Standard name
Human Ortholog
Description ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; ARF1 has a paralog, ARF2, that arose from the whole genome duplication; arf1 arf2 double null mutation is complemented by human ARF1, ARF4, ARF5, or ARF6
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.12 0.07 0.07 0.09 0.18 0.19 0.22 0.18 0.19 0.24 0.09 0.05 0.05 0 0 0 0.1 0.17 0.11 0.07 0.09 0.08
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.11 0.26 0.12 0.16 0.21 0.32 0.24 0.24 0.22 0.33 0.33 0.37 0.12 0.05 0.07 0.27 0.28 0.22 0.05 0.07 0 0 0 0
Endoplasmic Reticulum 0.4 0.39 0.17 0.16 0.22 0.34 0.36 0.36 0.32 0.26 0.24 0.28 0.23 0.18 0.21 0.13 0.09 0.1 0.05 0.07 0 0.07 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0
Golgi 0.42 0.35 0.71 0.74 0.54 0.24 0.27 0.27 0.31 0.31 0.27 0.23 0.66 0.76 0.7 0.51 0.53 0.63 0.64 0.48 0.76 0.74 0.76 0.72
Mitochondria 0 0 0.17 0 0 0 0 0 0 0 0.05 0 0 0 0 0.17 0.19 0.11 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.12 0 0.07 0.05 0 0.06 0 0.06 0.07 0 0.06 0.07 0 0 0 0.11 0.06 0.06 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 2 5 8 10 11 39 51 46 33 25 47 11 11 14 0 3 2 16 41 8 8 16 19
Bud 1 5 1 3 4 2 9 12 6 7 6 6 2 2 4 2 2 1 2 3 1 2 1 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 1 0 0 1 0 5 5 1 2 3 4 1 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 11 32 5 18 29 40 51 65 45 59 43 72 15 12 20 35 33 26 8 15 2 0 2 5
Endoplasmic Reticulum 39 49 7 18 31 42 77 95 66 47 31 54 30 41 59 17 11 12 8 16 1 8 6 8
Endosome 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 8 18 1 5 8 9
Golgi 41 44 29 85 76 30 57 73 64 56 35 45 84 178 193 65 63 75 104 117 54 93 151 182
Mitochondria 0 0 7 1 3 5 9 3 9 2 6 7 1 1 0 22 23 13 1 2 0 1 2 1
Nucleus 0 0 0 0 0 0 1 1 0 0 1 0 0 0 1 0 0 0 0 2 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 12 1 3 6 6 7 6 16 14 4 8 14 3 5 6 14 7 7 1 0 0 0 1 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 2
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Vac/Vac Membrane 0 3 0 0 1 1 1 2 4 7 0 4 4 6 5 5 6 3 4 11 0 2 2 6
Unique Cell Count 97 125 41 115 140 124 213 267 205 179 130 196 128 233 275 128 119 119 162 243 72 126 198 253
Labelled Cell Count 109 137 57 139 161 138 256 323 255 217 158 254 151 256 303 160 148 139 162 243 72 126 198 253


