Standard name
Human Ortholog
Description FG-nucleoporin component of central core of nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport; induces membrane tubulation, which may contribute to nuclear pore assembly; ASM4 has a paralog, NUP53, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 0 0 – 0 0 0 0.07 0.11 0.15 0.14 0.11 0.13 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.08 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.08 0.05 0 0 0.05 0.05 0.06 0.07
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.06 0.09 0.15 0.15 0.39 0.42 0.41 – 0.51 0.52 0.47 0 0 0 0.08 0.08 0.11 0 0 0 0.05 0.09 0.1
Nucleus 0.13 0.15 0.07 0 0.06 0.06 0.09 0.06 – 0.08 0.09 0.08 0.09 0.05 0.05 0.15 0.11 0.14 0.05 0.06 0 0 0 0
Nuclear Periphery 0.68 0.67 0.78 0.78 0.7 0.62 0.56 0.51 – 0.52 0.51 0.51 0.77 0.75 0.64 0.54 0.55 0.57 0.76 0.7 0.83 0.75 0.76 0.72
Nucleolus 0.15 0.08 0.15 0.2 0.2 0.27 0.28 0.33 – 0.32 0.32 0.34 0.13 0.08 0.09 0.13 0.11 0.11 0.06 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.29 0.27 0.14 0.08 0.09 0 0 0.06 – 0 0 0.05 0.21 0.21 0.23 0.3 0.34 0.27 0.06 0.12 0 0.06 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 1 0 1 0 0 0 0 0 2 1 3 3 4
Bud 0 0 0 1 1 2 1 4 – 2 3 2 1 1 0 0 0 0 3 6 3 2 5 3
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 0 0 0 2 7 3 – 9 8 3 0 5 4 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 – 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 13 6 10 14 9 8 11 – 6 1 7 22 74 72 26 26 15 0 2 1 0 1 0
Endoplasmic Reticulum 0 3 0 0 2 0 2 19 – 1 2 1 0 2 1 4 6 3 0 0 0 1 2 2
Endosome 2 0 34 2 11 7 4 9 – 1 3 7 7 23 15 11 19 6 7 15 23 23 44 61
Golgi 0 0 2 0 0 0 0 0 – 0 0 0 0 1 0 0 1 0 0 1 3 4 5 6
Mitochondria 1 26 38 39 45 168 230 230 – 255 223 191 2 1 2 15 19 13 6 7 15 23 67 79
Nucleus 37 61 30 8 19 26 51 32 – 41 37 31 26 35 27 28 26 16 19 31 6 4 3 4
Nuclear Periphery 190 279 329 204 218 266 308 286 – 258 221 206 236 517 317 99 132 65 270 364 416 334 564 597
Nucleolus 41 32 64 52 61 118 156 183 – 158 137 138 39 58 45 24 27 13 20 22 9 9 8 14
Peroxisomes 0 0 0 0 0 0 0 0 – 0 1 1 0 2 4 0 0 0 0 0 0 6 8 12
SpindlePole 1 0 4 1 3 2 2 1 – 3 2 1 1 18 27 0 1 0 3 1 4 3 4 8
Vac/Vac Membrane 81 111 60 20 27 19 21 35 – 12 17 21 65 143 111 55 82 31 21 61 15 25 20 27
Unique Cell Count 278 418 422 263 310 431 554 556 498 432 403 305 686 492 184 240 115 355 522 505 444 745 828
Labelled Cell Count 355 526 567 337 401 619 790 813 747 655 611 399 881 625 262 339 162 355 522 505 444 745 828


Nuclear Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.2 9.9 9.0 8.5 7.7 6.6 6.3 6.6 – 6.0 6.2 6.6 10.3 10.4 10.5 7.3 8.7 9.2 11.4 11.8 12.1
Std Deviation (1e-4) 2.3 3.0 2.3 2.5 2.2 1.8 1.8 1.9 – 2.1 2.0 2.3 2.2 2.7 2.8 1.7 2.2 2.3 2.2 2.0 2.5
Intensity Change (Log2) – – – -0.08 -0.22 -0.43 -0.5 -0.44 – -0.57 -0.54 -0.45 0.21 0.22 0.23 -0.29 -0.03 0.04 0.35 0.4 0.44

