Standard name
Human Ortholog
Description D-Tyr-tRNA(Tyr) deacylase; functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Cytoplasm 0.89 0.89 0.91 0.92 0.85 0.82 0.78 – 0.65 0.65 0.62 0.54 0.98 0.98 0.97 0.96 0.96 0.94 0.73 0.68 0.63 0.75 0.73 0.66
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0.06 0 0 – 0 0 0.05 0 0 0 0 0 0 0 0.08 0.08 0 0.06 0.05 0.06
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.15 0 0.05 0 0.28 0.11 – 0.34 0.3 0.36 0.46 0 0 0 0 0 0 0.05 0.14 0.24 0.11 0.09 0.14
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.1 0 0.16 – 0.14 0.06 0.08 0.09 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 1 0 2 0 0 – 0 1 0 1 3 1 2 0 1 0 2 2 1 1 8 15
Bud 0 4 0 2 1 6 1 – 1 5 6 9 1 1 1 0 0 0 1 0 0 0 6 3
Bud Neck 0 0 1 1 0 0 1 – 0 0 0 0 0 0 0 0 1 0 2 1 0 0 7 8
Bud Site 0 0 0 0 0 0 0 – 0 0 2 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 2 12 4 0 4 – 1 2 6 2 6 5 2 12 13 13 0 0 0 0 1 2
Cytoplasm 141 106 135 288 384 204 327 – 189 174 163 158 292 506 551 219 279 261 129 89 113 130 398 301
Endoplasmic Reticulum 2 1 3 0 2 1 1 – 0 1 1 2 3 2 3 9 11 10 2 0 1 1 8 5
Endosome 5 0 3 3 25 4 18 – 5 9 12 7 1 6 13 0 2 4 13 10 6 9 27 26
Golgi 2 1 0 1 2 0 0 – 0 0 0 0 0 1 0 0 0 1 3 0 0 0 1 0
Mitochondria 6 18 2 17 14 70 44 – 100 81 95 135 1 1 1 2 5 4 9 18 42 18 49 64
Nucleus 0 0 1 0 2 4 0 – 7 3 6 7 0 0 0 9 3 6 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 0 1 1 – 0 2 0 1 0 0 0 0 0 0 0 0 0 0 2 0
Nucleolus 0 0 0 0 0 0 0 – 0 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 3 0 0 – 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 3 4 3 0 7 – 3 4 5 6 0 0 1 0 0 0 2 1 3 3 14 11
Vac/Vac Membrane 3 2 3 11 47 9 66 – 41 17 22 26 1 0 4 1 3 5 6 5 2 2 7 6
Unique Cell Count 159 119 148 312 453 249 417 290 269 263 291 297 515 567 229 290 279 178 132 180 173 546 457
Labelled Cell Count 161 132 154 339 489 299 470 347 301 320 355 308 524 578 252 318 305 178 132 180 173 546 457


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 4.9 5.8 6.3 6.8 4.7 5.7 – 5.1 5.1 5.2 4.8 6.6 6.5 6.7 6.8 7.3 7.3 5.4 5.5 5.6
Std Deviation (1e-4) 1.2 0.9 1.1 2.5 1.7 1.4 1.6 – 1.6 1.1 1.7 0.9 1.1 1.0 1.3 1.0 1.2 1.4 0.8 1.0 1.2
Intensity Change (Log2) – – – 0.12 0.22 -0.31 -0.02 – -0.18 -0.19 -0.16 -0.27 0.19 0.16 0.21 0.22 0.33 0.32 -0.1 -0.08 -0.06


