Standard name
Human Ortholog
Description Protein O-mannosyltransferase of the ER membrane; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues; 1 of 7 related proteins involved in O-glycosylation which is essential for cell wall rigidity; involved in ER quality control; amino terminus faces cytoplasm, carboxyl terminus faces ER lumen
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.07 0.05 0.05 0.06 0.1 0.1 0.08
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0.05 0.07 0.08 0 0.14 0.07 0.08 0 0.16 0 0 0 0.05 0.08 0.1
Cytoplasm 0.51 0.42 0.49 0.39 0.39 0.38 0.35 0.42 – 0.32 0.27 0.33 0.33 0.47 0.74 0.86 0.82 0.74 0.1 0.15 0.08 0.05 0.07 0.08
Endoplasmic Reticulum 0.4 0.48 0.3 0.27 0.18 0.18 0.14 0.05 – 0.18 0.15 0.07 0.58 0.46 0.25 0.05 0.1 0.05 0.7 0.57 0.67 0.51 0.52 0.51
Endosome 0 0 0.06 0 0.06 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.1 0.13 0.41 0.29 0.58 0.63 0.63 – 0.66 0.7 0.75 0 0 0 0.13 0.08 0.05 0.07 0.1 0.08 0.18 0.14 0.11
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.13 0 0.07 0 0.2 0 0.08 0.08 – 0.05 0 0.05 0.09 0 0 0.05 0 0 0 0 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 8 6 3 1 0 0 0 – 2 4 2 3 0 2 7 8 13 17 16 18 18 29 21
Bud 2 2 5 2 2 6 7 15 – 6 6 14 1 1 1 6 4 2 2 2 1 0 2 1
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 7 0 2 7 1 2 5 5
Bud Site 0 0 0 0 0 1 0 1 – 2 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 9 7 6 4 6 13 12 12 – 19 19 28 2 14 16 34 10 30 2 4 7 8 26 26
Cytoplasm 160 103 112 62 76 114 124 202 – 128 72 122 32 47 159 377 190 137 36 48 23 10 20 23
Endoplasmic Reticulum 125 120 69 43 35 54 48 24 – 71 41 26 56 46 54 22 23 10 269 181 202 96 159 143
Endosome 3 0 13 3 12 3 2 8 – 1 0 1 3 1 1 5 0 2 7 5 3 4 1 3
Golgi 5 0 1 0 0 0 0 0 – 0 0 0 1 0 0 1 0 2 4 4 2 5 4 2
Mitochondria 13 26 29 65 56 173 222 301 – 264 187 278 1 1 0 58 18 9 26 30 24 34 42 31
Nucleus 0 0 1 0 0 1 2 2 – 2 1 0 0 1 0 2 4 4 0 0 0 0 0 0
Nuclear Periphery 0 2 1 1 1 0 1 2 – 8 2 7 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 1 0 3 0 1 0 – 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
SpindlePole 2 0 2 0 0 0 0 0 – 0 0 1 0 0 1 2 2 2 0 0 0 0 0 0
Vac/Vac Membrane 42 7 17 6 39 12 30 38 – 20 3 17 9 3 3 20 2 5 8 10 8 6 12 17
Unique Cell Count 315 248 230 157 193 298 353 480 398 269 371 97 99 216 437 232 185 384 317 301 191 308 283
Labelled Cell Count 368 275 263 189 231 377 449 605 523 336 497 108 114 237 536 268 216 384 317 301 191 308 283


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.4 5.3 5.2 5.5 4.5 4.2 4.6 – 4.0 4.1 4.0 7.0 6.9 7.2 5.2 5.3 6.5 6.6 6.9 7.7
Std Deviation (1e-4) 0.8 0.9 1.5 1.3 1.3 1.2 1.0 1.3 – 0.8 0.7 0.9 0.8 0.9 1.2 1.4 0.8 1.2 1.2 1.1 1.6
Intensity Change (Log2) – – – -0.02 0.06 -0.23 -0.32 -0.21 – -0.39 -0.37 -0.4 0.42 0.38 0.44 -0.02 0.02 0.3 0.33 0.4 0.55

