Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0.05 0.12 0.08 0.14 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 – 0 0 0 0 0 0 0 0 0.07 0.09 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.05 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0.05 0 0 0 0.05 0.05 0 0
Golgi 0.06 0.11 0 0 0 0 – 0 0 0 0 0 0.18 0.25 0.32 0.5 0.34 0.45 0.07 0.07 0 0.1 0.13 0.13
Mitochondria 0.91 0.84 0.96 0.96 0.95 0.94 – 0.92 0.97 0.95 0.95 0.98 0.86 0.81 0.72 0.08 0.08 0.14 0.79 0.77 0.81 0.66 0.66 0.62
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0.07 0.13 – 0.09 0.14 0.1 0.12 0.1 0.05 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.08 – 0.08 0.07 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0.05 0 0 0 0 – 0 0 0 0 0 0.06 0 0 0.07 0.26 0.1 0 0 0.05 0.08 0.06 0.07
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0.15 0.14 0.05 0 0.08 0 – 0 0 0 0 0 0.1 0.08 0.09 0.18 0.15 0.12 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 3 1 0 0 0 – 1 0 0 0 0 1 5 3 4 1 2 11 19 4 6 12 21
Bud 5 2 26 16 9 13 – 21 24 27 17 15 1 3 0 3 6 5 1 0 0 1 1 2
Bud Neck 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 1
Bud Site 1 1 12 2 6 3 – 8 6 6 6 8 0 0 0 1 0 0 – – – – – –
Cell Periphery 13 17 12 8 3 7 – 3 6 8 7 19 14 17 20 21 14 22 0 0 0 0 0 1
Cytoplasm 4 4 15 12 16 11 – 12 10 17 6 6 8 20 16 13 16 14 0 0 0 0 0 0
Endoplasmic Reticulum 5 1 5 1 6 7 – 5 4 12 11 6 1 10 2 6 4 7 1 1 6 0 0 2
Endosome 10 24 3 1 1 4 – 5 0 1 0 1 14 19 19 8 9 4 22 20 26 12 12 18
Golgi 36 54 0 0 0 0 – 2 1 1 1 1 55 123 139 90 57 70 45 38 15 23 47 63
Mitochondria 567 430 542 428 315 579 – 850 810 884 541 622 265 395 318 14 14 22 513 428 461 159 237 294
Nucleus 5 5 3 2 7 2 – 18 3 8 5 2 1 0 1 1 1 1 1 0 0 0 1 0
Nuclear Periphery 26 14 15 13 22 80 – 82 116 89 69 63 14 18 10 3 3 4 4 2 5 1 3 4
Nucleolus 13 14 11 15 5 47 – 71 56 55 31 15 4 9 2 4 3 6 0 0 0 0 2 2
Peroxisomes 2 23 4 3 0 0 – 7 2 7 2 4 18 11 16 12 44 16 24 17 26 19 22 35
SpindlePole 3 2 13 3 2 4 – 20 4 3 4 5 1 2 3 4 8 7 0 2 2 1 1 1
Vac/Vac Membrane 93 73 31 14 28 23 – 36 30 24 19 18 30 39 39 33 26 19 19 16 11 8 11 20
Unique Cell Count 623 509 565 445 333 614 925 835 932 569 637 308 490 439 179 170 156 653 554 571 242 358 474
Labelled Cell Count 785 668 693 518 420 780 1141 1072 1142 719 785 427 671 588 217 206 199 653 554 571 242 358 474


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.0 9.1 4.8 5.7 4.0 5.5 – 5.4 5.1 5.4 5.4 5.1 9.3 8.9 8.8 10.2 10.1 9.5 9.5 9.8 9.8
Std Deviation (1e-4) 1.3 2.3 1.0 1.2 1.0 1.2 – 1.3 1.4 1.4 1.3 1.2 1.6 1.5 1.6 2.4 7.1 2.3 2.0 2.0 1.8
Intensity Change (Log2) – – – 0.23 -0.28 0.19 – 0.15 0.08 0.17 0.15 0.07 0.95 0.88 0.87 1.08 1.06 0.99 0.97 1.02 1.02

