Standard name
Human Ortholog
Description Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has a calmodulin-binding motif and binds calmodulin in vitro; INH1 has a paralog, STF1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.09 0.16 0.14 0 0 0 0 0 0.06
Bud 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.11 0.16 0.08 0 0 0 0 0 0
Cytoplasm 0.72 0.14 0.3 0.2 0.07 0 – 0 0 0 0 0 0.4 0.34 0.33 0.26 0.34 0.18 0.41 0 0.05 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.07 0 0.05 0 0 0 0 0 0
Endosome 0 0.07 0 0 0.26 0 – 0 0 0 0 0 0.3 0.14 0.23 0.13 0.09 0.12 0 0.05 0.1 0.09 0.1 0.08
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.28 0.28 0.26 0 0.08 0 0 0.05 0.05
Mitochondria 0.28 0.69 0.74 0.86 0.73 0.88 – 0.9 0.92 0.92 0.95 0.91 0.21 0.41 0.29 0.07 0.18 0.08 0.35 0.66 0.66 0.66 0.56 0.53
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.05 – 0.07 0.07 0.06 0.07 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.12 – 0.19 0.12 0.12 0.1 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0.08 0 0.12 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.12 0 0.05 0.14 0.08 – 0.06 0.05 0 0 0 0.13 0.08 0.13 0.23 0.11 0.26 0.06 0.05 0 0.06 0.07 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 3 3 1 0 0 – 0 0 0 0 1 0 1 2 8 12 9 6 9 7 4 7 13
Bud 1 4 13 8 5 5 – 18 7 12 11 15 3 5 4 3 3 0 3 1 0 1 3 7
Bud Neck 1 0 6 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 2 1 2 1 5 5
Bud Site 0 1 1 1 0 0 – 7 2 4 1 5 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 6 0 3 1 3 – 4 0 2 3 3 1 6 8 10 12 5 1 0 1 1 0 1
Cytoplasm 147 25 74 39 17 12 – 4 4 2 1 3 58 84 79 23 25 12 102 6 15 1 7 9
Endoplasmic Reticulum 0 7 4 2 0 4 – 1 2 0 2 4 0 4 8 6 0 3 1 1 3 1 0 3
Endosome 4 12 1 2 65 7 – 2 2 3 0 1 43 35 55 12 7 8 9 9 28 14 23 20
Golgi 0 3 0 0 1 0 – 1 0 0 1 0 5 6 7 25 21 17 1 16 1 6 11 11
Mitochondria 58 122 184 169 182 287 – 378 283 317 276 322 30 101 71 6 13 5 85 137 191 106 126 126
Nucleus 1 2 3 0 1 4 – 2 1 1 0 2 0 2 1 1 0 1 1 1 0 0 0 1
Nuclear Periphery 0 0 1 0 4 16 – 28 22 19 20 32 0 0 0 0 0 0 0 0 1 1 0 2
Nucleolus 0 3 0 2 6 38 – 79 38 43 28 36 0 0 0 1 0 2 0 0 0 0 1 2
Peroxisomes 1 8 1 1 8 2 – 2 1 8 3 8 11 11 30 0 0 0 1 6 7 5 9 5
SpindlePole 1 1 7 1 7 2 – 3 2 5 3 4 5 2 2 3 2 1 6 1 10 3 7 9
Vac/Vac Membrane 20 22 6 10 35 25 – 27 15 10 10 8 19 20 32 21 8 17 14 10 6 10 16 13
Unique Cell Count 205 178 248 197 251 325 421 308 344 292 353 144 245 242 90 74 66 247 208 288 163 225 238
Labelled Cell Count 235 219 304 240 332 405 556 379 426 359 444 175 277 299 119 103 80 247 208 288 163 225 238


