Standard name
Human Ortholog
Description Integral membrane protein localized to mitochondria; required for sporulation and maintaining sphingolipid content; similar to SUR7; FMP45 has a paralog, YNL194C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – 0 0 0 0 0 0 0 0.05 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 – 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0.06 0.05 0 0 0
Bud Neck 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 – 0 0 0 0 0 0 0 0.05 0.05 0.09 0 0 0 0.08 0.05 0.06 0 0.14 0.06 0 0 0
Cytoplasm 0.88 – 0.93 0.92 0.97 0.95 0.92 0.89 0.8 0.8 0.62 0.66 0.96 0.96 0.94 0.85 0.82 0.86 0.61 0.59 0.56 0.79 0.78 0.77
Endoplasmic Reticulum 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0.09 0 0 0 0 0 0
Endosome 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.19 – 0 0 0 0.05 0.11 0.09 0.23 0.18 0.44 0.27 0 0 0 0 0 0 0.22 0.06 0.16 0.05 0.06 0.06
Nucleus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 0 0 0.07 0.05 0 0 0 0 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0.05 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 – 2 3 1 3 2 10 14 16 9 25 5 5 14 3 2 1 3 1 6 2 7 5
Bud 0 – 2 2 0 3 5 9 16 12 10 14 2 2 4 0 2 0 0 2 9 2 9 8
Bud Neck 0 – 4 2 13 12 18 15 12 16 3 8 6 1 2 1 2 1 0 0 3 0 3 4
Bud Site 0 – 0 0 1 0 0 0 1 1 4 2 0 1 0 0 0 0 – – – – – –
Cell Periphery 0 – 4 4 3 3 3 7 12 16 11 22 7 11 14 13 8 10 2 5 12 6 8 15
Cytoplasm 129 – 197 197 344 328 491 457 305 246 134 162 275 467 474 140 141 136 105 22 114 117 288 326
Endoplasmic Reticulum 0 – 1 1 0 0 1 1 2 1 1 3 1 0 4 9 12 14 1 1 4 1 3 2
Endosome 0 – 0 0 0 1 1 0 0 0 0 0 0 2 1 1 3 4 2 0 2 2 2 2
Golgi 0 – 0 1 1 0 0 0 0 3 0 2 1 0 3 0 3 1 0 0 1 1 1 1
Mitochondria 28 – 2 2 2 16 59 47 89 56 95 67 0 2 2 1 4 6 37 2 33 6 20 27
Nucleus 0 – 1 1 2 1 2 1 3 0 1 2 0 1 0 1 0 1 0 0 0 0 2 1
Nuclear Periphery 1 – 0 0 0 0 1 0 4 4 6 6 0 0 1 0 0 0 1 0 0 0 0 0
Nucleolus 0 – 0 0 1 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 1 1 2 1 4 0 1 4 0 0 2 0 0 0 0 0 0
SpindlePole 0 – 4 3 7 2 9 9 10 7 15 12 0 4 7 6 9 4 2 0 4 1 5 8
Vac/Vac Membrane 1 – 3 3 1 1 2 2 0 2 3 5 0 1 1 9 8 6 8 2 6 2 6 7
Unique Cell Count 146 211 213 353 347 534 511 381 306 217 246 285 485 506 164 171 159 173 38 206 150 370 426
Labelled Cell Count 160 220 219 376 370 595 559 469 382 293 336 297 498 531 184 194 186 173 38 206 150 370 426


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.0 – 5.2 5.2 4.6 3.7 3.3 3.8 3.6 3.9 4.1 4.5 4.6 5.2 5.0 6.0 6.4 6.2 4.5 4.8 5.2
Std Deviation (1e-4) 0.4 – 4.5 4.5 2.6 2.0 1.5 1.5 2.2 2.5 3.3 3.2 0.9 2.6 2.0 2.4 2.8 3.0 1.1 1.6 1.6
Intensity Change (Log2) – – – 0.0 -0.18 -0.51 -0.65 -0.45 -0.56 -0.43 -0.35 -0.23 -0.18 -0.02 -0.07 0.2 0.28 0.24 -0.22 -0.13 -0.02

