Standard name
Human Ortholog
Description Protein with similarity to a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; PST2 has a paralog, RFS1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.53 0.45 0.41 0.4 0.27 0.44 0.45 – 0.48 0.44 0.49 0.46 0.31 0.2 0.16 0.14 0.23 0.32 0.2 0.12 0 0 0 0
Bud 0.08 0.09 0.06 0.05 0 0.1 0.06 – 0.08 0.09 0.05 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.56 0.78 0.76 0.7 0.56 0.47 0.56 – 0.48 0.56 0.51 0.56 0.91 0.92 0.91 0.81 0.81 0.79 0.71 0.76 0.87 0.9 0.94 0.86
Cytoplasm 0.06 0.1 0.09 0.09 0.1 0.16 0.1 – 0.06 0.1 0.07 0.06 0 0 0 0.08 0.05 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0.06 0 0 0.07 0 0.08 0.09 – 0.12 0.05 0.11 0.09 0 0 0 0.07 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.12 0 0 0 0.35 0 0.2 – 0 0.14 0.11 0.16 0 0 0 0.12 0.16 0.08 0 0 0 0 0 0
Mitochondria 0.32 0.19 0.07 0.18 0 0.39 0.11 – 0.46 0.28 0.45 0.35 0.09 0.08 0.07 0.11 0.11 0.12 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.06 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 120 73 95 81 78 117 159 – 157 161 147 176 64 74 48 33 61 52 50 22 11 7 12 11
Bud 18 15 14 11 9 27 23 – 27 32 16 34 9 10 6 2 7 3 3 1 3 3 3 3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 3 2 2 0 3
Bud Site 0 0 1 0 0 1 0 – 0 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 126 127 175 141 159 125 200 – 159 202 150 215 187 341 279 190 213 129 181 146 236 204 451 305
Cytoplasm 14 16 20 19 28 43 37 – 20 35 22 22 7 11 9 18 13 13 1 1 1 3 1 4
Endoplasmic Reticulum 13 3 6 14 5 22 32 – 40 17 32 33 5 13 10 16 4 11 10 3 3 1 5 13
Endosome 1 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1
Golgi 27 1 5 6 100 3 71 – 13 51 33 61 1 2 3 28 43 13 2 3 0 0 0 0
Mitochondria 73 31 15 37 7 105 39 – 151 100 133 133 18 29 23 26 29 20 1 4 5 1 3 3
Nucleus 0 0 0 1 1 1 0 – 1 2 1 1 0 0 0 1 1 0 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 1 0 1 – 3 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1
Nucleolus 0 0 0 0 1 0 0 – 0 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 13 1 0 5 1 1 3 – 3 8 0 2 9 4 7 0 2 1 0 0 0 0 0 0
SpindlePole 0 2 7 7 16 1 2 – 0 6 0 2 1 0 0 0 1 3 0 0 0 0 0 0
Vac/Vac Membrane 1 0 0 6 16 1 5 – 0 7 0 4 0 0 0 1 2 1 2 1 1 0 1 2
Unique Cell Count 226 162 230 201 285 268 357 330 362 297 382 206 371 308 234 262 163 257 193 271 227 483 355
Labelled Cell Count 406 269 338 328 422 447 572 574 622 536 684 301 484 386 315 376 246 257 193 271 227 483 355


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 12.2 12.7 11.9 11.7 15.2 11.6 14.7 – 14.2 15.0 14.6 15.1 16.1 18.4 19.6 24.9 25.2 25.1 11.9 12.8 13.3
Std Deviation (1e-4) 2.2 2.5 2.9 1.9 5.4 3.0 2.6 – 2.8 3.0 3.3 3.5 2.7 3.3 3.9 6.3 6.8 6.7 8.6 6.3 6.5
Intensity Change (Log2) – – – -0.03 0.35 -0.04 0.3 – 0.25 0.33 0.3 0.35 0.43 0.63 0.72 1.06 1.08 1.07 0.0 0.1 0.16

