Standard name
Human Ortholog
Description Subunit of a complex with Ctf8p and Ctf18p; shares some components with Replication Factor C; required for sister chromatid cohesion and telomere length maintenance
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0.09 0.06 0.08 0.07 0.06 0.09 0.12 0.13 0.07 0.06 0.13 0.17 0.37 0.06 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.26 0.1 0 0.08 0.08 0.21 0.27 0.26 0.43 0.35 0.43 0.51 0 0 0 0.11 0.09 0.15 0 0 0 0 0 0
Nucleus 0.93 0.98 0.9 0.87 0.87 0.79 0.76 0.76 0.74 0.65 0.63 0.73 0.93 0.86 0.82 0.68 0.83 0.9 0.92 0.9 0.79 0.85 0.84 0.82
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.06 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.07 0.08 0 0 0 0 0 0.08 0.08 0 0 0.07 0.07 0.08 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 1
Bud 1 0 0 0 0 5 9 5 2 2 3 7 0 0 1 0 0 0 3 0 0 2 3 5
Bud Neck 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1
Bud Site 0 0 1 1 6 7 13 12 4 4 2 14 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 1 1 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0
Cytoplasm 4 0 14 18 22 25 39 29 21 42 34 24 25 82 119 7 5 3 0 0 2 3 7 13
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 2 2 2 0 0 1 0 1 0
Endosome 0 0 1 1 3 2 2 7 1 5 3 2 1 2 3 0 1 0 1 1 1 1 2 5
Golgi 0 0 0 0 2 0 0 0 0 0 1 0 0 0 1 0 1 0 1 0 1 0 0 2
Mitochondria 83 9 8 17 29 66 142 122 102 119 110 184 3 2 1 2 7 7 0 0 6 1 8 7
Nucleus 296 86 238 183 321 253 395 351 175 220 162 265 379 551 579 13 65 43 284 86 221 141 403 439
Nuclear Periphery 0 0 4 8 0 9 11 8 3 3 5 16 2 12 2 0 1 1 0 0 1 0 1 0
Nucleolus 3 5 7 6 15 12 19 23 10 13 9 10 4 3 9 0 1 1 3 0 7 0 4 3
Peroxisomes 0 0 1 0 0 1 0 0 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0
SpindlePole 2 0 1 2 2 0 4 6 1 1 0 4 2 6 12 0 0 0 1 1 2 0 4 3
Vac/Vac Membrane 2 2 7 2 7 8 20 19 4 22 21 10 3 3 7 0 6 4 10 3 18 12 36 47
Unique Cell Count 319 88 265 211 369 319 523 462 238 336 257 364 407 643 710 19 78 48 310 96 280 167 483 538
Labelled Cell Count 391 102 282 238 407 388 657 583 323 433 350 536 419 662 740 24 89 61 310 96 280 167 483 538


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 5.1 6.0 6.0 5.7 5.1 5.0 4.7 4.5 5.0 4.5 4.1 6.8 6.5 6.4 7.8 7.0 6.8 5.9 6.3 6.9
Std Deviation (1e-4) 0.7 0.8 2.4 3.5 2.6 3.9 3.9 2.3 2.5 3.5 2.7 1.9 1.6 1.4 1.4 2.1 1.8 1.2 1.1 1.3 1.6
Intensity Change (Log2) – – – 0.01 -0.08 -0.22 -0.26 -0.35 -0.4 -0.26 -0.4 -0.55 0.18 0.13 0.09 0.39 0.23 0.19 -0.02 0.08 0.2

