Standard name
Human Ortholog
Description Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein; protein abundance increases in response to DNA replication stress; STF1 has a paralog, INH1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.12 0.16 0.12 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0.07 0.09 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.05 0 0
Golgi 0 0.06 0 0 0 0 – 0 0 0 0 0 0.06 0.11 0.13 0.64 0.49 0.55 0.05 0.07 0 0.1 0.08 0.1
Mitochondria 0.87 0.86 0.97 0.97 0.88 0.95 – 0.87 0.93 0.93 0.96 0.95 0.91 0.9 0.85 0.11 0.11 0.07 0.77 0.77 0.84 0.69 0.69 0.65
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0.05 0 0.07 0.09 – 0.07 0.07 0.05 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.08 0.14 – 0.18 0.13 0.15 0.11 0.11 0 0 0 0.05 0.06 0.09 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0.08 0 0 0 0 0.07 0 0 0.05 0.06 0.06 0.05
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.23 0.16 0.07 0 0.05 0 – 0 0 0 0 0 0.08 0.08 0.08 0.16 0.12 0.11 0 0.05 0 0 0 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 3 0 1 0 – 0 0 0 0 3 0 6 3 14 19 23 9 9 1 4 15 13
Bud 6 1 13 8 4 6 – 14 11 9 12 21 4 0 2 0 3 5 4 1 0 1 5 6
Bud Neck 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 1 0
Bud Site 2 0 7 0 1 1 – 2 1 2 7 8 1 0 0 0 0 1 – – – – – –
Cell Periphery 13 11 4 9 6 1 – 0 2 1 1 0 12 9 5 10 8 16 1 0 1 0 0 0
Cytoplasm 6 8 2 7 8 5 – 13 3 3 5 3 5 5 12 4 10 13 0 2 0 0 1 0
Endoplasmic Reticulum 4 5 2 1 0 2 – 0 0 2 2 3 2 5 2 3 7 4 2 2 0 0 1 0
Endosome 26 1 0 0 7 0 – 3 0 0 0 0 9 9 9 0 1 2 48 3 13 11 14 9
Golgi 26 17 1 1 1 0 – 0 0 0 3 0 22 57 60 76 57 101 47 21 7 23 34 38
Mitochondria 741 245 307 273 338 398 – 485 426 352 437 524 341 476 404 13 13 13 696 233 261 171 290 243
Nucleus 8 0 1 0 0 1 – 3 1 0 0 0 0 0 0 0 2 3 0 1 0 0 0 2
Nuclear Periphery 26 12 17 11 27 39 – 41 30 20 31 42 15 22 4 1 0 2 9 2 2 0 3 4
Nucleolus 33 7 13 11 31 57 – 102 59 57 49 58 15 16 4 6 7 16 3 2 0 3 6 6
Peroxisomes 12 2 3 3 7 3 – 3 7 3 5 6 31 23 21 3 4 13 25 4 16 15 26 18
SpindlePole 6 0 6 0 3 1 – 3 0 2 2 3 5 0 2 2 2 2 5 1 1 2 2 1
Vac/Vac Membrane 200 45 23 6 21 12 – 17 12 9 9 7 29 40 37 19 14 20 40 16 5 7 16 27
Unique Cell Count 852 285 318 282 382 419 555 456 380 456 549 374 528 475 119 116 185 900 304 313 248 424 376
Labelled Cell Count 1110 357 402 330 455 526 686 552 461 563 678 491 668 565 151 147 234 900 304 313 248 424 376


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.9 11.2 5.5 8.1 11.4 11.3 – 12.8 12.6 13.3 14.5 14.3 12.8 14.9 15.0 29.4 28.6 27.1 10.1 11.8 12.5
Std Deviation (1e-4) 1.5 2.4 1.2 1.9 2.8 3.3 – 4.2 4.6 5.1 6.6 5.9 4.8 4.0 4.4 10.0 10.7 9.9 2.9 5.9 5.9
Intensity Change (Log2) – – – 0.56 1.06 1.05 – 1.23 1.21 1.29 1.41 1.39 1.22 1.44 1.46 2.42 2.39 2.31 0.88 1.12 1.19