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud -0.8 0 -2.4 – -2.5 -1.7 -1.7 -1.4 -2.1 -3.5 -4.0 -4.6 -1.8 -0.6 -0.8
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site -2.3 0 -2.5 – -2.0 -2.3 -2.5 -1.4 -1.2 0 -3.2 -3.1 0 0 0
Cell Periphery -0.4 0 -1.3 – -3.4 -2.3 -2.1 -1.2 0.9 2.0 1.3 2.2 5.4 3.8 6.2
Cytoplasm 0 1.7 -1.0 – -1.9 -2.0 -1.1 -2.0 -2.3 -0.1 1.3 0.9 2.8 3.8 3.6
Endoplasmic Reticulum 0 0 0.4 – 0 0 0.7 1.5 0.1 0 1.6 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 4.1 3.8 4.1 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 10.4 12.7 14.4 18.0 14.3 16.8
Mitochondria 0.2 0 -1.3 – -3.1 1.1 -1.0 -0.7 1.7 -5.3 -7.9 -10.5 -23.6 -23.4 -21.9
Nucleus 0 0 0 – 2.2 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.3 0 6.5 – 4.7 7.1 5.1 6.1 5.1 1.5 0.9 -0.4 0 0 0
Nucleolus 1.4 0 4.5 – 4.7 4.1 3.6 3.1 0.5 -0.7 -0.1 -2.1 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 4.6 2.1 3.3 0 11.6 0
SpindlePole -2.1 0 -2.4 – -0.2 -3.1 -3.6 -2.2 -2.2 0 -2.6 -2.0 0 0 0
Vacuole -1.8 1.7 -1.4 – -1.4 -1.7 -2.9 -1.8 -2.3 2.4 1.6 2.1 5.4 4.2 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.0416 6.6772 6.3974 6.4402 5.7326 6.3589 5.6215 5.2114 5.4216 5.1257 4.4373 5.2148 8.1962 7.4145 7.3024 7.9423 6.7454 7.4408
Actin 0.0207 0.0115 0.007 0.0065 0.0015 0.0024 0.0062 0.0044 0.0015 0.0001 0.0006 0.0007 0.0036 0.0045 0.0026 0.0004 0.001 0.0008
Bud 0.0007 0.0008 0.0004 0.0007 0.0002 0.0001 0.0001 0.0002 0.0005 0 0.0001 0 0.0001 0.0003 0.0001 0.0001 0 0
Bud Neck 0.0009 0.0003 0.0004 0.0001 0.0001 0.0002 0.0002 0.0001 0.0001 0 0.0001 0.0001 0 0.0001 0.0001 0 0 0
Bud Periphery 0.0008 0.0014 0.0009 0.0027 0.0005 0.0002 0.0004 0.0005 0.0009 0.0001 0.0002 0.0001 0.0003 0.0007 0.0005 0.0004 0.0001 0.0001
Bud Site 0.0039 0.0019 0.0038 0.0003 0.0002 0.0002 0.001 0.0007 0.0012 0 0.0001 0 0.0002 0.0012 0.0003 0.0001 0 0
Cell Periphery 0.0004 0.0005 0.0011 0.0002 0.0002 0.0001 0.0003 0.0001 0.0005 0.0001 0.0001 0 0.0001 0.0002 0.0001 0.0001 0 0.0001
Cytoplasm 0.0057 0.0002 0.0004 0.0001 0.0001 0.0003 0.0001 0.0001 0.003 0 0.0029 0 0.0001 0.0001 0 0 0 0
Cytoplasmic Foci 0.0129 0.0054 0.0029 0.0032 0.0016 0.0024 0.0041 0.0049 0.0015 0.0008 0.0075 0.0005 0.0018 0.0048 0.0028 0.0007 0.0004 0.0006
Eisosomes 0.0003 0.0004 0.0006 0.0001 0.0003 0.0001 0.0003 0.0001 0.0003 0.0001 0.0001 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0016 0.0009 0.0004 0.0001 0.0002 0.0003 0.0003 0.0001 0.0013 0 0.0007 0.0001 0.0002 0.0002 0.0001 0.0001 0 0.0001
Endosome 0.0261 0.0277 0.0138 0.0159 0.0166 0.0155 0.0123 0.015 0.0062 0.0019 0.0226 0.0042 0.0134 0.0211 0.0103 0.0055 0.0007 0.0034
Golgi 0.0179 0.058 0.0211 0.0433 0.0344 0.0172 0.0209 0.0287 0.0098 0.0052 0.0339 0.0141 0.0208 0.0335 0.0221 0.0131 0.0027 0.0144
Lipid Particles 0.0197 0.0171 0.0147 0.003 0.0056 0.0033 0.0103 0.0063 0.0008 0.0004 0.0211 0.0045 0.0244 0.0099 0.0048 0.0009 0.0005 0.0066
Mitochondria 0.8281 0.8409 0.9039 0.9006 0.9213 0.9501 0.9228 0.9251 0.9602 0.9844 0.8651 0.97 0.9186 0.8966 0.9397 0.9664 0.9877 0.9651
None 0.0012 0.0001 0.0001 0.0001 0 0.0002 0.0003 0 0.0004 0 0.0007 0 0.0001 0.0001 0 0 0 0
Nuclear Periphery 0.0073 0.0049 0.0003 0.0001 0.0001 0.0006 0.0005 0.0001 0.0007 0 0.0175 0.0001 0.0022 0.0001 0.0001 0.0001 0 0.0001
Nucleolus 0.0014 0.0003 0.0015 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0 0.0004 0 0.0003 0.0002 0.0001 0 0 0.0001
Nucleus 0.0046 0.0002 0.0003 0.0001 0.0001 0.0002 0.0002 0.0001 0.0002 0 0.0083 0 0.0002 0.0001 0.0001 0 0 0
Peroxisomes 0.0161 0.0105 0.0094 0.0033 0.0025 0.0024 0.0108 0.0106 0.0043 0.006 0.0127 0.0033 0.0071 0.0136 0.0063 0.0035 0.0057 0.0058
Punctate Nuclear 0.0059 0 0.0001 0 0 0.0007 0.0015 0 0.0001 0 0.0022 0 0.0001 0 0 0 0 0
Vacuole 0.0107 0.0058 0.0064 0.0075 0.0031 0.001 0.0018 0.001 0.0017 0.0002 0.0013 0.0003 0.0015 0.0066 0.0029 0.001 0.0001 0.0005
Vacuole Periphery 0.0132 0.0112 0.0106 0.012 0.0115 0.0024 0.0053 0.0018 0.0046 0.0006 0.0019 0.0016 0.0047 0.0058 0.0069 0.0074 0.0007 0.0022