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0.5 2.1
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.3 0 0 0 – 0 0 0 0 4.0 2.3 2.7 1.0 4.9
Cytoplasm -1.8 -1.9 -2.4 -3.3 -1.7 – -4.1 -5.1 -3.9 -2.6 -0.2 5.4 10.4 7.5 5.2
Endoplasmic Reticulum -0.6 -2.8 0 0 0 – 0 0 0 4.7 2.9 -1.2 -8.9 -5.4 -6.3
Endosome -1.8 0.2 0 0 0 – 0 0 0 0 0 -3.1 -3.4 -3.7 -2.5
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 6.5 4.2 0 0 0 – 0 0 0 -3.3 -3.4 -5.4 0.2 -1.7 -2.7
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole -1.5 3.9 -1.7 0.5 0.2 – -1.2 -3.6 -1.4 0.6 -1.5 -3.1 -1.5 -3.5 -2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.6161 5.3538 5.9047 5.1702 5.1926 5.493 8.0111 8.6145 8.8389 8.6352 7.9961 7.9556 7.3664 7.4897 8.0524 7.9051 7.5202 7.4164
Actin 0.0012 0.006 0.01 0.0129 0.0022 0.0022 0.0028 0.0017 0.0015 0.0015 0.0018 0.0016 0.0033 0.002 0.0009 0.0009 0.0015 0.0022
Bud 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0 0.0002 0 0.0001 0 0 0 0 0 0.0001 0 0.0003
Bud Neck 0.0002 0.0008 0.0018 0.0185 0.0017 0.0026 0.0003 0.0007 0.0011 0.0027 0.003 0.0023 0.0003 0.0003 0.0008 0.0003 0.0004 0.0018
Bud Periphery 0.0002 0.0004 0.0004 0.0004 0.0004 0.0003 0.0001 0.0004 0.0002 0.0004 0.0002 0.0003 0.0001 0.0001 0.0001 0.0001 0 0.0004
Bud Site 0.0005 0.0088 0.0013 0.0012 0.0003 0.001 0.0003 0.0048 0.0005 0.0002 0.0001 0.0001 0.0006 0.0011 0.0005 0 0 0.0002
Cell Periphery 0.0032 0.0045 0.0027 0.0015 0.0015 0.0022 0.0072 0.0052 0.009 0.0126 0.0043 0.0054 0.0021 0.0039 0.0044 0.0032 0.0009 0.0057
Cytoplasm 0.0802 0.2088 0.1323 0.0786 0.0762 0.11 0.0565 0.0781 0.0544 0.048 0.1085 0.0766 0.0698 0.1086 0.0443 0.0252 0.1019 0.0881
Cytoplasmic Foci 0.0035 0.0095 0.007 0.0156 0.0039 0.0028 0.0035 0.0038 0.003 0.0038 0.005 0.0032 0.0026 0.0042 0.0021 0.001 0.0029 0.0053
Eisosomes 0.0001 0.0002 0.0002 0.0002 0.0002 0.0001 0.0008 0.0003 0.0003 0.0003 0.0004 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.8656 0.6858 0.7944 0.8172 0.8733 0.8482 0.8894 0.8421 0.8896 0.8874 0.8264 0.8713 0.8884 0.8244 0.9196 0.9501 0.8677 0.8601
Endosome 0.0086 0.0242 0.0152 0.0159 0.0154 0.0089 0.0065 0.013 0.0081 0.0077 0.0136 0.0099 0.0084 0.0195 0.0056 0.0071 0.0056 0.0091
Golgi 0.0018 0.0067 0.0081 0.0088 0.0073 0.0012 0.0024 0.007 0.004 0.0028 0.0048 0.0019 0.0024 0.0045 0.0021 0.0018 0.0027 0.0027
Lipid Particles 0.0089 0.0088 0.0065 0.0047 0.0026 0.0036 0.0096 0.0122 0.0088 0.0118 0.0095 0.0083 0.0064 0.0156 0.0083 0.0015 0.0052 0.0106
Mitochondria 0.0003 0.0042 0.0018 0.0009 0.0034 0.0007 0.0002 0.008 0.0007 0.0014 0.0039 0.0006 0.0004 0.0006 0.0003 0.0006 0.0002 0.0004
None 0.0087 0.0029 0.002 0.0036 0.0009 0.0026 0.0115 0.0054 0.0094 0.0075 0.007 0.008 0.0021 0.0023 0.0041 0.0002 0.0059 0.0041
Nuclear Periphery 0.0106 0.0141 0.0099 0.0091 0.0048 0.0072 0.0047 0.0069 0.0046 0.0056 0.0061 0.0056 0.0088 0.0074 0.004 0.0048 0.0031 0.0037
Nucleolus 0.0001 0.0001 0 0.0003 0 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0 0 0 0 0 0.0001
Nucleus 0.0018 0.0043 0.0014 0.0039 0.0016 0.0021 0.0006 0.0015 0.0007 0.0007 0.0011 0.001 0.0012 0.0006 0.0003 0.0005 0.0004 0.0009
Peroxisomes 0.0001 0.0002 0.0002 0.001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0 0 0 0.0001
Punctate Nuclear 0.0004 0.0008 0.0004 0.0009 0.0002 0.0005 0.0003 0.0006 0.0002 0.0002 0.0005 0.0003 0.0001 0.0003 0.0001 0.0001 0.0002 0.0011
Vacuole 0.0036 0.0078 0.0036 0.004 0.0034 0.0031 0.0029 0.0073 0.0033 0.0046 0.0029 0.0028 0.0021 0.0039 0.0021 0.002 0.0012 0.0028
Vacuole Periphery 0.0004 0.0008 0.0008 0.0005 0.0005 0.0004 0.0002 0.0006 0.0003 0.0004 0.0005 0.0003 0.0003 0.0005 0.0002 0.0004 0.0002 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 199.4132 184.4933 120.7959 140.759 209.5783 164.4753 182.1721 153.3324 165.0879 223.5581
Translational Efficiency 0.9533 0.923 0.8597 0.7472 0.788 1.1005 0.7661 0.6312 0.6693 0.6826

