| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Mitochondrial glycine transporter; required for the transport of glycine into mitochondria for initiation of heme biosynthesis, with YMC1 acting as a secondary transporter; homolog of human SLC25A38, a mitochondrial glycine transporter associated with nonsyndromic autosomal recessive congenital sideroblastic anemia; human SLC25A38 can complement the heme deficiency associated with the null mutant; GFP-fusion protein is induced in response to the DNA-damaging agent MMS |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 5 | 1 | – | – | – | 3 | 7 | 2 | 4 | 3 | 5 |
| Bud | 2 | 4 | 15 | 4 | 13 | 7 | 29 | 23 | 20 | 15 | 15 | 18 | 1 | 2 | 1 | – | – | – | 0 | 1 | 0 | 1 | 1 | 2 |
| Bud Neck | 0 | 0 | 1 | 0 | 1 | 1 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | – | – | – | 0 | 4 | 0 | 4 | 3 | 6 |
| Bud Site | 0 | 0 | 2 | 1 | 2 | 2 | 11 | 2 | 12 | 7 | 3 | 5 | 0 | 0 | 1 | – | – | – | – | – | – | – | – | – |
| Cell Periphery | 0 | 4 | 4 | 2 | 2 | 2 | 1 | 0 | 3 | 2 | 2 | 1 | 0 | 3 | 3 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 4 | 43 | 17 | 26 | 46 | 27 | 72 | 65 | 58 | 58 | 40 | 66 | 23 | 62 | 79 | – | – | – | 0 | 9 | 1 | 1 | 1 | 3 |
| Endoplasmic Reticulum | 0 | 13 | 5 | 0 | 0 | 4 | 0 | 0 | 2 | 1 | 1 | 3 | 6 | 3 | 7 | – | – | – | 0 | 3 | 0 | 1 | 5 | 2 |
| Endosome | 2 | 5 | 2 | 12 | 12 | 1 | 1 | 5 | 2 | 0 | 0 | 3 | 3 | 6 | 17 | – | – | – | 6 | 24 | 19 | 17 | 15 | 16 |
| Golgi | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | – | – | – | 3 | 3 | 3 | 3 | 4 | 4 |
| Mitochondria | 55 | 164 | 198 | 160 | 191 | 225 | 339 | 324 | 379 | 328 | 231 | 326 | 6 | 11 | 7 | – | – | – | 61 | 215 | 177 | 102 | 95 | 119 |
| Nucleus | 1 | 1 | 0 | 1 | 1 | 6 | 12 | 9 | 13 | 9 | 3 | 4 | 2 | 3 | 1 | – | – | – | 0 | 1 | 0 | 1 | 1 | 0 |
| Nuclear Periphery | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 3 | 1 | 0 | 0 | 0 | – | – | – | 0 | 2 | 0 | 0 | 1 | 1 |
| Nucleolus | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4 | 3 | 2 | 1 | 3 | 0 | 0 | 0 | – | – | – | 0 | 1 | 0 | 0 | 1 | 0 |
| Peroxisomes | 0 | 2 | 9 | 7 | 9 | 2 | 4 | 1 | 4 | 0 | 0 | 3 | 0 | 0 | 1 | – | – | – | 3 | 4 | 9 | 5 | 7 | 7 |
| SpindlePole | 0 | 1 | 11 | 10 | 16 | 5 | 30 | 20 | 15 | 34 | 8 | 20 | 2 | 3 | 4 | – | – | – | 0 | 5 | 2 | 1 | 3 | 0 |
| Vac/Vac Membrane | 6 | 31 | 8 | 4 | 12 | 12 | 12 | 6 | 17 | 12 | 7 | 6 | 4 | 12 | 7 | – | – | – | 3 | 22 | 5 | 12 | 20 | 18 |
| Unique Cell Count | 60 | 229 | 225 | 189 | 246 | 252 | 402 | 377 | 424 | 377 | 260 | 359 | 50 | 104 | 120 | 88 | 310 | 230 | 161 | 174 | 194 | |||
| Labelled Cell Count | 70 | 272 | 273 | 227 | 307 | 297 | 514 | 460 | 529 | 471 | 316 | 459 | 56 | 110 | 129 | 88 | 310 | 230 | 161 | 174 | 194 | |||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 5.0 | 4.4 | 3.7 | 4.0 | 3.9 | 3.6 | 3.1 | 3.2 | 2.9 | 3.0 | 2.8 | 2.8 | 5.6 | 5.4 | 5.4 | – | – | – | 5.9 | 6.6 | 6.3 |
