Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L41B; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41B has a paralog, RPL41A, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0.08 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 1.0 1.0 0.96 0.94 0.79 0.74 0.77 0.75 0.74 0.68 0.98 1.0 0.99 0.99 0.97 0.98 0.96 0.89 0.92 0.87 0.96 0.94
Endoplasmic Reticulum 0 0 0 0.05 0.05 0.18 0.22 0.19 0.16 0.19 0.22 0 0 0 0.06 0.06 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 4 6 10 15 12 30 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 2 0 0 0 1 4 0 2 1 0 0 1 0 0 0 0 4 0 2 0 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1 0 1 2 9 16 19 15 36 17 31 0 1 3 2 1 2 0 0 0 0 0 0
Cytoplasm 438 222 374 401 386 429 417 302 348 342 336 86 176 153 176 138 160 426 41 201 19 146 118
Endoplasmic Reticulum 2 0 1 19 21 96 127 73 73 87 109 1 0 0 10 8 15 2 0 4 0 2 2
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 9 3 12 11 8 16 0 0 1 0 1 0 0 0 1 0 0 0
Mitochondria 0 1 0 0 0 1 1 7 11 15 28 1 0 0 1 3 1 0 1 1 0 0 0
Nucleus 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 3 1 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 1 4 0 3 1 2 1 0 1 0 1 0 3 0 2 0 1 1
Unique Cell Count 442 223 375 419 410 541 565 393 461 463 495 88 176 155 177 142 163 447 47 219 22 153 126
Labelled Cell Count 442 225 376 422 416 558 584 421 500 485 553 90 178 158 189 152 178 447 47 219 22 153 126


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 179.0 103.2 145.0 118.0 83.4 68.1 62.0 57.9 51.5 48.9 45.5 173.1 177.2 165.3 259.0 237.9 241.8 211.2 211.5
Std Deviation (1e-4) 39.5 31.9 26.3 22.9 15.8 16.1 14.9 13.7 13.0 10.8 10.8 37.2 39.4 36.0 56.0 77.2 67.3 40.6 48.4
Intensity Change (Log2) 0.49 0.19 -0.31 -0.6 -0.74 -0.83 -1.0 -1.08 -1.18 0.75 0.78 0.68 1.33 1.2 1.23 1.03 1.04

