Standard name
Human Ortholog
Description Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL2 has a paralog, SOL1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.97 0.99 0.96 0.99 0.99 0.94 0.88 0.81 0.76 0.81 0.66 0.8 0.99 0.99 1.0 0.98 0.99 0.97 0.94 0.98 0.95 0.96 0.91 0.91
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.05 0 0.05 0.16 0.19 0.33 0.23 0.39 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.06 0 0.08 0.08 0.07 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud 3 1 2 0 0 0 2 2 2 4 6 0 0 0 0 0 0 0 2 1 0 0 6 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 3 6 2 2 1 5 4 6 1 0 2 0 7 4 0 0 0 0 0 0
Cytoplasm 327 245 80 79 295 253 345 224 127 180 132 172 246 365 369 41 136 111 322 238 113 109 270 270
Endoplasmic Reticulum 1 0 0 0 0 1 4 4 2 1 3 2 1 3 1 1 9 4 0 0 0 0 2 2
Endosome 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 2 0 0 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 1 1
Mitochondria 12 1 0 4 2 14 64 51 55 51 77 39 0 0 0 0 0 0 3 0 1 1 2 2
Nucleus 1 2 1 1 1 4 5 0 3 7 2 3 2 0 0 0 3 3 0 0 0 0 0 0
Nuclear Periphery 0 0 1 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 1 0 0 0 2 2
Vac/Vac Membrane 2 1 0 0 1 5 15 17 7 17 16 16 0 0 1 1 0 2 0 0 2 0 1 1
Unique Cell Count 337 247 83 80 297 270 393 275 168 223 200 215 248 368 370 42 137 114 342 244 119 114 296 296
Labelled Cell Count 346 250 85 84 302 283 437 302 200 266 242 238 250 369 374 43 155 124 342 244 119 114 296 296


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 6.7 5.9 5.2 6.3 5.9 5.8 6.4 5.7 5.9 5.6 6.4 6.1 6.8 6.8 16.6 16.6 16.5 6.0 7.1 7.1
Std Deviation (1e-4) 1.1 1.4 1.2 0.9 1.7 1.4 1.2 1.3 1.2 1.2 1.2 1.2 1.1 1.2 1.2 4.9 3.8 4.2 1.2 1.6 1.6
Intensity Change (Log2) – – – -0.17 0.09 0.01 -0.03 0.11 -0.05 0.01 -0.07 0.11 0.06 0.2 0.2 1.5 1.49 1.48 0.03 0.27 0.27

