Standard name
Human Ortholog
Description 1-acyl-sn-glycerol-3-phosphate acyltransferase; catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.1 0.05 0.09 0.14 0.08 0.11 0.09 0.11 – 0.07 0.06 0.06 0.06 0.08 0.05 0 0.06 0.05 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0.11 0.06 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0.05 0 0 0.05 0 0 0 – 0.05 0 0 0.07 0 0.06 0.09 0.05 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0.43 0.92 0.9 0.8 0.84 0.82 0.63 0.41 – 0.16 0.16 0.16 0.8 0.84 0.79 0 0 0 0.61 0.93 0.94 0.84 0.84 0.82
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.24 0.08 0.22 0.34 0.12 0.1 0.18 0.19 – 0.18 0.08 0.12 0.32 0.25 0.25 0.85 0.9 0.84 0.2 0 0 0.05 0 0
Mitochondria 0.38 0 0 0.05 0 0.15 0.27 0.32 – 0.49 0.64 0.64 0 0 0 0.11 0.18 0.1 0 0 0 0 0 0
Nucleus 0.05 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.14 0 0 0 0 0 0 0.1 – 0.15 0.17 0.2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0 0 0 0.05 0 0.07 0.13 – 0.17 0.11 0.09 0 0 0 0 0 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 13 25 22 19 32 32 39 – 19 21 28 17 22 14 5 14 9 2 5 8 3 10 16
Bud 0 1 4 0 1 4 5 11 – 6 7 7 4 0 0 0 1 0 0 1 0 0 3 3
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1
Bud Site 0 0 0 0 0 0 0 0 – 0 0 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 11 5 4 8 6 3 0 – 1 1 2 9 33 19 3 3 5 0 0 2 1 2 3
Cytoplasm 1 12 8 6 11 11 9 11 – 13 9 5 21 13 18 17 12 14 1 3 0 3 5 3
Endoplasmic Reticulum 9 241 246 129 205 240 215 144 – 43 53 71 241 242 231 5 5 4 42 244 276 203 247 305
Endosome 0 0 0 1 0 0 2 1 – 3 0 5 0 0 0 0 0 0 2 0 0 2 4 3
Golgi 5 21 60 54 29 29 60 68 – 50 26 51 97 73 73 169 197 153 13 2 3 11 8 16
Mitochondria 8 0 8 8 7 44 92 113 – 134 207 281 0 0 0 22 39 18 0 0 1 3 2 8
Nucleus 1 0 0 0 0 1 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 1 3 4 4 11 3 – 9 11 11 0 1 1 0 0 0 2 0 0 2 0 0
Nucleolus 3 2 3 0 0 5 15 34 – 40 55 86 4 4 3 7 5 5 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 0 0 – 1 0 0 0 1 0 0 0 0 0 0 0 0 1 0
Vac/Vac Membrane 2 6 2 5 11 11 23 47 – 47 37 39 5 8 12 1 2 11 0 2 0 6 4 6
Unique Cell Count 21 263 274 161 243 291 341 352 274 325 437 302 289 294 198 220 183 70 264 295 243 293 374
Labelled Cell Count 31 307 362 232 295 387 467 472 366 427 588 398 397 371 229 278 219 70 264 295 243 293 374


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 27.8 35.4 23.8 21.8 20.8 18.1 17.8 18.4 – 16.4 17.0 17.4 28.9 27.3 27.6 39.2 41.2 42.2 29.1 30.2 30.2
Std Deviation (1e-4) 10.6 5.9 3.9 3.4 3.6 3.2 3.1 3.1 – 3.6 3.3 3.9 6.2 5.2 5.4 10.7 10.0 10.8 6.1 6.3 6.3
Intensity Change (Log2) – – – -0.13 -0.19 -0.39 -0.42 -0.37 – -0.54 -0.48 -0.45 0.28 0.2 0.21 0.72 0.79 0.83 0.29 0.34 0.34


