Standard name
Human Ortholog
Description 2'-O-ribose methyltransferase; catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Cytoplasm 0.91 0.93 0.92 0.91 0.89 0.81 0.8 0.77 0.75 – 0.7 0.69 0.97 0.98 0.98 0.93 0.85 0.88 0.87 0.88 0.8 0.88 0.9 0.81
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.16 0.22 0.15 0.34 0.37 0.4 0.53 – 0.5 0.57 0 0 0 0 0 0 0 0 0.11 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.1 0.12 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 0 0 0 2 0 0 0 – 0 0 0 0 0 3 3 5 0 0 0 0 1 2
Bud 0 1 1 2 3 6 8 14 9 – 9 11 1 2 5 1 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 3 1 1 3 2 3 9 5 – 8 10 1 4 8 9 20 29 0 0 0 0 0 0
Cytoplasm 191 229 102 149 255 168 293 430 163 – 154 212 150 315 379 607 362 528 201 218 96 143 229 241
Endoplasmic Reticulum 7 7 3 1 6 5 1 2 0 – 2 1 3 1 1 28 16 27 9 3 4 5 8 21
Endosome 0 1 0 1 3 0 5 4 0 – 0 0 0 1 1 11 5 8 3 2 1 2 0 6
Golgi 1 1 0 0 0 0 0 0 0 – 0 0 0 0 0 1 5 2 2 3 0 0 0 3
Mitochondria 4 6 18 36 43 70 136 222 114 – 110 174 0 1 14 9 11 7 5 5 13 3 4 5
Nucleus 1 0 0 2 1 0 3 4 1 – 1 2 0 0 1 3 1 3 0 1 0 0 0 0
Nuclear Periphery 2 1 0 0 0 0 0 0 0 – 1 0 0 0 1 0 0 1 2 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 1 0 0 – 0 1 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 – 0 0 0 0 0 0 1 0 1 0 0 0 0 0
Vac/Vac Membrane 7 1 0 0 4 0 3 8 3 – 3 4 2 2 2 30 41 72 3 8 4 3 8 10
Unique Cell Count 209 245 111 163 285 208 368 555 216 219 307 155 320 386 651 425 603 230 250 121 163 256 298
Labelled Cell Count 216 251 125 193 318 253 454 694 295 288 415 157 326 412 702 465 683 230 250 121 163 256 298


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.7 7.3 4.8 5.6 5.6 5.0 4.7 4.6 4.1 – 3.9 3.7 8.3 7.8 6.8 9.8 10.9 12.0 7.7 8.0 8.6
Std Deviation (1e-4) 1.2 1.3 0.6 0.9 1.1 1.1 1.2 1.2 1.4 – 1.0 1.0 1.3 1.1 1.1 1.5 1.9 1.7 1.0 1.5 1.5
Intensity Change (Log2) – – – 0.21 0.21 0.05 -0.05 -0.09 -0.24 – -0.33 -0.41 0.79 0.68 0.49 1.02 1.17 1.3 0.67 0.72 0.83