| Std Deviation (1e-4) | 2.0 | 0.8 | 0.9 | 1.6 | 1.4 | 1.7 | 1.5 | 1.4 | 1.0 | 1.2 | 0.9 | 0.9 | 0.8 | 1.1 | 1.4 | – | – | – | 1.4 | 1.6 | 1.3 |
| Intensity Change (Log2) | – | – | – | 0.12 | 0.09 | -0.03 | -0.28 | -0.21 | -0.35 | -0.32 | -0.39 | -0.4 | 0.6 | 0.54 | 0.55 | – | – | – | 0.68 | 0.84 | 0.77 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasmic Foci | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Eisosomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Lipid Particles | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| None | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Punctate Nuclear | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 3.5825 | 3.2025 | 3.1685 | 16.0927 | 8.5155 | 5.9675 | 5.3968 | 5.8279 | 12.1685 | 11.1738 |
| Translational Efficiency | 1.7538 | 2.0158 | 2.652 | 1.0102 | 1.3111 | 1.6572 | 1.5885 | 1.6582 | 1.3615 | 1.2094 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | – |
| Gene Expression | ✔ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 1138 | 1716 | 486 | 1566 | 1979 | 1884 | 1583 | 1340 | 3117 | 3600 | 2069 | 2906 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 666.08 | 737.90 | 865.07 | 859.73 | 684.56 | 725.42 | 878.13 | 889.97 | 677.81 | 731.37 | 875.06 | 873.67 |
| Standard Deviation | 288.76 | 93.21 | 99.24 | 127.39 | 78.55 | 93.94 | 110.56 | 114.84 | 185.58 | 93.80 | 108.15 | 122.69 |
| Intensity Change Log 2 | — | 0.147730 | 0.377121 | 0.368188 | — | 0.083640 | 0.359258 | 0.378580 | — | 0.115602 | 0.368095 | 0.373464 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000564 | 0.000951 | 0.003968 | 0.007414 | 0.000434 | 0.000629 | 0.001999 | 0.023761 | 0.000482 | 0.000783 | 0.002461 | 0.014952 |
| Bud Neck | 0.029499 | 0.015048 | 0.016679 | 0.032574 | 0.024875 | 0.009001 | 0.012529 | 0.023613 | 0.026564 | 0.011883 | 0.013504 | 0.028442 |
| Bud Site | 0.022099 | 0.026697 | 0.052515 | 0.111462 | 0.022994 | 0.009066 | 0.054173 | 0.161283 | 0.022668 | 0.017470 | 0.053784 | 0.134435 |
| Cell Periphery | 0.000719 | 0.000309 | 0.000183 | 0.000249 | 0.000211 | 0.000221 | 0.000195 | 0.000559 | 0.000396 | 0.000263 | 0.000192 | 0.000392 |
| Cytoplasm | 0.035361 | 0.016552 | 0.017138 | 0.112112 | 0.032259 | 0.006216 | 0.022720 | 0.097766 | 0.033392 | 0.011143 | 0.021409 | 0.105497 |
| Cytoplasmic Foci | 0.126902 | 0.082603 | 0.088386 | 0.144681 | 0.139115 | 0.071362 | 0.091644 | 0.153591 | 0.134656 | 0.076720 | 0.090879 | 0.148790 |
| Eisosomes | 0.000171 | 0.000105 | 0.000098 | 0.000135 | 0.000126 | 0.000088 | 0.000081 | 0.000273 | 0.000142 | 0.000096 | 0.000085 | 0.000199 |
| Endoplasmic Reticulum | 0.003167 | 0.000527 | 0.004753 | 0.003728 | 0.000770 | 0.000243 | 0.001527 | 0.003245 | 0.001645 | 0.000379 | 0.002285 | 0.003505 |
