Standard name
Human Ortholog
Description Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.2 0.16 0.14 0.29 0.17 0.05 0.07 0.07 0.07 0.06 0 0.19 0.07 0 0.13 0.08 0.08 0.06 0.05 0 0.06 0.1 0.05
Bud 0.07 0.07 0.05 0.08 0.07 0.06 0.06 0 0.08 0.06 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.21 0.19 0.31 0.29 0.25 0.15 0.09 0.07 0.07 0.09 0.13 0.48 0.44 0.34 0.66 0.7 0.84 0.08 0.06 0.12 0.19 0.27 0.26
Cytoplasm 0.25 0.34 0.43 0.45 0.44 0.61 0.74 0.76 0.74 0.68 0.75 0.29 0.52 0.72 0.23 0.24 0.27 0 0.12 0.06 0 0 0.07
Endoplasmic Reticulum 0.48 0.49 0.27 0.2 0.34 0.22 0.17 0.11 0.07 0.1 0.05 0.41 0.33 0.23 0 0.05 0.05 0.74 0.59 0.6 0.58 0.5 0.46
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.12 0.16 0.11 0 0 0 0 0 0 0 0 0.06 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 31 41 22 45 31 12 22 26 18 13 8 34 19 11 17 7 5 11 15 8 8 27 15
Bud 11 18 8 12 13 15 18 17 21 13 20 2 6 4 3 2 0 3 4 1 0 0 2
Bud Neck 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 10 9 5 4 11
Bud Site 1 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0
Cell Periphery 32 47 50 45 44 35 29 27 17 21 30 86 122 92 86 64 54 16 18 25 28 74 79
Cytoplasm 39 86 69 70 79 142 229 290 184 153 169 51 143 194 30 22 17 8 36 13 5 12 21
Endoplasmic Reticulum 75 125 43 31 61 52 51 43 18 23 11 73 90 61 1 5 3 148 182 126 86 139 141
Endosome 0 0 0 0 0 1 1 7 0 2 0 0 0 1 2 0 0 0 3 1 0 2 4
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 7 6 0 0 5 0 0 2 3
Mitochondria 0 0 2 5 3 7 11 11 31 36 24 0 0 2 2 3 0 1 7 12 4 6 10
Nucleus 1 3 1 0 0 0 6 3 1 3 1 0 0 0 0 1 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 2 5 1 2 5 5 20 3 3 9 0 1 0 4 0 0 4 19 11 5 7 7
Unique Cell Count 155 254 159 154 179 233 308 384 250 225 224 178 275 271 130 91 64 201 309 213 149 281 306
Labelled Cell Count 190 322 201 211 234 269 373 445 294 268 274 246 381 366 152 110 79 201 309 213 149 281 306


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.6 10.8 8.8 8.7 8.6 6.8 6.6 7.0 6.0 5.4 5.9 9.5 9.0 8.0 18.3 17.6 18.6 9.3 8.9 8.8
Std Deviation (1e-4) 1.7 1.8 1.0 1.2 1.1 1.0 1.0 1.3 1.1 1.0 0.9 1.3 1.1 1.4 3.4 3.0 2.9 1.2 1.3 1.8
Intensity Change (Log2) -0.02 -0.03 -0.39 -0.43 -0.34 -0.55 -0.71 -0.58 0.1 0.03 -0.13 1.05 1.0 1.07 0.08 0.01 -0.0