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 6.5 5.6
Bud -0.8 -2.6 -2.3 – -1.3 -1.3 -1.3 -1.1 -0.2 -2.6 0 -3.7 0 0 -0.8
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 -0.7 -0.8 0 0 0 0 0 0
Cell Periphery 1.6 0 0 – 0 0 0 0 0 1.7 0 0 0 0 4.1
Cytoplasm 0 0 0 – 1.9 0 0 0 0 0 0 2.0 0 0 4.1
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 4.1 5.8 6.4 15.5 13.2 14.6
Mitochondria 0.2 -3.9 -1.0 – -4.5 -1.9 -2.2 -0.5 -0.8 -2.9 -3.4 -5.2 -18.0 -17.9 -20.1
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery -0.8 0.9 2.0 – 1.2 0.7 0 0.8 1.3 -0.8 -0.8 -3.9 0 0 -2.4
Nucleolus -0.1 2.2 4.4 – 6.0 4.2 4.8 3.4 3.4 -0.1 -0.8 -3.1 0.4 0.9 2.1
Peroxisomes 0 0 0 – 0 0 0 0 0 4.5 2.8 2.8 0 0 3.7
SpindlePole 0 0 0 – 0 0 0 0 0 -0.6 0 0 0 0 0
Vacuole -2.9 -0.9 -2.8 – -2.8 -3.0 -3.1 -3.6 -4.6 0.3 0.2 0.3 2.8 1.6 1.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.3815 11.0458 10.712 11.0255 10.5009 10.8036 10.447 9.6268 9.9383 8.814 11.7771 10.2185 14.1701 12.1453 12.0996 10.8299 10.4871 12.4432
Actin 0.0031 0.0013 0.0013 0.0002 0.0005 0.001 0.0198 0.0144 0.0138 0.0117 0.0183 0.0029 0.0086 0.0022 0.0135 0.0014 0.0012 0.0006
Bud 0.0001 0.0001 0 0 0 0.0001 0.0003 0.0001 0.0001 0.0003 0.0003 0.0001 0.0001 0.0003 0 0.0004 0.0001 0
Bud Neck 0 0 0 0 0 0 0.0003 0.0001 0.0001 0.0002 0.0003 0.0001 0.0003 0.0001 0.0001 0.0008 0 0
Bud Periphery 0.0002 0.0003 0.0001 0 0 0.0002 0.0004 0.0002 0.0003 0.0006 0.0006 0.0003 0.0002 0.0009 0.0001 0.0005 0.0001 0.0002
Bud Site 0.0002 0.0001 0.0001 0 0 0.0001 0.001 0.0003 0.0003 0.0005 0.0012 0.0001 0.0002 0.0008 0.0001 0.0167 0.0002 0
Cell Periphery 0.0001 0.0001 0.0001 0 0 0 0.0002 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0.0008 0.0001 0.0002 0.0001 0.0001
Cytoplasm 0.0001 0 0.0001 0 0 0.0002 0.0009 0.0001 0.0001 0.0001 0.0029 0.0002 0.0016 0 0 0.0004 0.0006 0
Cytoplasmic Foci 0.0018 0.001 0.0021 0.0001 0.0007 0.0007 0.0035 0.0027 0.006 0.0053 0.0045 0.0009 0.0018 0.0011 0.0011 0.012 0.0076 0.0002
Eisosomes 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0003 0.0002 0.0003 0.0001 0.0007 0.0003 0.0002 0.0002 0.0002 0.0001 0.0003 0.0001
Endoplasmic Reticulum 0 0.0001 0.0001 0 0 0 0.0011 0.0001 0.0001 0.0001 0.0022 0.0002 0.0007 0.0001 0.0001 0.0001 0.0001 0.0025
Endosome 0.0022 0.0061 0.003 0.0013 0.0055 0.0019 0.013 0.0101 0.0091 0.0088 0.0102 0.0116 0.0046 0.0056 0.0058 0.0037 0.0016 0.0016
Golgi 0.0125 0.0169 0.0048 0.0045 0.0542 0.0076 0.0347 0.0272 0.0113 0.0233 0.008 0.0053 0.005 0.0233 0.0169 0.0066 0.0022 0.0051
Lipid Particles 0.005 0.0072 0.0025 0.0003 0.0005 0.0005 0.0074 0.0052 0.0124 0.0028 0.0148 0.002 0.0144 0.0163 0.0024 0.0066 0.0147 0.0017
Mitochondria 0.9642 0.9494 0.9817 0.9922 0.9328 0.984 0.8976 0.9276 0.9263 0.9313 0.866 0.9702 0.9454 0.9277 0.9547 0.936 0.9579 0.9745
None 0 0 0.0001 0 0 0 0.0005 0 0.0001 0 0.0012 0 0.0013 0 0 0.0004 0.0008 0
Nuclear Periphery 0.0001 0.0006 0.0001 0 0 0 0.0015 0 0.0001 0 0.0253 0.0002 0.0014 0.0001 0 0.0001 0.0008 0.0004
Nucleolus 0.0001 0.0001 0 0 0 0 0.0002 0.0001 0.0034 0 0.0014 0.0001 0.0006 0.0003 0 0.0005 0.0038 0
Nucleus 0 0.0001 0 0 0 0 0.0003 0 0.0002 0 0.0085 0.0001 0.0014 0.0001 0 0.0002 0.0009 0
Peroxisomes 0.0044 0.0042 0.0015 0.0007 0.0008 0.0008 0.0088 0.0087 0.0049 0.014 0.0052 0.0019 0.0039 0.0098 0.0024 0.0101 0.0022 0.0093
Punctate Nuclear 0 0 0.0002 0 0 0 0.0005 0 0.0001 0.0001 0.0099 0.0001 0.0012 0 0 0.0008 0.0023 0
Vacuole 0.0011 0.003 0.0004 0.0001 0.0014 0.0003 0.0023 0.0008 0.0022 0.0002 0.0017 0.0013 0.0014 0.0031 0.0005 0.0009 0.0006 0.0005
Vacuole Periphery 0.0045 0.009 0.0016 0.0005 0.0033 0.0022 0.0054 0.002 0.0087 0.0004 0.0166 0.0018 0.0057 0.0072 0.002 0.0017 0.0019 0.0033