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.2 -3.3 0.5 0.8 – 1.5 0.8 1.9 1.2 -2.2 -5.7 -6.7 -6.6 -4.3 -1.9
Bud -0.3 -1.6 1.6 0.2 – 0.9 1.2 -0.3 1.3 -0.8 -2.1 -2.5 -3.1 -1.9 -2.0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.4 -4.8 -6.7 -4.9 – -6.6 -5.0 -6.0 -4.9 4.1 5.4 4.6 1.3 1.4 0.7
Cytoplasm 0.3 0.4 2.5 0.7 – -1.2 0.4 -0.5 -1.4 -2.3 -3.1 -2.9 -0.4 -1.7 -0.3
Endoplasmic Reticulum 2.1 0 2.7 3.1 – 4.0 1.3 3.6 3.0 -0.1 0.6 0.4 2.1 0 2.0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0.5 9.2 0 6.2 – 1.2 4.8 3.9 5.3 0 0 0 4.1 5.3 2.7
Mitochondria 3.8 -2.3 8.5 1.8 – 10.0 6.3 9.7 7.9 0.9 0.6 0.4 1.7 1.8 2.0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.3 1.4 0 0 – 0 -1.1 0 0 0 0 0 0 0 0
Vacuole 0 3.7 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.7868 15.9796 12.9774 11.7799 9.973 12.4227 11.8754 22.629 19.3929 14.6615 14.4062 19.4236 14.7741 24.4687 19.2648 20.7567 17.3916 21.8525
Actin 0.1269 0.0035 0.0073 0.0036 0.0515 0.0436 0.1118 0.0302 0.0241 0.0398 0.032 0.0502 0.0838 0.0453 0.0874 0.0047 0.069 0.0065
Bud 0.0014 0.0002 0.0003 0.0004 0.0013 0.0004 0.0011 0.001 0.0006 0.0003 0.0017 0.0005 0.0017 0.0004 0.0012 0.0003 0.0004 0.0006
Bud Neck 0.0046 0.0033 0.0066 0.003 0.0057 0.002 0.0038 0.0042 0.0054 0.0098 0.015 0.0031 0.0109 0.0034 0.0111 0.0094 0.0019 0.0049
Bud Periphery 0.0056 0.0013 0.0025 0.0087 0.0053 0.0047 0.0065 0.0025 0.0049 0.0027 0.0111 0.0055 0.0053 0.0011 0.0039 0.0037 0.0029 0.0066
Bud Site 0.0274 0.063 0.0267 0.0007 0.0117 0.0015 0.0165 0.1032 0.0348 0.0054 0.0155 0.002 0.0368 0.1484 0.0305 0.0057 0.0026 0.0054
Cell Periphery 0.3021 0.4348 0.4347 0.615 0.3214 0.4947 0.4064 0.3805 0.4567 0.4963 0.4442 0.4582 0.3296 0.4604 0.4026 0.6177 0.3834 0.5939
Cytoplasm 0.0071 0.0072 0.0066 0.0049 0.0049 0.0033 0.0045 0.0072 0.0034 0.0024 0.0049 0.002 0.0115 0.0076 0.0112 0.0039 0.0061 0.0026
Cytoplasmic Foci 0.0078 0.0001 0.0002 0.0001 0.0196 0.0013 0.0016 0.0001 0.0002 0.0002 0.0109 0.0015 0.0094 0.003 0.0161 0.0001 0.0104 0.001
Eisosomes 0.4269 0.4792 0.4904 0.3286 0.3833 0.4205 0.4279 0.4631 0.4591 0.425 0.3072 0.4616 0.3567 0.2793 0.3454 0.3417 0.4196 0.3439
Endoplasmic Reticulum 0.0091 0.0027 0.0056 0.0264 0.0043 0.0055 0.0036 0.0019 0.0041 0.0062 0.0045 0.003 0.0079 0.0021 0.0136 0.006 0.0029 0.0044
Endosome 0.0143 0 0.0001 0.0001 0.0164 0.0016 0.0007 0 0 0.0001 0.0289 0.0006 0.0259 0.0005 0.0064 0.0001 0.0014 0.0047
Golgi 0.0061 0.0001 0.0022 0.0007 0.0175 0.0027 0.0032 0.0002 0.0003 0.001 0.0142 0.0021 0.0156 0.0018 0.0055 0.0007 0.0061 0.0045
Lipid Particles 0.0046 0.0001 0.0011 0.0005 0.0256 0.0028 0.0018 0.0002 0.0003 0.0004 0.0394 0.0011 0.0131 0.0021 0.0136 0.0004 0.0089 0.0011
Mitochondria 0.0238 0.0016 0.012 0.0022 0.093 0.0109 0.004 0.0032 0.0023 0.0059 0.0231 0.0044 0.0413 0.0275 0.0287 0.0016 0.0113 0.0158
None 0.0041 0.0009 0.0008 0.0012 0.0065 0.0009 0.0011 0.0006 0.0008 0.0011 0.0029 0.0008 0.0056 0.0008 0.0083 0.001 0.0012 0.0007
Nuclear Periphery 0.0134 0.0008 0.0009 0.0021 0.0041 0.0008 0.0009 0.0006 0.001 0.001 0.0198 0.0007 0.0093 0.0007 0.0025 0.001 0.0005 0.0008
Nucleolus 0.0006 0.0001 0.0001 0.0001 0.0009 0.0001 0.0002 0.0001 0.0001 0.0001 0.0014 0.0001 0.0009 0.0001 0.0007 0.0001 0.0001 0.0001
Nucleus 0.0024 0.0001 0.0001 0.0001 0.0011 0.0002 0.0002 0.0001 0.0001 0.0001 0.0015 0.0001 0.0189 0.0001 0.0006 0.0001 0.0001 0.0001
Peroxisomes 0.0021 0.0001 0.0003 0 0.0112 0.0011 0.0005 0.0001 0.0002 0.0002 0.0069 0.0009 0.0038 0.0139 0.0055 0.0001 0.0701 0.0003
Punctate Nuclear 0.005 0 0 0 0.0084 0.0002 0.0007 0 0 0 0.0034 0.0001 0.0072 0.0001 0.0019 0 0.0004 0
Vacuole 0.003 0.0008 0.0012 0.0015 0.0051 0.0013 0.0028 0.0009 0.0015 0.0019 0.0048 0.0015 0.0033 0.0013 0.0029 0.0016 0.0006 0.0018
Vacuole Periphery 0.0017 0 0.0001 0.0001 0.0011 0.0001 0.0002 0 0.0001 0.0001 0.0068 0.0001 0.0016 0.0001 0.0007 0.0001 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 158.9494 153.6566 144.6703 157.9124 176.1306 169.9447 184.5968 187.7312 267.2033 213.2288
Translational Efficiency 2.7411 2.2176 2.2852 2.7339 2.4416 3.061 2.5126 2.8096 2.1075 2.6742

