Standard name
Human Ortholog
Description Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0.07 0.05 0.07 0.07 0 0.06 0.05 0 0.11 0.12 0.05 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.11 0 0 0 0 0 0 0.1 0.09 0.12 0.14 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.96 0.86 0.93 0.9 0.91 0.86 0.84 0.81 0.73 0.79 0.69 0.67 0.78 0.86 0.81 0.91 0.89 0.87 0.83 0.8 0.84 0.79 0.76 0.67
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.25 0.21 0.09 0.11 0.05 0.1 0.14 0.15 0.4 0.31 0.52 0.41 0.17 0 0.08 0.1 0.14 0.18 0.09 0.06 0.09 0.11 0.11 0.17
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0.06 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 1 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 1
Bud Neck 0 0 0 1 0 0 1 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 6 4 6 3 2 2 0 1 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 3 6 17 16 15 15 19 14 9 5 6 2 20 21 7 5 3 0 2 0 0 1 0
Endoplasmic Reticulum 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 4 1 3 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 2 1 1 1 2 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1
Mitochondria 0 8 1 4 1 5 4 2 19 25 10 18 0 1 0 8 3 1 0 2 1 0 0 1
Nucleus 85 60 227 487 259 175 234 209 141 221 59 85 36 160 145 135 134 141 91 72 215 60 121 93
Nuclear Periphery 0 0 1 0 0 1 3 1 1 1 0 1 1 0 4 2 1 4 0 0 0 0 0 0
Nucleolus 22 15 22 59 15 20 38 38 78 88 45 52 8 7 14 15 21 29 10 5 24 8 18 24
Peroxisomes 2 0 0 1 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 2 0 2 0 0 0 1 3 0 0 0 1 2 3 5 1 1 2 1 0 1 0 0 3
Vac/Vac Membrane 0 1 2 2 2 4 2 5 1 1 0 0 3 2 4 3 3 0 1 3 6 2 10 10
Unique Cell Count 89 70 245 539 286 203 280 257 193 281 86 126 46 186 178 149 150 162 110 91 257 77 161 140
Labelled Cell Count 111 90 261 572 293 220 305 283 262 352 121 165 53 195 195 176 171 184 110 91 257 77 161 140


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.5 6.2 8.9 8.4 9.5 7.5 7.1 7.2 6.3 6.5 5.9 5.8 7.6 8.1 7.8 6.6 8.5 8.4 9.4 9.6 8.8
Std Deviation (1e-4) 1.7 1.2 1.6 1.8 3.2 1.6 1.7 1.8 1.9 1.6 1.6 1.2 1.9 2.3 2.3 1.4 2.2 2.1 2.0 2.0 1.9
Intensity Change (Log2) – – – -0.09 0.09 -0.26 -0.33 -0.31 -0.51 -0.47 -0.59 -0.63 -0.23 -0.13 -0.19 -0.44 -0.07 -0.1 0.08 0.1 -0.03

