ORF
Human Ortholog
Description Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.08 0.08 0.13 0.49 0.5 0.62 0.59 0.61 0.69 0.63 0.65 0.6 0.17 0.13 0.13 0.29 0.24 0.21 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.06 0.05 0.24 0.2 0.19 0.06 0 0.05 0.05 0 0 0 0.12 0.09 0.07 0.13 0.06 0.08 0.08 0.11 0.08 0.12 0.12 0.13
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.07 0.16 0.1 0.37 0.48 0.39 0.39 0.52 0.48 0.47 0 0 0 0.05 0.09 0 0 0 0 0 0 0
Nucleus 0.09 0.07 0 0 0 0 0 0 0 0 0 0 0.07 0.11 0.13 0 0.12 0.07 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.84 0.84 0.8 0.41 0.5 0.28 0.19 0.18 0.15 0.15 0.14 0.21 0.76 0.8 0.79 0.61 0.68 0.74 0.82 0.73 0.78 0.77 0.77 0.73
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 1 0 0 0 0 1 0 0 2
Bud 0 0 1 3 0 3 6 14 15 7 9 14 2 1 0 1 0 0 0 0 0 1 1 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 0 1 0 0 1 7 6 2 6 10 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 27 15 46 168 183 318 378 486 336 364 399 415 120 94 106 86 48 26 2 2 5 2 3 4
Endoplasmic Reticulum 3 1 0 1 1 1 2 10 3 3 1 4 19 7 14 10 9 5 0 0 2 1 1 1
Endosome 18 9 87 69 70 31 20 38 23 10 11 30 87 66 55 39 12 10 27 22 32 27 47 49
Golgi 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 5 0 2 2 1 1
Mitochondria 14 7 26 55 36 191 308 314 193 301 295 326 2 1 0 14 19 4 3 2 7 6 7 14
Nucleus 28 12 5 0 5 8 4 3 4 2 2 7 52 79 106 12 24 9 7 7 2 2 6 4
Nuclear Periphery 1 8 4 0 1 0 4 2 1 0 0 0 2 1 3 5 5 1 7 11 26 8 16 10
Nucleolus 5 3 7 1 0 0 1 2 0 0 0 1 0 1 1 1 0 0 0 3 0 1 0 1
Peroxisomes 0 0 1 0 0 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 1 0 3 3 1 2 1 1 1 0 0 3 4 5 2 3 0 0 0 0 0 0 0 1
Vac/Vac Membrane 267 154 287 141 183 144 125 146 74 89 87 144 551 590 636 179 138 93 278 149 305 186 305 275
Unique Cell Count 318 183 360 341 368 515 645 797 490 575 615 689 724 738 808 292 204 125 339 206 392 242 397 378
Labelled Cell Count 366 209 468 442 480 698 851 1024 656 778 810 955 840 848 926 351 255 148 339 206 392 242 397 378


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 6.7 5.8 5.4 5.4 4.5 4.2 4.5 4.8 4.1 4.5 4.5 6.6 7.1 7.3 5.7 6.2 7.0 7.0 7.1 7.3
Std Deviation (1e-4) 1.0 1.2 1.4 1.3 1.5 1.4 1.1 1.1 2.2 0.8 1.2 0.9 0.9 0.9 0.9 1.2 1.3 1.5 1.8 1.6 1.7
Intensity Change (Log2) – – – -0.11 -0.12 -0.39 -0.46 -0.37 -0.28 -0.49 -0.38 -0.37 0.19 0.28 0.33 -0.02 0.09 0.27 0.28 0.29 0.32