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0508 1.9716 1.41 1.5769 1.1102 1.4947 2.2204 3.7901 3.6271 2.9599 2.2022 3.5496 4.6159 6.2958 5.7842 4.8252 5.1372 5.368
Actin 0.011 0.0006 0.0082 0.0002 0.0273 0.0014 0.0122 0.0007 0.0073 0.0019 0.0017 0.0005 0.0328 0.0002 0.013 0.0823 0.0234 0.0025
Bud 0.0004 0.0002 0.0009 0.0006 0.0006 0.0002 0.0006 0.0005 0.0008 0.0011 0.0003 0.0006 0.0033 0.0001 0.001 0.0006 0.0002 0.001
Bud Neck 0.0024 0.0002 0.0009 0.0003 0.0025 0.0013 0.0023 0.0005 0.001 0.0009 0.0009 0.0032 0.0015 0.0001 0.0003 0.0005 0.0005 0.0008
Bud Periphery 0.0003 0.0001 0.0005 0.0001 0.0005 0.0001 0.0005 0.0002 0.0005 0.0006 0.0002 0.0007 0.0017 0 0.0009 0.0006 0.0003 0.0007
Bud Site 0.0017 0.0016 0.0048 0.0002 0.0028 0.0002 0.004 0.0037 0.0052 0.0006 0.0007 0.0005 0.0042 0.0005 0.001 0.0026 0.0003 0.0001
Cell Periphery 0.0002 0.0002 0.0002 0.0001 0.0002 0.0001 0.0003 0.0002 0.0002 0.0001 0 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.7297 0.8211 0.7914 0.8144 0.7603 0.8343 0.7978 0.8986 0.8945 0.9008 0.8673 0.8804 0.7357 0.9146 0.8392 0.7652 0.7908 0.8779
Cytoplasmic Foci 0.0431 0.0154 0.0351 0.0179 0.0621 0.0386 0.0301 0.0257 0.0254 0.019 0.0348 0.0262 0.0496 0.0081 0.0182 0.0205 0.0144 0.0225
Eisosomes 0.0003 0 0.0001 0 0.0003 0 0.0001 0 0.0004 0 0 0 0.0003 0 0.0001 0.0006 0.0011 0
Endoplasmic Reticulum 0.0112 0.0026 0.0096 0.014 0.0038 0.0049 0.0165 0.0038 0.0046 0.0142 0.006 0.005 0.0109 0.0033 0.0043 0.0014 0.0026 0.0084
Endosome 0.0353 0.0109 0.0365 0.0369 0.0451 0.0354 0.0559 0.0306 0.0215 0.0412 0.0523 0.0352 0.0304 0.0124 0.0102 0.0105 0.0138 0.0217
Golgi 0.005 0.0011 0.0067 0.001 0.0087 0.0031 0.0064 0.0044 0.0021 0.0021 0.0111 0.0017 0.0055 0.0006 0.0021 0.0065 0.004 0.0046
Lipid Particles 0.0025 0.0006 0.0013 0.0001 0.0198 0.0004 0.0021 0.0001 0.0014 0.0004 0.0006 0.0001 0.003 0.0002 0.0009 0.0048 0.0121 0.0023
Mitochondria 0.001 0.0006 0.0021 0.001 0.0022 0.0017 0.0018 0.0026 0.0019 0.0011 0.0072 0.0096 0.0026 0.0002 0.0009 0.0115 0.0034 0.0058
None 0.1336 0.1375 0.0944 0.1057 0.0472 0.0724 0.0425 0.0221 0.0238 0.0034 0.0053 0.0271 0.0878 0.0564 0.1006 0.0564 0.1032 0.0439
Nuclear Periphery 0.0045 0.0008 0.0014 0.0014 0.0014 0.0009 0.0068 0.0007 0.0012 0.0047 0.0025 0.001 0.0051 0.0004 0.0009 0.0007 0.0107 0.0024
Nucleolus 0.0003 0.0001 0.0001 0.0001 0.0001 0 0.004 0 0.0001 0 0 0.0001 0.0003 0 0.0001 0.0001 0.0008 0.0001
Nucleus 0.0034 0.0025 0.0011 0.0012 0.0015 0.0016 0.0056 0.0012 0.0024 0.0027 0.0027 0.0029 0.0024 0.0007 0.001 0.0011 0.0018 0.0011
Peroxisomes 0.0043 0.0001 0.0011 0.0001 0.0081 0.0004 0.001 0.0003 0.0006 0.0003 0.0024 0.0004 0.0046 0 0.0033 0.0318 0.0116 0.0019
Punctate Nuclear 0.005 0.0007 0.001 0.0002 0.0013 0.0006 0.0016 0.0003 0.0011 0.0007 0.0006 0.0008 0.0153 0.0001 0.0005 0.0009 0.0026 0.0011
Vacuole 0.0041 0.0028 0.002 0.0032 0.0032 0.002 0.0063 0.0029 0.0034 0.0031 0.0022 0.0028 0.0021 0.0018 0.0009 0.0007 0.001 0.0009
Vacuole Periphery 0.0007 0.0004 0.0005 0.0012 0.0011 0.0006 0.0017 0.0007 0.0006 0.0008 0.001 0.0011 0.0006 0.0002 0.0002 0.0005 0.0014 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 63.3301 39.1938 37.1622 35.232 60.0036 63.295 34.1248 25.2608 35.6796 56.5905
Translational Efficiency 1.4342 1.6106 1.1212 1.651 1.3462 1.4333 2.0822 2.0151 1.6059 1.812

