene | Images |
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Gene | Images |
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