Standard name
Human Ortholog
Description Sorting nexin family member; required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.05 0 0 0 0 0.09 0 0 0.05 0 0.06 0 0 0.09 0.05 0.07 0 0 0 0 0 0
Bud 0 0 0 0 0 0.06 0 0.06 0.1 0.1 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.21 0.27 0.35 0.17 0.18 0.21 0.24 0.24 0.23 0.22 0.21 0.18 0.22 0.36 0.48 0.17 0.2 0.18 0.09 0.06 0.08 0.09 0.08 0.12
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.58 0.6 0.43 0.34 0.4 0.4 0.34 0.25 0.23 0.23 0.19 0.25 0.57 0.51 0.44 0.45 0.42 0.53 0.7 0.7 0.54 0.62 0.59 0.6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0
Mitochondria 0.13 0 0 0.07 0 0.17 0.12 0.15 0.44 0.32 0.5 0.36 0 0 0 0.08 0 0 0.06 0 0.15 0.08 0.08 0.06
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.08 0 0 0 0.07 0.05 0.07 0.08 0.06 0 0 0 0.05 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0
SpindlePole 0.17 0.13 0.17 0.46 0.43 0.25 0.36 0.35 0.14 0.27 0.12 0.29 0.22 0.22 0.18 0.29 0.32 0.3 0 0 0 0.08 0.05 0.09
Vac/Vac Membrane 0.07 0.1 0.1 0.05 0.07 0 0 0 0.05 0 0 0 0.1 0.05 0.05 0.17 0.17 0.11 0 0.06 0.09 0.08 0.13 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 8 5 6 5 1 8 15 3 7 7 5 6 5 0 20 9 18 6 5 3 0 1 2
Bud 7 2 2 1 2 7 9 11 13 19 8 10 2 0 1 2 0 3 1 1 1 0 0 1
Bud Neck 0 0 0 2 0 0 0 1 1 0 2 0 1 0 0 0 0 0 2 1 2 1 2 1
Bud Site 0 0 0 0 0 0 3 0 0 0 1 3 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 1 0 1 2 0 1 0 0 1 2 2 1 0 0 0 0 0 0
Cytoplasm 58 50 39 25 30 26 48 43 30 40 31 30 23 49 79 36 36 46 27 13 12 11 13 19
Endoplasmic Reticulum 6 9 2 1 2 5 4 3 2 1 1 0 3 3 1 6 8 5 5 2 2 0 2 2
Endosome 157 109 48 49 66 51 68 44 30 42 28 42 60 69 71 95 75 135 223 157 86 78 100 95
Golgi 0 5 0 1 2 0 1 0 0 0 0 0 0 0 1 13 10 7 2 6 1 0 1 0
Mitochondria 35 2 1 10 3 21 25 27 58 59 73 61 0 0 0 17 8 11 20 5 24 10 13 9
Nucleus 0 1 1 0 1 1 2 4 1 0 4 2 1 0 0 2 2 0 0 1 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 2 3 0 12 6 5 9 13 6 13 12 10 0 1 4 11 7 10 0 0 0 0 0 0
Peroxisomes 7 2 1 5 7 5 9 2 3 3 4 5 2 3 9 1 1 6 0 1 0 0 0 0
SpindlePole 45 24 19 67 70 31 72 62 18 49 18 50 23 30 30 61 57 76 13 8 6 10 8 13
Vac/Vac Membrane 19 18 11 8 11 3 9 4 6 8 2 6 11 7 8 35 31 28 12 14 14 9 21 9
Unique Cell Count 272 183 111 146 164 126 201 176 132 182 147 171 105 135 163 212 180 257 319 224 162 127 171 158
Labelled Cell Count 343 233 129 187 205 156 269 229 172 243 191 225 132 167 205 301 246 347 319 224 162 127 171 158