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.5 1.8 2.5 1.7 2.5 2.4 0.5 0 0 0 3.6 3.9 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 4.7 4.5 0 5.7 0 0 0 0 0 0
Nucleus -1.0 -0.9 -2.2 -3.2 -3.8 -5.6 -4.5 -5.6 -6.3 -3.0 -2.3 -3.5 -0.7 -1.1 -1.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.8 -1.7 0.3 1.6 2.0 7.8 6.3 8.6 7.4 0 -2.1 -0.4 0.4 1.6 2.7
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.2278 2.9085 2.9698 2.1086 2.4898 2.773 6.0845 6.0837 6.1375 6.0522 5.6588 5.8158 3.2857 3.5777 3.2223 2.9003 2.6304 3.0867
Actin 0.036 0.0003 0.007 0 0.0016 0.0004 0.0089 0 0.0009 0 0.0241 0.0003 0.0013 0 0.0043 0.0035 0.035 0.0028
Bud 0.0005 0.0001 0.0005 0 0.0001 0.0001 0.0004 0 0.0002 0 0.0006 0.0004 0.0006 0 0.0002 0.0002 0.0007 0.0001
Bud Neck 0.0012 0.0002 0.0015 0.0001 0.0007 0.0005 0.0045 0.0002 0.001 0.0001 0.0004 0.0008 0.0017 0.0001 0.0004 0.0003 0.0027 0.0025
Bud Periphery 0.0012 0.0006 0.0009 0 0.0003 0.0005 0.0008 0 0.0004 0 0.0012 0.001 0.0016 0 0.0004 0.0003 0.0006 0.0002
Bud Site 0.0024 0.0003 0.0027 0 0.0003 0.0002 0.0056 0.0001 0.0016 0 0.0012 0.0008 0.0014 0.0001 0.0014 0.0007 0.0077 0.0002
Cell Periphery 0.0006 0.0002 0.0002 0 0.0001 0.0002 0.0003 0 0.0002 0 0.0001 0.0003 0.0004 0 0.0001 0.0001 0.0002 0.0001
Cytoplasm 0.0013 0 0.0013 0 0.0001 0.0003 0.0027 0 0.0002 0 0.0004 0.0007 0.0023 0 0.008 0.0002 0.0095 0.0004
Cytoplasmic Foci 0.0074 0.0003 0.0054 0 0.0192 0.0002 0.0104 0 0.0001 0 0.0021 0.0023 0.0051 0 0.0031 0.0083 0.0313 0.0004
Eisosomes 0.0002 0.0001 0.0001 0 0 0 0.0001 0 0.0001 0 0.0001 0 0 0 0 0.0001 0.0001 0
Endoplasmic Reticulum 0.0037 0.0001 0.0015 0 0 0.0007 0.0015 0 0.0002 0 0.0041 0.0004 0.0005 0 0.0004 0.0006 0.0014 0.0007
Endosome 0.0107 0.0002 0.0127 0 0.0007 0.0007 0.0082 0 0.0002 0 0.0091 0.0011 0.0023 0 0.007 0.0175 0.0385 0.0041
Golgi 0.0046 0.0002 0.0049 0 0.0009 0.0001 0.0035 0 0.0001 0 0.0063 0.0011 0.0017 0 0.0047 0.0121 0.0083 0.0086
Lipid Particles 0.0067 0.0043 0.0123 0 0.0053 0.0009 0.0084 0 0.0002 0 0.0015 0.0018 0.006 0 0.0056 0.0357 0.0099 0.0006
Mitochondria 0.0052 0.0058 0.008 0.0001 0.0011 0.0041 0.0036 0.0001 0.0014 0 0.0156 0.0007 0.0057 0.0003 0.0036 0.0394 0.0024 0.0028
None 0.0011 0.0002 0.001 0 0.0002 0.0002 0.006 0 0.0003 0 0.0006 0.0001 0.0008 0 0.0002 0.0002 0.0031 0.0001
Nuclear Periphery 0.0089 0.0072 0.0064 0.0002 0.0012 0.0102 0.0117 0.0003 0.0007 0.0001 0.0244 0.0002 0.0046 0.0001 0.0011 0.0023 0.0026 0.0023
Nucleolus 0.0406 0.0363 0.028 0.0102 0.1817 0.0802 0.0447 0.0252 0.0184 0.0165 0.0852 0.0773 0.0449 0.0251 0.0162 0.0197 0.0886 0.0738
Nucleus 0.846 0.9398 0.892 0.9893 0.7717 0.8972 0.8496 0.9729 0.9726 0.9831 0.8141 0.9058 0.8925 0.974 0.939 0.8478 0.7386 0.899
Peroxisomes 0.0015 0.0006 0.0037 0 0.011 0.0001 0.0041 0 0.0001 0 0.0022 0.0028 0.0086 0 0.0024 0.0045 0.0043 0.0001
Punctate Nuclear 0.0173 0.0018 0.0061 0.0001 0.0031 0.001 0.0223 0.001 0.0008 0.0001 0.0041 0.0005 0.0144 0.0001 0.0004 0.0011 0.0121 0.0003
Vacuole 0.002 0.0005 0.0023 0 0.0004 0.001 0.0018 0 0.0003 0 0.0008 0.0013 0.0026 0 0.0011 0.0029 0.002 0.0007
Vacuole Periphery 0.0011 0.001 0.0014 0 0.0002 0.0011 0.001 0 0.0001 0 0.0016 0.0001 0.001 0 0.0004 0.0025 0.0005 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 29.707 26.5563 23.4594 28.532 28.4288 46.6567 31.3262 33.2248 44.3713 32.6404
Translational Efficiency 1.0841 0.9471 1.051 1.1002 1.0051 0.6182 0.7548 0.8854 0.6382 0.7614