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 3.3 0.9 -3.0 -2.3 -2.6 -2.2 -2.7 -3.7 1.3 -2.4 -3.7 -0.2 -1.5 -1.2
Bud 1.0 0.8 0.6 0.4 -0.3 1.3 0.3 1.4 0 -1.6 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.4 -1.4 -3.9 -6.0 -7.4 -6.6 -5.5 -4.3 3.2 2.7 0.5 5.9 5.9 7.2
Cytoplasm 0.4 0.1 3.4 6.6 7.2 6.1 4.8 6.4 -2.8 1.7 5.8 -3.6 -3.0 -2.3
Endoplasmic Reticulum -1.4 1.4 -1.1 -2.7 -4.6 -5.5 -4.3 -6.1 2.7 1.2 -1.1 -6.2 -4.2 -3.7
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 4.0 4.8 3.6 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 1.0 0 0 0.4 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.5385 11.204 10.4568 9.351 9.4603 10.2885 9.1932 11.6478 9.9989 8.4623 9.1523 10.3557 7.6542 10.1389 8.9424 8.4269 5.6634 9.482
Actin 0.0104 0.0005 0.0013 0.0004 0.0004 0.0004 0.0174 0.0003 0.0094 0.0169 0.0149 0.0005 0.0301 0.0003 0.0151 0.0133 0.0196 0.0002
Bud 0.0006 0.0001 0.0002 0.0002 0.0001 0.0001 0.0002 0 0.0004 0.0004 0.0004 0.0002 0.0005 0 0.0002 0.0003 0.003 0
Bud Neck 0.0006 0.0002 0.0004 0.0003 0.0005 0.0007 0.0009 0.0001 0.0004 0.0006 0.0006 0.0006 0.0013 0.0001 0.0002 0.0005 0.0005 0.0005
Bud Periphery 0.0006 0 0.0002 0.0001 0 0.0001 0.0003 0 0.0005 0.0002 0.0006 0.0002 0.0005 0 0.0002 0.0001 0.0037 0
Bud Site 0.001 0.0003 0.0007 0.0001 0.0002 0.0001 0.0009 0.0002 0.002 0.0008 0.0016 0.0002 0.0065 0.0001 0.0011 0.0017 0.0106 0
Cell Periphery 0.0004 0.0001 0.0003 0.0001 0.0001 0.0001 0.0003 0 0.0002 0.0001 0.0001 0 0.0002 0 0 0.0001 0.0004 0
Cytoplasm 0.8991 0.969 0.9277 0.8731 0.9407 0.9696 0.879 0.9931 0.9148 0.8576 0.9245 0.9676 0.8491 0.9924 0.9374 0.8887 0.6251 0.9774
Cytoplasmic Foci 0.0138 0.0017 0.0025 0.0042 0.0047 0.0033 0.017 0.0012 0.0063 0.0175 0.0068 0.0023 0.0169 0.0009 0.0089 0.0207 0.0371 0.0019
Eisosomes 0.0002 0 0.0002 0 0 0 0.0003 0 0 0.0001 0.0001 0 0.0002 0 0.0001 0.0001 0.0003 0
Endoplasmic Reticulum 0.0222 0.0184 0.0459 0.0737 0.016 0.0151 0.0188 0.0026 0.0146 0.0087 0.0099 0.0177 0.0162 0.0035 0.0057 0.047 0.0124 0.0124
Endosome 0.0091 0.0016 0.0033 0.0221 0.0281 0.0045 0.0266 0.0006 0.0172 0.0467 0.0183 0.0052 0.0188 0.0005 0.0089 0.0084 0.0542 0.0027
Golgi 0.0017 0.0002 0.0004 0.0005 0.0007 0.0004 0.0065 0.0001 0.0032 0.0183 0.0077 0.0004 0.0057 0.0001 0.0039 0.0026 0.0224 0.0002
Lipid Particles 0.0038 0.0002 0.0003 0.0001 0.0001 0 0.0039 0.0001 0.0037 0.007 0.0021 0 0.0051 0 0.0019 0.0034 0.0699 0
Mitochondria 0.0012 0.0001 0.0002 0.0008 0.0002 0.0006 0.0024 0 0.0071 0.0066 0.0051 0.0007 0.0089 0 0.0043 0.0007 0.0094 0.0001
None 0.0168 0.0012 0.008 0.0027 0.0016 0.0011 0.0119 0.0006 0.0022 0.0022 0.0009 0.0005 0.0076 0.0009 0.0015 0.002 0.011 0.0018
Nuclear Periphery 0.0039 0.0037 0.0026 0.0056 0.0015 0.001 0.0036 0.0003 0.0061 0.0061 0.0017 0.001 0.0089 0.0004 0.0013 0.0037 0.0076 0.0008
Nucleolus 0.0003 0 0.0003 0 0 0 0.0002 0 0.0002 0.0002 0.0001 0.0001 0.0007 0 0.0001 0.0001 0.0012 0
Nucleus 0.0024 0.0015 0.0019 0.0021 0.0014 0.0014 0.002 0.0006 0.0024 0.0027 0.0015 0.0016 0.011 0.0006 0.001 0.0016 0.0038 0.0014
Peroxisomes 0.0061 0 0.0001 0 0 0 0.0032 0 0.0042 0.0025 0.0005 0.0001 0.0036 0 0.0066 0.0018 0.0949 0
Punctate Nuclear 0.0037 0.0002 0.0011 0.0002 0.0001 0.0001 0.0029 0 0.0012 0.0024 0.0006 0.0004 0.0052 0 0.0009 0.0026 0.0066 0.0001
Vacuole 0.0017 0.001 0.0022 0.0113 0.0028 0.0012 0.0012 0.0002 0.0027 0.0016 0.0016 0.0005 0.002 0.0001 0.0005 0.0006 0.0045 0.0002
Vacuole Periphery 0.0003 0.0001 0.0002 0.0023 0.0008 0.0003 0.0005 0 0.0012 0.0008 0.0005 0.0002 0.0008 0 0.0003 0.0002 0.0019 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 50.1754 42.2153 52.1089 49.2596 50.6307 49.9207 46.788 43.7671 41.7157 50.8167
Translational Efficiency 0.7491 0.8111 0.6492 0.6862 0.5221 0.449 0.6544 0.5998 0.5771 0.5566