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0.7 2.8 1.6 2.2
Cytoplasm -0.4 2.4 0.6 -0.7 -1.6 -4.3 -4.1 -7.8 -7.1 1.6 1.7 0.2 -2.5 -3.3 -2.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 3.5 4.0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 1.8 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 2.2 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1228 -0.4818 -0.2324 0.0627 -0.3831 -0.053 -1.0251 3.4144 0.1178 -1.1065 0.2485 0.8265 -1.3864 0.7025 1.2773 0.129 0.1467 1.0773
Actin 0.0693 0.0198 0.0246 0.0346 0.0795 0.0351 0.0571 0.0244 0.006 0.0019 0.0653 0.0415 0.0414 0.06 0.0577 0.0541 0.0573 0.0421
Bud 0.0072 0.0212 0.0156 0.0083 0.0076 0.0066 0.0075 0.0182 0.0066 0.0044 0.0006 0.0171 0.0052 0.021 0.01 0.0058 0.0193 0.0045
Bud Neck 0.0035 0.0032 0.0121 0.0149 0.0324 0.0217 0.0115 0.0036 0.0104 0.0031 0.0603 0.0196 0.0115 0.0066 0.0236 0.0141 0.0456 0.0358
Bud Periphery 0.0417 0.0238 0.0278 0.0311 0.04 0.0595 0.0451 0.0302 0.0204 0.0058 0.0026 0.0663 0.0213 0.0498 0.0427 0.033 0.0925 0.0582
Bud Site 0.0282 0.0957 0.0496 0.0332 0.0259 0.0031 0.0641 0.2056 0.0356 0.0575 0.0023 0.0154 0.0443 0.1947 0.0901 0.0403 0.012 0.0219
Cell Periphery 0.0258 0.0398 0.0577 0.0427 0.0708 0.057 0.0456 0.1125 0.1058 0.0269 0.0871 0.1518 0.0541 0.0772 0.1102 0.1327 0.094 0.2118
Cytoplasm 0.0636 0.0806 0.0958 0.1525 0.1374 0.1199 0.0362 0.0725 0.0868 0.0436 0.0807 0.0731 0.0574 0.0841 0.0854 0.128 0.0483 0.1335
Cytoplasmic Foci 0.0373 0.0118 0.0206 0.0164 0.0147 0.0257 0.0083 0.0033 0.0047 0.0119 0.0053 0.0053 0.0209 0.0078 0.0072 0.0179 0.0306 0.0042
Eisosomes 0.0248 0.0058 0.0148 0.0015 0.0051 0.0123 0.0095 0.0103 0.0163 0.0005 0.0312 0.0027 0.0158 0.0094 0.0238 0.0449 0.0237 0.0263
Endoplasmic Reticulum 0.0162 0.0016 0.0016 0.0071 0.0019 0.0021 0.0021 0.0006 0.0015 0.0007 0.0026 0.0016 0.0029 0.0051 0.0013 0.0016 0.0011 0.0018
Endosome 0.0325 0.0006 0.0094 0.0013 0.0421 0.012 0.007 0.0002 0.0023 0.0014 0.0185 0.0016 0.01 0.0004 0.0017 0.0108 0.0075 0.0005
Golgi 0.0145 0.0005 0.0076 0.001 0.019 0.0056 0.0024 0.0002 0.0004 0.0004 0.0084 0.0016 0.0054 0.001 0.0033 0.0096 0.0114 0.0004
Lipid Particles 0.0158 0.0007 0.0047 0.0019 0.0216 0.0141 0.0036 0.0006 0.0007 0.0013 0.0046 0.0004 0.0161 0.0008 0.0047 0.0493 0.0348 0.0007
Mitochondria 0.0283 0.0018 0.0142 0.0036 0.0129 0.0067 0.0112 0.0006 0.0018 0.0019 0.0068 0.0011 0.0029 0.0017 0.0133 0.0545 0.0066 0.0024
None 0.5198 0.6809 0.6238 0.6094 0.4723 0.5954 0.6714 0.5144 0.6786 0.8136 0.6032 0.5952 0.668 0.4762 0.5134 0.3714 0.441 0.4523
Nuclear Periphery 0.014 0.0008 0.0017 0.0041 0.0028 0.0025 0.0026 0.0002 0.0058 0.0012 0.012 0.0004 0.0014 0.0006 0.0003 0.0007 0.0005 0.0002
Nucleolus 0.0039 0.0007 0.001 0.0019 0.0003 0.001 0.0064 0.0004 0.0006 0.0012 0.0004 0.0005 0.0006 0.0003 0.0005 0.0009 0.0011 0.0002
Nucleus 0.0104 0.0043 0.0045 0.0055 0.0009 0.0057 0.0014 0.0005 0.0014 0.0025 0.0015 0.001 0.0013 0.0006 0.0006 0.0007 0.0006 0.0004
Peroxisomes 0.0223 0.0018 0.0084 0.0057 0.0056 0.0042 0.0021 0.0003 0.0005 0.0011 0.0017 0.0003 0.0107 0.0014 0.008 0.0231 0.0695 0.0006
Punctate Nuclear 0.0101 0.0029 0.0019 0.0174 0.0024 0.0041 0.0019 0.0003 0.0007 0.0172 0.0017 0.0009 0.004 0.0004 0.0006 0.0047 0.0012 0.0002
Vacuole 0.0083 0.0014 0.002 0.0045 0.0022 0.0046 0.0022 0.001 0.012 0.0017 0.0012 0.0024 0.0044 0.001 0.0014 0.0016 0.0013 0.0019
Vacuole Periphery 0.0026 0.0002 0.0004 0.0014 0.0026 0.0012 0.0006 0.0001 0.001 0.0002 0.0019 0.0002 0.0004 0.0001 0.0002 0.0005 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.1187 6.3637 3.1481 3.6774 5.384 13.0438 5.8982 6.1522 8.6897 5.3616
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
386 434 1512 558 1921 837 116 421 2307 1271 1628 979