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 0.4 1.2 1.2 0.5 1.6 3.0 3.1 0.7 0.5 3.3 4.6 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.4 2.6 6.4 8.2 0 0 9.7 0 0 0 0 0 0 0 0
Nucleus -1.0 -1.1 -3.5 -4.8 -4.6 -4.8 -7.0 -7.2 -5.3 1.5 -1.7 -3.1 -2.8 -1.6 0
Nuclear Periphery 1.6 0 1.1 0.6 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.1 1.0 0.8 0.7 0 0 0.8 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 -0.6 -0.1 0.9 1.0 -0.7 2.2 2.8 0.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2183 0.9736 0.9023 0.9506 0.8375 0.93 0.7506 1.1998 0.9728 0.805 0.6447 0.8901 -0.2671 0.1874 -0.2052 0.4039 0.093 -0.3352
Actin 0.0309 0.0011 0.0045 0.0083 0.0165 0.0025 0.022 0.0016 0.0162 0.0037 0.0166 0.0034 0.0127 0.0001 0.0013 0.0628 0.0064 0.0003
Bud 0.0007 0.0001 0.0021 0.0003 0.0006 0.0046 0.0011 0.0001 0.0007 0.0004 0.0005 0.0006 0.0001 0 0 0.0001 0.0002 0.0001
Bud Neck 0.0035 0.0002 0.0004 0.0013 0.0021 0.0019 0.0141 0.0001 0.005 0.0005 0.0004 0.0006 0.0005 0.0001 0.0002 0.0002 0.0037 0.0023
Bud Periphery 0.0008 0.0001 0.0013 0.0008 0.0006 0.0013 0.002 0 0.0013 0.0006 0.001 0.0015 0.0002 0 0 0.0002 0.0002 0.0004
Bud Site 0.0015 0.0033 0.0026 0.0013 0.0014 0.0006 0.0069 0.0015 0.0048 0.0016 0.0007 0.0003 0.0003 0.0001 0.0001 0.0002 0.0005 0.0002
Cell Periphery 0.0003 0 0.0002 0.0002 0.0002 0.0001 0.0004 0 0.0003 0.0001 0.0001 0.0001 0 0 0 0 0.0001 0.0001
Cytoplasm 0.0135 0.0101 0.0096 0.0047 0.0044 0.0034 0.0084 0.0019 0.0037 0.0112 0.0005 0.0006 0.0043 0.0011 0.0005 0.0001 0.0026 0.0002
Cytoplasmic Foci 0.0178 0.003 0.0037 0.0053 0.0033 0.0012 0.0099 0.0021 0.012 0.0097 0.0051 0.0016 0.0028 0 0.0003 0.0004 0.0018 0.0001
Eisosomes 0.0003 0 0.0001 0 0.0004 0 0.0002 0 0.0001 0.0001 0.0001 0 0.0001 0 0 0.0002 0 0
Endoplasmic Reticulum 0.0042 0.0001 0.0011 0.0044 0.0045 0.0008 0.0031 0.0003 0.0007 0.0021 0.0009 0.0006 0.0022 0.0001 0.0004 0.0002 0.0016 0.0001
Endosome 0.0239 0.0007 0.0097 0.027 0.0266 0.0059 0.0315 0.0029 0.0109 0.0429 0.0228 0.0069 0.013 0.0001 0.0024 0.0013 0.0051 0.0008
Golgi 0.0043 0.0006 0.0027 0.0028 0.0038 0.001 0.0079 0.0011 0.0081 0.01 0.0163 0.0017 0.0029 0 0.0003 0.0023 0.0007 0.0004
Lipid Particles 0.0056 0.0003 0.0059 0.0038 0.0191 0.0013 0.0069 0.0008 0.0123 0.0127 0.0421 0.0038 0.0037 0 0.0002 0.0006 0.0009 0.0004
Mitochondria 0.0097 0.0002 0.0032 0.0059 0.0045 0.0029 0.0201 0.0004 0.0183 0.0114 0.0152 0.0043 0.0042 0.0002 0.0003 0.001 0.0008 0.003
None 0.0042 0.0028 0.0078 0.0011 0.0047 0.002 0.0158 0.0003 0.0004 0.0043 0.0005 0.0002 0.0068 0.0002 0.0002 0.0002 0.0007 0
Nuclear Periphery 0.0454 0.0048 0.0097 0.0173 0.0381 0.0125 0.0176 0.0028 0.0087 0.0038 0.0129 0.0039 0.0084 0.0103 0.0027 0.001 0.0093 0.0011
Nucleolus 0.0155 0.0123 0.0138 0.0115 0.0172 0.0163 0.0115 0.0062 0.01 0.0028 0.0115 0.0089 0.0065 0.006 0.0094 0.0026 0.0086 0.0099
Nucleus 0.7876 0.9352 0.9022 0.8878 0.8176 0.9265 0.7978 0.9728 0.8726 0.8709 0.8346 0.9557 0.9201 0.9802 0.9804 0.9254 0.9408 0.9777
Peroxisomes 0.0068 0.0009 0.0014 0.001 0.0016 0.0004 0.0034 0.0003 0.0077 0.0031 0.007 0.002 0.001 0 0.0001 0.0006 0.0005 0.0002
Punctate Nuclear 0.0173 0.0239 0.0118 0.0061 0.0275 0.0136 0.0135 0.0042 0.0039 0.0022 0.0088 0.0018 0.0084 0.0013 0.0009 0.0004 0.0146 0.0012
Vacuole 0.0037 0.0003 0.0042 0.0061 0.0027 0.0008 0.0039 0.0004 0.0013 0.0038 0.0012 0.0008 0.0007 0.0002 0.0002 0 0.0006 0.001
Vacuole Periphery 0.0025 0.0001 0.0021 0.0032 0.0026 0.0008 0.0021 0.0002 0.0009 0.0021 0.0013 0.0006 0.001 0.0002 0.0001 0.0001 0.0003 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.0323 9.4927 8.9651 8.9331 6.2581 9.6482 13.3064 10.306 11.6815 9.1355
Translational Efficiency 0.7822 0.9539 0.8977 0.9061 1.4066 1.0072 0.8321 0.927 0.7579 1.0184