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1590 220 244 1355 1843 1553 1881 309 3433 1773 2125 1664

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1080.22 1349.37 1733.71 1481.46 1073.37 1142.96 1354.52 1543.64 1076.54 1168.57 1398.06 1493.01
Standard Deviation 153.79 203.71 222.33 188.89 170.32 220.46 203.98 223.53 162.91 228.80 239.00 197.27
Intensity Change Log 2 0.320961 0.682537 0.455695 0.090627 0.335634 0.524189 0.210751 0.520037 0.490239

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000182 0.000537 0.001246 0.001136 0.000156 0.000657 0.000270 0.001429 0.000168 0.000642 0.000382 0.001190
Bud Neck 0.000634 0.001465 0.009643 0.003397 0.000854 0.001016 0.001437 0.004560 0.000752 0.001072 0.002379 0.003613
Bud Site 0.005657 0.015942 0.019182 0.019500 0.004884 0.012618 0.006368 0.029360 0.005242 0.013031 0.007839 0.021331
Cell Periphery 0.000150 0.000308 0.001059 0.000534 0.000137 0.000185 0.000126 0.001039 0.000143 0.000200 0.000233 0.000628
Cytoplasm 0.811596 0.742999 0.484008 0.742330 0.810616 0.796174 0.699704 0.635441 0.811070 0.789576 0.674937 0.722481
Cytoplasmic Foci 0.097517 0.133241 0.056348 0.039811 0.088752 0.095549 0.036679 0.067358 0.092812 0.100226 0.038937 0.044926
Eisosomes 0.000012 0.000015 0.000024 0.000016 0.000011 0.000014 0.000016 0.000037 0.000012 0.000015 0.000017 0.000020
Endoplasmic Reticulum 0.011370 0.006428 0.002921 0.000877 0.007857 0.005239 0.002384 0.000821 0.009484 0.005387 0.002446 0.000866
Endosome 0.003661 0.006740 0.014298 0.006650 0.004154 0.006455 0.004514 0.006885 0.003926 0.006490 0.005637 0.006694
Golgi 0.003757 0.004369 0.001601 0.002844 0.003151 0.005654 0.000789 0.003491 0.003432 0.005495 0.000882 0.002964
Lipid Particles 0.001751 0.005410 0.018884 0.014155 0.002600 0.003746 0.003692 0.034070 0.002207 0.003952 0.005436 0.017853
Mitochondria 0.000656 0.000179 0.000095 0.002011 0.000246 0.001095 0.000212 0.005492 0.000436 0.000982 0.000198 0.002657
Mitotic Spindle 0.001500 0.009568 0.008211 0.012114 0.000940 0.002230 0.002316 0.011522 0.001199 0.003140 0.002993 0.012004
None 0.004934 0.000653 0.001777 0.001774 0.004487 0.003154 0.002807 0.001099 0.004694 0.002844 0.002688 0.001649
Nuclear Periphery 0.000083 0.000105 0.001328 0.000146 0.000099 0.000095 0.000559 0.000155 0.000092 0.000096 0.000647 0.000148
Nuclear Periphery Foci 0.002620 0.008392 0.032970 0.014015 0.003849 0.004786 0.010425 0.024358 0.003280 0.005233 0.013014 0.015935
Nucleolus 0.000205 0.000145 0.000164 0.000212 0.000290 0.000433 0.000269 0.000107 0.000251 0.000397 0.000257 0.000193
Nucleus 0.020507 0.012187 0.076956 0.022080 0.023069 0.016307 0.059024 0.016171 0.021883 0.015795 0.061083 0.020983
Peroxisomes 0.000268 0.000881 0.000266 0.000762 0.000307 0.001111 0.000497 0.000865 0.000289 0.001082 0.000470 0.000781
Vacuole 0.031211 0.049239 0.268512 0.113635 0.042257 0.041924 0.167285 0.155146 0.037141 0.042832 0.178909 0.121343
Vacuole Periphery 0.001727 0.001199 0.000507 0.002001 0.001285 0.001557 0.000630 0.000593 0.001489 0.001513 0.000616 0.001740