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.5 -0.5 0.7 0.1 0.8 – -0.9 -1.2 -1.3 -1.6 -0.6 -2.1 -2.9 -1.1 -1.7
Bud 0 0 0 0 1.4 – 0.6 0.6 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 1.1 0.2 0 0 – 0 0 0 0.9 4.5 2.7 0 0 0
Cytoplasm 0.5 1.0 0.6 -0.2 0.1 – 1.1 -0.1 -1.7 2.2 1.0 1.8 2.7 1.4 2.3
Endoplasmic Reticulum -2.8 -1.8 -2.5 -7.6 -12.5 – -17.4 -17.9 -19.2 -3.3 -2.1 -3.6 -18.7 -19.3 -18.4
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 2.7 -3.0 -3.9 -1.3 -0.8 – -1.1 -4.8 -3.7 2.8 0.9 0.8 13.6 15.0 13.0
Mitochondria 1.1 0 5.0 8.0 9.2 – 12.3 15.4 16.2 0 0 0 3.6 5.6 3.1
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 2.5 0 – 2.6 2.6 0 0 0 0 0 0 0
Nucleolus 0 0 0 2.4 4.5 – 5.9 6.5 7.3 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 0 2.8 2.4 3.8 5.8 – 6.7 5.3 4.6 0 0 2.6 0 0 3.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 23.2031 27.4104 23.6389 23.4212 22.7053 24.4401 27.7275 29.8772 27.9439 26.4931 25.4833 28.0729 26.4722 27.4494 26.8512 26.2375 23.2648 26.1766
Actin 0.0024 0.0002 0.0008 0.0123 0.0141 0.0032 0.0069 0.0003 0.0006 0.0127 0.0058 0.0011 0.0011 0.0005 0.0012 0.0002 0.0009 0.0004
Bud 0.0001 0 0 0.0003 0.0001 0 0.0001 0 0 0 0.0001 0 0 0 0 0 0 0
Bud Neck 0.0003 0.0002 0.0007 0.0009 0.0001 0.0006 0.0003 0.0001 0.0001 0.0001 0.0002 0.0001 0.0002 0.0003 0.0002 0.0001 0.0001 0.0002
Bud Periphery 0.0002 0 0.0002 0.0009 0.0001 0.0001 0.0003 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0 0
Bud Site 0.0006 0 0 0.0006 0.0002 0.0001 0.0006 0 0 0.0003 0.0001 0 0.0001 0.0001 0 0 0.0001 0
Cell Periphery 0.0151 0.0228 0.017 0.011 0.0077 0.0066 0.0117 0.0116 0.0109 0.0077 0.0035 0.0045 0.0144 0.0206 0.0171 0.0122 0.0053 0.0055
Cytoplasm 0.0059 0.0078 0.0021 0.0018 0.0017 0.0019 0.0042 0.001 0.0016 0.0006 0.0019 0.0006 0.004 0.0144 0.0011 0.0008 0.0076 0.0011
Cytoplasmic Foci 0.0069 0.0014 0.0018 0.005 0.0033 0.0025 0.0052 0.0016 0.002 0.0061 0.0055 0.0007 0.0038 0.0022 0.0019 0.0011 0.0122 0.0011
Eisosomes 0.0007 0.0021 0.0004 0.0026 0.0012 0.0003 0.001 0.0005 0.0004 0.0001 0.0004 0.0001 0.0004 0.0003 0.0004 0.0037 0.0001 0.0002
Endoplasmic Reticulum 0.4791 0.5815 0.6855 0.6175 0.7123 0.6877 0.614 0.7388 0.8038 0.7129 0.7079 0.798 0.5535 0.6218 0.5858 0.7412 0.7293 0.7505
Endosome 0.0225 0.0037 0.0103 0.0215 0.0104 0.0075 0.0136 0.0051 0.007 0.0041 0.0095 0.0053 0.0142 0.006 0.0071 0.0051 0.0155 0.0059
Golgi 0.025 0.0095 0.0203 0.0392 0.0236 0.0206 0.0204 0.0163 0.0187 0.0143 0.0465 0.0153 0.0254 0.0069 0.0346 0.0279 0.0284 0.0281
Lipid Particles 0.3292 0.3283 0.2347 0.2408 0.1894 0.2255 0.2533 0.2148 0.1318 0.2028 0.1685 0.1489 0.3196 0.2984 0.3376 0.1901 0.1715 0.181
Mitochondria 0.0065 0.0001 0.0005 0.0174 0.0061 0.001 0.0041 0.0004 0.0086 0.0015 0.0014 0.0006 0.0014 0.0004 0.0003 0.0005 0.0002 0.0002
None 0.0008 0.0002 0.0001 0.0016 0.0008 0.0003 0.0038 0.0001 0.0001 0.0001 0.0029 0.0001 0.0003 0.0001 0.0001 0.0002 0.0082 0.0001
Nuclear Periphery 0.0792 0.0255 0.0147 0.0075 0.0213 0.0326 0.0395 0.004 0.0077 0.0134 0.0181 0.0189 0.0452 0.0166 0.0061 0.0117 0.0141 0.0205
Nucleolus 0.0014 0.0001 0.0001 0.0004 0.0001 0.0004 0.0008 0 0 0 0.0021 0 0.0002 0.0001 0 0 0.0001 0
Nucleus 0.0034 0.0022 0.0002 0.0008 0.0003 0.0006 0.0025 0 0.0001 0 0.0111 0.0002 0.0008 0.0002 0.0001 0.0001 0.0002 0.0001
Peroxisomes 0.0004 0 0 0.0004 0.0004 0.0001 0.0009 0 0.0001 0.0178 0.0002 0 0.0001 0 0 0 0.0002 0
Punctate Nuclear 0.0023 0.0002 0.0002 0.0006 0.0003 0.0021 0.0016 0 0.0001 0.0002 0.0095 0.0003 0.0004 0.0002 0.0001 0.0001 0.0015 0.0001
Vacuole 0.0129 0.0126 0.0085 0.0135 0.0037 0.0045 0.0105 0.0047 0.0045 0.004 0.0026 0.0033 0.0113 0.0099 0.0055 0.0038 0.0032 0.0034
Vacuole Periphery 0.0052 0.0016 0.002 0.0034 0.0027 0.002 0.0048 0.0007 0.0017 0.001 0.0022 0.0019 0.0034 0.0009 0.0008 0.0011 0.0013 0.0015