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 10.5 10.7 14.5 14.1 15.2 16.2 15.2 15.8 14.7 1.6 0 0.2 5.3 3.3 2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 3.1 0 0 0 0 0
Endosome -1.3 -1.7 0 0 0 0 0 0 0 -5.1 -6.8 -8.4 -3.5 -5.5 -3.9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.7 1.2 0 0 0 0 0 0 0 -6.8 -7.1 -7.7 -1.3 0.9 -1.6
Nucleus 0 0 0.2 0 0 0 0 0 0 4.0 5.5 6.3 2.2 5.4 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -10.4 -8.5 -15.1 -18.6 -20.0 -18.8 -19.5 -20.3 -18.4 -1.3 0.1 -0.4 -5.2 -3.2 -1.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9221 2.196 2.3049 2.2586 2.6724 2.3056 3.2299 3.4947 3.087 3.6814 2.9873 3.086 3.9115 4.1633 3.9678 3.8879 3.7497 4.1703
Actin 0.0019 0.0001 0.0019 0.0182 0.0032 0.0011 0.0061 0.0001 0.0001 0.0087 0 0.0163 0.0055 0.0001 0.0004 0.0003 0 0
Bud 0.0004 0.0042 0.0015 0.0027 0.0021 0.0012 0.0008 0.0001 0.0016 0.0002 0.0005 0.0004 0.0003 0.0016 0.002 0.002 0.0006 0.0008
Bud Neck 0.0011 0.0007 0.0008 0.0019 0.0003 0.0021 0.012 0.0002 0.0002 0.0001 0.0002 0.0007 0.0005 0.0008 0.0025 0.0008 0.0003 0.0011
Bud Periphery 0.0012 0.0033 0.0017 0.0036 0.0031 0.0015 0.0011 0.0002 0.0026 0.0003 0.0003 0.0006 0.0005 0.0011 0.0039 0.0028 0.0009 0.0015
Bud Site 0.0014 0.0072 0.0024 0.0187 0.0108 0.0014 0.0104 0.0007 0.0024 0.0003 0.0025 0.0004 0.0008 0.0058 0.0068 0.0012 0.0006 0.0009
Cell Periphery 0.003 0.0004 0.0003 0.0009 0.0007 0.0004 0.0012 0.0004 0.0005 0.0001 0.0002 0.0003 0.0089 0.0201 0.0082 0.0194 0.0003 0.0144
Cytoplasm 0.0219 0.1375 0.1261 0.0637 0.0691 0.0686 0.0767 0.0921 0.1335 0.0098 0.1633 0.1213 0.0695 0.0952 0.1029 0.1083 0.0449 0.0728
Cytoplasmic Foci 0.0226 0.0262 0.042 0.0403 0.026 0.0312 0.0436 0.055 0.0272 0.03 0.0384 0.0226 0.0302 0.0192 0.0324 0.0362 0.0158 0.0241
Eisosomes 0.0003 0 0 0.0002 0.0001 0 0.0001 0.0001 0 0 0 0.0001 0.0001 0.0001 0 0 0 0
Endoplasmic Reticulum 0.0065 0.0066 0.0094 0.0016 0.004 0.005 0.0211 0.0089 0.0102 0.0016 0.0031 0.0083 0.0099 0.0077 0.0129 0.0023 0.0061 0.0058
Endosome 0.3395 0.2494 0.3378 0.3444 0.2845 0.3237 0.268 0.3404 0.3872 0.3199 0.4952 0.2663 0.3782 0.2902 0.3631 0.3602 0.4001 0.3071
Golgi 0.0078 0.0021 0.0063 0.0153 0.022 0.0062 0.0115 0.0024 0.0067 0.0043 0.0062 0.0055 0.0045 0.0029 0.0072 0.0117 0.0044 0.0036
Lipid Particles 0.0089 0.0021 0.0077 0.0106 0.027 0.0052 0.0166 0.0076 0.0037 0.0068 0.0018 0.0049 0.0058 0.0045 0.0025 0.0008 0.0029 0.0033
Mitochondria 0.0181 0.004 0.012 0.046 0.0586 0.0048 0.0085 0.0051 0.0097 0.003 0.0018 0.0048 0.0058 0.0027 0.0203 0.0056 0.0016 0.0038
None 0.0105 0.0988 0.0525 0.0084 0.1057 0.011 0.014 0.1217 0.0155 0.0008 0.0095 0.1157 0.0323 0.0336 0.0238 0.0105 0.0216 0.0572
Nuclear Periphery 0.027 0.012 0.0188 0.0034 0.016 0.0121 0.0608 0.0142 0.0182 0.0053 0.0039 0.0122 0.0099 0.018 0.0183 0.004 0.0083 0.0132
Nucleolus 0.0053 0.0029 0.0028 0.0049 0.0009 0.0045 0.0031 0.0017 0.0007 0.0003 0.0009 0.0008 0.0016 0.0079 0.0016 0.0005 0.0005 0.0009
Nucleus 0.0356 0.011 0.0173 0.0072 0.0027 0.02 0.0549 0.0054 0.0053 0.0012 0.0039 0.0053 0.0079 0.0105 0.0059 0.0033 0.0017 0.005
Peroxisomes 0.0043 0.0004 0.0145 0.0076 0.0059 0.0008 0.0297 0.0006 0.0005 0.1286 0.0005 0.0022 0.0004 0.0004 0.0011 0.0005 0.0005 0.0005
Punctate Nuclear 0.0033 0.0011 0.0046 0.0022 0.0019 0.0015 0.0018 0.0013 0.0004 0.0005 0.001 0.0005 0.0009 0.0006 0.0007 0.0002 0.0002 0.0004
Vacuole 0.4033 0.3691 0.2798 0.3207 0.2603 0.405 0.3218 0.2935 0.3038 0.3279 0.2332 0.3088 0.3546 0.4001 0.3059 0.3506 0.3882 0.3787
Vacuole Periphery 0.0763 0.0607 0.0595 0.0776 0.0951 0.0927 0.036 0.0484 0.07 0.1503 0.0335 0.1018 0.0719 0.0768 0.0776 0.0788 0.1003 0.1048