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 2.0 2.5 0.7 0 0.7 – -0.3 0 0.4 4.0 5.8 7.1 6.4 5.4 0
Endoplasmic Reticulum 0 0 0 0 3.8 – 0 0 0 0 0 0 0 0 0
Endosome -4.2 -2.5 -4.4 -5.9 -4.9 – -6.2 -5.3 -4.2 -3.3 -3.4 -3.4 -0.9 -0.1 -1.0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 2.3 2.3 10.2 11.3 11.2 – 13.7 13.5 12.3 -4.9 -7.8 -6.3 -0.3 -0.5 0.7
Nucleus -2.3 -0.5 -0.6 1.2 -0.9 – 0.6 0.8 0.3 0.7 -1.4 -1.0 3.1 1.7 2.3
Nuclear Periphery -0.1 -2.4 -5.2 -7.3 -8.5 – -8.2 -8.2 -8.1 -0.2 -1.0 -4.5 -6.0 -6.2 -4.6
Nucleolus 1.6 1.6 4.4 4.8 6.3 – 5.8 5.7 6.4 -0.9 -3.5 -2.8 -0.7 -1.4 -1.0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 1.9 3.8 0 0 0
Vacuole -2.6 -2.3 -4.9 -5.9 -4.1 – -6.6 -5.2 -4.3 2.5 2.8 3.2 4.5 6.0 3.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.1821 7.311 7.91 7.4 8.1585 7.9786 10.4364 9.5715 9.9874 10.5565 9.1311 9.8314 11.0107 10.1428 10.0018 10.1866 10.3859 9.953
Actin 0.0001 0.0001 0.0001 0.0003 0.0002 0.0002 0.0009 0.0001 0.0001 0.0002 0.0002 0.0001 0.0008 0.0002 0.0001 0.0003 0.0001 0.0001
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0.0014 0 0 0 0 0
Bud Neck 0 0.0001 0 0 0.0001 0.0001 0.0004 0 0 0 0 0 0.0001 0 0 0 0.0001 0
Bud Periphery 0 0 0 0 0.0001 0.0001 0.0001 0 0 0 0 0 0.0003 0 0 0 0 0
Bud Site 0 0.0003 0 0 0.0001 0 0.0022 0 0 0 0 0 0.0002 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0.0002 0 0 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0001 0.006 0.0001 0.0002 0.0001 0.0002 0.0003 0 0 0.0001 0 0 0.0021 0.0001 0 0 0 0
Cytoplasmic Foci 0 0.0002 0 0 0.0118 0 0.0009 0 0 0 0.0002 0 0.0034 0 0 0 0.0001 0
Eisosomes 0 0 0 0 0 0 0.0001 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0002 0.0007 0.0002 0.0002 0.0003 0.0001 0.0004 0.0003 0.0002 0.0003 0.0003 0.0003 0.0011 0.0002 0.0003 0.0005 0.0001 0.0001
Endosome 0.0002 0.002 0.0002 0.0001 0.0008 0.0002 0.0017 0.0001 0.0001 0.0002 0.0005 0.0004 0.0027 0.0001 0.0001 0.0002 0.0002 0.0001
Golgi 0 0 0 0 0.0003 0 0.0003 0 0 0 0.0002 0.0001 0.0004 0 0 0.0001 0.0002 0
Lipid Particles 0.0002 0.0002 0.0002 0.0001 0.0235 0.0004 0.0035 0.0004 0.0003 0.0002 0.0031 0.0005 0.0035 0.0002 0.0006 0.0005 0.0027 0.0004
Mitochondria 0.0003 0.0002 0.0002 0.0006 0.0009 0.0004 0.0011 0.0001 0.0002 0.0003 0.0017 0.0009 0.0011 0.0002 0.0003 0.0004 0.0009 0.0002
None 0.0001 0.0002 0 0.0001 0.0001 0.0001 0.0005 0 0 0.0001 0.0002 0 0.0028 0 0.0001 0.0001 0.0001 0
Nuclear Periphery 0.8929 0.6963 0.8384 0.916 0.8383 0.8985 0.9426 0.9178 0.9393 0.9005 0.9219 0.9741 0.926 0.924 0.9239 0.9654 0.8893 0.9591
Nucleolus 0.0024 0.0142 0.0063 0.0012 0.0292 0.008 0.001 0.0021 0.005 0.0006 0.0091 0.0008 0.0031 0.0054 0.0035 0.0005 0.0144 0.0015
Nucleus 0.0909 0.2567 0.1384 0.068 0.0732 0.082 0.0293 0.062 0.0407 0.0838 0.0417 0.0146 0.03 0.0549 0.0524 0.0125 0.0779 0.0299
Peroxisomes 0 0 0 0 0.0001 0 0.0008 0 0 0 0.0001 0 0.0001 0 0 0 0 0
Punctate Nuclear 0.0019 0.0049 0.0019 0.0015 0.0044 0.0019 0.0029 0.0054 0.0008 0.0009 0.0033 0.0006 0.0055 0.0018 0.0013 0.0015 0.0035 0.001
Vacuole 0.0003 0.0082 0.0007 0.0001 0.0009 0.0004 0.0004 0.0002 0.0002 0.0001 0.0004 0.0002 0.0019 0.0002 0.0002 0.0002 0.0002 0.0001
Vacuole Periphery 0.0105 0.0097 0.0132 0.0117 0.0156 0.0074 0.0104 0.0113 0.0131 0.0128 0.0171 0.0075 0.0133 0.0126 0.0171 0.0179 0.0099 0.0075

