Standard name
Human Ortholog
Description Component of the Rpd3L histone deacetylase complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 0.06 0.06 0 0 0 0 0 0.08 0.12 0.78 0.72 0.7 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.18 0 0 0 0 0.06 0 0.13 0.06 0.15 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.88 0.87 0.85 0.89 0.91 0.87 0.78 0.83 0.65 0.73 0.68 0.73 0.89 0.89 0.79 0.05 0.08 0.11 0.87 0.85 0.77 0.8 0.83 0.71
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.27 0.17 0.18 0.23 0.07 0.16 0.22 0.24 0.45 0.4 0.47 0.51 0.26 0.11 0.13 0 0 0 0.12 0.07 0.14 0.13 0.11 0.18
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.23 0.25 0.33 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0
Bud 0 0 2 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 5 0 0 0 0
Bud Neck 0 0 0 1 0 1 0 1 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 2 2 5 3 3 2 0 0 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 7 3 3 5 8 10 16 10 8 6 1 3 28 46 104 97 86 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 10 5 3 0 0 0 0 0 2
Endosome 0 1 1 0 0 0 0 0 0 0 0 0 0 0 4 4 8 2 0 1 2 1 0 2
Golgi 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1
Mitochondria 2 44 1 4 0 6 10 4 32 13 27 9 4 6 10 4 1 3 0 4 1 0 0 1
Nucleus 116 209 131 87 97 167 137 235 159 162 122 77 131 327 307 7 11 13 116 207 140 140 178 147
Nuclear Periphery 0 1 0 0 0 1 2 2 3 0 0 1 1 1 2 0 1 1 0 0 0 0 0 0
Nucleolus 36 40 27 23 7 31 39 67 111 88 84 54 38 42 49 0 0 0 15 17 25 23 23 37
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 1 1 0 0 3 3 5 0 2 1 0 3 5 12 4 1 1 0 0 0 1 1 2
Vac/Vac Membrane 1 4 4 0 0 2 5 1 5 3 6 1 0 1 4 31 34 41 0 5 5 6 4 6
Unique Cell Count 132 239 154 98 107 193 175 284 244 222 179 106 147 369 391 134 134 123 134 244 181 176 215 208
Labelled Cell Count 156 307 171 119 109 221 209 333 326 280 253 145 180 410 435 166 158 150 134 244 181 176 215 208


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.7 5.9 8.1 7.3 9.1 7.7 7.4 7.7 6.7 7.0 6.1 6.6 7.5 7.4 6.9 5.3 6.5 6.5 7.8 8.5 8.8
Std Deviation (1e-4) 1.6 1.1 1.8 1.6 2.7 2.9 2.8 2.2 2.4 2.3 2.2 2.3 1.9 1.8 2.0 1.0 1.1 1.3 1.6 2.1 2.5
Intensity Change (Log2) – – – -0.16 0.16 -0.08 -0.14 -0.06 -0.28 -0.21 -0.4 -0.3 -0.11 -0.13 -0.23 -0.61 -0.32 -0.31 -0.05 0.08 0.12