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1796 536 1582 1071 1757 1533 1857 1217 3553 2069 3439 2288

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1143.21 1518.96 2084.12 1872.22 1152.63 1401.93 1655.32 2180.86 1147.87 1432.25 1852.58 2036.39
Standard Deviation 204.68 275.92 389.62 413.90 233.53 250.51 310.29 450.57 219.47 262.39 409.26 460.32
Intensity Change Log 2 — 0.409993 0.866348 0.711660 — 0.282485 0.522181 0.919968 — 0.347386 0.703800 0.819997

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.068727 0.037280 0.023147 0.035644 0.062039 0.054685 0.047423 0.013984 0.065420 0.050176 0.036255 0.024123
Bud Neck 0.007728 0.010815 0.010801 0.008695 0.007395 0.006916 0.010021 0.003053 0.007563 0.007926 0.010380 0.005694
Bud Site 0.008933 0.007895 0.006514 0.009050 0.007383 0.010682 0.005285 0.004246 0.008167 0.009960 0.005850 0.006495
Cell Periphery 0.628469 0.679027 0.562247 0.531064 0.537752 0.644870 0.471823 0.650750 0.583609 0.653719 0.513420 0.594726
Cytoplasm 0.001463 0.000364 0.000088 0.000092 0.000516 0.001189 0.000109 0.000384 0.000995 0.000975 0.000100 0.000247
Cytoplasmic Foci 0.001300 0.001460 0.000216 0.000798 0.001218 0.002166 0.000422 0.000137 0.001259 0.001983 0.000327 0.000446
Eisosomes 0.249874 0.201465 0.353093 0.341453 0.353827 0.213949 0.404035 0.316945 0.301280 0.210715 0.380601 0.328417
Endoplasmic Reticulum 0.013915 0.035322 0.026970 0.041539 0.012935 0.023964 0.032787 0.004138 0.013430 0.026907 0.030111 0.021645
Endosome 0.004790 0.006940 0.003958 0.005182 0.003508 0.008550 0.006009 0.000887 0.004156 0.008133 0.005065 0.002898
Golgi 0.001017 0.004800 0.001919 0.007074 0.001196 0.004772 0.004101 0.000434 0.001106 0.004779 0.003097 0.003542
Lipid Particles 0.001805 0.003922 0.002394 0.010675 0.001690 0.008207 0.010282 0.000225 0.001748 0.007097 0.006653 0.005117
Mitochondria 0.002771 0.003983 0.002610 0.003675 0.002626 0.004838 0.002172 0.003050 0.002699 0.004616 0.002373 0.003343
Mitotic Spindle 0.001951 0.001718 0.001515 0.000852 0.002547 0.001636 0.001241 0.000596 0.002246 0.001657 0.001367 0.000716
None 0.000553 0.000217 0.000186 0.000186 0.000732 0.000308 0.000285 0.000112 0.000641 0.000284 0.000240 0.000147
Nuclear Periphery 0.000629 0.000691 0.001971 0.001055 0.000651 0.001054 0.000981 0.000377 0.000640 0.000960 0.001436 0.000694
Nuclear Periphery Foci 0.000095 0.000236 0.000087 0.000103 0.000053 0.000083 0.000066 0.000018 0.000075 0.000123 0.000076 0.000058
Nucleolus 0.000023 0.000039 0.000041 0.000038 0.000019 0.000024 0.000024 0.000027 0.000021 0.000028 0.000032 0.000032
Nucleus 0.000431 0.000185 0.000205 0.000155 0.000218 0.000232 0.000176 0.000091 0.000326 0.000220 0.000189 0.000121
Peroxisomes 0.005053 0.000967 0.000172 0.000241 0.003383 0.011077 0.001943 0.000033 0.004227 0.008458 0.001128 0.000130
Vacuole 0.000349 0.001320 0.001492 0.001562 0.000216 0.000535 0.000598 0.000350 0.000283 0.000739 0.001009 0.000917
Vacuole Periphery 0.000123 0.001353 0.000375 0.000869 0.000095 0.000264 0.000216 0.000164 0.000109 0.000546 0.000290 0.000494