| Endosome | 0.096668 | 0.097500 | 0.115107 | 0.072759 | 0.094721 | 0.103935 | 0.104769 | 0.059615 | 0.095432 | 0.100867 | 0.107198 | 0.066698 |
| Golgi | 0.070121 | 0.122521 | 0.080525 | 0.052372 | 0.103702 | 0.162391 | 0.108417 | 0.081539 | 0.091442 | 0.143386 | 0.101865 | 0.065821 |
| Lipid Particles | 0.016978 | 0.002606 | 0.002231 | 0.003987 | 0.008315 | 0.006346 | 0.001764 | 0.002292 | 0.011478 | 0.004563 | 0.001874 | 0.003205 |
| Mitochondria | 0.480790 | 0.525449 | 0.256688 | 0.077059 | 0.467297 | 0.549437 | 0.314235 | 0.136866 | 0.472223 | 0.538002 | 0.300718 | 0.104637 |
| Mitotic Spindle | 0.011860 | 0.019000 | 0.147267 | 0.106750 | 0.010070 | 0.010416 | 0.122776 | 0.035105 | 0.010724 | 0.014508 | 0.128529 | 0.073713 |
| None | 0.002041 | 0.000809 | 0.000626 | 0.000986 | 0.000910 | 0.000512 | 0.000720 | 0.000261 | 0.001323 | 0.000654 | 0.000698 | 0.000651 |
| Nuclear Periphery | 0.000942 | 0.000093 | 0.001463 | 0.000914 | 0.000220 | 0.000180 | 0.001088 | 0.000215 | 0.000484 | 0.000139 | 0.001176 | 0.000592 |
| Nuclear Periphery Foci | 0.000573 | 0.000177 | 0.001699 | 0.001045 | 0.000261 | 0.000128 | 0.000799 | 0.000469 | 0.000375 | 0.000151 | 0.001010 | 0.000779 |
| Nucleolus | 0.002656 | 0.000771 | 0.004452 | 0.001931 | 0.001214 | 0.001014 | 0.001925 | 0.000505 | 0.001741 | 0.000898 | 0.002519 | 0.001273 |
| Nucleus | 0.009858 | 0.001935 | 0.018127 | 0.041661 | 0.004847 | 0.001725 | 0.008958 | 0.009985 | 0.006676 | 0.001825 | 0.011112 | 0.027055 |
| Peroxisomes | 0.035349 | 0.044839 | 0.067840 | 0.061723 | 0.030896 | 0.027778 | 0.043994 | 0.132243 | 0.032522 | 0.035910 | 0.049596 | 0.094241 |
| Vacuole | 0.033352 | 0.024891 | 0.082076 | 0.152019 | 0.036937 | 0.020867 | 0.073141 | 0.068915 | 0.035628 | 0.022785 | 0.075240 | 0.113698 |
| Vacuole Periphery | 0.020329 | 0.016617 | 0.038179 | 0.014440 | 0.019825 | 0.018446 | 0.032544 | 0.007900 | 0.020009 | 0.017574 | 0.033867 | 0.011424 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -2.61 | -2.94 | -7.48 | -7.00 | -1.98 | -1.18 | -5.38 | -11.16 | -11.04 | -10.28 | -2.76 | -5.62 | -13.20 | -12.87 | -10.70 |
| Bud Neck | 5.12 | 3.76 | -1.18 | -8.73 | -6.02 | 7.65 | 5.97 | 0.58 | -8.58 | -6.63 | 8.75 | 7.50 | -1.16 | -12.46 | -10.88 |
| Bud Site | -1.70 | -5.99 | -17.98 | -17.53 | -8.02 | 8.08 | -9.78 | -23.54 | -26.50 | -16.63 | 3.31 | -11.51 | -29.49 | -31.53 | -17.85 |
| Cell Periphery | 2.16 | 2.84 | 2.57 | 1.98 | -1.87 | -0.28 | 0.44 | -5.05 | -5.24 | -5.85 | 1.81 | 2.81 | 0.25 | -3.29 | -5.83 |
| Cytoplasm | 6.22 | 4.65 | -16.52 | -22.37 | -19.83 | 12.58 | 3.39 | -15.40 | -23.18 | -17.72 | 12.67 | 5.25 | -22.95 | -32.16 | -26.61 |
| Cytoplasmic Foci | 8.32 | 6.02 | -1.69 | -11.61 | -8.17 | 16.00 | 10.70 | -2.54 | -16.92 | -12.27 | 17.45 | 12.08 | -2.46 | -20.20 | -14.61 |