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.91 -10.17 -4.90 -2.70 1.48 -2.68 -3.57 -7.38 -2.10 -6.38 -2.87 -7.16 -6.10 -2.07 -4.47
Bud Neck -5.18 -13.74 -13.33 -7.05 10.23 -1.78 -7.12 -11.06 -10.51 -8.14 -4.35 -13.77 -15.85 -13.52 -2.86
Bud Site -3.31 -7.91 -10.17 -0.45 2.20 -6.29 -2.49 -7.56 -4.71 -6.87 -6.81 -4.73 -13.13 -4.04 -8.86
Cell Periphery -3.87 -10.41 -9.65 -2.81 7.18 -3.44 1.47 -7.32 -6.61 -7.47 -4.27 -6.71 -12.29 -9.42 -7.85
Cytoplasm 4.83 23.24 17.83 4.34 -14.33 2.17 19.63 16.64 15.41 7.72 3.86 26.16 23.85 17.89 -0.49
Cytoplasmic Foci -3.59 7.59 15.72 9.82 3.47 -1.57 15.85 3.77 4.84 -6.40 -1.96 20.72 17.64 15.62 -2.43
Eisosomes -1.72 -9.92 -3.16 -0.67 6.49 -2.43 -4.31 -7.69 -5.90 -6.09 -2.48 -6.50 -6.49 -2.93 -1.87
Endoplasmic Reticulum 2.33 5.95 7.30 2.86 6.62 1.87 5.30 6.57 5.28 7.14 3.47 8.18 9.79 5.83 8.23
Endosome -2.97 -8.78 -1.18 1.89 7.22 -3.63 0.05 -0.71 1.79 -0.73 -4.63 -3.93 -1.02 2.72 1.23
Golgi -0.14 6.93 5.68 1.77 0.18 -3.28 9.05 2.91 4.60 -1.22 -2.90 11.11 6.51 5.71 -2.26
Lipid Particles -4.10 -10.07 -12.39 -6.70 3.30 -1.78 -4.74 -7.07 -6.63 -6.61 -3.02 -10.45 -13.72 -10.63 -9.47
Mitochondria 2.14 2.62 -0.28 -1.06 -1.16 -1.90 1.29 -0.88 -0.34 -0.93 -1.35 2.56 -0.94 -0.03 -1.43
Mitotic Spindle -1.90 -6.24 -4.17 0.52 1.69 -1.65 -2.80 -1.41 -0.89 -0.65 -2.32 -4.25 -4.68 -2.67 -2.50
None 5.97 5.12 4.81 -1.41 0.18 1.39 2.43 4.24 4.45 2.31 2.70 3.77 5.80 3.46 1.72
Nuclear Periphery -1.55 -13.75 -8.22 -4.32 12.49 0.13 -5.16 -6.11 -5.88 3.56 -0.55 -7.60 -10.88 -8.93 5.67
Nuclear Periphery Foci -5.49 -12.56 -13.84 -4.74 7.34 -2.44 -10.86 -8.26 -7.75 -4.89 -5.61 -15.94 -15.45 -12.19 -2.16
Nucleolus 1.78 0.29 -0.36 -2.14 -0.57 -1.98 0.99 6.50 4.27 4.92 -2.29 0.21 2.93 3.09 1.88
Nucleus 1.07 -9.99 -5.36 -2.81 8.70 5.55 -15.70 3.65 -0.22 16.01 5.09 -18.97 -3.42 -7.19 16.23
Peroxisomes -2.98 -1.89 -3.87 1.34 -3.10 -2.68 -0.75 -3.98 1.68 -1.14 -2.97 -0.90 -4.47 1.91 -1.12
Vacuole -4.10 -17.29 -28.92 -18.33 7.73 -0.05 -28.98 -16.88 -16.86 -5.36 -3.27 -34.34 -32.42 -30.20 0.57
Vacuole Periphery 1.12 5.35 2.02 0.35 -1.48 -1.08 3.68 6.59 5.74 1.01 0.02 4.90 2.38 2.15 -1.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ubp1

Ubp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ubp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available