Early Golgi, Late Golgi, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 73.4 80.7 54.5 50.0 47.4 40.8 38.8 39.7 37.9 37.1 36.0 35.9 64.7 65.8 67.7 80.1 83.3 84.5 76.0 76.0 76.4
Std Deviation (1e-4) 15.5 14.7 12.5 14.6 11.3 12.1 10.2 10.5 10.3 10.1 9.6 8.4 15.4 15.4 15.2 24.6 27.4 22.6 17.7 18.5 22.7
Intensity Change (Log2) – – – -0.12 -0.2 -0.42 -0.49 -0.46 -0.52 -0.56 -0.6 -0.6 0.25 0.27 0.31 0.56 0.61 0.63 0.48 0.48 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100WT3HU80HU120HU160050100WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100WT1AF100AF140AF180050100
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0.9 1.1 1.5 1.0 1.0 1.7 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.5 1.2 2.5 1.7 1.7 1.4 2.6 2.6 3.1 0 0 0 2.0 2.0 1.3
Endoplasmic Reticulum -0.2 0.7 2.0 2.4 2.3 1.9 1.2 0.9 1.4 0.9 0.1 0.6 -0.6 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.4 -1.9 -5.4 -5.4 -5.5 -4.8 -4.7 -5.1 -6.0 -0.6 0.8 -0.1 -2.2 -2.0 -0.9
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0.3 -1.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 64.9031 82.653 76.1146 71.9429 61.5911 76.9498 60.3458 82.1146 79.7066 62.9625 58.8041 78.3149 82.2309 95.0883 89.6803 84.5903 81.9453 89.6754
Actin 0.1124 0.0485 0.0392 0.0585 0.037 0.0622 0.0635 0.099 0.1023 0.0048 0.0144 0.0482 0.0541 0.0564 0.0313 0.0032 0.0045 0.0231
Bud 0.0021 0.0017 0.0019 0.0009 0.0019 0.0005 0.0024 0.0012 0.0007 0.0011 0.0019 0.0002 0.0004 0.0012 0.0006 0 0.0002 0.0002
Bud Neck 0.0051 0.0029 0.0018 0.0024 0.0016 0.0048 0.0015 0.0024 0.0015 0.0006 0.002 0.001 0.0009 0.0022 0.0016 0.0002 0.0005 0.0008
Bud Periphery 0.0026 0.0019 0.0024 0.0026 0.0022 0.0008 0.0028 0.0011 0.0009 0.0012 0.0027 0.0004 0.0005 0.0012 0.0011 0.0001 0.0005 0.0003
Bud Site 0.0092 0.0109 0.0111 0.0011 0.0021 0.0005 0.0052 0.0055 0.0025 0.0036 0.0047 0.0002 0.001 0.0062 0.002 0.0001 0.0002 0.0006
Cell Periphery 0.0105 0.0102 0.0088 0.0099 0.0093 0.0036 0.007 0.0072 0.0125 0.0024 0.0034 0.0033 0.0052 0.0084 0.0081 0.002 0.0035 0.0014
Cytoplasm 0.0082 0.0039 0.0042 0.0008 0.0047 0.0006 0.0107 0.0103 0.0073 0.0299 0.0019 0.0006 0.0008 0.0026 0.0011 0.0004 0.0006 0.0002
Cytoplasmic Foci 0.0456 0.0393 0.0354 0.0131 0.0918 0.0132 0.0472 0.0302 0.0229 0.067 0.0327 0.0122 0.0217 0.0297 0.0172 0.0213 0.017 0.0106
Eisosomes 0.005 0.0013 0.0012 0.0019 0.0007 0.0018 0.0015 0.0008 0.0023 0.0002 0.0003 0.0009 0.0023 0.0012 0.0034 0.0004 0.0003 0.0008
Endoplasmic Reticulum 0.0147 0.0007 0.0063 0.0009 0.0012 0.0007 0.0125 0.0007 0.0032 0.0115 0.0005 0.0006 0.0005 0.0005 0.0005 0.0007 0.0007 0.0004
Endosome 0.0796 0.1058 0.0739 0.0733 0.1199 0.0475 0.0791 0.0862 0.0533 0.0612 0.0792 0.0629 0.0568 0.0779 0.0645 0.0741 0.0875 0.0409
Golgi 0.3814 0.4136 0.4511 0.4933 0.4021 0.6693 0.3711 0.4913 0.4589 0.3602 0.5853 0.6782 0.4598 0.4405 0.4829 0.4084 0.5946 0.6679
Lipid Particles 0.1435 0.2085 0.2233 0.1572 0.1831 0.1344 0.1852 0.1379 0.1791 0.3374 0.0662 0.0871 0.1744 0.1613 0.2211 0.3775 0.1851 0.1804
Mitochondria 0.0866 0.0485 0.0439 0.043 0.0385 0.0342 0.067 0.0397 0.0656 0.0375 0.1577 0.0626 0.1333 0.0994 0.0609 0.0276 0.038 0.05
None 0.0049 0.0002 0.001 0.0001 0.0051 0.0001 0.0057 0.0001 0.0019 0.0024 0.0001 0.0001 0.0003 0.0002 0.0001 0 0.0001 0
Nuclear Periphery 0.0064 0.0007 0.0017 0.0012 0.0008 0.0006 0.0075 0.0008 0.0015 0.006 0.0007 0.0005 0.0011 0.0012 0.0005 0.0005 0.015 0.0002
Nucleolus 0.017 0.0255 0.0201 0.0013 0.028 0.0016 0.0517 0.0334 0.0083 0.0184 0.0119 0.0013 0.036 0.0372 0.0242 0.0051 0.0038 0.0058
Nucleus 0.0028 0.0029 0.0042 0.0006 0.002 0.0004 0.0054 0.0032 0.0015 0.0025 0.0012 0.0002 0.0029 0.0042 0.0023 0.0004 0.0024 0.0003
Peroxisomes 0.0091 0.004 0.0053 0.0026 0.0039 0.0048 0.0096 0.006 0.0036 0.0102 0.0122 0.0011 0.0052 0.0067 0.0035 0.0027 0.0008 0.0015
Punctate Nuclear 0.0013 0.0004 0.0006 0.0001 0.0011 0.0001 0.0115 0.0002 0.0007 0.0034 0.0002 0.0001 0.0007 0.0005 0.0001 0.0001 0.0004 0.0001
Vacuole 0.0273 0.0387 0.0256 0.054 0.0283 0.0066 0.0215 0.0211 0.0237 0.0141 0.0107 0.0103 0.015 0.0234 0.0295 0.0482 0.0125 0.0025
Vacuole Periphery 0.0248 0.0298 0.0372 0.0813 0.0348 0.0115 0.0305 0.0219 0.0457 0.0244 0.01 0.028 0.0271 0.0379 0.0434 0.027 0.0317 0.0118