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000100200300WT3HU80HU120HU1600100200300WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30100200300WT1AF140AF1800100200300
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 3.8 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 2.8 3.0 4.3 2.9 3.8 0 0 0 0 0 0
Cytoplasm 0.4 -2.7 -3.3 -7.2 -8.3 -7.6 -7.9 -8.2 -9.4 -1.5 0.9 -0.9 -0.2 -1.9 -1.3
Endoplasmic Reticulum 0 3.2 3.4 6.7 7.7 6.9 6.3 6.9 7.6 0 0 0 0 0 4.6
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 2.3 3.3 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 184.2252 253.9436 223.0844 219.3716 204.7563 106.1831 191.4682 225.4407 203.9917 191.9626 199.3631 213.8326 212.4937 281.701 246.9897 239.7586 160.4199 221.3297
Actin 0.0042 0.0002 0.0006 0.0017 0.0041 0.0002 0.0035 0.001 0.0017 0.0095 0.0004 0.0003 0.0017 0.0003 0.0172 0.0004 0.0059 0.001
Bud 0.0018 0.0008 0.0013 0.0018 0.005 0.0016 0.0023 0.0024 0.0027 0.0096 0.0029 0.0008 0.003 0.0014 0.002 0.0013 0.0032 0.0017
Bud Neck 0.0008 0.0009 0.001 0.0008 0.0016 0.0008 0.0009 0.0006 0.001 0.0008 0.0011 0.0008 0.0009 0.0005 0.0011 0.0009 0.0012 0.0005
Bud Periphery 0.0031 0.0008 0.0012 0.0017 0.0052 0.0023 0.0025 0.0012 0.0012 0.0225 0.0012 0.0002 0.0029 0.0005 0.0012 0.0008 0.0027 0.0008
Bud Site 0.0008 0.0009 0.0006 0.0007 0.0254 0.0004 0.001 0.0013 0.0011 0.002 0.0008 0 0.001 0.0007 0.0015 0.0005 0.0018 0.0002
Cell Periphery 0.0572 0.0625 0.0395 0.0299 0.0075 0.012 0.036 0.0199 0.0181 0.0182 0.0059 0.0002 0.03 0.014 0.0109 0.0442 0.0046 0.0025
Cytoplasm 0.5541 0.7464 0.6942 0.549 0.6007 0.2775 0.645 0.8701 0.7643 0.6399 0.6645 0.954 0.6509 0.8972 0.7745 0.6334 0.5664 0.722
Cytoplasmic Foci 0.0178 0.0007 0.0061 0.0012 0.0033 0.0033 0.0027 0.0018 0.0032 0.0009 0.0027 0.0017 0.0108 0.0008 0.0083 0.0013 0.0192 0.0011
Eisosomes 0.0006 0 0.0005 0.0003 0.0001 0.0004 0.0007 0 0.0005 0.0001 0 0 0.0003 0.0001 0.0002 0.0001 0.0011 0
Endoplasmic Reticulum 0.0361 0.014 0.0199 0.0031 0.002 0.0065 0.0301 0.01 0.009 0.0051 0.0026 0.005 0.0337 0.002 0.0054 0.0054 0.0048 0.0024
Endosome 0.0081 0.0018 0.0049 0.0034 0.0156 0.0115 0.0068 0.0021 0.0045 0.006 0.0156 0.0058 0.0058 0.0015 0.0031 0.0029 0.0679 0.0026
Golgi 0.0016 0.0004 0.0007 0.0003 0.0034 0.0005 0.0016 0.0007 0.0007 0.0007 0.0011 0.0002 0.0012 0.0002 0.0009 0.0002 0.0226 0.0002
Lipid Particles 0.0068 0.0023 0.0043 0.0011 0.0033 0.0027 0.0024 0.0008 0.0026 0.0007 0.0005 0 0.0026 0.0004 0.0022 0.0025 0.0128 0.0001
Mitochondria 0.0123 0.0011 0.0074 0.0294 0.0057 0.0168 0.0141 0.005 0.0137 0.0089 0.0016 0.0009 0.0226 0.0014 0.006 0.0013 0.0466 0.0033
None 0.0056 0.0002 0.0043 0.0012 0.001 0.0062 0.0023 0.0005 0.0018 0.0004 0.0005 0.0002 0.0042 0.0004 0.0028 0.0021 0.0175 0.0013
Nuclear Periphery 0.0324 0.0087 0.0117 0.0066 0.0134 0.0175 0.0428 0.0036 0.0095 0.0118 0.0079 0.0046 0.0352 0.0034 0.012 0.0283 0.0241 0.0359
Nucleolus 0.0159 0.0006 0.0094 0.0067 0.0042 0.1541 0.0028 0.0006 0.0065 0.0021 0.0015 0 0.0053 0.0011 0.0103 0.0045 0.0406 0.0054
Nucleus 0.0135 0.0038 0.0093 0.0098 0.029 0.0387 0.0142 0.0028 0.0087 0.0067 0.0158 0.004 0.0183 0.004 0.0113 0.0152 0.0116 0.0771
Peroxisomes 0.0015 0 0.0024 0.0004 0.0011 0.0003 0.0002 0.0001 0.0005 0.0001 0.0001 0 0.0008 0.0001 0.0031 0.0001 0.0021 0.0001
Punctate Nuclear 0.0016 0 0.0008 0.0001 0.0007 0.0004 0.0002 0 0.0003 0 0.0001 0 0.0063 0 0.0004 0.0002 0.001 0.0002
Vacuole 0.1907 0.1412 0.1535 0.2745 0.1905 0.2382 0.152 0.0666 0.1225 0.1906 0.2018 0.0151 0.1262 0.0578 0.0922 0.2243 0.084 0.0687
Vacuole Periphery 0.0335 0.0125 0.0267 0.0764 0.0773 0.2081 0.0361 0.0088 0.0257 0.0633 0.0713 0.0061 0.0361 0.0121 0.0334 0.0301 0.0582 0.0728