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.0082 11.1834 14.9374 27.424 24.3301 22.506 27.1381 32.8168 32.2684 31.127
Translational Efficiency 4.0694 3.5419 2.7414 1.6967 1.837 2.3793 1.8189 1.8428 2.049 1.7897

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2215 1229 143 1220 1638 1553 1646 1422 3853 2782 1789 2642

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 821.34 881.60 1223.46 1160.08 703.04 910.80 1061.63 1086.55 771.05 897.90 1074.57 1120.50
Standard Deviation 124.19 165.84 227.35 187.62 120.50 159.05 154.81 185.73 135.87 162.73 167.65 190.17
Intensity Change Log 2 — 0.102145 0.574915 0.498173 — 0.373528 0.594602 0.628076 — 0.233670 0.584028 0.559540

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001027 0.002764 0.005575 0.007344 0.001256 0.003976 0.002696 0.003581 0.001124 0.003441 0.002926 0.005319
Bud Neck 0.000630 0.001442 0.012206 0.001993 0.000616 0.001400 0.005682 0.001725 0.000624 0.001418 0.006203 0.001848
Bud Site 0.001345 0.003778 0.011813 0.008392 0.002106 0.003983 0.011132 0.009846 0.001668 0.003892 0.011186 0.009175
Cell Periphery 0.000385 0.000317 0.000299 0.000429 0.000495 0.000366 0.000438 0.000505 0.000431 0.000345 0.000427 0.000470
Cytoplasm 0.000321 0.000639 0.000912 0.001132 0.000270 0.000901 0.001671 0.001010 0.000300 0.000785 0.001610 0.001066
Cytoplasmic Foci 0.011129 0.025038 0.063256 0.013721 0.005392 0.014636 0.018395 0.013973 0.008690 0.019231 0.021981 0.013857
Eisosomes 0.000043 0.000083 0.000198 0.000116 0.000036 0.000074 0.000081 0.000093 0.000040 0.000078 0.000090 0.000104
Endoplasmic Reticulum 0.000251 0.000276 0.000745 0.001014 0.000318 0.000198 0.000336 0.000587 0.000279 0.000233 0.000368 0.000784
Endosome 0.029363 0.036911 0.038397 0.017866 0.009932 0.024637 0.032947 0.019387 0.021102 0.030060 0.033383 0.018684
Golgi 0.022783 0.044173 0.056250 0.068794 0.010719 0.025485 0.022273 0.048295 0.017654 0.033741 0.024989 0.057761
Lipid Particles 0.004528 0.007235 0.010136 0.002164 0.003192 0.003815 0.005304 0.003037 0.003960 0.005326 0.005690 0.002634
Mitochondria 0.896915 0.834966 0.680165 0.818642 0.943357 0.891518 0.834729 0.856395 0.916659 0.866535 0.822375 0.838962
Mitotic Spindle 0.001620 0.004939 0.020956 0.009093 0.001293 0.001946 0.018383 0.005385 0.001481 0.003268 0.018589 0.007097
None 0.000218 0.000274 0.001048 0.000613 0.000452 0.000284 0.000396 0.000426 0.000318 0.000280 0.000448 0.000513
Nuclear Periphery 0.000323 0.000094 0.004433 0.000972 0.000049 0.000065 0.000663 0.000423 0.000206 0.000078 0.000964 0.000676
Nuclear Periphery Foci 0.000246 0.000186 0.005314 0.000938 0.000154 0.000101 0.000684 0.000320 0.000207 0.000138 0.001054 0.000605
Nucleolus 0.000186 0.000150 0.001573 0.000303 0.000644 0.000169 0.000683 0.000212 0.000381 0.000161 0.000754 0.000254
Nucleus 0.000276 0.000144 0.000590 0.000139 0.001575 0.000308 0.000443 0.000079 0.000828 0.000236 0.000455 0.000107
Peroxisomes 0.013169 0.028960 0.045804 0.009896 0.013876 0.019293 0.021706 0.011619 0.013470 0.023564 0.023632 0.010823
Vacuole 0.005397 0.003900 0.021581 0.015814 0.001277 0.003500 0.012856 0.009599 0.003645 0.003677 0.013553 0.012469
Vacuole Periphery 0.009847 0.003731 0.018750 0.020625 0.002991 0.003343 0.008505 0.013504 0.006932 0.003514 0.009324 0.016792