| Eisosomes | 4.77 | 5.00 | 2.63 | -3.31 | -3.66 | 5.17 | 6.77 | -8.62 | -11.17 | -11.79 | 6.69 | 8.64 | -5.40 | -11.31 | -12.89 |
| Endoplasmic Reticulum | 2.12 | -1.16 | -0.59 | -9.37 | 1.08 | 5.55 | -4.64 | -4.39 | -5.39 | -2.87 | 2.75 | -1.41 | -3.53 | -10.05 | -3.18 |
| Endosome | -0.14 | -2.12 | 5.85 | 6.90 | 6.45 | -2.02 | -2.11 | 8.94 | 10.51 | 10.84 | -1.54 | -2.83 | 10.36 | 12.21 | 12.39 |
| Golgi | -9.73 | -1.33 | 5.35 | 15.93 | 5.32 | -10.20 | -0.72 | 4.98 | 14.08 | 5.43 | -12.95 | -2.28 | 8.94 | 21.44 | 10.17 |
| Lipid Particles | 7.44 | 7.62 | 6.72 | -2.92 | -3.61 | 1.77 | 7.58 | 7.18 | 4.59 | -1.46 | 7.05 | 10.68 | 9.28 | 2.43 | -4.28 |
| Mitochondria | -3.42 | 13.21 | 37.30 | 49.86 | 12.77 | -7.67 | 14.27 | 34.55 | 42.44 | 18.15 | -7.98 | 18.99 | 53.04 | 65.90 | 26.01 |
| Mitotic Spindle | -3.36 | -12.84 | -17.46 | -15.94 | 3.68 | -0.22 | -21.50 | -8.76 | -8.56 | 15.31 | -2.95 | -25.00 | -19.32 | -17.93 | 10.21 |
| None | 1.62 | 1.81 | 1.25 | -0.74 | -1.15 | 2.28 | 1.06 | 5.03 | 1.98 | 4.10 | 2.22 | 2.06 | 2.00 | -0.21 | 0.13 |
| Nuclear Periphery | 2.03 | -0.96 | -0.26 | -7.12 | 1.08 | 0.36 | -2.08 | -0.03 | -0.38 | 2.07 | 2.09 | -1.92 | -1.07 | -5.68 | 1.52 |
| Nuclear Periphery Foci | 2.86 | -2.81 | -2.82 | -5.28 | 1.23 | 2.46 | -2.59 | -1.99 | -3.45 | 1.33 | 3.55 | -3.43 | -4.02 | -6.32 | 0.69 |
| Nucleolus | 3.97 | -1.35 | 0.94 | -4.20 | 1.61 | 0.59 | -2.11 | 2.85 | 1.27 | 4.93 | 2.91 | -1.87 | 1.26 | -2.09 | 2.58 |
| Nucleus | 6.38 | -2.62 | -10.85 | -13.72 | -5.58 | 3.72 | -3.37 | -4.56 | -7.44 | -0.50 | 7.00 | -3.82 | -12.15 | -15.08 | -7.87 |
| Peroxisomes | -2.51 | -4.48 | -5.61 | -3.18 | 1.32 | 1.27 | -3.98 | -16.96 | -17.58 | -14.00 | -1.47 | -5.64 | -16.90 | -15.73 | -10.25 |
| Vacuole | 3.37 | -8.41 | -25.05 | -27.42 | -11.42 | 6.83 | -10.46 | -9.34 | -14.00 | -0.19 | 7.34 | -13.55 | -25.16 | -29.78 | -11.85 |
| Vacuole Periphery | 2.34 | -4.82 | 4.77 | 2.68 | 7.04 | 0.94 | -6.68 | 10.71 | 8.62 | 14.02 | 2.31 | -8.22 | 9.94 | 7.44 | 14.43 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Mitochondrial glycine transporter; required for the transport of glycine into mitochondria for initiation of heme biosynthesis, with YMC1 acting as a secondary transporter; homolog of human SLC25A38, a mitochondrial glycine transporter associated with nonsyndromic autosomal recessive congenital sideroblastic anemia; human SLC25A38 can complement the heme deficiency associated with the null mutant; GFP-fusion protein is induced in response to the DNA-damaging agent MMS |
| Localization | |
| Cell Percentages | mitochondrion (86%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | mito-1 |
Hem25
Hem25
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Hem25-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