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 2.1 -0.9 -2.3 -3.3 -4.1 -3.4 -5.4 -3.5 1.8 2.0 2.9 0.4 1.6 0.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 4.0 4.2 5.9 4.8 6.6 4.2 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.8938 0.8781 0.4985 0.5834 -0.244 0.6105 1.3969 1.5612 1.3999 1.4233 1.3327 1.2534 2.3199 2.1021 2.3115 2.2532 2.2712 1.7509
Actin 0.0336 0.0025 0.0047 0.0152 0.0045 0.0091 0.0461 0.0043 0.0155 0.0602 0.0258 0.0096 0.0348 0.0015 0.0212 0.0459 0.0503 0.0083
Bud 0.002 0.0095 0.0086 0.0004 0.0031 0.0015 0.0005 0.0038 0.0008 0.002 0.0024 0.0002 0.0008 0.0005 0.0247 0.0165 0.01 0.0006
Bud Neck 0.0057 0.0004 0.0006 0.0005 0.001 0.0011 0.0015 0.0005 0.0044 0.0015 0.0007 0.0005 0.0005 0.0002 0.0008 0.0009 0.0007 0.0008
Bud Periphery 0.0036 0.0025 0.0038 0.0005 0.0043 0.0017 0.0007 0.0029 0.0014 0.0067 0.0028 0.0002 0.0007 0.0002 0.0086 0.0129 0.0205 0.0002
Bud Site 0.0114 0.0124 0.0068 0.0003 0.0012 0.0007 0.0028 0.0138 0.0044 0.0037 0.0037 0.0002 0.0028 0.0016 0.0187 0.0106 0.0122 0.0001
Cell Periphery 0.0005 0.0002 0.0002 0.0001 0.0001 0.0001 0.0003 0.0002 0.0004 0.0006 0.0002 0 0.0003 0.0002 0.0007 0.0005 0.0008 0.0001
Cytoplasm 0.3542 0.5605 0.401 0.4049 0.3911 0.5466 0.3839 0.5489 0.4637 0.4433 0.4614 0.5587 0.7433 0.8834 0.7674 0.7161 0.6164 0.8183
Cytoplasmic Foci 0.0348 0.0179 0.0208 0.013 0.0435 0.0124 0.0322 0.0093 0.0126 0.0152 0.0151 0.0139 0.0274 0.0044 0.0114 0.0382 0.0105 0.0227
Eisosomes 0.0003 0.0001 0.0001 0.0001 0.0001 0 0.0006 0.0001 0.0002 0.0006 0.0002 0 0.0003 0 0.0002 0.0003 0.0003 0
Endoplasmic Reticulum 0.0041 0.0015 0.0023 0.0038 0.0045 0.0018 0.0077 0.0016 0.0028 0.0066 0.0041 0.0018 0.0063 0.0033 0.0079 0.0044 0.0092 0.003
Endosome 0.034 0.0027 0.0135 0.0282 0.0271 0.0143 0.0305 0.0022 0.007 0.0402 0.0288 0.0078 0.0092 0.0019 0.0088 0.0128 0.024 0.0077
Golgi 0.0093 0.0009 0.0069 0.0088 0.0053 0.0038 0.0121 0.0005 0.0039 0.0119 0.0076 0.0023 0.0034 0.0002 0.0023 0.0058 0.005 0.0027
Lipid Particles 0.0249 0.0009 0.0023 0.0044 0.0027 0.0035 0.0328 0.0002 0.0017 0.0122 0.0075 0.0016 0.0047 0.0004 0.0019 0.0025 0.0045 0.0014
Mitochondria 0.0095 0.0037 0.006 0.0028 0.0585 0.0026 0.0076 0.0007 0.0024 0.0312 0.0067 0.0011 0.0019 0.0002 0.0049 0.006 0.0057 0.0008
None 0.4005 0.3693 0.5006 0.4763 0.4113 0.3831 0.3779 0.3959 0.4609 0.2498 0.3964 0.392 0.1324 0.0964 0.1013 0.0809 0.1452 0.1219
Nuclear Periphery 0.0099 0.0011 0.0022 0.0048 0.0053 0.0019 0.0046 0.0008 0.0016 0.0368 0.0139 0.0013 0.0154 0.0011 0.0035 0.0061 0.0359 0.0025
Nucleolus 0.0039 0.0006 0.0007 0.0002 0.0007 0.0007 0.0008 0.0004 0.0006 0.0012 0.0009 0.0001 0.0005 0.0001 0.0014 0.0027 0.0026 0.0002
Nucleus 0.0065 0.0035 0.005 0.0032 0.0058 0.0045 0.0042 0.006 0.0041 0.0175 0.0053 0.0027 0.0056 0.0024 0.0074 0.0151 0.0126 0.0035
Peroxisomes 0.0279 0.0052 0.0049 0.0276 0.0134 0.0047 0.0467 0.0052 0.0069 0.041 0.0041 0.0032 0.0032 0.0001 0.001 0.0036 0.0097 0.0005
Punctate Nuclear 0.0171 0.0032 0.0067 0.0017 0.0116 0.004 0.0041 0.0018 0.0031 0.0096 0.0077 0.002 0.0043 0.0009 0.0034 0.0148 0.0014 0.0037
Vacuole 0.0047 0.0012 0.0019 0.002 0.0033 0.0015 0.002 0.0009 0.0013 0.0049 0.0023 0.0005 0.0013 0.0009 0.002 0.0023 0.0161 0.0007
Vacuole Periphery 0.0015 0.0002 0.0005 0.0012 0.0015 0.0004 0.0008 0.0001 0.0002 0.0033 0.0023 0.0002 0.0008 0.0001 0.0005 0.001 0.0062 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 33.172 19.7691 27.0229 32.3117 39.2362 39.5517 28.9308 35.5024 43.9208 30.1976
Translational Efficiency 1.4351 1.7704 1.7267 2.0559 1.3073 1.2745 1.3637 1.3866 1.4648 1.5398