Endosome

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.5 7.4 7.1 6.6 7.7 6.6 6.6 7.0 5.6 6.1 5.7 6.1 7.4 7.5 7.6 10.5 11.8 9.8 6.6 6.9 7.3
Std Deviation (1e-4) 0.7 0.9 1.6 1.6 1.8 1.7 1.4 1.5 1.2 1.2 1.2 1.6 1.2 1.1 1.3 2.1 3.4 2.4 1.5 1.2 1.4
Intensity Change (Log2) – – – -0.11 0.11 -0.11 -0.11 -0.03 -0.36 -0.22 -0.32 -0.22 0.06 0.07 0.1 0.56 0.72 0.46 -0.11 -0.04 0.04


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 1.3 0 0 0.1 0 0.4 0 0 1.6 0.2 0.9
Bud 0 0 0 0 1.8 2.6 2.8 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -3.3 -3.2 -2.5 -2.1 -2.0 -2.1 -2.5 -2.5 -3.4 -2.1 0.2 2.2 -3.7 -2.9 -3.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -1.6 -0.5 -0.4 -1.6 -3.2 -3.4 -3.6 -4.2 -3.3 2.0 1.2 0.1 0.3 -0.3 1.6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.2 3.5 4.0 7.8 6.5 8.6 6.9 0 0 0 2.6 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 3.1 0 0 0 2.9 0 0 3.1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 4.8 4.4 1.4 3.5 3.3 -0.8 1.9 -1.1 2.3 0.9 1.0 0.3 2.3 2.7 2.5
Vacuole -1.3 -1.0 -2.5 -1.9 -2.8 -1.6 -1.9 -3.1 -2.2 0.1 -1.4 -1.6 1.6 1.7 0.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2617 0.9006 0.8532 0.5274 0.3132 0.864 1.2562 1.509 1.395 1.2742 1.0872 1.5482 1.3483 1.6877 1.2594 1.3175 2.0967 1.387
Actin 0.021 0.0034 0.004 0.0001 0.0008 0.0021 0.0032 0.001 0.0016 0.0036 0.0146 0.0038 0.0284 0.0002 0.022 0 0.0683 0.029
Bud 0.0006 0.0029 0.0043 0.0002 0.0001 0.0007 0.0003 0.0009 0.0021 0.0005 0.0006 0.0003 0.0035 0.0006 0.0017 0.0002 0.0026 0.0003
Bud Neck 0.0011 0.001 0.0006 0.0002 0.0004 0.001 0.0007 0.0005 0.0011 0.0019 0.0005 0.0022 0.0021 0.0004 0.0011 0.0003 0.0106 0.001
Bud Periphery 0.0006 0.0013 0.0021 0.0001 0.0001 0.0007 0.0003 0.0009 0.0032 0.0008 0.0007 0.0004 0.0022 0.0003 0.0017 0.0001 0.0035 0.0004
Bud Site 0.0049 0.0242 0.0028 0.0004 0.0004 0.0005 0.0028 0.0053 0.0047 0.0006 0.0009 0.0007 0.0142 0.0025 0.0087 0.0002 0.0408 0.0007
Cell Periphery 0.0003 0.0005 0.0002 0 0 0.0001 0.0002 0.0002 0.0004 0.0001 0.0001 0.0001 0.0011 0.0001 0.0002 0 0.0011 0.0001
