Standard name
Human Ortholog
Description Transport adaptor or symportin; facilitates synchronized nuclear coimport of the two 5S-rRNA binding proteins Rpl5p and Rpl11p; binds to nascent Rpl5p during translation; required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.16 0.07 0.16 0.09 0.09 0.11 0.1 0.12 0.1 0.08 0.09 0.07 – 0.39 0.29 0.07 0.11 0.09 0.08 0 0.07 0.18 0.06 0.07
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.06 0 0.16 0.06 0.34 0.12 – 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.39 0.47 0.49 0.86 0.88 0.79 0.79 0.76 0.79 0.82 0.72 0.74 – 0.38 0.55 0.68 0.7 0.7 0.7 0.76 0.63 0.55 0.54 0.45
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.06 0 0.07 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.59 0.58 0.56 0.07 0 0.05 0.08 0.06 0 0.06 0 0.12 – 0.29 0.16 0.26 0.21 0.2 0.12 0.12 0.21 0.13 0.15 0.25
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 0 1 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 1 0
Bud 1 0 0 0 0 0 1 1 2 1 0 0 – 0 0 0 0 0 12 4 7 0 4 1
Bud Neck 0 0 0 0 0 0 1 0 0 2 0 0 – 0 0 0 0 0 0 1 0 0 0 1
Bud Site 0 0 0 0 0 1 2 0 3 2 4 8 – 0 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 62 25 33 19 22 30 41 37 28 21 22 15 – 40 36 17 23 18 34 11 14 8 4 10
Endoplasmic Reticulum 0 3 0 0 0 0 0 1 0 0 0 0 – 1 0 5 6 2 0 1 1 0 1 4
Endosome 2 4 1 0 0 2 2 1 0 2 0 3 – 2 1 2 0 3 5 5 1 1 3 6
Golgi 0 1 0 0 0 1 0 0 0 0 0 0 – 0 1 2 6 0 1 2 0 0 0 1
Mitochondria 5 0 0 1 1 15 25 11 44 16 88 26 – 0 1 3 2 0 2 5 2 0 0 2
Nucleus 152 161 99 191 226 221 308 240 218 229 186 167 – 39 68 157 152 135 288 293 130 24 39 61
Nuclear Periphery 0 0 0 3 0 2 3 1 2 0 1 1 – 0 0 1 1 0 2 1 0 0 1 1
Nucleolus 1 0 0 2 2 4 6 9 17 5 18 8 – 2 1 5 2 7 4 5 0 0 1 4
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 2 3 5 1 4 3 5 – 0 2 0 0 0 5 5 0 0 1 3
Vac/Vac Membrane 230 196 113 16 8 13 30 20 11 17 10 26 – 30 20 60 46 39 48 44 43 5 11 34
Unique Cell Count 387 340 202 221 257 279 391 314 275 278 258 225 103 123 231 216 194 410 386 206 45 74 137
Labelled Cell Count 453 390 246 234 259 291 423 326 326 299 332 260 114 131 252 238 204 410 386 206 45 74 137


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.1 11.9 10.0 9.9 9.7 7.4 7.3 7.4 6.3 6.7 5.9 6.2 – 9.3 9.2 16.4 18.0 16.6 – 10.2 9.8
Std Deviation (1e-4) 1.9 2.3 1.5 2.1 2.2 1.7 1.9 1.6 1.5 1.5 1.6 1.3 – 2.1 2.6 4.5 4.7 4.6 – 2.0 2.2
Intensity Change (Log2) – – – -0.01 -0.04 -0.44 -0.45 -0.42 -0.65 -0.58 -0.77 -0.68 – -0.1 -0.12 0.72 0.85 0.74 – 0.03 -0.03