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 628.20 770.72 735.95 789.19 647.62 719.11 899.33 782.43 644.37 736.73 747.59 786.28
Standard Deviation 65.77 231.59 217.47 728.93 135.55 138.39 121.44 139.64 126.79 177.55 216.20 557.89
Intensity Change Log 2 — 0.294983 0.228384 0.329149 — 0.151065 0.473703 0.272814 — 0.223723 0.358113 0.300828

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000201 0.034906 0.013892 0.014899 0.002876 0.007457 0.005042 0.044591 0.002428 0.016830 0.013262 0.027668
Bud Neck 0.016325 0.052144 0.011879 0.006405 0.021996 0.043893 0.003060 0.014978 0.021048 0.046710 0.011251 0.010092
Bud Site 0.003133 0.169140 0.085327 0.071711 0.021839 0.037263 0.005906 0.056615 0.018709 0.082295 0.079668 0.065220
Cell Periphery 0.000298 0.047117 0.032217 0.014071 0.008185 0.008724 0.002251 0.009109 0.006865 0.021834 0.030082 0.011938
Cytoplasm 0.364731 0.243784 0.341971 0.424167 0.442453 0.341537 0.267938 0.364767 0.429449 0.308158 0.336696 0.398623
Cytoplasmic Foci 0.337746 0.212099 0.026208 0.045844 0.198794 0.240353 0.038247 0.075296 0.222043 0.230705 0.027066 0.058509
Eisosomes 0.000362 0.016366 0.002862 0.001922 0.001086 0.003325 0.007149 0.008910 0.000965 0.007778 0.003167 0.004927
Endoplasmic Reticulum 0.000616 0.003519 0.002876 0.002689 0.003680 0.002410 0.005574 0.004499 0.003167 0.002789 0.003068 0.003467
Endosome 0.016956 0.022203 0.003411 0.007090 0.012241 0.025591 0.006335 0.013954 0.013029 0.024434 0.003619 0.010041
Golgi 0.003297 0.007270 0.000426 0.001620 0.003311 0.008152 0.000102 0.005683 0.003309 0.007851 0.000403 0.003367
Lipid Particles 0.012742 0.009441 0.004957 0.002562 0.015801 0.009542 0.004943 0.010943 0.015289 0.009508 0.004956 0.006166
Mitochondria 0.004065 0.009618 0.001749 0.004314 0.005908 0.015374 0.000321 0.006660 0.005599 0.013409 0.001648 0.005323
Mitotic Spindle 0.000152 0.001975 0.004799 0.012746 0.000234 0.009045 0.000273 0.004813 0.000221 0.006631 0.004476 0.009335
None 0.001825 0.001896 0.003688 0.006374 0.004185 0.003465 0.003340 0.005131 0.003790 0.002929 0.003663 0.005839
Nuclear Periphery 0.000545 0.000274 0.001100 0.000911 0.000628 0.000498 0.001923 0.000767 0.000614 0.000421 0.001159 0.000849
Nuclear Periphery Foci 0.000350 0.000635 0.000526 0.001291 0.000252 0.000332 0.002839 0.001195 0.000268 0.000435 0.000691 0.001250
Nucleolus 0.001518 0.001217 0.000828 0.000473 0.001033 0.001909 0.000793 0.000696 0.001114 0.001673 0.000826 0.000569
Nucleus 0.180448 0.075925 0.415034 0.227584 0.199134 0.140334 0.540778 0.199005 0.196008 0.118341 0.423993 0.215294
Peroxisomes 0.015475 0.036168 0.001637 0.002567 0.004652 0.022404 0.000503 0.009451 0.006463 0.027104 0.001556 0.005527
Vacuole 0.038551 0.052416 0.043577 0.149128 0.050397 0.075987 0.102490 0.157782 0.048415 0.067938 0.047774 0.152849
Vacuole Periphery 0.000663 0.001886 0.001035 0.001632 0.001315 0.002409 0.000193 0.005157 0.001206 0.002230 0.000975 0.003148