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
927 188 182 979 1436 1547 66 969 2363 1735 248 1948

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 718.56 879.94 989.64 882.22 763.66 812.42 961.23 927.93 745.97 819.74 982.08 904.96
Standard Deviation 105.16 348.17 102.22 128.68 96.28 108.25 133.49 130.50 102.26 155.00 112.11 131.59
Intensity Change Log 2 — 0.292297 0.461795 0.296030 — 0.089295 0.331951 0.281086 — 0.191277 0.396358 0.288350

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000224 0.000757 0.001339 0.000760 0.000169 0.000233 0.001091 0.000681 0.000191 0.000290 0.001273 0.000721
Bud Neck 0.003893 0.012637 0.006537 0.018906 0.004117 0.004206 0.004222 0.018626 0.004029 0.005120 0.005921 0.018766
Bud Site 0.000779 0.003694 0.001713 0.005479 0.000910 0.001661 0.000804 0.003925 0.000858 0.001881 0.001471 0.004706
Cell Periphery 0.000174 0.000158 0.000137 0.000141 0.000117 0.000128 0.000070 0.000156 0.000139 0.000132 0.000119 0.000148
Cytoplasm 0.018982 0.008633 0.003031 0.020801 0.018432 0.010194 0.003725 0.020653 0.018648 0.010025 0.003216 0.020728
Cytoplasmic Foci 0.001718 0.007076 0.000187 0.000828 0.001515 0.001486 0.000126 0.000315 0.001594 0.002092 0.000171 0.000573
Eisosomes 0.000021 0.000034 0.000057 0.000026 0.000018 0.000016 0.000038 0.000025 0.000019 0.000018 0.000052 0.000026
Endoplasmic Reticulum 0.003366 0.009514 0.011652 0.009859 0.003192 0.003287 0.007564 0.008387 0.003260 0.003962 0.010564 0.009127
Endosome 0.000745 0.001818 0.000598 0.003112 0.000602 0.002378 0.000269 0.001476 0.000659 0.002318 0.000510 0.002298
Golgi 0.000541 0.003945 0.000094 0.000894 0.000205 0.000449 0.000076 0.000658 0.000337 0.000828 0.000089 0.000777
Lipid Particles 0.001107 0.000653 0.000517 0.000582 0.000652 0.000771 0.000351 0.000397 0.000831 0.000758 0.000473 0.000490
Mitochondria 0.000944 0.001814 0.001030 0.005960 0.001526 0.002305 0.000802 0.006836 0.001298 0.002252 0.000969 0.006396
Mitotic Spindle 0.000664 0.008734 0.000264 0.013387 0.000714 0.004070 0.000098 0.009955 0.000695 0.004576 0.000220 0.011680
None 0.013055 0.004748 0.003538 0.010441 0.004057 0.004439 0.001056 0.005452 0.007587 0.004472 0.002877 0.007960
Nuclear Periphery 0.000940 0.001002 0.000667 0.002634 0.001824 0.001494 0.000462 0.002448 0.001477 0.001441 0.000612 0.002541
Nuclear Periphery Foci 0.000731 0.000522 0.000328 0.001981 0.000702 0.000411 0.000374 0.000702 0.000713 0.000423 0.000340 0.001345
Nucleolus 0.014778 0.010998 0.006149 0.003735 0.012047 0.007659 0.006221 0.002561 0.013119 0.008021 0.006168 0.003151
Nucleus 0.935965 0.918456 0.952474 0.887567 0.946308 0.950625 0.969026 0.901321 0.942250 0.947140 0.956879 0.894409
Peroxisomes 0.000411 0.000693 0.000430 0.000326 0.000736 0.000509 0.000396 0.000166 0.000609 0.000529 0.000421 0.000246
Vacuole 0.000800 0.003476 0.009071 0.009080 0.001879 0.002457 0.003057 0.012202 0.001455 0.002568 0.007470 0.010633
Vacuole Periphery 0.000162 0.000636 0.000186 0.003500 0.000279 0.001219 0.000172 0.003057 0.000233 0.001156 0.000182 0.003280