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 1.7 1.8 1.2 0 0 0 0 2.5 3.6 13.3 12.5 12.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 2.6 0 4.4 2.6 4.7 0 0 0 0 0 0 0
Nucleus 0.8 1.3 0.4 -1.6 -0.6 -4.3 -2.8 -3.6 -2.5 1.0 1.1 -1.7 -13.5 -13.0 -12.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.2 -2.6 -0.4 1.1 1.5 5.7 4.6 5.7 5.7 1.8 -1.9 -1.5 -5.1 -5.1 -4.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 5.3 5.7 6.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.3714 6.7924 6.9072 6.1937 6.4806 6.6062 4.8806 5.8113 4.7495 4.8715 4.0861 4.9382 3.3818 2.717 2.5209 2.656 2.5826 2.2928
Actin 0.0349 0 0.0048 0 0.0004 0.0001 0.0804 0 0.0147 0.0465 0.0576 0.0006 0 0 0 0 0 0
Bud 0.0004 0 0.0001 0 0.0004 0 0.0012 0.0003 0.0002 0.0004 0.003 0.0001 0 0 0 0 0 0.0006
Bud Neck 0.0015 0 0.0002 0.0002 0.0018 0.001 0.0017 0.0006 0.0002 0.0003 0.0016 0.0009 0.0001 0 0 0 0.0005 0.0009
Bud Periphery 0.0008 0 0.0002 0.0001 0.0011 0.0001 0.0019 0.0005 0.0004 0.0004 0.0059 0.0001 0 0 0 0 0.0001 0.0004
Bud Site 0.0059 0 0.0003 0.0001 0.0022 0.0001 0.0029 0.0068 0.0004 0.0007 0.0064 0.0001 0.0001 0 0 0 0.0001 0.0001
Cell Periphery 0.0005 0 0.0002 0 0.0003 0 0.0004 0.0001 0.0001 0 0.0003 0 0 0 0 0 0 0.0001
Cytoplasm 0.002 0 0.0006 0 0.0004 0 0.0322 0.0001 0.0015 0.0023 0.0008 0.0003 0 0 0 0 0 0.0008
Cytoplasmic Foci 0.0137 0 0.0007 0 0.0078 0.0048 0.0153 0.001 0.003 0.0095 0.0235 0.0013 0 0 0 0 0 0.0014
Eisosomes 0.0005 0 0 0 0 0 0.0012 0 0.0001 0.0001 0.0002 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0025 0 0.0004 0 0.0004 0 0.007 0 0.0006 0.0037 0.0009 0.0001 0 0 0 0 0 0
Endosome 0.0108 0 0.0011 0 0.0018 0.0006 0.0408 0.0011 0.0041 0.0249 0.033 0.0027 0 0 0 0 0 0
Golgi 0.0034 0 0.0005 0 0.0006 0.0004 0.01 0.0004 0.0021 0.0139 0.0395 0.0008 0 0 0 0 0 0
Lipid Particles 0.0226 0 0.0005 0 0.0035 0.0015 0.018 0.0004 0.0125 0.0068 0.0482 0.0053 0 0 0 0 0 0
Mitochondria 0.0031 0 0.0037 0.0003 0.003 0.0057 0.0112 0.0002 0.0044 0.0044 0.0351 0.0009 0.0003 0.0001 0.0001 0 0.0002 0.0027
None 0.004 0 0.0009 0 0.0001 0.0001 0.0349 0 0.0138 0.0007 0.0008 0.0002 0 0 0 0 0 0.0009
Nuclear Periphery 0.0127 0.0002 0.0029 0.0009 0.0013 0.0002 0.0423 0.0003 0.0036 0.0027 0.004 0.0059 0.0001 0.0001 0.0001 0.0001 0.0006 0.0001
Nucleolus 0.0655 0.0238 0.0274 0.0549 0.1486 0.1438 0.0298 0.0349 0.0205 0.017 0.1135 0.1141 0.0414 0.0284 0.0328 0.0198 0.24 0.128
Nucleus 0.7884 0.9755 0.9444 0.9425 0.7934 0.8375 0.6406 0.9494 0.9105 0.858 0.5782 0.8581 0.9578 0.9713 0.9666 0.9796 0.7554 0.8621
Peroxisomes 0.0052 0 0.0041 0 0.0267 0.0002 0.0076 0.0002 0.0012 0.0051 0.0295 0.0009 0 0 0 0 0 0.0001
Punctate Nuclear 0.0193 0.0004 0.0045 0.0006 0.0023 0.0033 0.0143 0.0022 0.004 0.0018 0.0124 0.0073 0.0001 0.0001 0.0002 0.0003 0.0028 0.0011
Vacuole 0.0013 0 0.0013 0.0001 0.0034 0.0002 0.003 0.0012 0.0009 0.0003 0.0039 0.0002 0.0001 0 0 0 0.0001 0.0003
Vacuole Periphery 0.0009 0 0.0012 0.0001 0.0006 0.0002 0.0032 0.0001 0.0009 0.0004 0.0016 0.0002 0 0 0 0 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.0655 18.9473 14.0597 21.3944 25.8642 11.2149 26.2009 24.7193 19.8512 26.3153
Translational Efficiency 0.7235 1.1272 1.2799 0.769 0.6978 1.746 0.7312 0.9999 0.9592 0.7773