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm -0.1 -0.7 -2.6 -3.0 -3.5 -3.6 – -4.4 -4.8 1.8 3.4 3.3 0.5 -1.8 -1.3
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 1.2 -0.3 3.3 0 0 0 – 0 0 -5.2 0 -4.8 0 -5.7 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 0 3.4 3.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0347 0.002 0.0056 0.002 0.0797 0.0035 0.0026 0.0009 0.0055 0.002 0.0091 0.0018 0 0.0075 0.0519 0.0037 0.0008 0.0095
Bud 0.001 0.0011 0.0013 0.0006 0.0014 0.0015 0.0021 0.0002 0.001 0.0011 0.0013 0.0002 0.0001 0.0016 0.0021 0.0007 0.0002 0.0006
Bud Neck 0.0097 0.0007 0.0008 0.0014 0.0012 0.0025 0.0006 0.0002 0.0004 0.0006 0.0005 0.0008 0.0001 0.0005 0.0005 0.0006 0.0004 0.0008
Bud Periphery 0.0014 0.0007 0.0012 0.0009 0.0028 0.0038 0.0024 0.0001 0.001 0.002 0.0016 0.0001 0 0.0006 0.0008 0.0005 0 0.0007
Bud Site 0.0094 0.0066 0.0038 0.0009 0.0026 0.0007 0.0022 0.0006 0.0015 0.0009 0.0033 0.0001 0 0.0082 0.0022 0.001 0.0002 0.0004
Cell Periphery 0.0028 0.0016 0.0014 0.0043 0.0018 0.0043 0.0002 0 0.0001 0.0003 0.0002 0 0 0.0003 0.0003 0.0002 0 0.0002
Cytoplasm 0.6535 0.9186 0.7691 0.8176 0.4932 0.7537 0.6971 0.9185 0.8282 0.8228 0.572 0.8423 0.7046 0.8507 0.8366 0.6756 0.8352 0.7127
Cytoplasmic Foci 0.0395 0.0173 0.0379 0.0135 0.0395 0.0339 0.0503 0.0264 0.0325 0.0269 0.0538 0.039 0.075 0.0716 0.0259 0.0508 0.0528 0.0407
Eisosomes 0.0008 0 0.0001 0.0002 0.0004 0.0001 0.0001 0 0 0.0001 0.0002 0 0 0 0.0003 0 0 0.0001
Endoplasmic Reticulum 0.0625 0.0067 0.028 0.0288 0.0087 0.0312 0.0304 0.0045 0.0072 0.0032 0.0047 0.0074 0.0039 0.0079 0.0068 0.005 0.0049 0.0061
Endosome 0.0537 0.0265 0.078 0.0569 0.1589 0.0916 0.125 0.0318 0.0936 0.0667 0.1665 0.0743 0.2015 0.017 0.0373 0.1143 0.0968 0.0854
Golgi 0.0253 0.0056 0.0159 0.0057 0.0231 0.0219 0.0155 0.0052 0.0088 0.0071 0.0373 0.0154 0.0047 0.0113 0.0168 0.0335 0.0025 0.022
Lipid Particles 0.0158 0.0004 0.0014 0.0053 0.0399 0.0014 0.0096 0.0004 0.0005 0.0041 0.0319 0.0014 0.0001 0.0017 0.0009 0.0012 0.0002 0.0003
Mitochondria 0.0068 0.0018 0.0116 0.0069 0.0575 0.0201 0.0055 0.0004 0.0034 0.0369 0.0683 0.0093 0.0004 0.0011 0.0044 0.0359 0.0003 0.0127
None 0.0311 0.0021 0.0281 0.022 0.0228 0.0042 0.0165 0.0015 0.0029 0.0014 0.0019 0.0012 0.0031 0.0014 0.0058 0.0666 0.0014 0.1006
Nuclear Periphery 0.0126 0.0006 0.0024 0.0074 0.0079 0.002 0.0088 0.0005 0.0023 0.0021 0.0046 0.0008 0.0004 0.0013 0.0009 0.0011 0.0004 0.0006
Nucleolus 0.0024 0 0.0001 0.0023 0.005 0.0008 0.0014 0 0 0.0002 0.0007 0 0 0 0 0.0001 0 0
Nucleus 0.0056 0.0008 0.0014 0.0061 0.0025 0.0048 0.0074 0.0006 0.0011 0.0015 0.0018 0.0007 0.0002 0.0008 0.0007 0.001 0.0004 0.0006
Peroxisomes 0.0067 0.0002 0.0004 0.0012 0.0035 0.0036 0.0049 0.0031 0.0005 0.0007 0.0173 0.0007 0.0001 0.0129 0.0004 0.001 0.0002 0.0006
Punctate Nuclear 0.0044 0.0001 0.0006 0.0044 0.0007 0.0038 0.0031 0.0029 0.0003 0.0002 0.0099 0.0003 0.0001 0.0015 0.0003 0.0003 0.0002 0.0005
Vacuole 0.0148 0.0057 0.0081 0.0086 0.0364 0.0068 0.0106 0.0018 0.0067 0.013 0.0086 0.0025 0.004 0.0016 0.0041 0.0047 0.0025 0.0035
Vacuole Periphery 0.0053 0.0008 0.0028 0.0031 0.0105 0.0037 0.0039 0.0005 0.0023 0.0062 0.0047 0.0015 0.0017 0.0006 0.0009 0.0023 0.0007 0.0017