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8381.6299 10597.2209 15089.0943 7495.2046 13865.9326 14802.8833 9087.7947 9980.3939 14795.6837 7201.948
Translational Efficiency 2.4131 2.1354 1.287 4.1145 1.6052 1.1915 1.9337 2.0407 1.1932 2.1524

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
24 497 136 1141 1781 596 183 1545 1805 1093 319 2686

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 4730.27 11784.61 12873.86 10021.72 10235.93 11080.85 12306.83 9295.72 10162.72 11400.86 12548.57 9604.12
Standard Deviation 3472.84 2571.18 2365.38 2184.99 2055.51 2535.75 2658.93 2143.84 2174.17 2575.87 2553.38 2191.01
Intensity Change Log 2 1.316910 1.444450 1.083136 0.114426 0.265817 -0.139004 0.611462 0.750610 0.368196

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002649 0.000136 0.000119 0.000179 0.000033 0.000077 0.000139 0.000177 0.000068 0.000104 0.000130 0.000178
Bud Neck 0.003442 0.000539 0.004813 0.001208 0.000332 0.000641 0.006129 0.001256 0.000373 0.000594 0.005568 0.001236
Bud Site 0.004252 0.002659 0.001508 0.006088 0.000741 0.002718 0.006618 0.005967 0.000787 0.002691 0.004439 0.006018
Cell Periphery 0.091629 0.022534 0.050241 0.041304 0.017907 0.023233 0.024826 0.015352 0.018887 0.022915 0.035661 0.026376
Cytoplasm 0.062009 0.567518 0.178265 0.597213 0.621835 0.571552 0.320865 0.658392 0.614391 0.569717 0.260070 0.632403
Cytoplasmic Foci 0.041717 0.013307 0.030668 0.005923 0.008819 0.015189 0.022054 0.005350 0.009257 0.014333 0.025726 0.005594
Eisosomes 0.000068 0.000002 0.000011 0.000004 0.000002 0.000002 0.000006 0.000004 0.000002 0.000002 0.000008 0.000004
Endoplasmic Reticulum 0.004410 0.000531 0.000349 0.000529 0.000842 0.000409 0.000338 0.000175 0.000889 0.000465 0.000342 0.000325
Endosome 0.001175 0.000481 0.000710 0.000542 0.000426 0.000592 0.001435 0.000425 0.000436 0.000541 0.001126 0.000475
Golgi 0.057754 0.092613 0.101633 0.020009 0.083487 0.098338 0.038928 0.016672 0.083144 0.095735 0.065662 0.018090
Lipid Particles 0.022153 0.010756 0.032081 0.018231 0.012678 0.013823 0.034553 0.011552 0.012804 0.012428 0.033499 0.014389
Mitochondria 0.003750 0.000186 0.000169 0.000354 0.000110 0.000217 0.000209 0.001130 0.000159 0.000203 0.000191 0.000800
Mitotic Spindle 0.030193 0.000923 0.002558 0.000463 0.000735 0.001231 0.006060 0.001348 0.001127 0.001091 0.004567 0.000972
None 0.015918 0.002924 0.001439 0.001681 0.002601 0.003770 0.001418 0.002046 0.002778 0.003385 0.001427 0.001891
Nuclear Periphery 0.004455 0.001522 0.008641 0.000638 0.001539 0.001465 0.004289 0.000381 0.001578 0.001491 0.006144 0.000491
Nuclear Periphery Foci 0.033351 0.014839 0.027041 0.006697 0.018064 0.020272 0.035735 0.005273 0.018267 0.017801 0.032028 0.005878
Nucleolus 0.039589 0.000112 0.000204 0.000272 0.000062 0.000124 0.000255 0.000232 0.000588 0.000119 0.000233 0.000249
Nucleus 0.343851 0.013284 0.030326 0.018281 0.006404 0.014580 0.020383 0.015579 0.010890 0.013991 0.024622 0.016727
Peroxisomes 0.009966 0.000031 0.000011 0.000088 0.000005 0.000009 0.000032 0.000049 0.000138 0.000019 0.000023 0.000065
Vacuole 0.138209 0.097738 0.331832 0.229822 0.100067 0.104670 0.399717 0.222102 0.100574 0.101518 0.370775 0.225381
Vacuole Periphery 0.089459 0.157368 0.197382 0.050475 0.123312 0.127089 0.076013 0.036537 0.122862 0.140857 0.127756 0.042458