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Cytoplasm -2.4 -2.5 -1.8 -2.0 -1.5 -2.0 -3.0 -2.6 -3.2 – 4.4 2.8 -2.9 -1.7 -2.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Mitochondria 0 0 3.3 3.7 0 6.0 3.5 9.2 5.0 – 0 0 0 0 0
Nucleus 8.3 9.1 6.9 7.4 6.4 6.9 7.8 5.1 5.4 – -1.8 1.1 4.0 4.5 4.2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Nucleolus 0 0 0 0 0 3.6 0 3.8 0 – 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Vacuole -10.9 -12.8 -12.6 -13.0 -12.6 -12.8 -12.1 -12.5 -9.8 – -4.4 -7.1 -6.4 -7.3 -7.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.6011 8.3277 7.0024 7.5008 7.3912 7.1576 5.5471 7.8489 7.1574 6.6817 6.2097 6.7907 6.1508 8.429 7.3312 6.6019 6.2706 7.3894
Actin 0.0195 0.0008 0.0054 0.0005 0 0.0001 0.0271 0 0.006 0.0304 0.0031 0.0172 0.014 0 0.0019 0.0165 0.0202 0.002
Bud 0.0003 0.0009 0.0042 0.0001 0 0.0003 0.0006 0 0.0009 0.0006 0.0017 0.0004 0.0002 0 0.0002 0.0015 0.0013 0.0001
Bud Neck 0.0011 0.0004 0.0038 0.0003 0.0012 0.0021 0.0031 0.0001 0.0025 0.0048 0.001 0.0026 0.0012 0.0001 0.0002 0.0008 0.0025 0.0012
Bud Periphery 0.0009 0.0003 0.0044 0.0001 0.0001 0.0013 0.001 0 0.0018 0.0006 0.0039 0.0011 0.0002 0 0.0003 0.0011 0.003 0.0002
Bud Site 0.0009 0.002 0.0135 0.0001 0.0001 0.0003 0.0037 0 0.0061 0.0026 0.0019 0.0008 0.0086 0.0001 0.0017 0.0011 0.001 0.0001
Cell Periphery 0.0005 0.0001 0.0006 0 0 0.0005 0.0005 0 0.0007 0.0001 0.0003 0.0005 0.0001 0 0.0001 0.0002 0.0005 0
Cytoplasm 0.0048 0.0031 0.0009 0.0011 0.0006 0.0008 0.007 0.0065 0.0013 0.0053 0.0141 0.0012 0.0041 0.0017 0.0024 0.0632 0.0054 0.0006
Cytoplasmic Foci 0.0123 0.0002 0.0067 0.0003 0 0 0.011 0 0.0019 0.0094 0.0108 0.0058 0.0241 0 0.006 0.0073 0.0074 0
Eisosomes 0.0002 0 0.0001 0 0 0 0.0005 0 0.0002 0.0001 0 0.0001 0.0001 0 0 0.0001 0.0001 0
Endoplasmic Reticulum 0.004 0.0002 0.0009 0.0006 0.0001 0.0004 0.0036 0.0001 0.0008 0.0036 0.0055 0.0015 0.0009 0 0.0004 0.0008 0.0028 0.0004
Endosome 0.0126 0.0029 0.0072 0.0004 0.0001 0.0001 0.0171 0.0001 0.0051 0.0168 0.0332 0.0128 0.0094 0 0.0091 0.0179 0.0067 0.0005
Golgi 0.0014 0.0028 0.0021 0 0 0 0.007 0 0.0036 0.0069 0.0098 0.0052 0.0044 0 0.0077 0.0443 0.0067 0.0001
Lipid Particles 0.0077 0.0003 0.004 0 0 0 0.022 0 0.0027 0.0042 0.0267 0.006 0.0249 0 0.0044 0.0054 0.0081 0.0001
Mitochondria 0.0259 0.0007 0.0077 0.0007 0.0002 0.0005 0.0131 0.0001 0.006 0.0023 0.0116 0.0048 0.0019 0.0002 0.015 0.0153 0.0101 0.0043
None 0.0054 0.0001 0.0004 0.0001 0 0 0.0035 0 0.0003 0.0009 0.0021 0.0005 0.0014 0 0.001 0.001 0.0007 0.0001
Nuclear Periphery 0.0201 0.0042 0.0054 0.0267 0.0037 0.0012 0.0243 0.0028 0.0049 0.0054 0.0403 0.0041 0.0115 0.0024 0.0061 0.0046 0.021 0.0102
Nucleolus 0.0222 0.0058 0.0087 0.0084 0.0087 0.0236 0.0168 0.0044 0.0069 0.0119 0.0168 0.0193 0.0066 0.0068 0.0168 0.0053 0.0275 0.0287
Nucleus 0.8285 0.9707 0.9107 0.9294 0.9701 0.9642 0.8095 0.9845 0.942 0.8814 0.7292 0.9014 0.8482 0.9872 0.9085 0.7824 0.8383 0.9476
Peroxisomes 0.0096 0.0001 0.0069 0 0 0 0.0102 0 0.0014 0.0064 0.0066 0.0047 0.0265 0 0.006 0.0013 0.0239 0
Punctate Nuclear 0.0137 0.0034 0.0006 0.0301 0.0141 0.0016 0.0129 0.0012 0.0022 0.0053 0.0109 0.0057 0.011 0.0012 0.0052 0.0276 0.0062 0.003
Vacuole 0.0055 0.0008 0.0039 0.0004 0.0007 0.0024 0.0035 0.0002 0.0023 0.0006 0.0447 0.0024 0.0006 0.0002 0.0048 0.0012 0.0045 0.0004
Vacuole Periphery 0.0029 0.0004 0.0019 0.0005 0.0002 0.0004 0.002 0 0.0006 0.0004 0.0259 0.0019 0.0003 0.0002 0.002 0.0009 0.0022 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 54.7852 44.4743 37.7164 30.9419 36.4756 27.8214 34.7966 28.7244 17.6343 38.51
Translational Efficiency 0.9565 1.0852 1.0135 0.6931 0.7867 1.0771 0.9966 0.6538 0.8104 0.8182

