Standard name
Human Ortholog
Description Protein containing a Kruppel-type zinc-finger domain; similar to Stp1p, Stp2p; predicted transcription factor; relative distribution to the nucleus increases upon DNA replication stress; STP4 has a paralog, STP3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.94 0.9 0.91 0.97 0.95 0.94 0.85 0.88 0.81 0.76 0.69 0.71 0.98 0.99 1.0 – 0.93 0.92 0.68 0.75 0.63 0.84 0.87 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.09 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0.14 0.09 0.15 0.14 0.1 0.17 0.36 0.21 0.31 0.45 0.55 0.46 0 0 0 – 0 0 0.16 0.09 0.23 0 0 0.06
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.06 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 1 4 0 1 0 1 4
Bud 0 1 0 0 1 0 2 0 3 1 3 4 0 1 0 – 0 1 0 0 0 1 3 7
Bud Neck 0 0 0 0 4 2 1 3 0 4 0 2 0 0 0 – 2 0 1 0 0 0 1 3
Bud Site 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 1 0 1 2 0 0 0 0 1 0 – 3 4 0 1 0 0 1 1
Cytoplasm 209 82 77 34 107 93 153 120 98 96 82 84 201 286 244 – 263 206 160 87 50 104 202 211
Endoplasmic Reticulum 0 1 0 0 0 1 0 0 0 0 1 0 1 1 0 – 26 20 1 0 1 0 1 3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 2 5 5 3 1 1 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 – 0 0 1 0 0 1 0 0
Mitochondria 30 8 13 5 11 17 66 29 38 57 66 54 3 2 1 – 8 6 38 10 18 5 9 14
Nucleus 0 0 1 0 0 1 2 2 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 1 1 2 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 3 0 1 0 0 0 0 0
SpindlePole 0 1 0 0 0 0 1 0 0 2 0 1 0 0 0 – 1 1 4 3 1 2 3 5
Vac/Vac Membrane 0 1 1 0 0 0 0 0 1 2 0 1 3 1 0 – 16 9 9 4 1 1 2 6
Unique Cell Count 222 91 85 35 113 99 181 136 121 126 119 118 206 289 244 282 223 234 116 80 124 233 267
Labelled Cell Count 239 94 92 39 124 115 227 155 145 163 154 146 209 292 245 324 254 234 116 80 124 233 267


Cytoplasm, Mitochondria, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.1 3.5 3.2 3.6 3.0 3.0 2.2 3.1 2.7 2.3 2.6 2.4 3.7 4.0 3.9 4.2 5.3 5.4 3.6 3.7 4.4
Std Deviation (1e-4) 0.4 0.9 1.2 1.8 1.3 1.9 1.0 1.8 1.6 1.0 1.4 1.3 1.3 1.4 1.2 1.5 2.4 2.3 1.3 1.7 1.5
Intensity Change (Log2) – – – 0.17 -0.06 -0.09 -0.51 -0.04 -0.22 -0.47 -0.27 -0.43 0.21 0.34 0.3 0.42 0.75 0.77 0.17 0.23 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.266 0.2067 0.3305 -0.1805 0.2541 0.2476 1.2908 1.2292 1.2539 1.0097 1.6597 1.063 2.056 1.0356 1.213 2.4598 1.3995 1.3655
Actin 0.0517 0.0003 0.0171 0 0.0171 0.0041 0.031 0.0003 0.0131 0.0048 0.0222 0.001 0.0442 0.0073 0.0117 0.0247 0.019 0.0074
Bud 0.0038 0.0088 0.0054 0.0001 0.0058 0.0002 0.001 0.005 0.0006 0.0006 0.0021 0.003 0.0007 0.0001 0.0003 0.0005 0.0014 0.0022
Bud Neck 0.0024 0.0008 0.0011 0.0003 0.0005 0.0025 0.0089 0.0015 0.0011 0.0005 0.0006 0.0009 0.0026 0.0001 0.0008 0.0002 0.0001 0.001