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1598 1891 2321 1800 1555 1397 410 1358 3153 3288 2731 3158

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.34 989.64 1017.14 987.28 722.58 832.82 1069.35 1005.76 738.17 923.01 1024.98 995.23
Standard Deviation 145.19 156.46 142.56 144.91 121.31 137.94 140.03 148.21 134.83 167.85 143.40 146.62
Intensity Change Log 2 — 0.393603 0.433145 0.390158 — 0.204847 0.565505 0.477057 — 0.304273 0.499463 0.433356

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000465 0.000478 0.000739 0.002271 0.000618 0.000557 0.001366 0.001092 0.000540 0.000511 0.000833 0.001764
Bud Neck 0.004444 0.013974 0.030057 0.048887 0.006087 0.006840 0.016637 0.033840 0.005255 0.010943 0.028042 0.042417
Bud Site 0.000725 0.000880 0.001928 0.014129 0.001091 0.001176 0.001598 0.004957 0.000905 0.001006 0.001878 0.010185
Cell Periphery 0.000133 0.000049 0.000043 0.000182 0.000166 0.000164 0.000041 0.000117 0.000149 0.000098 0.000043 0.000154
Cytoplasm 0.003593 0.001096 0.000370 0.007530 0.004028 0.002205 0.000201 0.004343 0.003807 0.001568 0.000345 0.006159
Cytoplasmic Foci 0.000646 0.000057 0.000012 0.002905 0.001138 0.002165 0.000036 0.001147 0.000888 0.000952 0.000016 0.002149
Eisosomes 0.000032 0.000052 0.000061 0.000049 0.000036 0.000040 0.000073 0.000044 0.000034 0.000047 0.000063 0.000047
Endoplasmic Reticulum 0.002539 0.001797 0.001684 0.005596 0.003280 0.002940 0.003038 0.003672 0.002904 0.002283 0.001887 0.004768
Endosome 0.000208 0.000118 0.000102 0.005904 0.000356 0.000877 0.000100 0.000867 0.000281 0.000440 0.000101 0.003738
Golgi 0.000431 0.000155 0.000122 0.003117 0.000691 0.000900 0.000198 0.001863 0.000559 0.000471 0.000133 0.002578
Lipid Particles 0.000226 0.000039 0.000021 0.000449 0.000532 0.001063 0.000069 0.000089 0.000377 0.000474 0.000029 0.000294
Mitochondria 0.001336 0.000836 0.002031 0.008289 0.001411 0.002546 0.001274 0.004305 0.001373 0.001562 0.001917 0.006576
Mitotic Spindle 0.001206 0.001417 0.001670 0.053837 0.001544 0.001632 0.003878 0.013856 0.001373 0.001508 0.002001 0.036644
None 0.018320 0.001581 0.001146 0.005419 0.013131 0.010665 0.002894 0.005550 0.015761 0.005441 0.001409 0.005475
Nuclear Periphery 0.000115 0.000087 0.000246 0.007647 0.000173 0.000226 0.000122 0.000875 0.000144 0.000146 0.000228 0.004735
Nuclear Periphery Foci 0.000667 0.000156 0.000066 0.002897 0.000955 0.000794 0.000107 0.000787 0.000809 0.000427 0.000072 0.001990
Nucleolus 0.088688 0.119185 0.092074 0.032472 0.093059 0.098049 0.098188 0.045775 0.090843 0.110205 0.092992 0.038193
Nucleus 0.875081 0.856895 0.866238 0.780086 0.870052 0.863922 0.867074 0.873278 0.872601 0.859881 0.866364 0.820160
Peroxisomes 0.000729 0.000657 0.000693 0.001045 0.001024 0.001487 0.002254 0.000626 0.000874 0.001010 0.000927 0.000865
Vacuole 0.000256 0.000258 0.000395 0.012425 0.000368 0.000960 0.000673 0.002354 0.000312 0.000556 0.000436 0.008094
Vacuole Periphery 0.000161 0.000233 0.000301 0.004862 0.000261 0.000792 0.000179 0.000564 0.000210 0.000471 0.000283 0.003014