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.527 11.2821 10.3651 16.0359 19.48 6.0065 22.4072 24.7473 20.86 24.0273
Translational Efficiency 0.271 0.4904 0.4438 0.2362 0.2489 0.9277 0.2934 0.2201 0.2193 0.2784

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
125 881 1751 435 2059 1923 1654 1462 2184 2804 3405 1897

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 899.13 847.13 947.17 923.59 783.15 857.89 789.72 860.93 789.79 854.51 870.69 875.30
Standard Deviation 160.45 126.20 126.81 109.30 98.30 113.01 140.22 115.62 106.35 117.42 154.96 117.20
Intensity Change Log 2 — -0.085946 0.075094 0.038723 — 0.131504 0.012053 0.136607 — 0.019371 0.046089 0.085118

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000551 0.000066 0.000085 0.000270 0.000022 0.000037 0.000116 0.000437 0.000052 0.000046 0.000100 0.000399
Bud Neck 0.006496 0.004457 0.008091 0.010742 0.003890 0.003959 0.015952 0.012158 0.004039 0.004116 0.011909 0.011833
Bud Site 0.036358 0.010211 0.005859 0.028443 0.004390 0.006475 0.009737 0.022363 0.006219 0.007649 0.007743 0.023757
Cell Periphery 0.000214 0.000151 0.000067 0.000050 0.000150 0.000139 0.000062 0.000104 0.000154 0.000143 0.000064 0.000091
Cytoplasm 0.181705 0.020115 0.016581 0.308324 0.029053 0.013695 0.333917 0.388422 0.037790 0.015712 0.170729 0.370055
Cytoplasmic Foci 0.093973 0.034836 0.008937 0.042540 0.034002 0.035729 0.022225 0.053020 0.037435 0.035449 0.015392 0.050617
Eisosomes 0.000092 0.000016 0.000019 0.000028 0.000014 0.000017 0.000025 0.000038 0.000019 0.000016 0.000022 0.000036
Endoplasmic Reticulum 0.002641 0.004771 0.004830 0.002065 0.010735 0.006407 0.004403 0.001844 0.010272 0.005893 0.004623 0.001895
Endosome 0.043550 0.105264 0.042474 0.024504 0.086437 0.123072 0.027615 0.024715 0.083982 0.117477 0.035256 0.024667
Golgi 0.020750 0.005957 0.003036 0.001767 0.002305 0.006833 0.000576 0.003677 0.003360 0.006558 0.001841 0.003239
Lipid Particles 0.004450 0.002921 0.001464 0.001683 0.003548 0.003713 0.002164 0.002584 0.003600 0.003464 0.001804 0.002377
Mitochondria 0.004666 0.005457 0.003046 0.000877 0.006222 0.013031 0.001553 0.003756 0.006133 0.010651 0.002321 0.003096
Mitotic Spindle 0.001476 0.004493 0.006751 0.019032 0.000674 0.002255 0.007339 0.020036 0.000720 0.002958 0.007037 0.019806
None 0.000222 0.000277 0.000895 0.001447 0.000379 0.000265 0.003180 0.002137 0.000370 0.000268 0.002005 0.001979
Nuclear Periphery 0.000932 0.000987 0.004529 0.001694 0.000734 0.001206 0.003888 0.001532 0.000745 0.001138 0.004218 0.001569
Nuclear Periphery Foci 0.001593 0.001779 0.002854 0.002546 0.000278 0.000698 0.001842 0.001582 0.000353 0.001038 0.002363 0.001803
Nucleolus 0.000741 0.001326 0.012786 0.000948 0.000694 0.000917 0.010660 0.001033 0.000697 0.001046 0.011753 0.001013
Nucleus 0.086446 0.003636 0.039002 0.058510 0.005117 0.002809 0.186307 0.066869 0.009772 0.003069 0.110557 0.064952
Peroxisomes 0.002697 0.002273 0.001331 0.005311 0.000632 0.001043 0.000902 0.001640 0.000750 0.001429 0.001123 0.002482
Vacuole 0.485415 0.489812 0.528283 0.487242 0.649123 0.472711 0.359087 0.388158 0.639753 0.478084 0.446095 0.410879
Vacuole Periphery 0.025032 0.301195 0.309079 0.001977 0.161602 0.304989 0.008448 0.003895 0.153785 0.303797 0.163046 0.003455