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 4.87 10.23 6.42 0.27 -3.21 1.32 3.01 10.87 8.97 9.20 3.58 8.75 12.24 6.90 4.53
Bud Neck -2.78 -3.85 -1.38 1.76 2.30 0.81 -4.02 9.85 7.03 11.33 -0.70 -5.52 4.54 4.06 8.66
Bud Site 0.71 2.03 -0.07 -0.66 -1.64 -1.83 1.89 2.15 3.52 0.88 -1.34 2.87 1.52 2.42 -0.71
Cell Periphery -3.13 5.82 7.33 8.29 2.28 -9.08 5.70 -8.82 -0.45 -14.01 -7.60 8.58 -1.19 5.69 -8.60
Cytoplasm 2.56 3.40 3.40 1.81 -0.09 -2.04 4.37 0.40 1.79 -0.86 0.07 4.27 2.78 2.49 -0.87
Cytoplasmic Foci -0.28 9.18 0.84 0.81 -0.99 -1.96 7.83 12.63 4.25 4.24 -1.86 11.78 2.86 3.26 -0.43
Eisosomes 3.86 -10.07 -7.91 -9.74 0.94 14.05 -4.72 3.07 -9.06 7.27 12.06 -10.66 -3.23 -13.53 6.04
Endoplasmic Reticulum -4.75 -5.95 -7.12 -1.08 -3.46 -5.17 -7.23 5.94 10.77 11.34 -7.15 -9.34 -4.09 2.10 3.49
Endosome -2.13 2.87 -0.85 1.64 -2.73 -7.80 -6.37 12.65 12.24 14.28 -7.30 -3.60 5.01 9.29 7.47
Golgi -3.09 -4.54 -5.89 -1.43 -4.98 -4.96 -5.10 2.76 6.44 7.21 -6.06 -6.28 -4.82 1.62 -0.79
Lipid Particles -1.69 -0.88 -4.80 -3.07 -4.30 -4.56 -6.78 4.35 5.73 8.19 -4.86 -6.52 -3.79 1.43 1.36
Mitochondria -0.99 0.41 -1.31 0.23 -1.52 -2.55 1.88 -0.50 1.51 -1.04 -2.67 1.44 -1.15 1.45 -1.74
Mitotic Spindle 1.37 3.97 10.60 5.73 8.46 4.88 6.54 9.67 7.58 4.18 4.97 7.64 13.36 9.95 7.21
None 4.90 5.53 5.50 1.47 -0.02 3.94 4.22 5.96 6.48 7.65 5.49 6.45 8.04 5.98 6.82
Nuclear Periphery -0.91 -14.70 -4.61 -3.49 7.59 -5.79 -5.63 6.25 9.97 10.67 -5.98 -14.96 -1.09 4.09 11.47
Nuclear Periphery Foci -1.33 0.27 -0.17 1.35 -1.46 -1.81 -2.43 9.59 4.06 10.74 -1.41 -0.02 0.91 2.27 3.06
Nucleolus -0.88 -3.16 -2.82 0.08 0.93 -1.55 -3.90 -5.25 -1.10 -2.27 -1.14 -3.66 -3.97 -0.87 -0.35
Nucleus 1.14 1.05 1.28 1.75 4.31 -0.32 4.07 12.89 3.32 11.23 0.94 1.25 1.85 3.10 10.07
Peroxisomes 5.59 8.04 7.88 1.75 -0.90 -5.65 2.45 6.49 8.76 6.76 -4.12 7.25 10.23 8.80 6.33
Vacuole -2.16 -6.21 -3.00 -0.43 -0.19 -1.32 -6.97 -3.91 0.76 4.02 -2.02 -7.57 -3.29 -0.66 0.50
Vacuole Periphery -1.74 -10.89 -2.31 0.63 -1.53 -3.99 -5.73 -2.55 2.06 1.65 -2.34 -11.46 -2.53 0.22 -1.34
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with similarity to a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; PST2 has a paralog, RFS1, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (83%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-2

Pst2

Pst2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pst2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available