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
147 1373 661 1538 1749 1266 1249 881 1896 2639 1910 2419

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 718.63 983.52 945.61 1278.86 969.19 1037.57 1161.88 1343.06 949.76 1009.45 1087.03 1302.24
Standard Deviation 103.03 238.34 195.94 253.21 145.25 185.45 198.47 252.74 157.40 216.30 222.78 254.92
Intensity Change Log 2 — 0.452705 0.395996 0.831537 — 0.098357 0.261610 0.470672 — 0.259973 0.320365 0.635463

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000550 0.000542 0.000839 0.000978 0.000380 0.000446 0.000648 0.000624 0.000393 0.000496 0.000714 0.000849
Bud Neck 0.024266 0.010916 0.008734 0.029741 0.007604 0.009687 0.015449 0.024272 0.008895 0.010326 0.013125 0.027749
Bud Site 0.011442 0.003318 0.002574 0.004869 0.001478 0.002939 0.002680 0.006825 0.002251 0.003136 0.002643 0.005581
Cell Periphery 0.000290 0.000548 0.000191 0.000356 0.000290 0.000303 0.000207 0.000144 0.000290 0.000431 0.000201 0.000279
Cytoplasm 0.195989 0.054145 0.043001 0.006197 0.036388 0.017605 0.007584 0.003101 0.048762 0.036616 0.019841 0.005070
Cytoplasmic Foci 0.045741 0.000937 0.000770 0.001598 0.000865 0.001101 0.000045 0.001170 0.004344 0.001016 0.000296 0.001442
Eisosomes 0.000082 0.000019 0.000018 0.000043 0.000018 0.000025 0.000030 0.000032 0.000023 0.000021 0.000026 0.000039
Endoplasmic Reticulum 0.004535 0.004887 0.005389 0.002176 0.006116 0.006481 0.003786 0.001358 0.005993 0.005651 0.004341 0.001878
Endosome 0.011680 0.000703 0.000474 0.002594 0.000613 0.001081 0.000266 0.003052 0.001471 0.000884 0.000338 0.002761
Golgi 0.000960 0.000792 0.000231 0.003398 0.000139 0.000388 0.000076 0.000676 0.000203 0.000598 0.000129 0.002407
Lipid Particles 0.005503 0.000207 0.000588 0.000263 0.000239 0.000219 0.000076 0.000120 0.000647 0.000213 0.000253 0.000211
Mitochondria 0.006889 0.001140 0.001520 0.003850 0.001737 0.001555 0.001543 0.003093 0.002137 0.001339 0.001535 0.003575
Mitotic Spindle 0.002915 0.001219 0.000713 0.012964 0.001707 0.004987 0.002221 0.014477 0.001801 0.003026 0.001699 0.013515
None 0.008178 0.008314 0.004323 0.005752 0.004076 0.003665 0.002975 0.002516 0.004394 0.006084 0.003442 0.004573
Nuclear Periphery 0.002548 0.000680 0.000711 0.002075 0.001052 0.000850 0.000926 0.000549 0.001168 0.000762 0.000851 0.001519
Nuclear Periphery Foci 0.001101 0.000545 0.000739 0.001513 0.000766 0.000792 0.000149 0.000290 0.000792 0.000663 0.000353 0.001067
Nucleolus 0.005987 0.002426 0.001619 0.006868 0.002243 0.004149 0.001735 0.006860 0.002533 0.003253 0.001695 0.006865
Nucleus 0.626541 0.903959 0.921820 0.908759 0.930679 0.938816 0.956479 0.925327 0.907098 0.920680 0.944485 0.914793
Peroxisomes 0.005359 0.000241 0.000262 0.000411 0.000137 0.000266 0.000087 0.000500 0.000542 0.000253 0.000148 0.000443
Vacuole 0.037793 0.004086 0.005182 0.003510 0.003114 0.004031 0.002598 0.002844 0.005802 0.004060 0.003492 0.003267
Vacuole Periphery 0.001651 0.000378 0.000301 0.002086 0.000361 0.000614 0.000440 0.002171 0.000461 0.000491 0.000392 0.002117