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
37 596 216 1793 1656 1802 460 887 1693 2398 676 2680

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 887.60 1047.31 1230.64 1074.55 777.91 1040.84 1121.35 1048.51 780.31 1042.45 1156.27 1065.93
Standard Deviation 231.94 150.30 163.98 157.75 138.40 137.88 192.54 180.33 142.02 141.10 190.83 166.02
Intensity Change Log 2 — 0.238707 0.471427 0.275751 — 0.420073 0.527561 0.430665 — 0.326261 0.497918 0.350181

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001748 0.000591 0.001440 0.001228 0.000500 0.000387 0.001031 0.001137 0.000527 0.000438 0.001162 0.001198
Bud Neck 0.036900 0.010459 0.014057 0.046439 0.005734 0.011858 0.012424 0.022397 0.006415 0.011510 0.012946 0.038482
Bud Site 0.028866 0.000894 0.001664 0.008570 0.001162 0.001670 0.001163 0.002090 0.001767 0.001477 0.001323 0.006425
Cell Periphery 0.000370 0.000043 0.000047 0.000183 0.000293 0.000118 0.000114 0.000147 0.000295 0.000099 0.000092 0.000171
Cytoplasm 0.029162 0.000420 0.000214 0.005878 0.003332 0.000536 0.003581 0.004833 0.003896 0.000507 0.002505 0.005532
Cytoplasmic Foci 0.037896 0.000150 0.000065 0.003640 0.000322 0.000248 0.001156 0.003048 0.001144 0.000224 0.000807 0.003444
Eisosomes 0.000151 0.000056 0.000086 0.000038 0.000042 0.000065 0.000069 0.000043 0.000044 0.000063 0.000074 0.000040
Endoplasmic Reticulum 0.009630 0.002134 0.002704 0.003725 0.002991 0.003064 0.002431 0.003046 0.003136 0.002833 0.002518 0.003500
Endosome 0.040365 0.000070 0.000101 0.005253 0.000405 0.000942 0.000483 0.001092 0.001278 0.000725 0.000361 0.003876
Golgi 0.008885 0.000071 0.000151 0.004466 0.000480 0.000134 0.000135 0.001207 0.000664 0.000118 0.000140 0.003388
Lipid Particles 0.005926 0.000029 0.000085 0.000390 0.000052 0.000121 0.000495 0.000097 0.000180 0.000098 0.000364 0.000293
Mitochondria 0.012598 0.000763 0.001786 0.008092 0.000585 0.001936 0.001293 0.002219 0.000847 0.001644 0.001450 0.006148
Mitotic Spindle 0.007530 0.001949 0.001126 0.053340 0.000032 0.001700 0.000551 0.010313 0.000196 0.001762 0.000734 0.039099
None 0.005980 0.001122 0.001036 0.004958 0.011225 0.000788 0.013765 0.007033 0.011111 0.000871 0.009698 0.005645
Nuclear Periphery 0.000616 0.000063 0.000138 0.004019 0.000055 0.000246 0.000150 0.001170 0.000068 0.000201 0.000146 0.003076
Nuclear Periphery Foci 0.017675 0.000072 0.000088 0.001104 0.000231 0.000198 0.000132 0.000427 0.000612 0.000167 0.000118 0.000880
Nucleolus 0.054634 0.084488 0.055396 0.015333 0.056634 0.066612 0.046534 0.026463 0.056591 0.071055 0.049366 0.019017
Nucleus 0.622728 0.894832 0.915970 0.817833 0.914344 0.906260 0.911947 0.911097 0.907971 0.903420 0.913232 0.848700
Peroxisomes 0.015148 0.001023 0.002391 0.001487 0.000478 0.000461 0.001751 0.000551 0.000799 0.000601 0.001955 0.001177
Vacuole 0.054284 0.000220 0.001261 0.008809 0.000797 0.001613 0.000647 0.001237 0.001966 0.001267 0.000843 0.006303
Vacuole Periphery 0.008908 0.000552 0.000196 0.005218 0.000306 0.001043 0.000149 0.000353 0.000494 0.000921 0.000164 0.003607

