Standard name
Human Ortholog
Description Mitochondrial inner membrane citrate transporter; member of the mitochondrial carrier family

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.22 0.14 0.14 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.11 0.07 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.14 0.09 0.21 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.1 0 0 0 0 0 0
Golgi 0 0.11 0 0.09 0 0 0 0 0 0 0 0 0.3 0.35 0.52 0.24 0.2 0.19 0.09 0.1 0 0.13 0.13 0.14
Mitochondria 0.92 0.83 0.97 0.94 0.86 0.9 0.95 0.91 0.97 0.93 0.97 0.98 0.73 0.66 0.68 0.1 0.18 0.21 0.76 0.73 0.86 0.63 0.59 0.63
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0.06 0.07 0.07 0 0.06 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.1 0.06 0 0 0.07 0.06 0.1 0.1 0.07 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0.2 0.06 0 0.11 0.06 0 0.05 0.05 0.07 0.06 0.06 0.15 0.19 0.14 0.29 0.27 0.21 0 0.08 0 0.07 0.1 0.1
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 0 1 0 1 0 0 0 0 0 1 8 3 5 11 10 6 0 1 6 4 6 5
Bud 3 1 6 1 4 14 12 24 9 10 9 9 2 1 0 1 3 2 0 0 0 0 2 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0
Bud Site 0 0 0 0 1 6 6 13 4 7 6 3 0 0 0 0 0 0
Cell Periphery 1 4 6 0 1 1 3 4 4 3 2 4 2 2 2 5 8 3 0 0 0 0 0 0
Cytoplasm 1 0 3 5 6 12 8 3 7 12 2 7 3 3 6 7 7 9 1 0 0 0 0 1
Endoplasmic Reticulum 0 1 2 0 0 2 4 0 1 2 1 3 3 4 4 2 1 3 0 0 1 0 0 1
Endosome 1 1 2 0 7 3 1 5 0 6 0 0 2 1 2 4 4 4 3 5 9 4 4 4
Golgi 1 15 13 12 3 0 0 0 0 0 0 0 48 55 97 12 15 8 8 15 15 17 20 28
Mitochondria 85 118 341 129 256 295 484 502 403 470 399 441 119 105 127 5 13 9 77 116 300 82 91 125
Nucleus 2 0 0 0 1 12 6 21 2 13 7 2 2 0 0 0 4 1 0 0 0 0 0 1
Nuclear Periphery 2 3 13 0 18 22 38 15 27 21 18 26 3 3 7 0 1 1 1 1 1 2 0 2
Nucleolus 9 8 13 6 22 18 49 55 29 27 19 19 7 5 1 0 2 1 1 0 0 0 1 1
Peroxisomes 0 2 2 0 8 1 2 8 2 7 0 1 2 5 2 0 0 1 1 1 9 4 8 5
SpindlePole 0 0 0 0 0 2 5 21 3 16 3 5 0 0 1 1 1 0 0 1 0 0 0 0
Vac/Vac Membrane 5 28 20 3 33 21 21 29 21 36 24 26 24 31 27 15 20 9 2 13 2 8 15 19
Unique Cell Count 92 142 352 137 297 326 510 552 417 505 412 449 162 159 188 51 74 42 102 159 351 130 154 199
Labelled Cell Count 110 183 421 157 360 410 639 700 512 630 490 547 225 218 281 63 89 57 102 159 351 130 154 199


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.0 14.2 9.8 10.8 8.3 6.1 5.0 4.8 5.0 4.6 4.6 4.5 18.3 16.0 14.2 7.8 8.1 8.6 15.7 15.1 17.4
Std Deviation (1e-4) 2.4 3.8 2.2 2.7 2.3 1.6 1.2 1.2 1.1 1.2 1.0 1.1 5.2 3.8 3.6 1.4 1.8 2.0 4.8 5.3 4.4
Intensity Change (Log2) 0.14 -0.25 -0.69 -0.97 -1.04 -0.98 -1.1 -1.1 -1.14 0.9 0.7 0.53 -0.33 -0.28 -0.19 0.67 0.62 0.82