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1882 363 1628 157 1645 1937 266 1927 3527 2300 1894 2084

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 729.07 783.09 963.35 1014.67 746.68 827.54 1066.65 931.69 737.28 820.52 977.86 937.94
Standard Deviation 91.68 148.64 110.86 105.09 87.93 97.24 106.31 119.02 90.38 108.23 115.93 120.04
Intensity Change Log 2 — 0.103121 0.402003 0.476881 — 0.148339 0.514525 0.319360 — 0.126177 0.460031 0.399330

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000389 0.000834 0.000166 0.001322 0.000098 0.000239 0.000571 0.000745 0.000254 0.000333 0.000223 0.000789
Bud Neck 0.024926 0.022139 0.001974 0.003756 0.005167 0.046983 0.001880 0.013807 0.015710 0.043062 0.001960 0.013050
Bud Site 0.015945 0.040409 0.008878 0.020607 0.004339 0.024528 0.012282 0.037070 0.010532 0.027034 0.009356 0.035830
Cell Periphery 0.000162 0.000207 0.000080 0.000118 0.000110 0.000135 0.000194 0.000084 0.000138 0.000146 0.000096 0.000087
Cytoplasm 0.374887* 0.382649* 0.645946* 0.484569* 0.610533* 0.334701* 0.539250* 0.510774* 0.484793* 0.342269* 0.630961* 0.508800*
Cytoplasmic Foci 0.350902* 0.287279* 0.016200 0.074498 0.186868* 0.252175* 0.031761 0.096796 0.274396* 0.257715* 0.018385 0.095116
Eisosomes 0.000266 0.000111 0.000020 0.000063 0.000064 0.000106 0.000063 0.000035 0.000172 0.000107 0.000026 0.000037
Endoplasmic Reticulum 0.002106 0.001012 0.001735 0.002413 0.001181 0.001409 0.003960 0.000933 0.001675 0.001346 0.002048 0.001044
Endosome 0.029979 0.053776 0.002407 0.008140 0.009615 0.059903 0.007246 0.020163 0.020481 0.058936 0.003086 0.019258
Golgi 0.012516 0.012568 0.000117 0.002003 0.002444 0.011142 0.000195 0.003487 0.007819 0.011367 0.000128 0.003375
Lipid Particles 0.013358 0.005722 0.000861 0.002168 0.005104 0.006984 0.002534 0.001838 0.009508 0.006785 0.001096 0.001863
Mitochondria 0.017051 0.006833 0.000446 0.003768 0.002809 0.017969 0.000269 0.001674 0.010408 0.016212 0.000422 0.001832
Mitotic Spindle 0.002496 0.002737 0.010659 0.010378 0.001078 0.005352 0.008136 0.036495 0.001835 0.004939 0.010305 0.034527
None 0.001666 0.004445 0.003619 0.002860 0.003528 0.002202 0.002369 0.001538 0.002534 0.002556 0.003443 0.001637
Nuclear Periphery 0.000283 0.000212 0.001151 0.001718 0.000432 0.000411 0.001130 0.000601 0.000352 0.000379 0.001148 0.000685
Nuclear Periphery Foci 0.000368 0.001317 0.001992 0.005784 0.000535 0.000333 0.010222 0.001215 0.000446 0.000488 0.003148 0.001560
Nucleolus 0.001259 0.004491 0.000215 0.000230 0.001074 0.002396 0.000208 0.001183 0.001173 0.002727 0.000214 0.001111
Nucleus 0.065648 0.035318 0.227793* 0.064521 0.123899 0.064912 0.170397* 0.052175 0.092817 0.060242 0.219732* 0.053105
Peroxisomes 0.008947 0.019753 0.000396 0.003123 0.001902 0.010416 0.000478 0.006869 0.005661 0.011890 0.000408 0.006586
Vacuole 0.072904 0.112819 0.075114 0.304261* 0.037511 0.149382 0.206566* 0.209335* 0.056397 0.143612 0.093576 0.216487*
Vacuole Periphery 0.003941 0.005371 0.000231 0.003701 0.001710 0.008319 0.000289 0.003181 0.002900 0.007854 0.000239 0.003220