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 74.4072 69.2194 47.351 55.3265 72.9424 64.0878 70.5344 74.9148 72.0455 82.269
Translational Efficiency 1.2205 1.0525 1.2332 1.1156 0.9118 1.3561 1.0798 0.9977 0.9333 0.8784

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1768 1507 332 1857 1964 1305 2612 1313 3732 2812 2944 3170

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1853.25 2295.47 2708.85 3105.73 1870.32 1891.13 2725.55 2935.78 1862.23 2107.82 2723.67 3035.34
Standard Deviation 354.20 422.99 362.84 591.37 472.11 343.26 417.73 623.29 420.48 437.30 411.94 610.56
Intensity Change Log 2 — 0.308732 0.547623 0.744875 — 0.015963 0.543262 0.650459 — 0.169093 0.545434 0.698223

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000408 0.002499 0.000197 0.006499 0.003203 0.001954 0.003091 0.010025 0.001879 0.002246 0.002765 0.007960
Bud Neck 0.000225 0.001416 0.003647 0.005214 0.001143 0.000682 0.001610 0.004949 0.000708 0.001076 0.001840 0.005104
Bud Site 0.001422 0.002256 0.000610 0.005919 0.004322 0.001838 0.000899 0.006345 0.002948 0.002062 0.000866 0.006095
Cell Periphery 0.003142 0.002510 0.006590 0.004656 0.002112 0.002084 0.002512 0.007384 0.002600 0.002312 0.002972 0.005786
Cytoplasm 0.001448 0.000479 0.000120 0.000717 0.001777 0.001116 0.000263 0.000773 0.001621 0.000775 0.000247 0.000740
Cytoplasmic Foci 0.002661 0.001078 0.000075 0.004169 0.003843 0.001801 0.001343 0.003118 0.003283 0.001413 0.001200 0.003734
Eisosomes 0.000095 0.000364 0.000237 0.000863 0.000477 0.000166 0.000982 0.001457 0.000296 0.000272 0.000898 0.001109
Endoplasmic Reticulum 0.937597* 0.795092* 0.894678* 0.371870* 0.745693* 0.907372* 0.567231* 0.442436* 0.836606* 0.847199* 0.604158* 0.401098*
Endosome 0.014479 0.038288 0.012357 0.062534 0.037955 0.020688 0.047387 0.046710 0.026833 0.030120 0.043437 0.055980
Golgi 0.010319 0.033656 0.016101 0.081711 0.042978 0.016893 0.071997 0.090485 0.027506 0.025876 0.065694 0.085345
Lipid Particles 0.013539 0.110336* 0.028039 0.404525* 0.109554* 0.032315 0.283539* 0.338026* 0.064068 0.074128 0.254726* 0.376981*
Mitochondria 0.000584 0.000285 0.000155 0.001583 0.001040 0.000401 0.000307 0.001982 0.000824 0.000339 0.000289 0.001749
Mitotic Spindle 0.000092 0.000113 0.000050 0.002989 0.000368 0.001448 0.000060 0.001824 0.000237 0.000732 0.000058 0.002506
None 0.001155 0.001592 0.000066 0.000775 0.004980 0.000924 0.001789 0.000417 0.003168 0.001282 0.001594 0.000627
Nuclear Periphery 0.000694 0.001119 0.007031 0.002785 0.001906 0.000698 0.001618 0.002235 0.001332 0.000924 0.002229 0.002557
Nuclear Periphery Foci 0.004471 0.003382 0.008739 0.011849 0.021424 0.004006 0.003651 0.006604 0.013393 0.003672 0.004225 0.009677
Nucleolus 0.000008 0.000007 0.000011 0.000033 0.000214 0.000010 0.000009 0.000299 0.000116 0.000008 0.000010 0.000143
Nucleus 0.000078 0.000040 0.000050 0.000124 0.001009 0.000213 0.000032 0.000315 0.000568 0.000120 0.000034 0.000203
Peroxisomes 0.000301 0.000126 0.000003 0.000106 0.000192 0.000057 0.000205 0.000165 0.000243 0.000094 0.000182 0.000131
Vacuole 0.005006 0.004197 0.017577 0.024967 0.011609 0.003645 0.008779 0.027471 0.008481 0.003941 0.009771 0.026004
Vacuole Periphery 0.002275 0.001168 0.003668 0.006111 0.004201 0.001688 0.002695 0.006980 0.003289 0.001409 0.002805 0.006471