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.3 7.2 3.5 4.1 5.7 5.8 – 7.7 9.1 10.1 10.7 11.8 5.7 6.0 5.6 9.9 9.3 9.6 6.3 6.1 6.5
Std Deviation (1e-4) 2.1 2.6 0.8 1.8 1.5 1.7 – 3.0 4.2 4.9 5.3 5.7 2.5 2.6 1.3 3.6 2.2 2.4 5.4 3.1 4.4
Intensity Change (Log2) – – – 0.25 0.72 0.73 – 1.15 1.39 1.54 1.63 1.77 0.71 0.79 0.69 1.51 1.42 1.47 0.86 0.81 0.9


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 -1.9 -2.5 – -0.6 -1.9 -1.0 -0.8 -0.6 -1.5 -1.9 -2.2 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -2.4 -6.7 -8.7 – -11.2 -9.6 -10.5 -9.9 -10.5 2.1 1.1 0.7 -0.8 0.6 -1.9
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 1.2 0 0 0
Endosome 0 8.4 0 – 0 0 0 0 0 8.9 5.9 7.8 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 8.6 0 0
Mitochondria 0 -0.4 4.4 – 5.3 5.7 6.0 6.6 5.6 -10.2 -7.4 -9.9 -11.1 -8.8 -9.8
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 3.2 – 3.8 4.0 3.4 3.9 4.6 0 0 0 0 0 0
Nucleolus 0 0 5.6 – 7.3 5.7 5.8 5.0 5.2 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 2.9 5.5 0 0 0
SpindlePole 0 0 0 – 0 0 -1.2 0 0 0 0 0 0 0 0
Vacuole 1.5 4.7 2.8 – 2.3 1.5 0.4 0.7 -0.1 4.2 2.9 4.5 6.3 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.9508 4.1066 4.365 3.298 3.5295 4.2107 3.7222 3.0879 3.0698 3.1288 2.9592 3.1651 10.9378 6.3585 7.0636 3.9449 5.4566 9.1735
Actin 0.0069 0.0169 0.0053 0.004 0.0035 0.002 0.0238 0.0314 0.038 0.02 0.0339 0.0075 0.0644 0.0252 0.0487 0.0442 0.0052 0.0218
Bud 0.0004 0.0017 0.0013 0.0003 0.0003 0.0002 0.0008 0.0028 0.0021 0.0007 0.002 0.0003 0.0035 0.005 0.006 0.0278 0.0013 0.0009
Bud Neck 0.0002 0.0004 0.0004 0.0001 0.0001 0.0002 0.0009 0.0005 0.0044 0.0007 0.0004 0.0004 0.0011 0.0007 0.0009 0.0008 0.0003 0.0016
Bud Periphery 0.0008 0.003 0.0018 0.0006 0.0006 0.0004 0.0014 0.0037 0.0057 0.001 0.0026 0.0007 0.0044 0.0097 0.0142 0.0412 0.0047 0.0024
Bud Site 0.0013 0.0105 0.0082 0.0002 0.0003 0.0002 0.0025 0.011 0.0087 0.0013 0.0031 0.0003 0.0046 0.0247 0.0057 0.0153 0.001 0.0017
Cell Periphery 0.0002 0.0003 0.003 0.0002 0.0001 0.0001 0.0004 0.0005 0.0008 0.0003 0.0002 0.0002 0.0005 0.0013 0.0019 0.0019 0.0009 0.001
Cytoplasm 0.0027 0.0017 0.001 0.0007 0.0004 0.0029 0.0036 0.0037 0.0037 0.0198 0.0029 0.0014 0.0695 0.0346 0.0523 0.0299 0.0106 0.0566
Cytoplasmic Foci 0.0174 0.0389 0.0145 0.0137 0.0171 0.012 0.0195 0.0335 0.0149 0.0264 0.0296 0.0135 0.0444 0.0442 0.0353 0.0222 0.0343 0.0383
Eisosomes 0.0002 0.0002 0.0004 0.0004 0.0002 0.0001 0.0007 0.0005 0.0005 0.0003 0.0003 0.0002 0.0005 0.0009 0.0004 0.0003 0.0022 0.0013