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.2489 20.5107 17.5258 26.2976 20.7335 14.5927 21.5238 26.9335 20.1477 25.5794
Translational Efficiency 1.1221 1.1032 1.2706 0.7213 1.1893 1.7179 1.0583 0.8209 1.1492 0.9996

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
130 822 105 1062 1616 1116 827 927 1746 1938 932 1989

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1005.61 1056.95 1140.31 1130.60 780.85 986.67 1169.37 1089.41 797.58 1016.48 1166.10 1111.40
Standard Deviation 161.01 193.02 248.71 194.20 142.92 169.42 192.15 181.55 155.94 183.13 199.54 189.53
Intensity Change Log 2 — 0.071836 0.181355 0.169018 — 0.337522 0.582614 0.480430 — 0.194023 0.370589 0.313463

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000935 0.000304 0.001367 0.000278 0.000643 0.000574 0.000383 0.000277 0.000665 0.000459 0.000494 0.000278
Bud Neck 0.003181 0.000699 0.002961 0.002397 0.001011 0.000563 0.000835 0.001670 0.001172 0.000621 0.001075 0.002058
Bud Site 0.003691 0.000095 0.001492 0.000587 0.000953 0.000296 0.000101 0.000465 0.001157 0.000211 0.000257 0.000530
Cell Periphery 0.000087 0.000028 0.000201 0.000035 0.000157 0.000060 0.000026 0.000032 0.000152 0.000046 0.000045 0.000034
Cytoplasm 0.008701 0.000490 0.049172 0.001208 0.003860 0.001879 0.002872 0.000837 0.004220 0.001290 0.008088 0.001035
Cytoplasmic Foci 0.006917 0.000299 0.013351 0.001079 0.001855 0.001117 0.000261 0.001810 0.002232 0.000770 0.001736 0.001420
Eisosomes 0.000020 0.000004 0.000093 0.000005 0.000016 0.000012 0.000004 0.000004 0.000016 0.000008 0.000014 0.000005
Endoplasmic Reticulum 0.013455 0.004723 0.009012 0.001855 0.009254 0.007206 0.001851 0.003299 0.009567 0.006153 0.002658 0.002528
Endosome 0.004987 0.000998 0.003279 0.001992 0.003131 0.001673 0.000347 0.002895 0.003269 0.001387 0.000677 0.002413
Golgi 0.006954 0.000420 0.000333 0.000950 0.000908 0.000937 0.000132 0.002382 0.001358 0.000717 0.000155 0.001617
Lipid Particles 0.003721 0.000640 0.003410 0.001281 0.003417 0.001768 0.000835 0.001358 0.003440 0.001290 0.001125 0.001317
Mitochondria 0.015178 0.002180 0.002918 0.002973 0.007340 0.005468 0.001859 0.002428 0.007924 0.004073 0.001978 0.002719
Mitotic Spindle 0.069368 0.004429 0.014881 0.045679 0.001709 0.006818 0.012274 0.046841 0.006747 0.005805 0.012568 0.046221
None 0.001282 0.001191 0.003996 0.000344 0.006257 0.007209 0.000379 0.000491 0.005887 0.004657 0.000786 0.000413
Nuclear Periphery 0.349363 0.496825 0.286516 0.516634 0.425784 0.424031 0.625728 0.468363 0.420094 0.454907 0.587512 0.494137
Nuclear Periphery Foci 0.342947 0.409851 0.179584 0.377930 0.413932 0.349397 0.263688 0.414056 0.408647 0.375038 0.254213 0.394767
Nucleolus 0.044912 0.027743 0.083735 0.011644 0.051109 0.062708 0.036238 0.011852 0.050647 0.047878 0.041589 0.011741
Nucleus 0.094945 0.038519 0.316078 0.017635 0.055174 0.121630 0.048580 0.031270 0.058135 0.086379 0.078717 0.023990
Peroxisomes 0.001293 0.000247 0.002051 0.000241 0.000964 0.000830 0.000341 0.000762 0.000989 0.000583 0.000534 0.000484
Vacuole 0.014988 0.004541 0.024008 0.005714 0.005558 0.002363 0.000979 0.003673 0.006260 0.003287 0.003574 0.004763
Vacuole Periphery 0.013076 0.005774 0.001563 0.009537 0.006965 0.003460 0.002286 0.005235 0.007420 0.004442 0.002205 0.007532