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
973 253 1279 1639 60 1475 413 1484 1033 1728 1692 3123

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 689.66 883.02 958.63 1144.71 296.03 784.34 1124.26 1316.79 666.80 798.79 999.06 1226.48
Standard Deviation 89.62 131.28 157.05 221.27 7.26 124.06 167.96 239.91 126.67 129.91 174.91 245.83
Intensity Change Log 2 — 0.356561 0.475089 0.731025 — 1.405736 1.925160 2.153210 — 0.758360 1.079381 1.320332

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000137 0.000344 0.000249 0.000425 0.000037 0.000321 0.000403 0.000288 0.000131 0.000324 0.000287 0.000360
Bud Neck 0.009443 0.011550 0.001381 0.003882 0.000023 0.016034 0.002489 0.003134 0.008896 0.015378 0.001651 0.003527
Bud Site 0.003623 0.014653 0.003552 0.025001 0.000030 0.015211 0.015956 0.025047 0.003414 0.015129 0.006580 0.025023
Cell Periphery 0.000102 0.000096 0.000099 0.000078 0.000092 0.000110 0.000167 0.000116 0.000101 0.000108 0.000115 0.000096
Cytoplasm 0.554050 0.567607 0.636345 0.666583 0.000047 0.570905 0.560601 0.731971 0.521872 0.570422 0.617857 0.697654
Cytoplasmic Foci 0.222834 0.174983 0.010712 0.009809 0.000025 0.199470 0.015704 0.014549 0.209892 0.195885 0.011931 0.012061
Eisosomes 0.000108 0.000060 0.000016 0.000012 0.000097 0.000096 0.000054 0.000011 0.000107 0.000091 0.000026 0.000011
Endoplasmic Reticulum 0.000753 0.001156 0.002049 0.000850 0.000001 0.000500 0.002914 0.000367 0.000709 0.000596 0.002260 0.000621
Endosome 0.015473 0.015124 0.001271 0.005927 0.000002 0.016491 0.004766 0.005908 0.014574 0.016291 0.002124 0.005918
Golgi 0.001891 0.000740 0.000125 0.003080 0.000006 0.006181 0.000142 0.003936 0.001782 0.005385 0.000129 0.003487
Lipid Particles 0.006323 0.001772 0.000677 0.000444 0.000034 0.002673 0.002170 0.000495 0.005958 0.002541 0.001041 0.000468
Mitochondria 0.003312 0.000757 0.000233 0.001644 0.000012 0.005783 0.000219 0.000465 0.003120 0.005047 0.000229 0.001084
Mitotic Spindle 0.000763 0.008522 0.002201 0.043737 0.000297 0.005274 0.002049 0.043272 0.000736 0.005750 0.002164 0.043516
None 0.004040 0.002376 0.005152 0.015427 0.999062 0.002717 0.007760 0.006908 0.061835 0.002667 0.005789 0.011379
Nuclear Periphery 0.000390 0.001233 0.000669 0.000367 0.000000 0.000188 0.001101 0.000453 0.000368 0.000341 0.000774 0.000408
Nuclear Periphery Foci 0.000622 0.001278 0.002271 0.001741 0.000058 0.000596 0.007318 0.001742 0.000590 0.000696 0.003503 0.001742
Nucleolus 0.001032 0.000447 0.000156 0.000462 0.000048 0.000724 0.000320 0.000302 0.000975 0.000683 0.000196 0.000386
Nucleus 0.094293 0.072333 0.287210 0.146558 0.000014 0.060406 0.193511 0.090736 0.088817 0.062152 0.264339 0.120033
Peroxisomes 0.003920 0.008709 0.000114 0.000770 0.000109 0.008843 0.000289 0.000558 0.003699 0.008823 0.000157 0.000669
Vacuole 0.076031 0.115618 0.045349 0.071074 0.000003 0.085603 0.181633 0.068711 0.071616 0.089997 0.078615 0.069951
Vacuole Periphery 0.000858 0.000641 0.000169 0.002129 0.000000 0.001874 0.000434 0.001031 0.000808 0.001693 0.000234 0.001607