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.10 -1.35 -1.23 -3.35 0.12 -1.40 -7.88 -6.41 -5.89 -0.42 -2.13 -8.58 -5.77 -5.00 -0.68
Bud Neck 1.78 2.00 -1.23 -8.62 -8.32 -2.37 -7.32 -9.91 -8.49 -4.81 -2.17 -4.99 -12.99 -11.92 -8.92
Bud Site 2.29 2.37 2.09 -0.84 -1.01 -1.84 -1.58 -2.70 -1.52 -1.83 -1.74 -0.71 -3.29 -1.75 -2.28
Cell Periphery -2.23 1.45 0.38 2.29 -0.69 -0.17 3.17 4.31 3.17 1.55 -2.26 3.39 1.40 2.85 -0.39
Cytoplasm 6.90 7.65 9.40 12.33 8.10 6.17 11.34 13.65 7.66 4.19 3.43 9.47 15.07 13.99 8.24
Cytoplasmic Foci 6.49 6.53 6.49 0.14 -0.70 -0.55 5.24 0.74 1.02 -2.51 5.12 6.60 5.45 0.73 -2.68
Eisosomes 6.36 6.13 4.38 -7.76 -6.35 -3.08 -8.85 -8.66 -4.36 -1.22 1.32 -2.85 -6.63 -8.38 -4.86
Endoplasmic Reticulum -0.22 -1.06 2.19 11.36 10.36 -0.87 6.34 12.30 11.14 8.21 1.13 4.21 14.48 15.72 13.85
Endosome 3.02 3.08 2.75 -2.26 -2.90 -2.06 4.22 -1.34 -0.81 -1.74 1.82 3.80 -0.45 -1.89 -3.31
Golgi 0.17 1.11 -1.11 -1.31 -2.22 -1.33 0.84 -2.17 -0.43 -2.81 -1.31 0.79 -2.42 -1.50 -2.58
Lipid Particles 3.19 2.94 3.21 0.43 1.23 0.73 3.13 2.58 1.85 -0.16 3.19 2.38 3.60 1.22 0.95
Mitochondria 1.50 1.38 0.86 -4.22 -3.32 0.21 -0.10 -1.59 -2.51 -2.50 1.09 0.58 -1.56 -4.68 -4.04
Mitotic Spindle 0.91 0.84 -3.32 -4.75 -4.61 -1.89 -1.02 -3.68 -2.38 -3.27 -1.20 -0.59 -5.53 -4.78 -5.33
None 0.03 1.94 1.68 3.04 -0.46 0.62 1.76 2.47 1.81 0.96 -2.28 1.78 0.85 2.93 -0.64
Nuclear Periphery 1.56 1.47 0.69 -2.87 -2.59 1.53 -0.27 2.15 0.77 1.44 3.07 0.88 -0.72 -2.50 -1.29
Nuclear Periphery Foci 1.16 0.06 0.29 -1.00 0.18 0.38 3.02 2.73 1.91 -0.55 1.00 1.55 0.87 0.02 -0.66
Nucleolus 1.66 1.92 -0.75 -5.03 -5.16 -2.01 0.62 -4.84 -3.45 -5.15 -1.06 1.29 -6.29 -5.62 -7.52
Nucleus -9.85 -10.49 -10.34 -1.98 0.74 -1.58 -5.37 0.90 2.02 4.48 -2.58 -7.28 -2.33 0.11 4.95
Peroxisomes 2.73 2.71 2.69 -0.86 -0.37 -1.24 0.93 -2.06 -1.19 -2.41 1.82 2.44 1.01 -1.42 -2.68
Vacuole 4.30 4.08 4.50 1.67 3.73 -0.73 -0.27 0.90 1.46 1.02 1.96 1.63 3.58 2.14 2.48
Vacuole Periphery 2.62 2.83 0.41 -2.14 -2.37 -1.04 0.12 -1.64 -1.21 -1.63 -0.22 0.72 -2.34 -2.31 -2.69
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transport adaptor or symportin; facilitates synchronized nuclear coimport of the two 5S-rRNA binding proteins Rpl5p and Rpl11p; binds to nascent Rpl5p during translation; required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
Localization
Cell Percentages nucleus (68%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Syo1

Syo1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Syo1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available