Endoplasmic Reticulum 0.0007 0.0003 0.0003 0.0005 0.0003 0.0005 0.0023 0.0005 0.0009 0.0012 0.0062 0.0004 0.0034 0.0007 0.0021 0.0203 0.0014 0.0014
Endosome 0.0335 0.0314 0.0284 0.0542 0.0442 0.0241 0.059 0.0736 0.034 0.0749 0.0648 0.0396 0.1027 0.0819 0.0773 0.1011 0.0885 0.0913
Golgi 0.0443 0.0761 0.0312 0.0371 0.0608 0.0409 0.0679 0.0875 0.0542 0.1314 0.0751 0.0585 0.1033 0.0901 0.0595 0.1167 0.1213 0.1071
Lipid Particles 0.0192 0.0092 0.005 0.0017 0.0017 0.0063 0.0199 0.0056 0.0059 0.0057 0.0218 0.0122 0.064 0.0185 0.0085 0.0101 0.0073 0.0193
Mitochondria 0.8424 0.7632 0.8688 0.8682 0.847 0.8928 0.7575 0.7164 0.7796 0.6855 0.6821 0.8422 0.4485 0.5985 0.6193 0.5273 0.5791 0.6127
None 0.0028 0.0009 0.0003 0.0001 0.0001 0.0004 0.002 0.0004 0.0014 0.0038 0.0008 0.0002 0.0052 0.0128 0.0054 0.0032 0.1055 0.0025
Nuclear Periphery 0.0005 0.0001 0.0003 0.0008 0.0002 0.0003 0.0022 0.0002 0.0056 0.0004 0.0228 0.0001 0.0146 0.0002 0.0009 0.0033 0.0005 0.0008
Nucleolus 0.0006 0.0007 0.0008 0.0001 0 0.0001 0.0011 0.0005 0.0006 0.0003 0.0002 0.0001 0.0005 0.0019 0.0016 0.0005 0.0005 0.0003
Nucleus 0.0003 0.0003 0.0003 0.0001 0.0001 0.0001 0.0009 0.0002 0.0033 0.0009 0.0024 0.0001 0.0027 0.0009 0.0016 0.0011 0.0005 0.0008
Peroxisomes 0.0102 0.0374 0.015 0.0027 0.0136 0.0117 0.0227 0.0207 0.0242 0.0099 0.0373 0.0173 0.0474 0.0395 0.0347 0.0071 0.0242 0.0288
Punctate Nuclear 0.0005 0.0002 0.0002 0 0.0001 0.0002 0.002 0.0001 0.0051 0.0003 0.0044 0.0002 0.0061 0.0003 0.0004 0.0008 0.0006 0.001
Vacuole 0.0049 0.004 0.0064 0.0044 0.0036 0.0011 0.005 0.0037 0.0041 0.0105 0.0034 0.0018 0.0044 0.005 0.0163 0.0151 0.0045 0.004
Vacuole Periphery 0.0099 0.0027 0.007 0.01 0.0056 0.0034 0.0038 0.003 0.0023 0.0048 0.0038 0.0029 0.0041 0.0035 0.0071 0.0099 0.0054 0.0043

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.6606 3.8232 2.837 16.3297 19.4075 17.0976 10.6304 14.3496 12.9379 12.9603
Translational Efficiency 1.7666 6.7196 8.8223 2.2143 2.6431 2.461 1.7361 1.7875 2.552 1.83

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
21 776 2173 1416 1728 1795 2558 1367 1749 2571 4731 2783

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 769.25 798.67 1188.42 1044.53 695.91 734.72 934.39 1087.54 696.79 754.02 1051.07 1065.66
Standard Deviation 252.47 197.99 226.78 228.30 376.89 91.22 181.01 240.23 375.72 136.03 239.51 235.22
Intensity Change Log 2 — 0.054147 0.627520 0.441329 — 0.078294 0.425124 0.644096 — 0.065666 0.534917 0.541197

