Standard name
Human Ortholog
Description Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.1 0.07 0 0 0 0 0 0
Cytoplasm 0.94 0.97 0.93 0.98 0.97 0.92 0.88 – 0.78 0.74 0.64 0.72 1.0 0.99 0.99 0.89 0.84 0.9 0.9 0.97 0.94 0.93 0.92 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.07 0 0 0 0.19 0.12 – 0.24 0.34 0.49 0.37 0 0 0 0.07 0.15 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 1 1 0 1 – 1 0 3 4 0 0 0 0 0 1 0 0 0 0 0 2
Bud 2 0 1 0 0 4 1 – 4 4 11 7 1 0 0 0 0 0 0 0 0 1 3 0
Bud Neck 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 0 0 3 6 2 6 – 5 6 3 7 8 13 17 8 8 4 0 0 0 0 0 1
Cytoplasm 245 72 64 182 250 173 295 – 125 165 169 254 343 478 563 132 66 53 266 90 80 283 359 399
Endoplasmic Reticulum 0 0 2 0 2 0 1 – 2 1 0 6 1 1 3 9 5 1 11 0 1 4 8 7
Endosome 4 0 0 0 0 0 3 – 0 4 6 2 0 1 1 1 1 0 4 0 0 1 1 3
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 4 5 2
Mitochondria 11 5 1 7 1 36 39 – 39 76 129 129 0 2 0 10 12 1 5 1 0 5 5 6
Nucleus 2 0 2 1 0 2 1 – 4 2 5 3 0 0 0 5 3 2 0 0 0 1 0 0
Nuclear Periphery 1 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 2 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 2 – 0 1 1 2 0 0 0 0 0 0 0 0 0 0 1 2
Vac/Vac Membrane 10 0 0 1 2 0 14 – 3 4 9 10 0 4 0 7 4 4 3 1 0 1 1 3
Unique Cell Count 261 74 69 185 257 189 337 161 222 264 351 344 484 566 148 79 59 298 93 86 306 390 436
Labelled Cell Count 280 77 71 195 264 217 364 183 263 338 425 353 500 584 174 99 67 298 93 86 306 390 436


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 5.2 5.4 6.2 6.7 4.5 5.8 – 5.0 7.8 7.2 6.6 7.1 7.3 7.6 8.2 8.2 8.1 6.1 6.3 6.6
Std Deviation (1e-4) 0.9 0.6 0.4 1.3 1.5 1.4 1.5 – 1.1 14.0 15.7 9.3 1.0 1.2 1.3 1.9 2.4 1.8 1.1 1.5 1.3
Intensity Change (Log2) – – – 0.2 0.33 -0.25 0.1 – -0.12 0.54 0.43 0.28 0.39 0.44 0.49 0.61 0.6 0.6 0.18 0.22 0.29