Bud Periphery 0.0049 0.0053 0.0109 0.0001 0.009 0.0009 0.0045 0.0025 0.0014 0.0006 0.0047 0.0007 0.0032 0.0001 0.0003 0.0016 0.0049 0.0124
Bud Site 0.0071 0.0224 0.0058 0.0001 0.001 0.0002 0.0083 0.0253 0.0129 0.0008 0.0068 0.0001 0.007 0.0022 0.0058 0.0009 0.0002 0.004
Cell Periphery 0.0006 0.0004 0.0003 0 0.0002 0.0001 0.001 0.0011 0.0014 0.0001 0.0006 0.0001 0.0043 0.0001 0.0002 0.0001 0.0002 0.0002
Cytoplasm 0.0763 0.0707 0.0648 0.0478 0.0472 0.131 0.0184 0.0243 0.0441 0.026 0.0122 0.0676 0.0499 0.0421 0.0557 0.0153 0.022 0.0688
Cytoplasmic Foci 0.0179 0.0043 0.0145 0.0012 0.0066 0.0102 0.028 0.0181 0.0142 0.0171 0.0313 0.0081 0.0263 0.0137 0.0082 0.0086 0.0027 0.004
Eisosomes 0.0007 0.0001 0.0005 0 0.0003 0.0002 0.0022 0.0001 0.0005 0.0001 0.0003 0.0001 0.0012 0.0003 0.002 0.0006 0.0002 0.0001
Endoplasmic Reticulum 0.0032 0.0014 0.0024 0.0004 0.0015 0.0017 0.0036 0.0004 0.0013 0.0011 0.0016 0.0007 0.0083 0.0006 0.0018 0.0013 0.0018 0.0009
Endosome 0.0122 0.0007 0.006 0.0003 0.0054 0.0031 0.0103 0.0009 0.0118 0.0303 0.0411 0.0015 0.0203 0.003 0.0023 0.0113 0.003 0.003
Golgi 0.0062 0.0001 0.003 0 0.0096 0.0005 0.0039 0.0002 0.0068 0.0189 0.0128 0.0002 0.0058 0.0031 0.001 0.0066 0.0121 0.0024
Lipid Particles 0.0093 0.0003 0.0046 0.0001 0.0101 0.0011 0.013 0.0012 0.0059 0.0111 0.0132 0.0005 0.0154 0.0049 0.0035 0.0035 0.0003 0.0052
Mitochondria 0.0062 0.0004 0.0169 0.0003 0.0309 0.0022 0.0109 0.0005 0.0072 0.0081 0.0224 0.0003 0.0032 0.0022 0.0007 0.0097 0.0015 0.0015
None 0.7061 0.8414 0.776 0.891 0.7857 0.7814 0.8126 0.8771 0.8558 0.8492 0.8011 0.8896 0.7534 0.9038 0.8861 0.8749 0.9259 0.8542
Nuclear Periphery 0.0073 0.0013 0.0098 0.0005 0.0018 0.0027 0.0096 0.0003 0.0019 0.0014 0.0012 0.0011 0.012 0.0007 0.002 0.0104 0.0019 0.0045
Nucleolus 0.0017 0.0013 0.0014 0.0007 0.0008 0.0013 0.0015 0.0078 0.0005 0.0005 0.0008 0.0006 0.0011 0.0003 0.0008 0.0007 0.0001 0.0005
Nucleus 0.0573 0.0344 0.0408 0.0561 0.0534 0.0443 0.0034 0.0217 0.0069 0.013 0.002 0.0122 0.0137 0.0083 0.0082 0.0021 0.0007 0.0152
Peroxisomes 0.0104 0.0002 0.005 0 0.0085 0.0005 0.0139 0.0013 0.0076 0.0102 0.0101 0.0055 0.0111 0.0024 0.0048 0.0033 0.0002 0.0015
Punctate Nuclear 0.012 0.0044 0.011 0.0007 0.0022 0.0097 0.0115 0.0038 0.0031 0.0036 0.0042 0.0058 0.0125 0.0043 0.003 0.0214 0.0009 0.0099
Vacuole 0.002 0.001 0.0017 0.0004 0.0014 0.0015 0.0017 0.0063 0.0012 0.0016 0.0064 0.0005 0.0024 0.0003 0.0005 0.0009 0.0005 0.0005
Vacuole Periphery 0.0008 0.0001 0.0011 0.0001 0.0009 0.0004 0.0008 0.0003 0.0005 0.0005 0.0025 0.0001 0.0015 0.0001 0.0001 0.0013 0.0003 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2.9963 0.6696 1.4907 3.1294 0.9712 2.9947 1.1849 3.8843 2.2661 1.9116
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
148 1399 1524 883 1482 1920 296 319 1630 3319 1820 1202

