Standard name
Human Ortholog
Description Transcription factor required for response to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0.07 0.06 0.06
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Cytoplasm 0.37 0.4 0.68 0.37 0.69 0.83 0.77 0.76 0.6 0.72 0.48 0.56 0.4 0.45 0.62 0.89 0.91 0.89 0.29 0.26 0.61 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0.1 0.06 0 0 0 0 0 0 0 0.06 0.12 0.05 0 0 0 0.08 0.06 0 0 0 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Mitochondria 0.06 0 0 0 0 0.13 0.27 0.25 0.48 0.43 0.61 0.52 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.16 0.11 0.13 0.18 0 0 0 0.05 0.06 0.05 0.05 0 0.24 0.09 0.1 0 0 0 0.29 0.31 0.19 0.62 0.43 0.37
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0.14 0.19 0.15
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0.06 0 0.05 0.05
Vac/Vac Membrane 0.45 0.5 0.25 0.48 0.3 0.07 0.06 0.06 0 0 0 0.06 0.39 0.49 0.32 0.1 0.11 0.05 0.1 0.11 0 0.1 0.16 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 2 1 1 0 0 0 1
Bud 0 0 0 0 0 0 3 7 1 2 2 5 0 0 0 0 0 1 10 8 1 22 29 22
Bud Neck 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 3
Bud Site 0 0 0 0 0 0 1 1 2 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 1 0 0 2 0 0 0 0 0 0 11 1 14 0 0 0 0 0 0
Cytoplasm 55 42 51 33 144 189 218 242 64 131 88 101 98 180 238 263 58 209 54 33 64 7 9 10
Endoplasmic Reticulum 0 2 1 0 0 0 0 0 0 2 2 3 2 2 3 10 3 5 1 0 0 0 4 4
Endosome 4 2 2 9 13 6 2 0 0 0 0 1 14 49 21 4 1 8 14 7 2 3 12 27
Golgi 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 3 1 2 0 0 0 0 12 21
Mitochondria 9 1 0 1 4 29 77 80 51 78 112 93 0 0 2 3 2 1 1 0 1 1 2 4
Nucleus 23 12 10 16 9 5 7 15 6 9 9 6 58 36 38 3 1 1 54 41 20 212 199 151
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 2 4
Nucleolus 1 4 1 0 1 1 2 0 1 0 0 1 2 1 0 2 1 2 8 11 1 47 85 59
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 2 0 0 0 1 0 1 0 0 3 0 2 16 8 5 5 20 21
Vac/Vac Membrane 66 52 19 43 62 16 17 20 4 2 7 11 96 194 122 29 7 12 18 13 4 32 71 61
Unique Cell Count 148 105 75 90 209 229 283 318 107 181 185 180 246 398 384 295 64 234 189 132 106 341 460 409
Labelled Cell Count 158 115 84 102 237 247 330 365 131 224 222 222 271 463 424 331 75 259 189 132 106 341 460 409


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 8.4 7.2 7.0 6.7 5.1 4.6 4.7 4.0 3.9 3.7 3.7 8.7 8.3 7.7 8.1 8.0 8.2 23.4 22.0 22.8
Std Deviation (1e-4) 1.1 1.9 1.2 1.1 1.3 1.3 1.6 1.2 1.2 1.3 1.2 0.7 1.3 1.6 1.2 1.4 1.7 1.7 8.4 5.8 5.4
Intensity Change (Log2) – – – -0.05 -0.11 -0.5 -0.66 -0.63 -0.86 -0.88 -0.97 -0.98 0.27 0.19 0.09 0.16 0.15 0.17 1.69 1.6 1.65