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.94 -3.70 -5.13 -3.66 -1.05 -3.08 -2.60 -3.57 0.38 -1.09 -4.35 -3.55 -6.26 -2.31 -2.96
Bud Neck -2.34 -4.78 -4.64 -1.32 4.19 -2.08 -6.12 -2.88 -0.66 4.44 -3.07 -7.14 -4.99 -1.31 5.37
Bud Site -2.93 -2.60 -5.09 -2.97 0.80 -1.76 -5.69 -4.13 -3.04 0.57 -3.35 -6.76 -6.36 -4.18 1.14
Cell Periphery 0.59 0.74 -0.35 -1.11 -1.28 0.96 0.40 -0.08 -1.34 -0.60 0.99 0.03 -0.41 -1.72 -0.46
Cytoplasm -2.12 -3.46 -3.95 -2.15 -0.97 -1.93 -3.80 -3.16 -0.29 1.64 -2.49 -3.88 -4.86 -1.20 1.58
Cytoplasmic Foci -7.01 -5.73 -1.81 5.33 5.43 -6.33 -7.99 -5.95 0.36 2.26 -8.64 -7.92 -4.96 3.87 4.52
Eisosomes -6.27 -6.01 -6.14 -2.66 2.92 -6.11 -4.94 -8.77 -2.40 -1.14 -8.36 -5.91 -9.67 -3.58 -1.29
Endoplasmic Reticulum -0.36 -2.79 -2.76 -2.70 -0.87 1.30 -0.24 -1.64 -2.67 -1.70 0.83 -1.55 -3.28 -3.70 -2.74
Endosome -2.46 -1.40 4.88 6.68 3.22 -6.95 -9.34 -5.10 2.18 5.00 -4.72 -5.10 1.52 6.18 6.21
Golgi -6.53 -3.53 -9.55 -4.51 -1.20 -6.57 -5.46 -10.36 -5.80 -6.75 -8.24 -3.59 -13.44 -7.31 -9.81
Lipid Particles -1.74 -2.59 2.67 3.41 3.76 -0.63 -1.91 0.18 0.75 1.98 -1.52 -1.74 2.05 3.08 3.11
Mitochondria 6.91 7.21 8.34 1.49 -4.47 7.24 13.30 10.68 3.87 -2.23 8.79 12.35 12.49 3.89 -1.92
Mitotic Spindle -3.03 -4.61 -5.49 -2.54 2.66 -1.52 -8.72 -4.86 -3.95 6.22 -3.27 -9.34 -7.19 -4.31 5.82
None -1.24 -4.11 -11.28 -6.52 2.13 0.82 0.30 0.15 -1.89 -0.88 0.40 -1.48 -2.28 -4.90 -1.84
Nuclear Periphery 2.98 -3.02 -2.13 -2.96 2.48 -1.14 -5.64 -3.47 -3.33 1.58 2.91 -4.88 -3.04 -4.01 1.34
Nuclear Periphery Foci 0.98 -2.32 -2.54 -2.78 1.98 0.79 -4.74 -1.93 -3.92 3.48 1.55 -4.25 -2.97 -3.60 1.87
Nucleolus 0.31 -2.32 -0.62 -1.07 2.13 1.44 -0.09 1.30 -0.37 2.29 1.39 -1.56 0.77 -1.02 2.59
Nucleus 0.65 -1.25 0.67 0.04 2.87 1.54 1.38 1.86 1.35 3.39 1.58 0.97 2.00 1.27 3.44
Peroxisomes -4.90 -3.57 1.66 6.01 3.93 -2.10 -3.00 0.96 3.05 3.95 -5.05 -4.51 1.72 6.44 5.73
Vacuole 2.10 -4.06 -5.46 -6.28 1.30 -4.19 -10.71 -7.68 -5.21 2.18 -0.07 -9.23 -8.23 -8.13 0.74
Vacuole Periphery 7.77 -2.22 -6.05 -10.20 -0.44 -0.46 -5.35 -6.94 -7.11 -3.15 6.05 -2.52 -8.44 -12.21 -5.62
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Img2

Img2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Img2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available