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 772.9894 760.5575 837.8362 767.2678 817.4926 731.1562 828.82 793.944 845.2746 757.4551
Translational Efficiency 1.3201 1.4058 1.2205 1.7461 1.3532 1.3769 1.4316 1.7049 1.2722 1.3206

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
855 1168 1351 1429 1541 1588 2707 1633 2396 2756 4058 3062

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3369.78 4176.64 6708.19 7788.65 3882.21 4688.81 7948.45 7485.37 3699.35 4471.75 7535.54 7626.91
Standard Deviation 667.83 1240.55 1141.99 1668.94 913.89 940.35 1415.32 1741.70 869.81 1107.15 1453.29 1714.82
Intensity Change Log 2 — 0.309688 0.993269 1.208719 — 0.272344 1.033795 0.947195 — 0.289817 1.015106 1.074631

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.007399 0.027569 0.008260 0.021580 0.012089 0.009976 0.006613 0.011229 0.010415 0.017432 0.007162 0.016060
Bud Neck 0.008688 0.009907 0.012922 0.004891 0.004749 0.010119 0.002875 0.004128 0.006155 0.010029 0.006220 0.004484
Bud Site 0.022112 0.014895 0.006495 0.032166 0.007317 0.018327 0.007772 0.022614 0.012597 0.016873 0.007347 0.027072
Cell Periphery 0.002395 0.001827 0.001014 0.004888 0.001723 0.001773 0.001028 0.002932 0.001963 0.001796 0.001023 0.003845
Cytoplasm 0.001188 0.003184 0.000504 0.006815 0.000706 0.002127 0.000983 0.005358 0.000878 0.002575 0.000824 0.006038
Cytoplasmic Foci 0.046117 0.051023 0.051619 0.035718 0.028627 0.062423 0.021089 0.032407 0.034868 0.057592 0.031253 0.033952
Eisosomes 0.000188 0.000715 0.000203 0.000305 0.000366 0.000233 0.000113 0.000169 0.000302 0.000437 0.000143 0.000233
Endoplasmic Reticulum 0.003072 0.003463 0.000794 0.003618 0.004264 0.002070 0.001051 0.002268 0.003839 0.002660 0.000966 0.002898
Endosome 0.058926 0.055186 0.029187 0.065274 0.045060 0.068670 0.069060 0.061195 0.050008 0.062955 0.055786 0.063098
Golgi 0.591325 0.498866 0.456505 0.570019 0.624681 0.537020 0.657761 0.631290 0.612778 0.520850 0.590759 0.602696
Lipid Particles 0.049872 0.157381 0.108059 0.083477 0.131004 0.066147 0.032536 0.072239 0.102052 0.104812 0.057679 0.077484
Mitochondria 0.024370 0.045849 0.036670 0.009291 0.021725 0.052052 0.051535 0.006997 0.022669 0.049423 0.046586 0.008068
Mitotic Spindle 0.003869 0.002396 0.006026 0.005081 0.001006 0.004071 0.002314 0.005990 0.002028 0.003361 0.003549 0.005565
None 0.000464 0.002470 0.000669 0.000498 0.000561 0.000736 0.000449 0.000526 0.000527 0.001471 0.000522 0.000513
Nuclear Periphery 0.000733 0.000689 0.006103 0.000481 0.000602 0.001168 0.000817 0.000580 0.000649 0.000965 0.002577 0.000534
Nuclear Periphery Foci 0.003694 0.003283 0.006373 0.002904 0.002718 0.003548 0.001583 0.002516 0.003066 0.003435 0.003178 0.002697
Nucleolus 0.000723 0.001826 0.001172 0.000173 0.000371 0.000935 0.000208 0.000234 0.000497 0.001313 0.000529 0.000205
Nucleus 0.001714 0.001374 0.000207 0.000270 0.000155 0.000400 0.000086 0.000589 0.000711 0.000813 0.000126 0.000440
Peroxisomes 0.000697 0.002100 0.000698 0.000576 0.000470 0.001512 0.000294 0.000489 0.000551 0.001761 0.000429 0.000530
Vacuole 0.100167 0.068829 0.132025 0.121362 0.061206 0.097591 0.073383 0.101597 0.075109 0.085402 0.092906 0.110821
Vacuole Periphery 0.072289 0.047168 0.134495 0.030612 0.050599 0.059101 0.068451 0.034653 0.058339 0.054044 0.090439 0.032767