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -4.0 0.1 2.7 1.6 1.4 -1.1 0.7 -3.0 -1.8 -4.3 -3.6 -1.0 4.6 3.2 4.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 1.9 0 0 0 0 0 0 0 0 0 2.5 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.8 -2.7 0 0 0 -1.8 -2.3 -2.4 0 1.9 -1.1 -0.9 0 -2.6 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.0 0.7 -4.3 -4.9 -5.0 -4.3 -6.4 -5.2 -4.3 2.2 3.7 1.1 -3.6 -2.2 -5.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5455 3.4544 3.0237 2.4597 2.9467 2.7504 3.9817 4.8722 4.1487 3.7885 3.5652 3.9105 3.1822 2.8991 2.5977 2.2627 3.7721 2.3829
Actin 0.016 0.0012 0.0031 0.001 0.0102 0.0013 0.023 0.001 0.0104 0.0223 0.0022 0.0014 0.0915 0.0004 0.0294 0.0178 0.0973 0.0581
Bud 0.001 0.0025 0.004 0.0018 0.0009 0.0012 0.0006 0.0006 0.0013 0.0018 0.0002 0.0021 0.0024 0.0003 0.002 0.0005 0.0074 0.0006
Bud Neck 0.0024 0.0012 0.0038 0.0038 0.0018 0.0045 0.0056 0.0015 0.0027 0.0122 0.0029 0.0046 0.0122 0.0005 0.0157 0.0019 0.0065 0.0034
Bud Periphery 0.0014 0.0007 0.0015 0.0017 0.0014 0.0007 0.0008 0.0003 0.0009 0.001 0.0001 0.0009 0.0035 0.0001 0.0021 0.0004 0.0102 0.0009
Bud Site 0.0079 0.0084 0.0122 0.0323 0.0009 0.0006 0.003 0.0039 0.0066 0.0023 0.0004 0.0005 0.0159 0.001 0.0149 0.0004 0.0726 0.0005
Cell Periphery 0.0004 0.0001 0.0002 0.0006 0.0001 0.0001 0.0002 0.0001 0.0001 0.0003 0.0001 0 0.0007 0 0.0006 0.0001 0.0013 0.0002
Cytoplasm 0.1594 0.3482 0.2766 0.1981 0.3071 0.3112 0.1495 0.2637 0.1693 0.1041 0.2011 0.2331 0.2086 0.5182 0.2984 0.2004 0.1804 0.3102
Cytoplasmic Foci 0.0204 0.0047 0.0073 0.0049 0.0228 0.0089 0.0146 0.0054 0.0041 0.0092 0.0035 0.0077 0.0589 0.0027 0.0071 0.0053 0.0224 0.0017
Eisosomes 0.0001 0 0 0 0 0 0.0002 0 0.0001 0.0002 0.0001 0 0.0017 0 0.0008 0 0.0006 0.0005
Endoplasmic Reticulum 0.0151 0.0041 0.0048 0.0023 0.0056 0.0032 0.0048 0.0028 0.0025 0.0031 0.0069 0.0015 0.0204 0.0029 0.0041 0.0111 0.0098 0.0063
Endosome 0.0549 0.0065 0.0139 0.0093 0.0371 0.0151 0.0243 0.0075 0.0095 0.011 0.0163 0.0029 0.0799 0.0019 0.0101 0.0127 0.042 0.0083
Golgi 0.0079 0.0002 0.0042 0.0011 0.016 0.0013 0.0054 0.0014 0.0027 0.0042 0.0008 0.0006 0.0176 0.0001 0.0042 0.0019 0.0134 0.0054
Lipid Particles 0.0059 0.0001 0.0014 0.0006 0.004 0.0057 0.009 0.0004 0.0028 0.005 0.0016 0.0016 0.0288 0 0.012 0.0006 0.0102 0.0008
Mitochondria 0.011 0.0009 0.0036 0.0017 0.0047 0.0013 0.0045 0.0012 0.0024 0.0028 0.0013 0.0007 0.0131 0.0004 0.0047 0.0012 0.0089 0.0315
None 0.0239 0.0424 0.0148 0.0087 0.007 0.0388 0.0061 0.009 0.0133 0.0088 0.0204 0.0075 0.0224 0.0112 0.0201 0.004 0.0053 0.0038
Nuclear Periphery 0.0482 0.0224 0.0262 0.0222 0.0242 0.0174 0.0176 0.0172 0.0167 0.02 0.0277 0.0105 0.0774 0.0189 0.0298 0.0227 0.0318 0.0324
Nucleolus 0.0032 0.0021 0.0029 0.0038 0.0035 0.0039 0.0028 0.0022 0.0032 0.0101 0.0057 0.0018 0.0098 0.0009 0.0021 0.0013 0.0039 0.0011
Nucleus 0.5711 0.5344 0.5832 0.6517 0.4299 0.5214 0.6898 0.6609 0.7195 0.7145 0.6586 0.6969 0.2504 0.4184 0.5033 0.7025 0.4372 0.5222
Peroxisomes 0.005 0.0002 0.001 0.0008 0.0067 0.0017 0.0065 0.0008 0.0018 0.0223 0.0005 0.0052 0.0369 0.0002 0.013 0.0005 0.0061 0.0003
Punctate Nuclear 0.0319 0.0155 0.0299 0.0452 0.1022 0.0559 0.0271 0.0168 0.0261 0.0364 0.0469 0.0193 0.0369 0.0195 0.0213 0.0107 0.0209 0.0073
Vacuole 0.0089 0.0034 0.0045 0.0072 0.0088 0.0045 0.0036 0.0029 0.0031 0.0077 0.002 0.0011 0.0069 0.002 0.0032 0.0032 0.0089 0.0031
Vacuole Periphery 0.0038 0.0007 0.0009 0.0009 0.0052 0.0014 0.0011 0.0005 0.0007 0.0009 0.0008 0.0002 0.0042 0.0003 0.0012 0.0009 0.0029 0.0016