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
415 1429 1756 1565 2201 1673 370 1311 2616 3102 2126 2876

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 938.41 815.27 979.62 989.42 775.28 801.57 989.75 949.54 801.16 807.88 981.38 971.24
Standard Deviation 135.80 118.73 119.66 139.47 96.46 93.74 161.79 139.81 119.61 106.20 128.05 141.03
Intensity Change Log 2 — -0.202940 0.062004 0.076365 — 0.048111 0.352347 0.292511 — -0.083929 0.200628 0.178177

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004589 0.000914 0.000364 0.004886 0.000279 0.000976 0.003515 0.009670 0.000963 0.000947 0.000912 0.007067
Bud Neck 0.006042 0.006910 0.002762 0.012425 0.002445 0.009672 0.002321 0.012654 0.003015 0.008400 0.002685 0.012529
Bud Site 0.031962 0.007739 0.004665 0.029535 0.001851 0.006245 0.006342 0.032170 0.006628 0.006933 0.004957 0.030736
Cell Periphery 0.001886 0.000669 0.000347 0.000890 0.000868 0.000712 0.000704 0.002079 0.001029 0.000693 0.000409 0.001432
Cytoplasm 0.170609 0.297456 0.229828 0.234309 0.262398 0.254226 0.136148 0.218008 0.247837 0.274141 0.213524 0.226879
Cytoplasmic Foci 0.069813 0.166269 0.017414 0.044280 0.058365 0.131137 0.029365 0.056748 0.060181 0.147321 0.019494 0.049964
Eisosomes 0.000958 0.000718 0.000057 0.000403 0.000935 0.001301 0.000214 0.001590 0.000939 0.001032 0.000084 0.000944
Endoplasmic Reticulum 0.343579 0.231869 0.341208 0.240599 0.454791 0.306878 0.468782 0.368207 0.437149 0.272324 0.363410 0.298768
Endosome 0.022642 0.021441 0.010642 0.019562 0.006324 0.017770 0.014506 0.015222 0.008913 0.019461 0.011315 0.017584
Golgi 0.011522 0.022020 0.000414 0.003728 0.024003 0.032140 0.001895 0.006504 0.022023 0.027478 0.000672 0.004994
Lipid Particles 0.041922 0.092242 0.015548 0.038853 0.102805 0.113573 0.031472 0.053062 0.093147 0.103746 0.018319 0.045330
Mitochondria 0.001681 0.010273 0.000782 0.002507 0.010806 0.020357 0.000600 0.003610 0.009358 0.015711 0.000750 0.003010
Mitotic Spindle 0.006721 0.002910 0.001785 0.021014 0.000202 0.001291 0.001158 0.003265 0.001236 0.002037 0.001676 0.012923
None 0.000272 0.006185 0.001769 0.001329 0.007677 0.002522 0.001120 0.000854 0.006502 0.004209 0.001656 0.001112
Nuclear Periphery 0.008784 0.006343 0.102483 0.018784 0.004099 0.003581 0.043448 0.004486 0.004842 0.004853 0.092209 0.012267
Nuclear Periphery Foci 0.037427 0.009749 0.106829 0.051507 0.004897 0.003744 0.114614 0.042724 0.010057 0.006510 0.108184 0.047503
Nucleolus 0.000222 0.001163 0.000312 0.000594 0.000277 0.000706 0.000874 0.000304 0.000268 0.000916 0.000410 0.000462
Nucleus 0.040914 0.054187 0.116521 0.093639 0.040940 0.048655 0.074967 0.065604 0.040936 0.051203 0.109289 0.080860
Peroxisomes 0.002083 0.005768 0.000298 0.002831 0.004317 0.009438 0.001409 0.004018 0.003963 0.007748 0.000492 0.003372
Vacuole 0.194288 0.051795 0.045481 0.176046 0.010430 0.031888 0.066048 0.098075 0.039597 0.041058 0.049060 0.140503
Vacuole Periphery 0.002086 0.003379 0.000489 0.002279 0.001291 0.003188 0.000498 0.001144 0.001417 0.003276 0.000491 0.001762