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000275 0.005497 0.002224 0.008709 0.001469 0.000773 0.005757 0.021857 0.001455 0.002199 0.004135 0.015167
Bud Neck 0.023868 0.037840 0.003155 0.007719 0.032644 0.049005 0.010210 0.004047 0.032539 0.045635 0.006969 0.005915
Bud Site 0.002766 0.095455 0.064247 0.051225 0.025179 0.023059 0.075961 0.093678 0.024910 0.044910 0.070581 0.072078
Cell Periphery 0.000370 0.000809 0.000287 0.001179 0.000781 0.000292 0.000359 0.001356 0.000776 0.000448 0.000326 0.001266
Cytoplasm 0.085355 0.100868* 0.056847 0.020043 0.111904* 0.117943* 0.042162 0.028569 0.111585* 0.112789* 0.048907 0.024231
Cytoplasmic Foci 0.056940 0.182157* 0.072506 0.041571 0.285907* 0.278429* 0.057944 0.038906 0.283158* 0.249371* 0.064632 0.040262
Eisosomes 0.000326 0.000195 0.000039 0.000108 0.000404 0.000252 0.000080 0.000166 0.000403 0.000235 0.000061 0.000137
Endoplasmic Reticulum 0.001225 0.000965 0.001125 0.001949 0.001937 0.000740 0.000743 0.000998 0.001929 0.000808 0.000919 0.001482
Endosome 0.023653 0.063089 0.060487 0.076019 0.063693 0.094397 0.078078 0.047566 0.063213 0.084948 0.069998 0.062043
Golgi 0.075942 0.049998 0.212956* 0.102141 0.050982 0.060234 0.089882 0.112042* 0.051282 0.057144 0.146411* 0.107004
Lipid Particles 0.003645 0.005827 0.000555 0.004899 0.023445 0.015572 0.001029 0.000631 0.023207 0.012631 0.000811 0.002803
Mitochondria 0.697090* 0.264167* 0.241599* 0.489607* 0.243807* 0.190420* 0.418789* 0.530765* 0.249249* 0.212679* 0.337404* 0.509823*
Mitotic Spindle 0.002243 0.026160 0.093131 0.055544 0.007722 0.012997 0.098468 0.038415 0.007657 0.016970 0.096016 0.047131
None 0.000926 0.002395 0.000845 0.000633 0.001303 0.001322 0.000520 0.000367 0.001298 0.001646 0.000669 0.000502
Nuclear Periphery 0.000102 0.000212 0.000521 0.001938 0.000390 0.000303 0.000319 0.000091 0.000386 0.000276 0.000412 0.001031
Nuclear Periphery Foci 0.000064 0.000512 0.001015 0.002273 0.000339 0.000338 0.000391 0.000159 0.000336 0.000391 0.000678 0.001234
Nucleolus 0.000119 0.002144 0.000228 0.000897 0.001071 0.001649 0.000376 0.000062 0.001060 0.001799 0.000308 0.000487
Nucleus 0.003406 0.014368 0.002263 0.003246 0.027122 0.023940 0.003333 0.000443 0.026838 0.021051 0.002841 0.001869
Peroxisomes 0.009083 0.089310 0.006668 0.021348 0.073672 0.064959 0.037646 0.049212 0.072896 0.072309 0.023417 0.035035
Vacuole 0.002429 0.049062 0.086709 0.066590 0.034828 0.055155 0.054330 0.018145 0.034439 0.053316 0.069202 0.042794
Vacuole Periphery 0.010174 0.008970 0.092592 0.042361 0.011401 0.008219 0.023623 0.012525 0.011386 0.008446 0.055301 0.027706