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.967 23.4851 14.5225 19.9639 26.2563 30.6332 15.3358 15.359 15.8603 23.1042
Translational Efficiency 1.6519 1.1738 1.2918 1.2863 1.3425 1.1396 1.6232 1.3184 1.4875 1.273

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
988 1045 2412 587 1931 2212 1729 162 2919 3257 4141 749

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 839.88 951.36 1040.96 1020.69 793.42 929.70 1010.10 989.91 809.15 936.65 1028.07 1014.03
Standard Deviation 116.11 153.50 150.64 157.35 100.32 133.82 164.40 143.71 108.19 140.80 157.27 155.02
Intensity Change Log 2 — 0.179808 0.309660 0.281290 — 0.228680 0.348341 0.319213 — 0.203756 0.328580 0.299836

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000239 0.000988 0.000195 0.001397 0.000083 0.000372 0.000150 0.000996 0.000136 0.000569 0.000176 0.001310
Bud Neck 0.002383 0.007552 0.009275 0.006006 0.003913 0.012369 0.007459 0.004808 0.003395 0.010824 0.008516 0.005747
Bud Site 0.001330 0.004465 0.002213 0.007952 0.002363 0.004792 0.002423 0.006157 0.002013 0.004687 0.002301 0.007564
Cell Periphery 0.000147 0.000204 0.000087 0.000222 0.000121 0.000112 0.000573 0.000209 0.000130 0.000141 0.000290 0.000219
Cytoplasm 0.430799 0.326904 0.281646 0.249940 0.399996 0.300616 0.363213 0.248029 0.410421 0.309050 0.315703 0.249527
Cytoplasmic Foci 0.056762 0.019807 0.001444 0.007750 0.031188 0.015860 0.010126 0.008572 0.039844 0.017126 0.005069 0.007928
Eisosomes 0.000051 0.000039 0.000009 0.000038 0.000031 0.000022 0.000243 0.000062 0.000038 0.000027 0.000106 0.000043
Endoplasmic Reticulum 0.003172 0.005909 0.001925 0.009884 0.001265 0.002858 0.001412 0.010868 0.001910 0.003837 0.001711 0.010097
Endosome 0.002999 0.004274 0.000695 0.005156 0.002040 0.003575 0.000789 0.002842 0.002365 0.003799 0.000735 0.004656
Golgi 0.000533 0.002069 0.000166 0.001267 0.000105 0.001435 0.000093 0.000136 0.000250 0.001638 0.000136 0.001022
Lipid Particles 0.004558 0.002742 0.000237 0.001387 0.001905 0.001141 0.000907 0.002102 0.002803 0.001655 0.000517 0.001542
Mitochondria 0.002255 0.003225 0.001620 0.001519 0.000944 0.004280 0.000775 0.000513 0.001388 0.003942 0.001267 0.001301
Mitotic Spindle 0.001320 0.014945 0.018097 0.022507 0.001216 0.016509 0.014596 0.008657 0.001251 0.016008 0.016635 0.019511
None 0.008668 0.017542 0.011214 0.006346 0.009870 0.010448 0.015927 0.004666 0.009463 0.012724 0.013182 0.005983
Nuclear Periphery 0.002294 0.002105 0.003027 0.002792 0.001847 0.002445 0.001407 0.002101 0.001998 0.002336 0.002351 0.002642
Nuclear Periphery Foci 0.005316 0.008263 0.000398 0.005710 0.000866 0.002786 0.000500 0.005627 0.002372 0.004543 0.000441 0.005692
Nucleolus 0.003696 0.009989 0.000960 0.000600 0.003528 0.007736 0.001214 0.000608 0.003585 0.008459 0.001066 0.000602
Nucleus 0.451027 0.548353 0.657332 0.598451 0.524649 0.597330 0.558740 0.611310 0.499730 0.581616 0.616167 0.601232
Peroxisomes 0.000927 0.001310 0.000069 0.000620 0.000512 0.001848 0.000576 0.000563 0.000652 0.001675 0.000281 0.000608
Vacuole 0.021216 0.018825 0.009274 0.067134 0.013386 0.012870 0.018756 0.080978 0.016036 0.014781 0.013233 0.070128
Vacuole Periphery 0.000308 0.000492 0.000117 0.003323 0.000173 0.000596 0.000121 0.000195 0.000219 0.000563 0.000118 0.002647