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.80 -0.59 -5.94 1.78 -5.74 1.37 4.00 0.46 -0.89 -3.43 -4.90 3.12 -4.07 0.69 -6.85
Bud Neck -0.97 -3.84 4.11 5.26 8.43 -6.91 3.29 0.25 7.35 -3.34 -6.05 -0.54 2.74 8.99 3.53
Bud Site 3.00 7.25 -4.19 -7.89 -12.89 -7.85 -0.80 -9.36 -3.04 -9.17 -3.37 5.34 -10.47 -7.61 -15.42
Cell Periphery 2.64 7.36 -7.09 -9.22 -12.19 -0.41 4.22 -4.54 -4.16 -7.15 1.08 7.49 -8.67 -9.44 -13.50
Cytoplasm -3.06 5.09 -7.37 -4.00 -8.26 -2.89 -2.25 -5.97 -3.49 -5.63 -4.25 0.47 -9.36 -5.29 -9.41
Cytoplasmic Foci -1.11 -1.32 2.41 4.23 4.18 -10.47 4.20 -2.64 8.57 -7.03 -8.98 1.64 -0.41 9.37 -2.35
Eisosomes -6.22 -0.57 -2.69 4.65 -2.57 3.54 7.87 5.62 2.43 -2.98 -3.16 6.83 2.46 5.00 -4.34
Endoplasmic Reticulum -0.74 6.02 -1.00 -0.29 -9.35 4.58 7.32 4.14 -0.55 -4.99 3.35 9.18 2.73 -0.82 -9.97
Endosome 1.15 10.33 -1.59 -2.99 -14.09 -8.63 -9.51 -6.20 2.64 2.93 -6.04 -2.84 -6.16 0.16 -3.43
Golgi 6.23 9.61 2.47 -4.38 -8.20 8.07 -3.22 0.71 -7.24 3.94 10.49 2.93 2.80 -8.05 0.06
Lipid Particles -13.32 -8.68 -5.81 8.94 3.43 9.92 16.84 8.63 -1.27 -9.15 -0.51 9.79 4.81 5.61 -5.70
Mitochondria -4.35 -3.05 4.60 8.32 8.22 -6.84 -8.48 6.07 11.38 15.33 -8.10 -8.85 7.39 14.00 17.01
Mitotic Spindle 2.19 -2.64 -2.05 -3.56 0.42 -5.57 -2.78 -5.29 -2.23 -3.94 -3.20 -3.66 -5.96 -3.77 -3.50
None -2.92 -3.62 -0.87 2.62 0.26 -0.74 0.63 -0.23 0.55 -0.67 -2.93 0.05 -0.70 2.57 -0.54
Nuclear Periphery 0.64 -10.25 3.25 2.99 10.76 -3.33 -1.98 -0.16 3.54 2.30 -2.96 -9.97 1.20 4.30 10.81
Nuclear Periphery Foci 0.64 -4.16 1.36 0.37 6.06 -1.93 2.92 0.14 2.50 -3.92 -1.03 -0.44 0.71 1.90 1.43
Nucleolus -2.37 -1.39 2.18 4.48 4.39 -2.88 1.36 0.95 3.29 -0.45 -3.77 -0.44 2.47 5.58 3.19
Nucleus 0.29 1.30 1.19 2.46 -1.29 -1.84 1.38 -2.62 -1.24 -2.85 -0.24 1.40 0.33 1.10 -3.26
Peroxisomes -4.97 -0.18 1.04 5.57 1.34 -7.26 3.26 -0.38 7.06 -3.66 -8.37 2.05 0.24 8.61 -2.07
Vacuole 5.13 -4.99 -3.86 -9.77 0.76 -8.13 -3.45 -8.95 -1.63 -6.61 -2.94 -5.45 -9.98 -7.58 -5.87
Vacuole Periphery 5.64 -11.49 10.38 6.47 25.83 -2.74 -6.30 6.34 9.18 13.95 1.75 -11.94 11.93 11.37 27.24
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; ARF1 has a paralog, ARF2, that arose from the whole genome duplication; arf1 arf2 double null mutation is complemented by human ARF1, ARF4, ARF5, or ARF6
Localization
Cell Percentages cytoplasm (14%), nucleus (1%), mixed (46%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Arf1

Arf1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Arf1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available