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.60 2.61 2.52 -1.06 -2.16 -3.52 -7.47 -3.78 -2.43 -0.67 -0.81 -3.45 -3.80 -2.12 -1.86
Bud Neck 2.19 -1.36 1.23 -6.12 4.50 -3.23 -4.27 -7.82 -5.76 3.52 -3.04 -5.69 -10.08 -8.22 4.54
Bud Site 1.24 1.72 -0.39 -4.05 -5.83 -2.89 -4.99 -8.43 -3.35 0.47 -4.11 -5.17 -10.56 -5.19 -2.07
Cell Periphery 2.31 1.30 1.75 -5.26 2.27 -2.72 -1.53 3.45 5.10 3.18 -2.55 -5.34 -3.23 -0.47 3.56
Cytoplasm -14.73 -2.81 -16.65 -1.19 -18.28 2.95 13.16 -1.98 -4.35 -14.18 3.23 20.17 -0.71 -4.13 -21.65
Cytoplasmic Foci 1.06 0.26 1.31 3.33 5.60 -4.32 -4.20 0.31 3.98 4.19 -4.27 -6.42 1.44 5.14 6.82
Eisosomes 1.82 1.59 1.75 -4.63 3.62 -2.00 -5.18 -1.97 -1.59 1.31 0.96 -5.62 -1.90 -2.80 3.15
Endoplasmic Reticulum 1.97 2.07 1.99 0.23 -1.29 3.09 4.01 5.22 3.92 2.69 3.01 4.32 4.27 2.04 0.11
Endosome 1.38 0.93 1.28 -0.47 1.51 -2.76 -6.55 -0.47 1.93 6.21 -2.20 -6.91 -0.84 0.93 6.09
Golgi -1.64 -1.80 1.58 14.05 10.97 -2.68 11.91 25.48 17.36 6.23 -2.81 4.66 25.45 22.32 11.40
Lipid Particles 1.55 -1.25 0.63 -3.88 4.43 -0.69 -5.05 1.30 1.56 5.32 0.37 -7.07 -1.16 -1.34 6.72
Mitochondria 3.18 3.18 3.00 -2.01 -2.05 -2.43 -2.51 -1.42 -1.23 -1.22 -1.36 -1.41 -1.58 -1.45 -1.45
Mitotic Spindle 1.08 1.01 1.09 3.22 3.88 -3.46 -3.36 -1.68 -0.79 2.72 0.10 -3.48 -0.14 -0.32 3.45
None 1.42 1.57 1.54 3.32 -1.05 -0.85 2.10 0.71 1.26 -1.59 -0.67 2.39 1.33 1.92 -1.88
Nuclear Periphery 1.74 -2.58 2.31 4.10 8.00 0.48 -2.59 7.36 8.42 3.55 0.53 -5.89 7.03 8.25 7.27
Nuclear Periphery Foci 1.50 0.79 2.02 5.44 9.46 -1.19 -3.65 14.95 8.90 6.12 0.46 -4.46 15.23 10.37 8.59
Nucleolus 2.72 2.71 2.71 -2.12 -0.92 -2.94 -4.33 -6.97 -4.27 0.40 2.16 1.44 1.35 -4.00 -0.37
Nucleus 4.14 3.85 4.00 -4.42 1.72 -5.22 -4.44 -10.62 -3.48 1.58 -2.04 -5.15 -6.91 -5.56 2.31
Peroxisomes 1.11 1.11 1.11 -1.25 -1.74 -2.58 -5.45 -6.33 -5.77 -2.14 1.03 1.00 0.74 -2.35 -2.23
Vacuole 0.76 -4.80 -2.71 -14.07 5.01 -0.64 -13.97 -16.91 -13.99 7.73 -0.24 -18.13 -21.19 -19.78 9.16
Vacuole Periphery -1.89 -2.61 0.97 11.86 10.18 -0.37 6.93 21.36 13.26 3.91 -2.54 0.72 20.32 17.75 9.50
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L41B; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41B has a paralog, RPL41A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Rpl41b

Rpl41b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl41b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available