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.26 -7.55 -6.04 -6.05 -4.64 1.07 -10.23 -11.47 -13.76 2.35 0.88 -9.77 -8.08 -8.39 -5.33
Bud Neck -14.17 -25.94 -23.08 -17.34 -7.47 -0.96 -9.94 -18.64 -17.59 -9.31 -10.95 -26.66 -29.44 -24.24 -8.94
Bud Site -1.15 -6.65 -8.77 -8.66 -7.30 -0.32 -5.63 -6.55 -6.30 -4.85 -0.74 -6.91 -10.59 -10.45 -8.43
Cell Periphery 4.19 4.48 -0.75 -9.10 -10.56 0.09 5.66 2.29 1.53 -5.82 2.67 7.14 1.05 -2.36 -11.25
Cytoplasm 2.77 4.06 -4.23 -8.21 -10.42 1.81 4.24 -0.37 -2.32 -4.91 3.31 5.68 -3.36 -7.71 -10.80
Cytoplasmic Foci 1.95 2.10 -1.30 -3.74 -3.89 -1.14 2.79 1.22 2.24 -2.53 0.06 3.52 -0.06 -0.13 -4.67
Eisosomes -10.21 -15.38 -10.41 -0.50 4.47 -1.17 -12.07 -6.61 -4.42 8.32 -7.97 -17.99 -11.99 -3.19 7.57
Endoplasmic Reticulum 4.93 4.50 -12.09 -14.74 -14.46 1.23 -1.16 -5.32 -6.00 -3.55 4.15 5.64 -12.66 -15.43 -16.55
Endosome 2.12 2.81 -4.83 -4.98 -5.00 -2.40 4.30 -2.07 0.54 -3.52 -1.66 5.08 -5.14 -4.52 -5.67
Golgi 1.31 1.39 -2.12 -3.00 -3.04 -0.47 1.62 -0.78 -0.42 -1.82 0.45 2.33 -2.06 -2.44 -3.59
Lipid Particles 2.41 2.60 -1.77 -8.17 -8.89 -0.92 1.30 1.02 1.89 -3.09 -0.35 2.01 0.45 0.86 -10.19
Mitochondria 0.85 -1.38 -6.86 -10.93 -7.45 -1.53 -0.27 -3.32 -1.46 -3.67 -0.46 -1.74 -7.66 -7.85 -7.10
Mitotic Spindle -0.19 -1.20 -11.94 -11.97 -11.69 -0.13 -1.15 -6.34 -6.19 -4.81 -0.21 -1.58 -13.45 -13.39 -12.83
None 7.80 8.06 5.86 -6.26 -8.03 1.16 5.96 4.85 3.88 -1.76 6.98 10.65 7.59 0.45 -7.65
Nuclear Periphery 1.03 -3.24 -5.83 -5.85 -5.59 -1.14 -0.30 -5.87 -5.57 -5.86 -0.35 -2.77 -6.67 -6.66 -6.35
Nuclear Periphery Foci 3.28 3.90 -3.48 -5.72 -6.05 0.60 3.32 0.64 0.14 -2.06 2.37 5.04 -2.08 -4.15 -6.15
Nucleolus -7.27 -2.16 16.11 23.78 18.85 -1.09 -1.31 12.24 13.26 8.54 -6.40 -2.18 20.39 26.73 19.89
Nucleus 3.47 3.65 10.02 8.08 7.99 0.91 1.52 2.24 1.38 0.37 3.16 3.93 9.48 7.29 6.40
Peroxisomes 0.71 -0.16 0.18 -0.80 0.54 -1.06 -4.86 2.07 2.10 8.06 -0.60 -0.95 1.66 1.81 4.28
Vacuole -0.12 -2.44 -9.31 -9.28 -9.13 -2.20 -2.87 -4.92 -4.37 -4.20 -1.95 -3.05 -10.40 -10.06 -10.09
Vacuole Periphery -1.89 -3.89 -4.81 -4.64 -4.50 -2.40 1.87 -2.11 1.38 -2.84 -2.69 -2.30 -5.04 -3.83 -4.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the Rpd3L histone deacetylase complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Rxt3

Rxt3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rxt3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available