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 2.0 0.7 0 0.5 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 2.5 0 0 0 1.7 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 2.3 -2.2 -3.5 -4.4 0 -4.0 0 0 0 8.4 9.5 13.2 0 0 0
Mitochondria -1.4 -5.0 -3.4 -1.4 0 -0.2 0 0 0 -8.0 -9.7 -9.5 -16.7 -16.5 -14.7
Nucleus 0 0 3.6 0 3.7 0 3.0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 1.4 1.8 2.3 0 1.7 0 0 0 -1.1 0 0 0 0 0
Nucleolus 0.4 2.1 1.1 3.3 0 2.0 0 0 0 0.3 -0.3 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.6 2.5 0.4 -1.1 -0.3 -0.4 0.8 0.1 0.1 3.4 4.8 3.4 0 5.7 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.1454 11.5766 12.0193 10.1128 10.4635 11.6794 15.8886 13.8192 15.4723 14.6431 13.6093 15.0171 13.3165 10.0436 12.5494 10.7836 12.1149 11.943
Actin 0.006 0.0143 0.0044 0.0123 0.0155 0.0055 0.0079 0.0095 0.0044 0.0045 0.022 0.0033 0.0039 0.002 0.0028 0.0007 0.0005 0.0005
Bud 0.0007 0.0045 0.0013 0.0009 0.0016 0.0009 0.0003 0.0007 0.0005 0.0002 0.0006 0.0001 0.0004 0.0026 0.0003 0.0002 0 0.0001
Bud Neck 0.0019 0.0009 0.0003 0.0002 0.0004 0.0009 0.0001 0.0001 0.0001 0.0003 0.0003 0.0002 0.0002 0.0002 0.0001 0.0001 0 0.0001
Bud Periphery 0.0011 0.0061 0.0016 0.001 0.002 0.0017 0.0007 0.001 0.0013 0.0006 0.0018 0.0001 0.0007 0.0059 0.0008 0.0005 0 0.0002
Bud Site 0.0031 0.0102 0.0018 0.0014 0.0102 0.0005 0.0005 0.0034 0.0008 0.0003 0.0005 0.0002 0.001 0.0028 0.0005 0.0002 0 0.0001
Cell Periphery 0.0013 0.0019 0.0008 0.0002 0.0004 0.0004 0.0002 0.0003 0.0004 0.001 0.0004 0.0001 0.0003 0.0003 0.0015 0.0006 0.0001 0.0002
Cytoplasm 0.0013 0.0006 0.0017 0.0005 0.0017 0.001 0.0008 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0002 0.0002 0 0 0
Cytoplasmic Foci 0.0186 0.0122 0.0076 0.0075 0.0197 0.0079 0.0063 0.0064 0.003 0.0036 0.0027 0.0047 0.0054 0.0105 0.0052 0.0008 0.0013 0.0009
Eisosomes 0.0003 0.0004 0.0003 0.0002 0.0003 0.0002 0.0003 0.0002 0.0002 0.0001 0.0002 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0008 0.0003 0.0023 0.0002 0.0025 0.001 0.0005 0.0001 0.0001 0.0001 0.0003 0.0001 0.0002 0.0001 0.0002 0 0 0.0001
Endosome 0.0333 0.0368 0.0166 0.0245 0.0475 0.0155 0.013 0.0076 0.0066 0.0156 0.0044 0.0046 0.0112 0.0198 0.0098 0.0059 0.0037 0.0071
Golgi 0.0339 0.0593 0.0259 0.0313 0.0792 0.0252 0.0234 0.0262 0.0191 0.0216 0.0058 0.0146 0.0181 0.0296 0.0151 0.0111 0.0085 0.0194
Lipid Particles 0.0316 0.0292 0.0181 0.0309 0.0524 0.0116 0.0197 0.0234 0.0067 0.0061 0.0089 0.0141 0.0372 0.0207 0.0124 0.0061 0.0192 0.0172
Mitochondria 0.7742 0.7466 0.8734 0.8559 0.7046 0.8831 0.891 0.8658 0.9294 0.8995 0.9015 0.9352 0.8749 0.8543 0.9115 0.9432 0.9546 0.9273
None 0.0026 0.0001 0.0045 0.0001 0.0041 0.0004 0.0007 0 0.0001 0.0001 0.0002 0.0003 0.0002 0.0001 0 0 0 0
Nuclear Periphery 0.0064 0.0003 0.0013 0.0001 0.0215 0.0008 0.0018 0.0001 0.0001 0.0001 0.0005 0.0007 0.0028 0.0003 0.0001 0 0 0.0001
Nucleolus 0.0074 0.0046 0.0009 0.0003 0.0016 0.002 0.0027 0.0015 0.0033 0.0005 0.0052 0.0004 0.0076 0.0007 0.0016 0.0003 0.0001 0.0055
Nucleus 0.0036 0.0011 0.0007 0.0002 0.005 0.0008 0.0014 0.0002 0.0002 0.0002 0.0025 0.0005 0.0006 0.0003 0.0003 0.0001 0 0.0004
Peroxisomes 0.0125 0.0182 0.0103 0.0236 0.0069 0.0066 0.0125 0.0253 0.0112 0.0124 0.0198 0.0114 0.0137 0.0224 0.0082 0.0027 0.0067 0.0076
Punctate Nuclear 0.008 0.0001 0.0003 0.0004 0.0048 0.0003 0.0026 0 0 0 0.0008 0.0014 0.0001 0 0 0 0 0
Vacuole 0.0182 0.0291 0.01 0.0049 0.008 0.0122 0.0037 0.0066 0.0048 0.023 0.0052 0.0012 0.0054 0.0093 0.0131 0.0092 0.0006 0.0039
Vacuole Periphery 0.0335 0.0233 0.0159 0.0036 0.0102 0.0214 0.01 0.0214 0.0074 0.0103 0.0162 0.0065 0.0158 0.0176 0.0161 0.0178 0.0043 0.0092

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 87.6594 81.102 69.1271 68.1251 61.9932 74.7449 92.5295 93.1158 78.6671 73.1326
Translational Efficiency 1.2683 1.5699 1.4809 1.3731 1.2409 1.8745 1.5364 1.1288 1.3557 1.2875

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency
Standard name
Human Ortholog
Description Mitochondrial inner membrane citrate transporter; member of the mitochondrial carrier family
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Ctp1

Ctp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ctp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available