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.22 3.68 0.12 -4.99 -5.77 -5.23 -2.31 -7.72 -7.11 -3.23 0.09 0.03 -8.38 -8.65 -8.15
Bud Neck -0.73 2.64 -5.48 -5.46 -10.28 -6.44 -0.30 -8.09 -1.95 -8.06 -7.11 0.02 -12.28 -4.74 -12.28
Bud Site 4.24 4.73 0.44 -8.21 -9.30 -4.89 -3.12 -10.40 -8.58 -7.78 -0.28 1.09 -11.33 -11.95 -12.42
Cell Periphery 2.17 2.76 1.86 -1.89 -6.57 1.81 1.17 -4.21 -4.86 -4.60 3.00 5.61 -2.19 -5.17 -7.30
Cytoplasm -9.94 -4.66 -4.80 7.38 -0.31 1.17 11.42 5.40 4.22 -6.89 -4.32 5.12 3.51 7.89 -1.83
Cytoplasmic Foci -14.10 9.80 4.44 24.52 -12.06 -16.68 6.84 0.17 15.74 -6.21 -24.59 17.70 3.58 28.64 -15.65
Eisosomes 0.62 2.88 1.80 3.57 -7.85 -3.12 7.78 -2.93 -1.14 -6.56 -1.00 10.74 0.20 1.12 -8.88
Endoplasmic Reticulum 3.62 -1.52 5.35 3.14 13.78 13.55 0.07 8.96 -3.05 5.30 17.69 7.93 17.95 0.83 10.15
Endosome -0.18 4.83 1.26 2.26 -6.70 -11.14 -6.98 -8.71 2.12 -0.01 -12.97 -4.53 -10.14 2.79 -6.16
Golgi -3.95 3.60 2.58 12.89 -4.20 -4.52 19.48 15.22 16.47 -5.40 -4.03 21.79 16.49 21.05 -8.45
Lipid Particles -9.73 5.68 0.92 15.13 -10.60 -2.26 15.72 12.44 14.12 -5.09 -2.93 25.69 15.66 21.10 -14.48
Mitochondria -7.70 1.42 -1.38 7.58 -5.74 -5.52 13.19 6.91 9.84 -3.70 -5.47 13.11 8.74 12.52 -5.46
Mitotic Spindle 1.60 2.10 -4.35 -6.84 -7.35 -2.40 -1.13 -5.40 -2.87 -2.19 -1.51 -0.87 -8.07 -7.41 -7.44
None -4.82 -3.56 -3.43 3.98 1.07 5.34 6.66 7.51 4.50 0.88 2.38 5.85 7.03 5.16 1.63
Nuclear Periphery 0.77 -22.44 -3.84 -6.10 21.09 0.83 -7.91 -0.52 -1.13 7.81 -0.21 -26.58 -7.02 -6.49 23.96
Nuclear Periphery Foci 6.83 -13.60 -2.71 -15.69 13.84 2.48 -14.00 -16.16 -16.79 8.73 4.09 -30.10 -19.94 -23.18 17.25
Nucleolus -5.44 -2.06 -5.86 2.60 -5.01 -3.43 -2.97 -1.16 2.76 2.67 -6.26 -3.40 -5.61 3.47 -1.44
Nucleus -2.73 -13.65 -10.30 -10.96 4.06 -3.29 -5.44 -8.33 -5.71 1.37 -5.24 -19.70 -15.99 -12.35 6.65
Peroxisomes -6.67 4.27 -0.92 6.96 -7.72 -9.20 7.25 0.87 8.60 -4.81 -9.84 15.23 2.41 11.42 -10.59
Vacuole 13.14 13.41 0.79 -26.08 -27.02 -12.35 -10.17 -21.97 -16.76 -5.18 1.63 -2.20 -25.96 -30.75 -26.53
Vacuole Periphery -2.11 2.44 -0.01 2.39 -3.11 -7.54 6.95 1.08 7.17 -2.98 -6.89 5.92 -0.44 5.06 -3.83
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein O-mannosyltransferase of the ER membrane; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues; 1 of 7 related proteins involved in O-glycosylation which is essential for cell wall rigidity; involved in ER quality control; amino terminus faces cytoplasm, carboxyl terminus faces ER lumen
Localization
Cell Percentages ER (95%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Pmt1

Pmt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pmt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available