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.17 -5.89 -6.18 -1.95 -4.64 3.51 -6.47 -9.99 -10.36 -7.55 -2.06 -6.56 -11.12 -10.30 -8.64
Bud Neck -0.72 1.08 0.85 9.07 -4.31 -5.11 11.03 14.82 17.11 8.39 -4.71 13.22 13.61 18.71 1.91
Bud Site -14.29 -21.76* -14.84 5.90 3.02 0.87 -15.20 -13.15 -13.84 -3.20 -6.62 -17.15 -13.86 -7.69 -0.55
Cell Periphery -2.90 0.72 -3.42 -1.55 -4.30 3.42 2.98 -2.10 -4.53 -4.26 2.27 3.24 -2.35 -5.09 -6.02
Cytoplasm -0.34 0.51 1.19 11.81 8.89 -1.10 14.27 16.54 17.47 3.87 -0.38 13.23 18.48 21.71 9.21
Cytoplasmic Foci -6.62 -0.87 0.85 18.15 10.15 0.92 40.43 43.67 42.44 7.04 4.79 40.03 44.40 45.05 11.96
Eisosomes 0.96 2.13 1.61 5.51 -8.08 5.33 12.97 9.18 5.43 -10.49 6.28 13.89 10.56 8.19 -12.56
Endoplasmic Reticulum 0.30 0.08 -0.91 -3.74 -3.43 3.74 4.13 3.01 -1.26 -1.60 3.72 3.50 1.42 -3.88 -3.93
Endosome -5.06 -5.25 -6.94 -2.53 -4.27 -7.26 -4.00 4.82 11.58 9.21 -5.94 -2.19 0.53 7.12 3.29
Golgi 0.76 -3.79 -0.69 -8.75 15.98 -2.64 -10.21 -11.36 -9.31 -3.96 -1.79 -25.28 -13.75 -12.42 8.66
Lipid Particles -1.30 1.90 -0.69 0.83 -4.50 4.42 16.04 16.28 13.18 2.05 6.60 16.26 13.95 10.28 -3.89
Mitochondria 5.54 5.86 2.75 -13.45 -20.34* 5.71 -16.91 -22.30 -27.52* -8.90 4.11 -9.72 -24.93 -31.18* -19.26
Mitotic Spindle -7.41 -23.70* -13.48 -6.35 7.20 -2.77 -24.23* -10.72 -8.39 13.55 -5.24 -31.98 -15.54 -11.36 14.23
None -2.29 0.16 0.58 3.58 3.31 -0.13 3.23 3.87 3.36 4.11 -1.20 2.66 3.34 4.64 4.49
Nuclear Periphery -1.82 -5.14 -3.80 -3.57 -2.90 0.90 0.41 4.33 3.09 1.81 1.34 -0.34 -2.54 -3.01 -2.38
Nuclear Periphery Foci -3.30 -9.62 -4.79 -3.48 -2.60 0.01 -0.40 2.85 1.37 1.71 -0.64 -3.44 -3.70 -3.22 -2.15
Nucleolus -4.72 -1.78 -4.11 2.86 -3.55 -2.32 4.70 7.73 6.99 6.10 -3.20 5.45 3.79 6.06 -1.46
Nucleus -4.01 0.36 -0.30 4.71 -1.33 1.27 11.63 13.67 14.36 4.36 2.43 12.25 12.60 13.70 1.29
Peroxisomes -11.87 0.61 -2.86 11.40 -6.90 2.00 9.39 5.14 3.47 -2.78 0.10 14.45 9.96 11.17 -4.91
Vacuole -12.65 -31.44 -18.82 -3.86 4.16 -6.61 -8.17 6.11 11.08 13.01 -7.24 -15.89 -4.39 2.70 9.74
Vacuole Periphery 0.36 -17.21 -7.50 -13.67 13.38 3.65 -8.56 -0.85 -3.88 7.02 3.39 -24.29 -11.05 -14.50 13.47
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has a calmodulin-binding motif and binds calmodulin in vitro; INH1 has a paralog, STF1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (76%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Inh1

Inh1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Inh1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available