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.3 1.8 -0.3 -1.2 – -2.7 -3.3 -4.6 -3.6 4.4 3.3 4.7 -0.8 -1.7 -0.6
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 2.6 – 4.2 5.4 7.2 5.8 0 0 0 0 2.9 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.7418 0.0379 -0.1046 -0.4677 -0.4573 -0.2624 1.3469 2.0358 1.7497 1.601 1.6256 1.733 2.5942 3.6419 3.1853 3.0516 2.6771 3.259
Actin 0.0335 0.0028 0.0159 0.0004 0.0043 0.0005 0.0411 0.0024 0.0079 0.0046 0.0174 0.0114 0.0022 0.0003 0.0006 0.0009 0.0021 0.002
Bud 0.0005 0.0003 0.0006 0.0001 0.0031 0.0003 0.0016 0.015 0.0072 0.0066 0.0502 0.0012 0.0003 0.0011 0.0008 0.0014 0.0008 0.0001
Bud Neck 0.0032 0.0002 0.0004 0.0002 0.0029 0.0006 0.0024 0.0003 0.0014 0.0007 0.0007 0.0031 0.0041 0.0002 0.0005 0.0002 0.0003 0.0003
Bud Periphery 0.0005 0.0002 0.0004 0.0001 0.0022 0.0001 0.0011 0.0075 0.0041 0.0098 0.0332 0.0012 0.0005 0.0011 0.0024 0.0027 0.0008 0.0001
Bud Site 0.0028 0.0026 0.0032 0.0001 0.0164 0.0001 0.0166 0.0166 0.0194 0.0049 0.0067 0.0062 0.0019 0.0072 0.0021 0.0008 0.0005 0
Cell Periphery 0.0004 0.0005 0.0002 0.0001 0.0003 0.0001 0.0008 0.0006 0.0005 0.0004 0.0009 0.0001 0.0006 0.0003 0.0007 0.0002 0.0001 0.0001
Cytoplasm 0.5946 0.705 0.675 0.6376 0.7932 0.7693 0.5518 0.7636 0.7211 0.7106 0.5912 0.8136 0.5818 0.7231 0.6877 0.619 0.6818 0.7385
Cytoplasmic Foci 0.0258 0.0324 0.0247 0.0365 0.0254 0.0241 0.0766 0.011 0.017 0.0299 0.0307 0.0254 0.0166 0.0101 0.0155 0.022 0.0142 0.0068
Eisosomes 0.0002 0.0001 0.0001 0.0001 0.0001 0.0003 0.0004 0.0001 0.0003 0.0001 0.0001 0 0.0002 0.0001 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0107 0.0098 0.0076 0.0098 0.0062 0.0042 0.0112 0.0023 0.0034 0.0033 0.0026 0.0018 0.009 0.0029 0.0032 0.0032 0.0044 0.0033
Endosome 0.0499 0.0407 0.0535 0.0657 0.0296 0.0349 0.0341 0.0064 0.0332 0.0547 0.0216 0.0157 0.0109 0.0053 0.0115 0.0282 0.016 0.006
Golgi 0.0041 0.0026 0.0028 0.0011 0.0021 0.0015 0.0098 0.0005 0.0069 0.0063 0.0091 0.0056 0.0025 0.0004 0.0006 0.0017 0.0008 0.0004
Lipid Particles 0.0032 0.0013 0.0025 0.0009 0.0007 0.0005 0.0113 0.0002 0.003 0.0006 0.0135 0.0077 0.0033 0.0002 0.0004 0.0021 0.0003 0.0002
Mitochondria 0.0014 0.0008 0.0013 0.0003 0.0015 0.0008 0.0059 0.0036 0.0073 0.0203 0.0432 0.0038 0.003 0.0003 0.0003 0.0008 0.0003 0.0004
None 0.2429 0.1835 0.1941 0.2299 0.0972 0.154 0.1707 0.1641 0.1559 0.1246 0.1297 0.0871 0.3471 0.2426 0.2665 0.3077 0.2707 0.2368
Nuclear Periphery 0.0048 0.0016 0.0018 0.0022 0.0022 0.0008 0.0092 0.0005 0.0011 0.0015 0.001 0.0003 0.0009 0.0005 0.0006 0.0011 0.0006 0.0025
Nucleolus 0.0007 0.0002 0.0001 0.0001 0.0003 0.0001 0.0008 0.0002 0.0003 0.0003 0.0003 0 0.0002 0.0001 0.0001 0.0002 0.0001 0
Nucleus 0.005 0.0012 0.0011 0.0015 0.0033 0.001 0.0104 0.0011 0.0014 0.0018 0.0012 0.0005 0.0009 0.001 0.0008 0.001 0.0009 0.0005
Peroxisomes 0.001 0.0004 0.0003 0.0002 0.0007 0.0002 0.0239 0.0002 0.0019 0.0014 0.038 0.0127 0.0091 0.0001 0.0002 0.0004 0.0001 0.0001
Punctate Nuclear 0.0036 0.0011 0.0006 0.001 0.0014 0.0004 0.0133 0.0005 0.001 0.0018 0.0022 0.0005 0.0007 0.0005 0.0012 0.0005 0.0007 0.0003
Vacuole 0.0098 0.0114 0.0121 0.009 0.0061 0.0055 0.0054 0.0028 0.0047 0.0134 0.0052 0.0015 0.0036 0.0023 0.0037 0.0048 0.004 0.0012
Vacuole Periphery 0.0014 0.0013 0.0017 0.003 0.0011 0.001 0.0013 0.0005 0.001 0.0024 0.0011 0.0004 0.0004 0.0002 0.0004 0.0009 0.0005 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.7028 10.2291 15.1808 14.6861 19.0748 11.4364 15.5139 12.9639 13.2738 12.5147
Translational Efficiency 0.3674 0.7964 0.509 0.5473 0.4081 0.9308 0.6157 0.6835 0.8006 0.8695