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.50 -8.39 -11.78 -0.67 4.82 -1.74 -5.24 -12.46 -11.61 1.78 -3.49 -9.87 -17.13 -13.74 5.03
Bud Neck -3.96 -4.93 -10.47 -2.07 -6.86 -0.26 -2.24 -9.83 -9.58 -4.09 -2.18 -5.46 -14.41 -12.53 -8.31
Bud Site -2.21 -5.07 -4.77 -0.59 -2.96 -1.11 -1.77 -5.35 -3.36 -3.87 -1.81 -5.22 -6.91 -3.91 -4.31
Cell Periphery 0.27 0.69 1.43 1.00 0.49 -0.29 1.68 -0.94 -0.36 -2.36 0.32 0.35 0.25 -0.19 -0.19
Cytoplasm 3.14 6.00 -0.64 -4.22 -8.21 3.63 7.32 0.50 -3.16 -6.96 4.50 9.73 -0.28 -5.06 -10.90
Cytoplasmic Foci -1.46 3.84 2.71 1.77 -1.90 0.22 5.39 4.76 2.99 -3.43 -0.74 6.16 4.99 3.01 -2.09
Eisosomes -3.72 -6.68 -5.34 0.50 5.26 2.03 -4.43 -9.07 -11.61 1.68 1.72 -7.83 -10.40 -12.24 5.36
Endoplasmic Reticulum -4.72 -9.16 -10.04 -0.42 2.45 -0.20 -4.27 -12.70 -13.74 -1.21 -2.49 -10.09 -15.84 -14.41 1.59
Endosome -1.48 -0.26 -2.05 0.01 -2.08 -2.64 2.80 -2.22 1.64 -3.37 -2.75 -0.22 -2.84 0.98 -2.80
Golgi -1.11 0.84 -0.01 1.12 -1.72 -1.20 1.45 -0.66 0.35 -1.27 -1.17 1.08 -0.46 0.93 -2.02
Lipid Particles 1.03 0.73 1.16 0.07 0.84 -0.39 2.19 1.10 1.13 -1.67 0.33 0.81 1.43 0.89 0.80
Mitochondria -1.56 -1.73 -3.18 -2.01 -2.89 -1.10 0.95 -2.25 -1.63 -2.72 -1.71 0.18 -3.63 -2.31 -3.89
Mitotic Spindle -1.37 -0.72 -5.41 -1.50 -5.20 -2.61 2.58 -4.37 -2.78 -4.64 -2.98 -0.29 -6.95 -4.30 -6.77
None 3.29 4.26 2.03 -1.56 -2.66 -0.44 6.23 -0.29 0.20 -5.60 2.81 4.21 1.28 -1.54 -3.14
Nuclear Periphery -0.99 0.30 -5.36 -3.43 -5.72 0.59 4.12 -4.39 -3.35 -10.37 0.08 3.50 -6.19 -3.30 -10.56
Nuclear Periphery Foci 0.40 0.28 -1.58 -1.80 -1.76 1.48 1.68 -0.15 -2.64 -2.55 1.80 1.00 -1.36 -2.99 -2.29
Nucleolus 1.20 2.17 5.46 3.14 2.05 2.97 3.02 7.38 5.20 1.24 4.01 2.68 8.74 4.76 2.66
Nucleus 1.65 -0.11 6.60 2.22 5.95 -0.91 -1.97 8.53 8.92 8.58 -1.04 -0.08 10.94 10.85 8.53
Peroxisomes -1.14 -1.45 1.59 1.84 2.62 0.67 0.94 1.74 3.00 1.73 0.40 0.15 1.96 2.88 3.42
Vacuole -2.50 -3.69 -7.50 -4.14 -0.11 -0.80 -2.04 -8.67 -8.46 -6.05 -2.09 -3.83 -11.25 -10.19 -2.39
Vacuole Periphery -1.73 -1.20 -2.50 -1.73 -2.40 -2.44 1.41 -1.86 -0.28 -2.06 -2.70 0.34 -3.09 -0.94 -3.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of a complex with Ctf8p and Ctf18p; shares some components with Replication Factor C; required for sister chromatid cohesion and telomere length maintenance
Localization
Cell Percentages nucleus (97%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Dcc1

Dcc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dcc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available