Cytoplasm 0.1258 0.2878 0.1846 0.1636 0.1081 0.2274 0.1196 0.1029 0.1626 0.1503 0.051 0.1411 0.1529 0.3051 0.1835 0.1538 0.0524 0.2009
Cytoplasmic Foci 0.258 0.2429 0.2618 0.2235 0.224 0.3097 0.2317 0.3364 0.2671 0.228 0.2254 0.2968 0.2109 0.2619 0.2563 0.1782 0.1998 0.3382
Eisosomes 0.0003 0.0001 0.0002 0 0.0001 0 0.0002 0 0.0001 0.0001 0.0001 0.0001 0.0003 0 0.0001 0 0.0004 0.0002
Endoplasmic Reticulum 0.0071 0.0046 0.0034 0.0036 0.002 0.0032 0.0045 0.0025 0.0029 0.0041 0.0022 0.0029 0.0132 0.0043 0.0037 0.0028 0.0041 0.0042
Endosome 0.2982 0.2854 0.3413 0.3186 0.4566 0.3079 0.4303 0.4289 0.3683 0.4372 0.5393 0.4189 0.3632 0.3269 0.3785 0.5635 0.409 0.2981
Golgi 0.0252 0.011 0.0168 0.0074 0.0321 0.0173 0.0361 0.0294 0.0265 0.0282 0.0573 0.0348 0.0265 0.015 0.0367 0.0164 0.0765 0.0256
Lipid Particles 0.0493 0.0137 0.0295 0.0522 0.0367 0.0327 0.0465 0.0243 0.0408 0.0056 0.0133 0.0216 0.0558 0.0176 0.0183 0.0059 0.0422 0.0337
Mitochondria 0.0138 0.0058 0.0044 0.0017 0.0311 0.0026 0.0084 0.0024 0.0208 0.0467 0.0138 0.0151 0.0064 0.0018 0.0052 0.0007 0.0176 0.0112
None 0.0764 0.0801 0.0858 0.1792 0.0776 0.0586 0.0653 0.0238 0.0532 0.0201 0.0127 0.0212 0.0412 0.0248 0.0355 0.0318 0.0088 0.025
Nuclear Periphery 0.021 0.0014 0.0027 0.0026 0.0012 0.0007 0.0092 0.0008 0.0008 0.0025 0.001 0.0007 0.0107 0.001 0.0011 0.0013 0.0088 0.0026
Nucleolus 0.0019 0.0021 0.0038 0.0005 0.0002 0.0002 0.0005 0.0003 0.0005 0.0002 0.0002 0.0001 0.0077 0.0002 0.0002 0.0001 0.0075 0.0004
Nucleus 0.0081 0.0024 0.0084 0.0013 0.0006 0.0008 0.0024 0.0005 0.0008 0.0015 0.0005 0.0004 0.0096 0.0008 0.0005 0.0007 0.0029 0.0006
Peroxisomes 0.0307 0.0062 0.0176 0.0156 0.0143 0.0204 0.0192 0.0244 0.0237 0.0418 0.0523 0.0279 0.0196 0.0126 0.0292 0.0016 0.0208 0.0153
Punctate Nuclear 0.0181 0.0025 0.0076 0.0028 0.0028 0.0046 0.0024 0.0016 0.0014 0.0008 0.0007 0.0012 0.0083 0.0023 0.0019 0.0007 0.0061 0.0056
Vacuole 0.0272 0.0194 0.0157 0.0223 0.0077 0.0071 0.0138 0.011 0.0146 0.0201 0.0095 0.0077 0.0189 0.0191 0.0112 0.036 0.0133 0.0052
Vacuole Periphery 0.0104 0.0014 0.0027 0.0039 0.0031 0.0015 0.0023 0.0019 0.0028 0.0053 0.0033 0.002 0.0033 0.0024 0.0028 0.0057 0.003 0.0018