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1202 878 1795 1147 2063 2170 2163 1869 3265 3048 3958 3016

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 744.08 715.60 935.72 876.51 758.88 836.48 869.33 912.34 753.43 801.66 899.44 898.71
Standard Deviation 85.14 116.98 124.94 125.47 87.59 103.29 107.63 115.75 86.99 120.55 120.43 120.80
Intensity Change Log 2 — -0.056304 0.330619 0.236313 — 0.140459 0.196032 0.265700 — 0.046396 0.264232 0.251226

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000354 0.000317 0.000110 0.001499 0.000141 0.000282 0.000077 0.000341 0.000220 0.000292 0.000092 0.000781
Bud Neck 0.014266 0.009418 0.002244 0.003094 0.008747 0.015440 0.002902 0.003934 0.010779 0.013705 0.002604 0.003614
Bud Site 0.016724 0.032034 0.009805 0.019661 0.008474 0.028583 0.006916 0.022483 0.011511 0.029577 0.008226 0.021409
Cell Periphery 0.000173 0.000149 0.000125 0.000115 0.000127 0.000138 0.000065 0.000094 0.000144 0.000141 0.000092 0.000102
Cytoplasm 0.543570* 0.558839* 0.647178* 0.616331* 0.535748* 0.607696* 0.714963* 0.695746* 0.538627* 0.593622* 0.684222* 0.665544*
Cytoplasmic Foci 0.254636* 0.206561* 0.021583 0.043235 0.240493* 0.180898* 0.020607 0.030300 0.245700* 0.188291* 0.021049 0.035219
Eisosomes 0.000243 0.000055 0.000037 0.000036 0.000108 0.000096 0.000020 0.000021 0.000158 0.000084 0.000028 0.000026
Endoplasmic Reticulum 0.001967 0.001697 0.001059 0.000991 0.002452 0.000530 0.000715 0.000559 0.002274 0.000866 0.000871 0.000723
Endosome 0.019139 0.037293 0.002677 0.009807 0.025755 0.020902 0.001898 0.003727 0.023319 0.025624 0.002251 0.006039
Golgi 0.019469 0.007502 0.000160 0.004454 0.008898 0.007758 0.000118 0.000922 0.012790 0.007684 0.000137 0.002265
Lipid Particles 0.005418 0.002497 0.001154 0.000935 0.005089 0.001999 0.000577 0.000525 0.005210 0.002142 0.000839 0.000681
Mitochondria 0.008230 0.002975 0.000230 0.002117 0.001972 0.003306 0.000223 0.001486 0.004276 0.003211 0.000226 0.001726
Mitotic Spindle 0.001126 0.000655 0.002354 0.030327 0.000510 0.004549 0.007217 0.020111 0.000737 0.003427 0.005011 0.023996
None 0.002205 0.004901 0.004331 0.002936 0.001345 0.001479 0.004132 0.003051 0.001662 0.002465 0.004222 0.003007
Nuclear Periphery 0.000097 0.000123 0.000729 0.000468 0.000217 0.000075 0.000569 0.000502 0.000173 0.000089 0.000641 0.000489
Nuclear Periphery Foci 0.000156 0.000703 0.001663 0.001628 0.000275 0.000203 0.001060 0.001173 0.000231 0.000347 0.001333 0.001346
Nucleolus 0.000397 0.001147 0.000292 0.000202 0.000395 0.000426 0.000259 0.000227 0.000396 0.000634 0.000274 0.000217
Nucleus 0.028746 0.021823 0.208497* 0.053874 0.032939 0.024171 0.142115* 0.070095 0.031395 0.023495 0.172220* 0.063926
Peroxisomes 0.002863 0.002920 0.000143 0.001281 0.001883 0.003081 0.000141 0.000684 0.002244 0.003034 0.000142 0.000911
Vacuole 0.074949 0.102243 0.095391 0.204875* 0.120863 0.095531 0.095211 0.142716 0.103960 0.097465 0.095293 0.166355
Vacuole Periphery 0.005271 0.006146 0.000238 0.002135 0.003570 0.002855 0.000216 0.001306 0.004196 0.003803 0.000226 0.001621