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 61.3002 15.1169 8.413 42.539 32.8876 29.5768 34.3905 30.9483 38.3676 47.874
Translational Efficiency 2.0706 3.6754 6.7647 2.5775 2.4825 6.2912 2.1754 3.3652 4.3091 2.5074

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
39 690 1649 1377 2082 1453 116 1281 2121 2143 1765 2658

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1083.65 942.77 2049.93 1450.02 788.99 966.86 2841.29 1490.20 794.41 959.10 2101.94 1469.38
Standard Deviation 229.17 162.61 465.72 424.80 429.15 172.45 976.57 430.89 428.15 169.72 551.15 428.21
Intensity Change Log 2 — -0.200921 0.919676 0.420174 — 0.293300 1.848467 0.917427 — 0.028220 1.385121 0.650851

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001353 0.001760 0.002476 0.007157 0.001318 0.001381 0.046632 0.005454 0.001318 0.001503 0.005378 0.006336
Bud Neck 0.000943 0.001345 0.002814 0.002821 0.001570 0.001579 0.022158 0.001679 0.001558 0.001504 0.004085 0.002271
Bud Site 0.000461 0.003772 0.001989 0.008597 0.005122 0.004167 0.005064 0.003639 0.005036 0.004040 0.002191 0.006207
Cell Periphery 0.000046 0.000148 0.000106 0.000476 0.000455 0.000232 0.001785 0.000217 0.000447 0.000205 0.000216 0.000351
Cytoplasm 0.000333 0.000675 0.000223 0.001374 0.004257 0.000684 0.000266 0.000545 0.004185 0.000681 0.000226 0.000975
Cytoplasmic Foci 0.017890 0.024654 0.029471 0.015898 0.005455 0.012803 0.026849 0.008983 0.005684 0.016619 0.029299 0.012565
Eisosomes 0.000328 0.000082 0.000546 0.000416 0.000051 0.000066 0.003073 0.000276 0.000056 0.000071 0.000712 0.000348
Endoplasmic Reticulum 0.000221 0.000219 0.000116 0.000506 0.000305 0.000149 0.010421 0.000293 0.000303 0.000172 0.000794 0.000403
Endosome 0.002252 0.026923 0.002036 0.011391 0.011561 0.024709 0.026428 0.007404 0.011389 0.025422 0.003639 0.009469
Golgi 0.006721 0.029082 0.019936 0.043641 0.007625 0.019263 0.167811 0.034322 0.007609 0.022425 0.029655 0.039149
Lipid Particles 0.002636 0.008276 0.010509 0.008761 0.002291 0.005323 0.098486 0.001921 0.002297 0.006274 0.016291 0.005464
Mitochondria 0.935209 0.855972 0.864934 0.848008 0.928323 0.900116 0.448528 0.901843 0.928450 0.885902 0.837566 0.873953
Mitotic Spindle 0.000942 0.009892 0.005459 0.005010 0.001575 0.002032 0.012461 0.004299 0.001563 0.004563 0.005920 0.004668
None 0.001022 0.000307 0.004601 0.002405 0.002057 0.000305 0.004923 0.001307 0.002038 0.000305 0.004622 0.001876
Nuclear Periphery 0.000255 0.000106 0.003691 0.001551 0.000033 0.000156 0.014223 0.000303 0.000037 0.000140 0.004383 0.000949
Nuclear Periphery Foci 0.006932 0.000245 0.001391 0.000613 0.000088 0.000223 0.005207 0.000215 0.000214 0.000230 0.001642 0.000421
Nucleolus 0.001328 0.000924 0.002443 0.000557 0.000358 0.000193 0.000506 0.000327 0.000376 0.000429 0.002316 0.000446
Nucleus 0.000165 0.000304 0.000155 0.000456 0.002194 0.000127 0.000200 0.000099 0.002156 0.000184 0.000158 0.000284
Peroxisomes 0.010139 0.024350 0.004470 0.005885 0.021415 0.014402 0.001304 0.006407 0.021208 0.017605 0.004262 0.006136
Vacuole 0.006833 0.005553 0.013685 0.011136 0.002245 0.006706 0.036938 0.008036 0.002329 0.006335 0.015214 0.009642
Vacuole Periphery 0.003991 0.005412 0.028948 0.023342 0.001706 0.005382 0.066736 0.012432 0.001748 0.005392 0.031431 0.018084