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.3283 11.2846 11.038 13.1969 11.9032 10.3226 11.7988 13.6516 14.7088 12.5684
Translational Efficiency 0.8102 0.871 0.8504 0.8352 0.7337 1.0108 0.9151 0.8435 0.8463 0.7834

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1923 1139 101 939 758 2232 210 76 2681 3371 311 1015

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 704.49 664.89 1171.53 981.71 823.75 809.07 1040.26 1109.47 738.21 760.35 1082.89 991.28
Standard Deviation 85.63 107.71 145.38 139.00 94.94 109.33 131.08 158.91 103.40 128.39 149.15 144.55
Intensity Change Log 2 — -0.083464 0.733743 0.478718 — -0.025942 0.336666 0.429592 — -0.052174 0.533343 0.452446

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002802 0.000325 0.016022 0.000765 0.000420 0.000455 0.000361 0.003118 0.002129 0.000411 0.005447 0.000941
Bud Neck 0.033078 0.018362 0.012146 0.012927 0.015759 0.011420 0.017099 0.005521 0.028182 0.013766 0.015490 0.012372
Bud Site 0.023045 0.016634 0.029708 0.044842 0.010302 0.015534 0.013112 0.060195 0.019442 0.015906 0.018502 0.045992
Cell Periphery 0.000243 0.000114 0.000118 0.000053 0.000131 0.000058 0.000106 0.000072 0.000211 0.000077 0.000110 0.000054
Cytoplasm 0.089682 0.115619* 0.004062 0.074949 0.061677 0.041009 0.028325 0.138041* 0.081764 0.066218 0.020445 0.079673
Cytoplasmic Foci 0.344452* 0.302093* 0.276472* 0.183779* 0.240125* 0.257787* 0.121748 0.279779* 0.314956* 0.272757* 0.171996 0.190967*
Eisosomes 0.000875 0.000097 0.000052 0.000024 0.000123 0.000060 0.000099 0.000024 0.000662 0.000073 0.000083 0.000024
Endoplasmic Reticulum 0.001194 0.001147 0.001436 0.000648 0.001525 0.000452 0.001169 0.000123 0.001288 0.000687 0.001256 0.000608
Endosome 0.209244* 0.311475* 0.327472* 0.312746* 0.491294* 0.468736* 0.439127* 0.243067* 0.288988* 0.415601* 0.402866* 0.307529*
Golgi 0.157862* 0.042791 0.049672 0.012422 0.043087 0.064210 0.004640 0.004356 0.125412* 0.056973 0.019265 0.011818
Lipid Particles 0.031666 0.021048 0.017047 0.005126 0.026479 0.012514 0.014288 0.007488 0.030199 0.015397 0.015184 0.005303
Mitochondria 0.032099 0.017290 0.000701 0.002107 0.006066 0.016483 0.000590 0.000027 0.024739 0.016755 0.000626 0.001952
Mitotic Spindle 0.001824 0.006807 0.081087 0.090965 0.003343 0.020984 0.043072 0.049158 0.002254 0.016194 0.055418 0.087835
None 0.000690 0.003247 0.000019 0.000100 0.000297 0.000405 0.000293 0.000030 0.000579 0.001365 0.000204 0.000095
Nuclear Periphery 0.000049 0.000449 0.000707 0.000514 0.000298 0.000149 0.000975 0.000101 0.000119 0.000250 0.000888 0.000483
Nuclear Periphery Foci 0.000800 0.003619 0.020016 0.005292 0.001732 0.001208 0.031659 0.001989 0.001064 0.002023 0.027878 0.005044
Nucleolus 0.000676 0.003621 0.001399 0.000798 0.000392 0.000669 0.010565 0.000118 0.000596 0.001666 0.007589 0.000747
Nucleus 0.003523 0.013632 0.001234 0.002401 0.002737 0.001238 0.031623 0.001038 0.003301 0.005426 0.021754 0.002299
Peroxisomes 0.045058 0.019313 0.061785 0.029230 0.022675 0.021325 0.044051 0.071816 0.038729 0.020645 0.049810 0.032419
Vacuole 0.016582 0.090441 0.092368 0.213869* 0.064743 0.056674 0.193963 0.133424 0.030199 0.068083 0.160969 0.207846*
Vacuole Periphery 0.004558 0.011876 0.006476 0.006443 0.006794 0.008629 0.003134 0.000516 0.005190 0.009726 0.004219 0.005999