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.86 1.75 1.19 -3.40 -2.87 -1.60 -8.20 -2.77 -2.61 -1.66 0.05 -3.96 -2.93 -2.97 -2.15
Bud Neck 0.87 -1.85 -1.81 -3.30 -0.29 -0.11 -10.20 -6.21 -5.89 4.21 -0.23 -10.50 -6.83 -6.68 2.38
Bud Site 2.20 2.61 1.66 -1.33 -2.58 -2.47 -3.86 -6.72 -5.16 -3.60 -1.76 -1.53 -5.85 -4.96 -5.15
Cell Periphery 0.60 2.59 3.05 6.21 3.64 0.42 4.51 3.28 3.42 -2.16 0.38 4.58 3.96 5.26 -1.11
Cytoplasm 8.17 8.30 -6.07 -22.83 -23.14 7.36 -40.93 -46.18 -49.06 -3.80 9.17 -26.87 -48.41 -53.69 -24.10
Cytoplasmic Foci 5.13 8.27 5.58 1.23 -8.18 -0.83 7.09 -3.66 -2.68 -10.79 0.55 13.41 -1.36 -2.01 -16.05
Eisosomes 7.88 7.62 6.35 -5.49 -5.03 -0.66 -8.00 -12.84 -5.19 -5.79 0.75 -2.87 -10.12 -6.75 -8.51
Endoplasmic Reticulum -2.49 -4.28 0.95 3.46 8.57 4.20 7.57 10.79 7.61 10.76 4.73 7.07 10.78 8.33 13.78
Endosome -9.93 -1.33 4.55 17.03 11.60 -7.61 20.88 23.90 26.00 4.59 -8.28 17.57 24.69 30.92 12.03
Golgi 1.12 1.46 1.73 5.41 4.29 -6.40 5.34 0.53 5.57 -2.35 -4.51 2.13 1.87 7.00 0.28
Lipid Particles 1.00 2.86 2.70 2.40 -0.83 -0.29 3.57 3.03 2.73 -0.18 0.11 4.34 3.60 3.30 -1.02
Mitochondria -0.88 0.18 1.44 7.52 8.55 -5.03 6.63 4.39 8.42 -1.28 -4.31 5.36 5.22 9.50 1.10
Mitotic Spindle -2.36 -4.58 -4.34 -3.09 -2.52 -2.22 -5.14 -6.95 -6.03 -3.33 -3.51 -7.54 -8.18 -6.63 -4.27
None -0.83 -2.02 -5.91 -5.51 -2.25 0.53 -8.12 -3.61 -4.36 2.07 0.49 -5.28 -4.36 -5.45 -0.20
Nuclear Periphery -0.20 -6.23 -5.73 -5.10 3.86 -2.46 -7.68 -6.63 -2.95 5.06 -2.52 -9.76 -8.23 -4.73 6.43
Nuclear Periphery Foci -0.19 -2.33 -3.11 -1.59 0.34 -3.23 -8.42 -9.78 -4.82 2.72 -3.01 -7.32 -12.05 -3.24 2.52
Nucleolus -2.27 -11.45 -2.06 1.14 11.10 -1.43 -9.28 -1.83 -0.07 9.04 -2.37 -14.65 -2.21 0.80 14.35
Nucleus 5.43 2.79 0.06 -14.88 -6.83 3.22 -35.53 -25.82 -27.00 18.54 5.73 -31.23 -26.32 -30.78 8.18
Peroxisomes -0.07 1.65 0.05 0.09 -0.63 -2.10 -2.12 -3.01 -0.14 -1.85 -2.46 -3.04 -1.98 0.26 -0.74
Vacuole 1.63 0.30 0.91 -1.10 1.25 22.41 32.35 24.14 5.15 -6.50 23.02 27.29 23.06 4.22 0.10
Vacuole Periphery -22.78 -25.36 1.96 36.60 47.33 -21.70 41.00 42.30 55.55 7.40 -25.83 -1.19 41.46 66.47 37.74
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene
Localization
Cell Percentages vacuolar membrane (56%), vacuole (8%), mixed (28%)
Cell Cycle Regulation No
Subcompartmental Group N/A

YCR023C

YCR023C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ycr023c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available