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.73 -2.07 -4.95 -4.63 -4.04 -0.10 -4.04 -3.90 -3.67 3.66 -0.36 -4.42 -6.07 -5.86 -0.85
Bud Neck -0.79 -3.95 -3.20 -2.96 -0.02 -0.02 -5.30 -0.33 -0.35 5.28 0.11 -5.13 -1.77 -2.38 4.09
Bud Site -2.61 -1.74 -4.87 -2.60 -4.15 0.70 0.04 1.08 0.36 1.03 0.79 2.57 -0.99 -2.00 -4.11
Cell Periphery -4.13 -3.34 -6.10 -4.52 -5.27 2.87 -2.96 3.18 0.36 3.53 3.30 2.98 1.18 -3.37 -2.72
Cytoplasm -0.26 0.73 -1.56 -2.12 -3.44 3.57 4.06 3.76 0.57 -2.40 3.61 4.12 3.23 -1.42 -4.14
Cytoplasmic Foci -0.59 -1.05 0.22 2.91 5.65 -5.35 -5.33 -2.92 2.61 4.42 -7.80 -11.62 -5.98 2.81 8.17
Eisosomes 1.64 -1.49 -0.60 -7.35 2.81 -1.49 -5.39 -8.15 -7.45 4.99 -1.30 -13.84 -11.93 -10.85 6.93
Endoplasmic Reticulum 0.47 1.07 -1.05 -3.75 -5.45 1.03 -3.00 0.08 -2.55 3.01 0.89 -1.79 -0.63 -4.90 1.68
Endosome -6.95 0.58 -3.33 5.34 -7.70 -5.46 -2.15 2.72 7.35 2.75 -6.97 6.29 1.40 8.62 -6.17
Golgi -6.27 -4.75 -9.50 -3.52 -6.79 -6.47 -8.74 -8.73 -4.46 7.20 -9.25 -9.97 -13.78 -6.49 -3.17
Lipid Particles -2.01 -4.48 -3.15 -0.20 1.23 -2.93 -5.43 0.64 3.36 5.45 -3.85 -8.80 -4.16 0.73 6.58
Mitochondria 2.02 1.80 2.31 0.66 1.95 3.86 14.15 3.59 -0.17 -13.28 6.27 12.03 8.47 1.80 -4.75
Mitotic Spindle -3.82 -3.95 -3.26 2.00 0.32 -0.80 -2.51 -2.40 -2.03 1.83 -3.50 -4.39 -3.71 -0.09 1.05
None 4.21 -12.89 -6.29 -13.78 8.12 2.86 -3.42 1.23 -11.50 6.38 2.88 -4.00 0.29 -17.30 11.90
Nuclear Periphery 1.82 -6.41 -5.38 -6.47 3.74 -3.95 -5.40 -7.02 -3.06 5.30 -4.56 -8.27 -7.75 -6.79 6.38
Nuclear Periphery Foci 1.04 0.95 1.01 -4.25 3.79 -2.87 -4.68 -3.23 0.14 4.56 0.41 -4.41 -0.42 -3.58 6.12
Nucleolus 0.30 -0.97 0.67 0.71 5.12 1.12 -0.87 0.20 -1.55 1.70 -0.24 -5.76 -0.40 -0.08 5.85
Nucleus -0.85 0.36 -0.84 -0.48 -0.96 3.34 3.22 3.37 0.44 1.88 3.24 3.29 2.95 -0.63 -0.80
Peroxisomes -2.26 0.98 0.72 6.10 -1.39 2.62 9.55 6.56 4.04 -4.70 1.43 8.13 7.08 7.03 -2.28
Vacuole 0.66 -0.55 -0.18 -3.91 1.82 -5.00 -5.29 -4.71 -1.04 4.35 -4.99 -11.41 -8.02 -3.51 4.44
Vacuole Periphery -0.52 -7.82 -5.97 -8.80 2.18 -5.01 -7.47 -7.69 -4.54 6.16 -6.28 -16.73 -13.71 -9.77 6.28
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein; protein abundance increases in response to DNA replication stress; STF1 has a paralog, INH1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (97%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Stf1

Stf1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Stf1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available