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.40 -0.17 0.68 -12.74 2.06 2.74 -10.55 -15.06 -16.12 -1.80 2.34 -13.46 -18.35 -20.08 -0.68
Bud Neck 1.77 1.43 -0.72 -17.69 -14.98 -7.46 -8.34 -12.42 -8.48 -6.35 -6.72 -9.53 -23.72 -19.48 -16.11
Bud Site 2.20 2.10 1.74 -7.26 -5.60 -1.14 -0.91 -4.80 -2.58 -6.23 0.56 0.20 -5.51 -6.54 -6.92
Cell Periphery 2.76 2.63 1.91 -4.40 -3.94 1.35 1.50 1.23 -0.61 -1.32 1.55 1.67 1.27 -1.53 -2.34
Cytoplasm 2.05 2.05 1.75 -6.76 -7.05 3.31 0.45 -1.14 -3.50 -1.41 3.93 1.82 -1.05 -7.10 -3.37
Cytoplasmic Foci 2.88 2.88 2.78 -3.35 -3.72 0.36 -1.09 -1.49 -1.57 -0.81 2.51 0.96 -0.69 -3.04 -1.56
Eisosomes 4.05 2.33 4.72 3.01 10.21 -5.49 -6.92 -1.45 5.37 7.02 -4.84 -8.85 0.26 6.91 12.02
Endoplasmic Reticulum 3.24 2.60 2.22 -11.08 -2.03 -0.29 1.83 -1.83 -1.24 -3.95 1.11 1.11 -4.34 -5.69 -5.81
Endosome 2.70 2.70 2.58 -4.86 -4.62 -1.75 -0.05 -1.14 0.29 -0.94 1.45 2.20 -0.54 -2.83 -3.80
Golgi 2.71 2.67 2.16 -4.04 -3.74 0.92 0.90 -0.68 -1.64 -1.63 1.50 1.39 -1.79 -4.24 -4.13
Lipid Particles 2.10 2.06 2.01 -5.06 -2.34 -1.76 -1.42 -2.80 0.00 1.12 1.03 -0.82 -0.68 -2.67 0.59
Mitochondria 2.41 2.16 1.20 -8.18 -6.39 -3.28 -9.47 -8.88 -1.46 -4.57 -2.51 -6.18 -9.09 -6.14 -7.44
Mitotic Spindle 1.90 1.86 -4.48 -9.55 -9.63 -2.69 -1.77 -4.90 -4.29 -2.25 -2.39 -1.93 -11.91 -11.05 -7.93
None 2.27 2.27 0.47 -6.62 -7.62 7.29 0.01 2.86 -5.92 1.40 7.30 1.17 4.01 -9.88 1.18
Nuclear Periphery 2.75 2.04 -4.30 -5.63 -5.36 -4.32 -7.62 -3.28 -2.71 -2.96 -3.96 -7.41 -6.34 -5.96 -6.04
Nuclear Periphery Foci 2.64 2.63 2.55 -4.35 -3.71 -0.13 1.80 -1.90 -1.76 -2.24 2.29 2.82 -0.54 -3.52 -4.37
Nucleolus -2.40 -0.44 3.36 14.77 6.51 -3.42 1.43 9.72 12.51 4.91 -5.29 0.65 15.81 21.97 9.19
Nucleus -4.95 -5.07 -4.14 6.69 6.38 1.92 1.65 3.12 1.74 0.89 0.93 0.72 8.47 8.32 6.34
Peroxisomes 2.42 2.15 2.46 0.83 4.67 0.09 -6.33 -2.19 -1.67 5.83 1.31 -5.94 0.39 -0.48 5.39
Vacuole 4.06 3.91 3.54 -7.23 -4.27 -1.90 -0.05 -2.46 -0.99 -2.59 1.47 1.61 -4.60 -5.95 -6.14
Vacuole Periphery 2.01 2.10 1.60 -2.25 -3.22 -3.36 1.74 -0.12 3.34 -2.09 -1.98 2.52 -2.53 -1.43 -3.39
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Sgf29

Sgf29


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sgf29-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available