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.30 2.06 -1.11 -1.24 -1.78 -2.81 2.50 -1.61 0.74 -2.51 -1.32 2.57 -1.49 -0.97 -2.31
Bud Neck 4.23 12.42 11.87 9.10 -0.87 -6.74 8.24 8.50 13.67 -0.77 -3.65 14.58 14.21 16.06 -1.16
Bud Site -5.96 4.23 1.64 6.78 -2.23 -12.04 3.63 -3.51 6.95 -5.31 -12.73 4.94 -1.80 9.46 -5.20
Cell Periphery 1.88 4.85 8.84 5.34 2.61 -1.12 10.90 7.33 6.99 -1.86 0.37 9.38 11.16 8.59 1.30
Cytoplasm -1.30 -6.65 2.34 3.23 8.25 -9.21 -13.96 -8.42 0.02 4.47 -8.51 -14.73 -5.05 2.88 8.12
Cytoplasmic Foci 5.88 41.26 37.43 26.54 -7.24 10.65 51.53 48.64 39.42 -6.87 12.47 65.96 61.29 47.16 -9.84
Eisosomes 9.46 10.53 10.52 4.26 -0.36 1.93 19.58 19.51 14.60 -0.81 8.62 16.44 16.56 14.74 0.01
Endoplasmic Reticulum 0.69 1.85 3.30 2.31 3.28 5.77 4.61 5.57 -1.08 4.21 5.64 4.76 6.44 1.05 5.66
Endosome -6.44 15.58 10.94 11.92 -2.92 3.12 21.21 20.09 16.50 -3.06 -1.63 25.88 22.66 19.56 -3.78
Golgi 10.17 20.13 16.16 6.46 -3.02 1.89 18.90 17.44 17.10 -2.41 8.81 27.04 22.93 16.20 -3.70
Lipid Particles 6.77 10.71 11.93 6.44 1.26 10.28 18.08 18.10 7.58 -0.23 12.32 19.98 21.42 9.49 1.45
Mitochondria 3.99 8.20 7.08 2.08 -2.14 -3.05 13.24 2.80 4.32 -1.20 2.01 10.83 7.35 4.86 -2.02
Mitotic Spindle 0.94 -2.23 -5.83 -6.07 -5.26 -3.77 -6.10 -6.84 -4.08 -2.22 -3.47 -6.55 -8.97 -6.66 -5.37
None -2.25 -2.26 -0.09 2.26 2.35 -0.52 -6.59 -5.35 -4.18 2.77 -2.01 -6.04 -3.64 -0.29 3.50
Nuclear Periphery -1.17 -20.09 -14.55 -13.64 3.60 3.07 -13.20 -8.14 -12.32 2.62 2.68 -20.79 -13.12 -17.32 4.21
Nuclear Periphery Foci -3.04 -10.80 -10.68 -2.44 2.20 1.64 -9.86 -6.57 -6.83 0.32 -2.28 -14.22 -11.24 -7.35 2.11
Nucleolus -3.82 3.04 6.61 4.65 2.64 -0.40 3.35 4.96 2.02 0.74 -2.98 4.43 7.61 4.76 2.08
Nucleus 2.69 -37.85 -13.71 -13.83 25.74 5.45 -36.55 -20.61 -23.28 17.51 5.86 -52.07 -24.64 -27.02 30.01
Peroxisomes -0.21 14.26 7.72 6.48 -2.34 -4.56 10.73 7.49 11.38 -2.17 -3.81 16.86 10.62 12.78 -3.18
Vacuole -5.20 -10.55 -28.34 -23.16 -20.44 5.77 -3.78 -16.59 -21.37 -12.65 1.74 -8.37 -30.14 -31.43 -22.71
Vacuole Periphery -1.18 12.79 8.42 8.01 -1.94 2.66 18.18 11.35 8.26 -2.35 1.48 21.30 13.69 11.13 -2.99
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT
Localization
Cell Percentages cytoplasm (95%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Oca6

Oca6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Oca6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available