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.39 -1.29 2.39 0.10 4.30 0.84 3.47 5.68 5.14 1.71 3.43 1.84 6.13 3.94 3.66
Bud Neck 2.76 -0.26 0.62 -4.41 0.82 1.77 0.22 -2.42 -3.92 -2.88 2.34 -0.32 -3.35 -5.94 -3.37
Bud Site 2.34 1.07 1.95 -2.36 1.73 1.55 2.56 0.88 -0.86 -2.29 2.79 2.47 1.42 -2.06 -1.54
Cell Periphery 2.72 -3.35 2.30 -1.58 5.64 4.19 5.84 5.79 3.08 -0.62 5.18 4.85 5.90 2.01 1.98
Cytoplasm 2.08 -3.37 1.64 -2.40 4.14 1.62 0.06 3.31 2.34 2.16 3.00 -2.44 2.73 -0.33 4.01
Cytoplasmic Foci 1.80 -1.70 1.55 -2.03 3.94 1.09 3.53 0.13 -0.82 -2.68 2.56 0.47 1.31 -1.49 0.87
Eisosomes 2.92 -4.36 2.62 -0.92 5.69 1.61 6.17 5.86 5.41 -0.34 4.04 0.31 5.79 3.10 4.29
Endoplasmic Reticulum 1.32 0.55 1.77 4.62 5.92 2.17 11.43 8.47 5.05 -3.95 3.84 8.71 9.07 7.08 0.62
Endosome 3.25 0.75 2.30 -2.18 2.19 1.97 4.38 0.22 -1.38 -3.19 2.96 4.17 1.10 -2.14 -3.73
Golgi 1.35 1.37 1.23 -1.40 -1.93 -0.03 3.72 -1.52 -1.38 -2.42 1.29 3.05 -0.47 -1.67 -3.18
Lipid Particles 2.40 -0.30 1.78 -1.22 3.10 2.93 3.92 3.87 0.81 -0.89 4.71 3.65 4.19 -0.07 -0.20
Mitochondria 1.75 1.59 1.60 -1.12 0.01 1.61 6.08 5.69 2.92 -1.06 3.74 5.96 5.09 1.67 -1.28
Mitotic Spindle 4.34 3.45 1.69 -8.82 -4.47 -3.33 -4.97 -8.74 -7.53 -6.00 0.79 -2.64 -10.75 -11.45 -8.20
None 0.25 -1.69 1.70 1.03 2.54 -0.52 5.86 5.76 3.79 -0.42 0.81 5.35 5.94 3.93 2.04
Nuclear Periphery -5.58 1.59 -6.07 -1.10 -7.56 0.32 -16.89 -3.21 -3.21 12.12 -3.74 -13.68 -7.50 -3.87 8.07
Nuclear Periphery Foci -2.63 5.12 -1.35 3.31 -9.81 6.30 16.39 0.37 -5.21 -13.70 3.87 17.47 2.06 -1.99 -16.62
Nucleolus 2.15 -1.71 3.62 4.77 5.16 -2.50 3.19 10.93 11.55 6.17 0.69 2.14 12.23 12.36 8.04
Nucleus 3.36 -6.19 4.35 3.63 9.65 -8.31 0.46 3.86 10.62 2.83 -4.81 -3.43 7.30 11.52 8.34
Peroxisomes 1.59 -1.12 1.59 0.10 6.78 0.43 3.92 0.16 0.03 -0.82 2.22 2.85 1.36 0.26 0.01
Vacuole 2.12 -1.76 1.62 -1.58 3.22 3.10 4.28 1.09 -2.10 -3.41 2.79 1.07 0.39 -2.72 -0.79
Vacuole Periphery 1.12 1.83 0.51 -2.38 -6.25 3.51 5.68 1.58 -1.74 -3.43 2.96 5.88 -0.11 -3.28 -6.53
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description FG-nucleoporin component of central core of nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport; induces membrane tubulation, which may contribute to nuclear pore assembly; ASM4 has a paralog, NUP53, that arose from the whole genome duplication
Localization
Cell Percentages nuclear periphery (95%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Asm4

Asm4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Asm4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available