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 641.76 637.42 805.37 847.37 645.16 709.56 927.58 842.62 644.85 679.15 825.25 846.11
Standard Deviation 81.08 76.76 92.86 105.65 70.45 88.94 87.82 123.01 71.49 91.26 102.51 110.54
Intensity Change Log 2 — -0.009790 0.327618 0.400958 — 0.137268 0.523815 0.385225 — 0.065806 0.429308 0.393092

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000024 0.000861 0.000172 0.000610 0.000028 0.000193 0.000226 0.002342 0.000027 0.000474 0.000181 0.001069
Bud Neck 0.002597 0.027018 0.003458 0.011374 0.002526 0.039614 0.001027 0.011056 0.002532 0.034305 0.003063 0.011289
Bud Site 0.000273 0.009876 0.006438 0.036770 0.001195 0.013531 0.000966 0.068533 0.001111 0.011990 0.005548 0.045199
Cell Periphery 0.000212 0.000127 0.000117 0.000216 0.000090 0.000134 0.000162 0.000326 0.000101 0.000131 0.000124 0.000245
Cytoplasm 0.439845 0.429524 0.260718 0.302060 0.568002 0.389514 0.173093 0.376427 0.556366 0.406378 0.246467 0.321796
Cytoplasmic Foci 0.164191 0.207561 0.008755 0.009521 0.120556 0.216570 0.018967 0.014745 0.124518 0.212773 0.010416 0.010907
Eisosomes 0.000197 0.000117 0.000031 0.000050 0.000065 0.000121 0.000102 0.000058 0.000077 0.000119 0.000042 0.000052
Endoplasmic Reticulum 0.000428 0.000869 0.002105 0.005659 0.000266 0.000626 0.003858 0.004310 0.000281 0.000729 0.002390 0.005301
Endosome 0.002322 0.015879 0.001729 0.004934 0.002411 0.023351 0.003133 0.005025 0.002403 0.020201 0.001958 0.004959
Golgi 0.000446 0.002615 0.000084 0.003615 0.000248 0.004487 0.000067 0.004193 0.000266 0.003698 0.000081 0.003769
Lipid Particles 0.007272 0.010177 0.001289 0.001434 0.003825 0.008988 0.002974 0.001877 0.004138 0.009489 0.001563 0.001552
Mitochondria 0.006799 0.008537 0.000619 0.002000 0.000642 0.016479 0.000260 0.007399 0.001201 0.013131 0.000561 0.003433
Mitotic Spindle 0.000013 0.002611 0.001528 0.030092 0.000070 0.008647 0.000087 0.029702 0.000064 0.006103 0.001294 0.029988
None 0.003500 0.007874 0.007334 0.010068 0.007972 0.003400 0.007045 0.010512 0.007566 0.005286 0.007287 0.010186
Nuclear Periphery 0.000580 0.000743 0.001535 0.002442 0.000405 0.000688 0.001486 0.001481 0.000421 0.000711 0.001527 0.002187
Nuclear Periphery Foci 0.001152 0.000507 0.000655 0.002037 0.000246 0.000483 0.001257 0.001301 0.000328 0.000493 0.000753 0.001841
Nucleolus 0.002269 0.003515 0.000885 0.001311 0.000753 0.002690 0.001101 0.001410 0.000891 0.003038 0.000920 0.001337
Nucleus 0.343984 0.200322 0.681033 0.492633 0.273157 0.185482 0.709235 0.380502 0.279588 0.191737 0.685619 0.462874
Peroxisomes 0.005172 0.010580 0.000459 0.000828 0.001026 0.013582 0.000366 0.001292 0.001402 0.012317 0.000444 0.000951
Vacuole 0.018255 0.058907 0.020770 0.079831 0.016324 0.068688 0.074441 0.073743 0.016500 0.064565 0.029499 0.078216