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 50.0384 40.956 38.5407 38.0106 38.1629 31.2087 34.4703 33.8827 24.8182 45.014
Translational Efficiency 0.6298 0.7389 0.6685 0.5751 0.6499 0.6111 0.6477 0.4316 0.5484 0.4669

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1213 653 2343 1106 911 1777 241 2481 2124 2430 2584 3587

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 651.86 1068.32 1103.57 1097.35 870.48 945.89 1173.36 1101.83 745.63 978.79 1110.08 1100.45
Standard Deviation 93.02 143.98 180.89 137.44 110.39 128.71 143.85 149.75 147.90 143.64 178.92 146.08
Intensity Change Log 2 — 0.712710 0.759544 0.751390 — 0.119861 0.430763 0.340019 — 0.403923 0.580799 0.530675

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000218 0.001204 0.000330 0.001363 0.000293 0.000454 0.000536 0.000959 0.000250 0.000655 0.000349 0.001083
Bud Neck 0.016775 0.002700 0.002133 0.002625 0.003686 0.004462 0.003559 0.003484 0.011161 0.003989 0.002266 0.003219
Bud Site 0.024937 0.044105 0.013489 0.028770 0.020894 0.027051 0.022599 0.034418 0.023203 0.031634 0.014339 0.032676
Cell Periphery 0.000462 0.000188 0.000065 0.000077 0.000156 0.000114 0.000096 0.000065 0.000331 0.000134 0.000068 0.000069
Cytoplasm 0.449542 0.535983 0.774460 0.552609 0.586889 0.453045 0.588630 0.690588 0.508451 0.475333 0.757129 0.648044
Cytoplasmic Foci 0.323719 0.279096 0.054184 0.112370 0.269655 0.236747 0.135093 0.125939 0.300531 0.248127 0.061730 0.121755
Eisosomes 0.000291 0.000031 0.000005 0.000015 0.000050 0.000033 0.000022 0.000013 0.000187 0.000033 0.000007 0.000014
Endoplasmic Reticulum 0.003383 0.002273 0.001019 0.001546 0.003590 0.002655 0.000890 0.000368 0.003472 0.002552 0.001007 0.000731
Endosome 0.028377 0.029120 0.004105 0.020673 0.022197 0.052145 0.015351 0.020985 0.025726 0.045958 0.005154 0.020889
Golgi 0.021580 0.022227 0.002073 0.010612 0.018542 0.022018 0.000970 0.013275 0.020277 0.022074 0.001970 0.012454
Lipid Particles 0.008807 0.002010 0.001387 0.001618 0.002811 0.002676 0.003341 0.002546 0.006235 0.002497 0.001569 0.002260
Mitochondria 0.027937 0.002968 0.000540 0.004039 0.004245 0.004646 0.000464 0.001593 0.017776 0.004195 0.000533 0.002347
Mitotic Spindle 0.000256 0.003948 0.029918 0.039500 0.002071 0.010670 0.017585 0.012586 0.001034 0.008864 0.028768 0.020885
None 0.003784 0.000216 0.002276 0.000465 0.000923 0.000408 0.000634 0.000182 0.002557 0.000356 0.002123 0.000269
Nuclear Periphery 0.000150 0.000040 0.000518 0.000318 0.000045 0.000117 0.000422 0.000088 0.000105 0.000096 0.000509 0.000159
Nuclear Periphery Foci 0.000434 0.000387 0.003541 0.001536 0.000502 0.000367 0.008817 0.000676 0.000463 0.000373 0.004033 0.000941
Nucleolus 0.000774 0.000079 0.000343 0.000281 0.000168 0.000521 0.000162 0.000177 0.000514 0.000402 0.000326 0.000209
Nucleus 0.021024 0.002427 0.069847 0.009864 0.006182 0.005439 0.019342 0.004899 0.014658 0.004629 0.065137 0.006430
Peroxisomes 0.003230 0.002293 0.000584 0.003514 0.002129 0.002472 0.001833 0.005998 0.002758 0.002424 0.000701 0.005232
Vacuole 0.049906 0.055842 0.037731 0.203393 0.048237 0.154696 0.179258 0.077047 0.049190 0.128131 0.050931 0.116004
Vacuole Periphery 0.014414 0.012865 0.001451 0.004812 0.006732 0.019262 0.000396 0.004114 0.011119 0.017543 0.001352 0.004329