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.62 -6.44 -3.11 3.80 1.01 -2.57 -0.08 -4.12 -3.32 -3.84 -5.82 -4.93 -4.69 -0.19 -1.58
Bud Neck -5.99 1.79 3.94 8.65 4.10 -5.77 10.88 3.86 7.73 -2.80 -7.96 6.31 7.59 12.42 1.81
Bud Site -11.88 -13.27 -6.25 7.79 3.36 -2.83 5.61 -2.31 -0.28 -4.73 -10.05 -9.48 -4.56 4.94 3.93
Cell Periphery -6.13 -8.09 -2.52 4.68 4.28 -0.10 3.56 0.88 0.85 -1.72 -4.35 -5.53 -0.09 3.90 5.02
Cytoplasm 6.87 2.00 -0.40 -7.27 -2.48 9.17 11.66 7.16 0.31 -5.08 13.16 12.12 7.10 -3.90 -2.59
Cytoplasmic Foci 7.59 26.82 25.19 14.97 -4.40 -4.56 22.97 20.57 19.69 -4.28 -1.17 41.75 33.65 26.46 -7.71
Eisosomes -4.21 -4.75 -1.11 3.92 1.58 -1.91 -0.75 -2.06 -0.96 -0.40 -4.46 -3.10 -2.02 2.53 -0.41
Endoplasmic Reticulum -2.30 -6.66 -8.58 -0.00 -0.84 1.20 -3.41 0.11 -0.98 3.28 0.46 -0.44 -0.50 -0.94 -0.11
Endosome -1.76 5.84 4.53 6.74 -1.56 -6.14 4.49 1.09 5.80 -1.82 -6.67 10.51 4.37 9.37 -3.47
Golgi -2.29 3.74 2.65 3.94 -1.32 -3.47 10.37 -0.20 2.61 -3.15 -4.20 9.93 2.06 4.96 -3.19
Lipid Particles 1.38 5.00 8.40 3.77 1.82 3.84 9.35 3.89 0.82 -1.34 4.20 8.13 9.17 3.58 -0.10
Mitochondria -2.92 2.04 0.78 3.38 -0.75 -3.72 7.06 0.76 3.47 -1.85 -4.30 5.15 1.67 4.91 -1.46
Mitotic Spindle -2.94 -4.17 -3.34 -2.65 -1.50 -3.83 -1.51 -3.16 0.62 -2.75 -4.19 -4.15 -4.42 -0.88 -1.71
None -0.09 -2.91 -1.81 -1.68 -0.64 0.50 1.72 -0.13 -0.50 -1.27 0.87 0.42 -0.55 -1.23 -0.91
Nuclear Periphery 3.06 -6.71 -6.65 -10.64 -1.10 1.44 -7.18 -4.20 -5.02 5.34 2.88 -9.01 -7.72 -10.04 0.99
Nuclear Periphery Foci -2.32 -2.55 -7.96 -4.70 -6.52 -1.65 -6.20 -4.43 -3.73 4.16 -3.25 -7.19 -9.52 -7.06 -4.43
Nucleolus 0.39 1.79 3.25 3.82 2.26 -3.03 1.78 3.01 4.29 0.91 -2.85 1.33 5.30 5.60 1.98
Nucleus 8.93 -19.87 -5.12 -14.21 13.71 7.19 -12.99 -1.74 -5.89 11.25 11.81 -26.78 -4.90 -12.95 18.03
Peroxisomes -3.87 5.29 5.20 7.32 -0.27 -8.02 11.50 -0.92 5.68 -3.30 -9.25 8.52 2.91 10.15 -2.64
Vacuole -2.81 -3.10 -17.21 -15.54 -16.28 -5.75 -6.00 -14.10 -11.49 -3.80 -5.83 -3.41 -21.88 -18.45 -19.91
Vacuole Periphery -3.16 -0.74 -0.59 1.32 -0.09 -3.28 8.77 -1.45 -0.64 -2.30 -3.88 0.95 -1.14 0.36 -1.48
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Integral membrane protein localized to mitochondria; required for sporulation and maintaining sphingolipid content; similar to SUR7; FMP45 has a paralog, YNL194C, that arose from the whole genome duplication
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Fmp45

Fmp45


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fmp45-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available