Vacuole Periphery 0.000469 0.001781 0.000285 0.002515 0.000193 0.002733 0.000146 0.003765 0.000218 0.002332 0.000263 0.002847

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.27 -7.39 -4.38 0.11 -3.27 -5.63 -7.94 -2.76 -2.41 -2.06 -1.62 -11.54 -5.04 -1.40 -3.84
Bud Neck -11.87 -1.33 -5.48 7.43 -4.49 -16.46 3.14 -2.77 11.70 -3.37 -20.44 -1.49 -6.74 13.74 -5.07
Bud Site -8.86 -4.19 -6.10 -2.61 -3.82 -7.55 -0.48 -3.68 -1.88 -3.65 -9.75 -3.29 -6.71 -2.78 -5.04
Cell Periphery 4.70 4.95 1.69 -4.47 -4.84 -4.05 -6.57 -3.37 -1.99 -0.92 -3.96 -4.19 -6.96 -4.21 -4.40
Cytoplasm 0.57 10.11 11.34 19.87 2.90 20.03 32.45 18.64 7.32 -6.41 19.58 39.63 35.88 20.86 -0.10
Cytoplasmic Foci -3.25 12.68 12.77 36.19 1.15 -15.19 23.82 26.09 39.77 1.92 -16.78 30.81 31.24 55.20 1.44
Eisosomes 3.81 7.85 5.79 7.38 -10.99 -11.17 -6.46 -3.71 4.66 3.24 -9.48 6.92 -0.81 9.44 -8.66
Endoplasmic Reticulum -0.96 -5.78 -14.86 -18.22 -13.34 -5.48 -10.02 -10.66 -10.06 -1.31 -7.08 -18.44 -22.39 -21.09 -12.98
Endosome -12.21 1.01 -1.48 11.00 -2.51 -16.45 -2.63 -1.61 14.57 0.22 -20.24 0.91 -1.88 18.24 -2.59
Golgi -5.38 1.59 -0.65 1.44 -1.12 -8.17 5.52 -1.04 2.71 -1.21 -10.53 4.75 -1.23 3.02 -1.49
Lipid Particles -2.23 5.77 5.32 9.77 -2.58 -7.58 1.61 3.89 9.88 2.25 -9.35 7.91 7.14 14.51 -1.63
Mitochondria -0.28 1.03 0.90 8.24 -3.68 -11.22 6.18 -1.29 6.43 -1.50 -11.41 1.13 -0.80 11.36 -2.59
Mitotic Spindle -3.74 -4.24 -6.13 -5.11 -5.40 -6.71 -1.26 -4.31 -2.93 -4.28 -7.55 -4.13 -7.44 -5.02 -6.81
None -3.35 -2.76 -2.44 1.07 -0.02 4.35 1.93 0.27 -4.16 -1.74 2.24 1.29 0.69 -1.83 -0.68
Nuclear Periphery -1.21 -10.03 -18.62 -19.51 -13.17 -2.93 -10.66 -10.93 -9.31 -3.79 -4.18 -20.52 -24.99 -21.53 -13.37
Nuclear Periphery Foci 0.70 0.44 -0.81 -8.43 -6.91 -0.97 -6.53 -7.88 -5.43 -1.71 -0.83 -4.77 -9.93 -8.79 -7.48
Nucleolus -0.80 1.03 1.05 5.29 0.16 -8.25 -0.69 -0.09 6.12 0.34 -7.64 0.17 0.37 7.89 0.31
Nucleus 7.29 -17.15 -8.51 -27.81 13.13 11.97 -23.92 -7.68 -12.80 11.81 13.53 -48.50 -20.99 -31.69 17.63
Peroxisomes -1.38 1.52 1.52 14.69 0.07 -14.94 5.92 0.70 14.09 -1.25 -16.58 3.05 2.74 20.63 -0.64
Vacuole -8.79 -2.75 -17.66 -13.56 -17.59 -19.35 -9.78 -13.30 -9.53 -5.05 -23.62 -10.82 -23.74 -16.26 -18.65
Vacuole Periphery -5.09 0.90 -0.81 1.87 -1.33 -10.75 1.96 -1.06 1.54 -1.10 -13.94 -0.54 -1.78 3.06 -1.69
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein containing a Kruppel-type zinc-finger domain; similar to Stp1p, Stp2p; predicted transcription factor; relative distribution to the nucleus increases upon DNA replication stress; STP4 has a paralog, STP3, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (50%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Stp4

Stp4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Stp4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available