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.80 -5.61 -4.52 0.07 -0.04 -11.41 -7.98 -12.41 3.68 4.36 -5.44 -6.90 -4.54 1.50 3.08
Bud Neck -0.50 6.47 5.67 3.89 -1.81 -12.68 -10.22 -9.69 10.97 2.11 -3.92 6.21 5.95 11.34 -0.87
Bud Site -3.75 -0.50 -5.04 1.31 -4.17 -14.70 -4.58 -9.16 3.97 0.28 -11.42 -2.50 -7.31 4.14 -3.75
Cell Periphery 1.00 -1.75 2.71 0.76 3.90 -1.04 -3.58 1.13 4.27 7.20 -0.72 -3.59 3.96 4.10 7.18
Cytoplasm -0.30 -2.51 -3.49 -1.62 -0.99 -74.96 -34.42 -105.90 -8.39 -14.28 -3.99 -2.44 -9.61 -6.26 -9.17
Cytoplasmic Foci 4.26 31.92 32.51 14.22 3.56 -37.88 -14.63 -21.47 35.04 1.34 2.18 30.70 31.05 38.23 2.38
Eisosomes 7.03 16.22 17.73 8.62 4.96 0.14 1.99 4.13 9.61 11.96 2.07 14.90 18.64 10.18 12.33
Endoplasmic Reticulum -0.95 -8.35 0.44 1.15 10.70 -12.70 -14.30 -13.42 6.07 13.09 0.66 -10.42 1.72 1.79 15.71
Endosome 0.58 11.50 10.92 5.23 -0.18 -15.69 -11.14 -3.99 13.77 5.24 -0.79 10.89 11.19 14.71 2.19
Golgi 4.33 6.86 3.53 0.16 -2.02 -7.20 -15.79 -1.60 5.98 -1.18 -4.57 6.81 3.64 6.20 -2.19
Lipid Particles 6.20 8.09 8.25 3.05 1.27 -10.90 -11.99 -19.30 7.14 6.48 5.17 7.55 8.08 7.87 4.54
Mitochondria 2.85 3.36 3.07 0.95 -1.40 -4.45 -10.95 -8.76 4.31 2.69 -1.27 3.34 3.24 4.22 -0.91
Mitotic Spindle -1.57 -3.86 -7.59 -2.11 -6.43 -3.93 -3.85 -7.52 -4.85 -5.04 -3.72 -4.84 -10.41 -6.14 -8.50
None 1.51 -0.79 -4.42 -5.76 -5.43 2055.14 1434.08 2725.82 -5.15 1.12 8.12 7.80 7.51 -8.02 -4.52
Nuclear Periphery -0.86 -6.51 -3.05 0.56 7.76 -13.69 -20.40 -12.17 -7.29 12.10 0.24 -9.26 -2.88 -2.10 12.89
Nuclear Periphery Foci -2.36 -12.07 -9.40 -1.27 5.91 -8.01 -9.97 -15.65 -9.59 7.27 -1.49 -14.63 -12.79 -10.32 9.23
Nucleolus 2.99 4.46 3.94 2.88 -1.64 -8.25 -5.78 -2.96 6.30 1.97 1.60 4.29 4.13 6.28 -0.66
Nucleus 2.45 -29.04 -13.71 -11.83 17.81 -25.14 -23.14 -34.09 -11.95 11.36 6.00 -30.61 -11.74 -21.95 24.00
Peroxisomes -1.90 7.66 7.39 3.78 -1.10 -9.86 -3.39 -1.56 9.78 0.99 -5.26 7.61 7.48 10.45 -0.94
Vacuole -4.97 0.63 -15.62 -3.86 -16.36 -26.55 -21.13 -33.41 -14.17 5.96 -5.24 -8.38 -20.86 -16.33 -10.22
Vacuole Periphery 2.04 6.96 1.86 0.62 -1.47 -4.13 -4.05 -2.76 3.66 0.32 -2.14 6.79 3.45 3.34 -1.37
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL2 has a paralog, SOL1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (43%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Sol2

Sol2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sol2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available