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.54 -3.69 -2.70 0.57 -1.95 -0.90 -2.72 -4.19 -1.89 -2.49 -1.89 -3.51 -5.24 -0.79 -3.91
Bud Neck 13.01 13.24 13.47 0.98 0.87 -1.47 0.71 0.73 3.10 -0.27 10.45 12.78 12.25 3.42 -1.93
Bud Site -4.98 4.95 1.99 6.72 -3.18 -3.20 1.01 -5.43 -1.80 -4.39 -4.41 5.61 -2.40 2.52 -8.75
Cell Periphery 6.34 10.34 10.65 5.45 1.16 2.11 4.77 10.34 2.95 4.99 7.55 11.31 12.29 5.01 1.84
Cytoplasm -6.28 -34.74 -8.65 -0.83 19.55 11.43 2.45 -9.57 -25.20 -8.12 3.89 -28.91 -18.08 -21.24 11.66
Cytoplasmic Foci 4.44 44.38 35.54 20.63 -7.13 3.90 15.03 19.95 20.10 -0.83 8.56 48.97 37.93 28.03 -14.13
Eisosomes 14.01 15.48 15.13 5.42 -6.55 3.38 4.94 8.12 10.30 6.31 14.00 16.31 15.95 11.63 -5.75
Endoplasmic Reticulum 1.81 4.90 4.18 2.37 0.62 1.21 4.16 4.99 5.28 4.47 1.83 6.05 7.44 5.65 3.42
Endosome -0.23 16.63 8.68 6.43 -7.10 -12.81 5.49 2.44 16.30 -4.13 -11.06 19.83 7.52 17.54 -14.97
Golgi -0.25 16.94 9.46 8.16 -2.47 -1.94 15.37 5.61 7.41 -12.73 -1.27 22.01 10.61 10.44 -10.38
Lipid Particles 11.38 13.06 13.16 1.55 1.21 0.33 -0.38 0.97 0.41 1.01 9.27 12.94 11.51 1.02 -2.40
Mitochondria 9.76 12.37 11.10 0.68 -1.87 -0.26 3.01 2.18 4.00 -3.13 8.72 12.26 11.28 3.66 -3.20
Mitotic Spindle -2.62 -13.27 -6.96 -5.47 1.49 -4.68 -3.18 -6.13 -0.55 0.55 -5.89 -13.17 -9.87 -3.53 5.19
None 4.46 2.01 4.13 -3.68 13.76 1.87 0.30 2.71 2.54 4.03 4.64 1.07 4.81 1.07 17.24
Nuclear Periphery 5.06 -11.03 -4.28 -6.91 4.98 -4.69 -7.28 -3.04 0.50 6.34 0.51 -13.51 -3.58 -4.11 10.92
Nuclear Periphery Foci 0.17 -7.51 -3.72 -7.32 5.90 1.25 -4.85 -1.36 -2.01 4.67 0.54 -9.13 -2.71 -4.44 8.15
Nucleolus 2.45 1.26 1.83 -6.58 3.97 -1.59 -0.70 -0.89 1.47 0.13 0.45 0.72 1.83 1.17 5.90
Nucleus 10.23 -21.20 2.40 -15.19 27.88 1.08 -7.15 -1.59 -3.64 6.91 9.08 -27.22 4.16 -11.89 32.90
Peroxisomes 2.62 14.21 3.45 0.31 -6.03 -0.38 1.08 -3.44 -6.95 -8.85 0.86 5.65 -3.40 -6.20 -13.43
Vacuole -1.72 -1.62 -27.93 -24.76 -27.75 -19.29 -13.29 -14.02 10.16 10.13 -18.46 -7.75 -27.65 -4.56 -18.46
Vacuole Periphery 0.80 12.28 9.98 5.56 -1.93 -9.14 9.09 4.21 12.93 -8.23 -5.33 14.17 10.76 14.02 -5.29
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description 2'-O-ribose methyltransferase; catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs
Localization
Cell Percentages cytoplasm (86%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Trm3

Trm3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Trm3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available