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.04 1.63 -2.22 -0.50 -2.73 -4.25 -8.53 -4.27 -3.00 0.05 -1.66 -0.98 -3.28 -2.60 -2.69
Bud Neck 1.11 17.52 15.33 6.54 -2.62 -17.80 5.26 -8.04 13.94 -12.40 -12.85 17.74 3.25 14.41 -12.63
Bud Site -5.78 4.78 1.28 5.96 -1.99 -12.75 -2.38 -12.88 -1.48 -4.96 -10.47 1.84 -9.17 0.08 -9.35
Cell Periphery -1.08 8.01 4.64 2.61 -1.78 -2.02 -4.55 6.46 5.74 7.05 -0.60 5.91 9.76 6.45 4.72
Cytoplasm -0.45 -21.80 0.45 0.65 8.59 31.21 9.72 13.69 -16.47 -2.38 18.98 -8.74 0.96 -15.55 8.50
Cytoplasmic Foci 5.47 62.63 35.55 18.27 -5.66 -9.56 30.89 19.64 30.32 -14.98 2.93 66.02 42.27 34.33 -22.10
Eisosomes 5.75 9.50 7.83 4.25 -7.64 -4.97 -0.06 9.57 9.27 6.94 4.24 10.24 10.03 10.45 -1.80
Endoplasmic Reticulum 4.07 -1.22 -1.38 -5.28 -0.60 -0.90 -8.68 2.04 2.30 9.95 1.46 -5.65 4.23 1.66 13.29
Endosome -4.97 20.19 16.20 10.58 -4.00 -21.45 4.60 -4.81 18.50 -8.67 -17.60 21.55 5.39 20.34 -13.33
Golgi 0.15 14.05 11.77 5.21 -1.22 -10.24 5.87 0.42 10.10 -4.36 -3.92 15.06 8.60 10.99 -4.57
Lipid Particles 5.96 13.02 11.18 3.79 -5.31 -2.86 5.99 7.73 9.65 2.42 3.79 15.20 13.69 10.38 -2.95
Mitochondria 4.84 10.89 8.91 3.03 -0.93 -11.54 5.34 2.74 13.40 -7.41 -4.23 11.72 10.38 13.75 -6.08
Mitotic Spindle -0.27 -4.37 -1.79 -1.72 0.08 -4.54 -1.38 -10.89 -8.94 -5.78 -3.64 -5.05 -10.71 -9.22 -6.58
None -2.48 -5.74 -0.50 2.06 2.49 2.99 1.67 6.50 1.80 2.88 -0.03 -2.76 4.41 2.69 7.24
Nuclear Periphery 1.50 -20.10 -5.43 -5.65 -0.25 0.27 -10.07 -5.62 -6.92 6.48 -0.54 -19.68 -10.29 -8.89 9.44
Nuclear Periphery Foci -5.36 -12.61 -7.56 -5.52 -3.94 3.24 -10.59 -4.72 -6.33 9.83 -1.26 -15.50 -7.95 -7.01 9.11
Nucleolus -1.97 5.00 4.65 2.57 -0.87 -3.96 4.60 -0.65 3.16 -4.49 -4.14 6.71 -0.04 3.79 -4.43
Nucleus 6.25 -31.82 -2.71 -5.74 17.11 14.01 -6.97 14.73 0.03 12.09 10.67 -28.75 8.88 -2.00 33.30
Peroxisomes -4.10 13.20 8.99 7.00 -2.71 -13.97 7.11 -6.31 7.42 -10.42 -8.64 14.20 1.52 9.40 -10.39
Vacuole -5.26 -9.77 -15.24 -12.75 -13.08 -25.26 -15.26 -38.61 -16.12 0.68 -21.72 -18.33 -37.74 -19.48 -18.45
Vacuole Periphery -1.61 13.93 2.61 3.18 -0.97 -11.49 7.31 -0.70 8.81 -3.99 -9.87 15.43 1.94 9.11 -4.12
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description D-Tyr-tRNA(Tyr) deacylase; functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes
Localization
Cell Percentages cytoplasm (67%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Dtd1

Dtd1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dtd1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available