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -8.10 -1.37 -7.17 -1.06 -6.97 -8.26 -8.28 -8.10 -5.61 -6.59 -11.22 -8.13 -9.65 -5.24 -8.40
Bud Neck -8.66 -17.18 -8.40 -0.65 3.22 -11.22 -5.25 -1.71 4.36 1.51 -13.95 -14.23 -7.03 2.87 2.60
Bud Site -8.23 -4.52 -6.70 -3.57 -5.72 -2.85 -1.35 -2.50 -1.88 -2.21 -5.02 -1.88 -6.23 -4.16 -5.73
Cell Periphery -3.32 6.14 -5.65 -2.69 -11.55 1.18 -4.13 -5.23 -5.74 1.41 -1.19 -2.53 -9.03 -8.54 -2.87
Cytoplasm 9.23 21.47 18.10 8.58 0.39 12.55 11.96 10.20 3.80 3.96 15.63 25.34 22.21 9.80 4.24
Cytoplasmic Foci 10.51 16.90 14.67 6.07 -5.95 8.06 14.13 7.09 1.69 -1.90 13.02 22.84 17.84 6.71 -4.70
Eisosomes 2.44 12.27 1.53 -1.04 -13.34 3.75 -3.16 -6.31 -7.26 1.41 4.44 -1.55 -5.38 -8.65 0.15
Endoplasmic Reticulum -6.64 0.60 -10.32 -5.18 -11.93 -10.03 -8.30 -9.47 -7.76 -7.98 -10.91 -6.01 -15.82 -11.44 -14.25
Endosome -1.22 9.98 -0.22 0.71 -4.11 -2.27 4.11 -3.83 -1.85 -6.21 -2.51 8.55 -2.06 -0.38 -5.25
Golgi -1.87 2.15 -0.03 1.69 -1.27 -3.54 0.38 -3.27 3.21 -3.55 -3.81 1.99 -0.85 2.28 -1.39
Lipid Particles 3.80 9.91 5.70 1.38 -12.64 4.20 6.36 -2.17 -4.50 -5.57 5.61 12.40 2.77 -3.48 -12.64
Mitochondria -0.57 -0.12 0.78 1.73 6.45 -5.04 -1.23 1.55 6.38 9.28 -3.78 -1.32 0.41 5.16 6.32
Mitotic Spindle -5.64 -11.03 -5.57 -2.64 -0.93 -7.72 -7.98 -2.29 -0.72 -0.23 -9.53 -13.63 -6.02 -2.68 -1.12
None -5.00 -3.42 3.49 8.48 11.73 -0.73 -2.17 7.51 8.85 7.71 -3.71 -3.77 7.15 11.18 11.94
Nuclear Periphery -0.60 -7.81 -4.85 -5.11 2.76 -3.88 -5.29 -2.98 0.03 0.04 -3.57 -11.35 -7.54 -4.20 1.03
Nuclear Periphery Foci -2.19 4.70 -0.89 1.65 -8.16 -3.32 1.77 -3.18 -2.49 -3.37 -3.53 5.14 -5.08 -2.52 -8.13
Nucleolus -6.06 3.17 6.23 10.29 6.15 -6.72 4.89 7.35 11.83 2.36 -8.86 5.42 9.25 15.25 5.83
Nucleus -7.35 -23.69 -7.20 -0.66 11.20 -8.12 -9.15 -0.28 2.99 3.47 -10.96 -23.92 -4.60 2.59 9.92
Peroxisomes -0.65 7.84 4.31 4.06 -3.49 -2.39 0.74 -0.74 0.83 -0.96 -2.44 5.18 1.39 2.95 -2.02
Vacuole -0.57 4.25 -13.61 -13.29 -15.02 -0.62 -7.79 -9.23 -9.17 -7.98 -0.70 -3.28 -17.16 -17.01 -16.49
Vacuole Periphery -2.32 4.67 -0.94 -0.77 -1.17 -4.31 1.55 -1.68 3.69 -2.70 -4.81 4.90 -1.04 -0.65 -1.19
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcription factor required for response to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone
Localization
Cell Percentages nucleus (36%), cytoplasm (15%), mixed (45%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Kar4

Kar4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kar4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available