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 5.20 -1.39 4.15 -2.05 1.62 -0.34 0.18 -1.43 -1.41 -1.44 4.97 -1.06 3.21 -2.09 1.49
Bud Neck 5.56 5.86 8.17 2.73 -0.26 2.17 -0.24 5.37 5.61 4.02 7.98 5.00 8.04 1.06 1.18
Bud Site 3.25 -1.49 -5.82 -7.92 -2.03 -3.16 -1.80 -3.72 -3.29 -3.38 2.35 -0.10 -7.61 -8.85 -6.59
Cell Periphery 4.43 3.74 6.89 6.04 4.22 4.22 0.90 2.68 -0.64 1.83 6.46 4.14 7.65 3.63 4.84
Cytoplasm -4.23 22.33 -1.09 2.62 -16.03 3.61 3.56 -3.92 -4.66 -4.82 3.58 11.39 -3.27 -5.63 -11.18
Cytoplasmic Foci 5.42 3.64 22.96 15.15 4.39 -2.04 10.46 -0.41 0.34 -5.63 8.01 13.72 19.77 14.23 -0.98
Eisosomes 7.73 8.14 8.48 8.87 3.27 4.10 0.95 6.78 4.88 5.18 8.13 7.86 8.82 8.78 5.92
Endoplasmic Reticulum 0.13 -0.66 1.52 3.06 1.65 3.28 0.13 4.31 4.28 4.82 2.01 -0.63 2.40 1.14 3.30
Endosome -10.91 -5.43 -5.43 3.92 2.59 1.81 3.56 11.11 10.90 6.47 -17.05 -4.94 3.19 16.30 6.35
Golgi 23.67* 11.99 33.65* 11.41 4.54 -5.14 11.25 11.58 24.55 0.99 18.38 24.18 32.88 21.88 2.80
Lipid Particles 4.17 3.30 13.46 8.36 3.17 4.52 2.52 5.48 2.47 1.54 8.30 4.48 14.63 9.00 3.21
Mitochondria 6.26 17.46 16.03 8.59 -1.26 -5.58 3.97 4.41 12.96 2.50 4.86 17.84 15.54 12.57 -1.41
Mitotic Spindle -4.68 -3.99 -13.22 -12.38 -0.71 -8.70 -4.03 -2.58 -1.65 -0.33 -11.40 -5.74 -13.40 -11.19 -3.07
None -2.85 4.72 3.99 3.50 -4.22 -0.49 -0.94 1.34 1.71 1.75 -2.33 0.66 4.11 3.82 1.48
Nuclear Periphery -4.95 -3.56 -5.95 -1.25 0.70 1.11 -3.85 0.98 -0.45 5.09 -2.87 -6.04 -4.83 -3.47 2.89
Nuclear Periphery Foci -2.96 -2.47 -4.56 -1.68 1.75 1.36 -4.16 -1.26 -2.11 4.03 -2.11 -4.85 -4.51 -3.56 4.02
Nucleolus -4.27 -0.65 -1.25 3.90 0.29 -2.33 -3.15 2.87 4.20 3.20 -3.81 -3.14 -1.67 2.69 3.02
Nucleus -5.53 1.28 0.18 5.83 -1.27 2.59 -3.99 0.74 -1.02 4.07 -2.71 -3.78 0.08 2.93 3.79
Peroxisomes 10.43 -1.53 6.80 -2.67 3.34 0.52 -3.17 -3.03 -3.16 -1.23 9.88 -1.74 4.13 -3.35 3.60
Vacuole -18.10 -6.05 -25.82 -16.08 -8.24 1.60 -7.90 -4.79 -5.10 0.49 -15.16 -10.89 -24.83 -20.04 -4.15
Vacuole Periphery -8.34 -1.33 -0.92 5.88 0.71 -2.42 5.09 10.22 18.26 5.64 -9.40 1.98 0.38 6.03 -1.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Sorting nexin family member; required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate
Localization
Cell Percentages endosome (39%), cytoplasm (14%), mixed (26%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Atg20

Atg20


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Atg20-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available