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.08 1.16 -5.86 -3.33 -6.03 1.26 0.13 -3.80 -4.37 -3.97 -0.62 -1.68 -6.22 -5.49 -5.18
Bud Neck -3.18 -2.55 -8.88 -5.73 -0.91 2.44 -1.98 -6.78 -7.57 -5.82 -1.69 -4.65 -10.87 -9.02 -7.13
Bud Site -1.13 1.24 -5.23 -3.91 -6.36 2.83 4.86 -2.12 -4.87 -6.86 1.43 4.76 -4.82 -6.04 -9.30
Cell Periphery 0.86 -2.45 -3.00 -3.60 1.33 0.13 -1.87 -8.97 -8.63 -8.33 0.72 -1.24 -8.71 -8.22 -8.12
Cytoplasm 2.40 3.39 1.52 -1.40 -3.36 1.03 5.26 2.46 0.74 -2.27 2.45 5.78 2.88 0.09 -3.63
Cytoplasmic Foci 2.34 4.42 -2.24 -6.27 -11.02 3.09 4.95 1.10 -2.11 -3.88 4.01 5.24 -1.00 -5.94 -8.19
Eisosomes -3.10 -2.89 -7.69 -3.83 -5.75 2.55 -2.28 -3.90 -5.86 -1.62 0.30 -3.40 -6.47 -7.13 -1.04
Endoplasmic Reticulum 18.11 4.03 66.30* 40.14* 38.27* -17.54* 17.43 24.90 42.25* 10.66 -1.61 29.21 57.29 58.16* 22.82
Endosome -13.92 1.16 -23.02 -9.79 -20.57 8.90 -4.55 -3.60 -11.76 0.25 -2.42 -10.81 -17.57 -15.15 -6.78
Golgi -11.84 -2.78 -24.26 -14.74 -19.75* 10.62 -9.57 -11.78 -20.12 -4.55 0.99 -16.49 -23.25 -24.53 -6.71
Lipid Particles -17.77* -2.90 -51.68* -32.01* -40.85* 13.81 -22.55 -23.21 -33.79* -5.14 -2.42 -30.71 -49.81 -46.38* -15.23
Mitochondria 1.94 2.85 -2.56 -3.52 -3.88 1.76 2.13 -1.52 -2.82 -3.04 2.41 2.73 -2.60 -4.44 -4.64
Mitotic Spindle -0.33 1.20 -3.52 -3.48 -3.56 -1.53 2.78 -1.92 -0.38 -2.33 -1.50 2.95 -3.93 -2.70 -4.26
None -0.89 4.01 0.96 1.66 -3.82 3.92 3.10 4.49 1.31 3.65 3.16 2.64 4.49 2.04 2.96
Nuclear Periphery -3.07 -5.48 -8.43 -6.25 3.62 3.19 0.69 -0.96 -7.07 -2.87 1.93 -3.66 -5.01 -9.13 -1.42
Nuclear Periphery Foci 1.10 -2.65 -6.10 -7.93 -1.58 6.67 7.23 5.76 -2.35 -3.88 6.75 6.54 2.39 -7.50 -7.50
Nucleolus 0.68 -0.67 -2.72 -2.84 -2.37 2.92 2.92 -0.37 -1.26 -1.26 2.94 2.90 -0.29 -1.43 -1.41
Nucleus 2.66 1.47 -2.22 -4.00 -3.23 1.46 1.89 1.27 -0.42 -1.66 1.58 1.96 1.25 -0.90 -2.47
Peroxisomes 1.46 2.61 1.69 0.47 -6.45 1.71 -0.14 0.24 -1.16 0.40 2.12 0.79 1.46 -0.83 0.93
Vacuole 1.12 -5.22 -11.84 -12.43 -2.37 5.85 2.00 -6.90 -11.58 -8.97 5.63 -1.36 -12.44 -17.01 -11.57
Vacuole Periphery 2.92 -1.57 -5.89 -8.84 -2.42 4.06 3.25 -4.09 -7.44 -7.35 5.27 1.42 -6.67 -11.27 -8.44
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description 1-acyl-sn-glycerol-3-phosphate acyltransferase; catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes
Localization
Cell Percentages ER (99%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Slc1

Slc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Slc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available