Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0.07 0.06 0.06 0.06 0.08 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.1 0 0 0 0 0 0 0
Cytoplasm 0.94 0.86 0.94 0.79 0.8 0.69 0.62 0.49 0.53 0.42 0.37 0.38 0.85 0.92 0.94 0.78 0.87 0.84 0.73 0.75 0.62 0.76 0.76 0.81
Endoplasmic Reticulum 0.05 0.06 0.06 0.09 0.13 0.1 0.1 0.14 0.08 0.05 0.08 0.07 0.16 0.09 0.06 0 0 0 0.13 0.07 0.14 0.11 0.13 0.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0.09 0.12 0 0 0 0.19 0.29 0.36 0.45 0.46 0.63 0.46 0 0 0 0 0 0 0 0 0.09 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.06 0 0 0.06 0.09 0.06 0.12 0 0.14 0 0 0 0.16 0 0.09 0 0.09 0.07 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 1 12 15 13 19 25 15 9 12 20 7 2 4 3 2 3 0 0 0 1 4 1
Bud 0 0 0 1 0 1 4 8 7 6 9 7 0 0 0 0 0 1 0 0 0 0 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 0 4 7 3 13 11 14 11 13 10 5 7 13 9 12 8 0 0 0 1 0 0
Cytoplasm 97 71 32 136 216 149 185 148 202 94 106 117 327 476 492 159 109 163 87 85 46 170 362 340
Endoplasmic Reticulum 5 5 2 15 35 22 31 43 31 12 24 20 62 48 33 7 3 7 15 8 10 25 60 41
Endosome 1 0 0 3 3 1 0 5 4 2 1 4 0 1 1 1 0 0 1 0 2 2 5 3
Golgi 0 0 0 3 8 10 4 0 5 4 0 7 1 2 0 9 2 10 3 3 2 1 10 7
Mitochondria 9 10 0 3 10 42 88 108 172 105 182 139 0 0 0 4 5 7 4 4 6 8 13 5
Nucleus 0 0 0 0 0 0 2 0 0 0 0 1 0 1 4 2 0 0 0 0 0 0 1 0
Nuclear Periphery 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0
Vac/Vac Membrane 0 3 0 11 7 4 17 27 24 26 7 44 8 5 5 32 3 18 3 10 5 8 11 9
Unique Cell Count 103 83 34 172 271 217 299 303 384 226 290 304 383 520 525 203 125 194 120 115 76 223 478 419
Labelled Cell Count 113 92 35 189 301 245 363 375 474 271 355 371 410 542 552 227 136 217 120 115 76 223 478 419


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.0 9.3 10.6 11.0 10.3 9.0 8.4 8.6 8.0 7.6 7.1 7.4 12.6 13.1 12.9 14.1 15.3 15.7 11.7 12.2 12.5
Std Deviation (1e-4) 1.5 2.8 1.4 1.7 1.5 1.6 1.7 1.7 1.7 1.5 1.4 1.5 1.7 2.0 2.0 3.1 3.2 2.8 1.8 1.9 1.9
Intensity Change (Log2) – – – 0.05 -0.05 -0.24 -0.34 -0.31 -0.42 -0.48 -0.59 -0.52 0.24 0.3 0.28 0.4 0.52 0.56 0.14 0.2 0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -2.1 -2.0 -3.1 -3.7 -5.0 -4.7 -5.7 -6.4 -6.2 -1.4 -0.5 -0.1 -2.2 -1.1 -1.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 1.6 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.8 3.7 4.2 5.1 5.1 7.0 5.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.1661 6.7768 5.6104 5.1447 5.0012 5.3822 3.9353 7.2797 6.2894 4.873 4.4356 6.3865 4.5841 7.0579 6.0253 5.6797 5.7039 6.3932
Actin 0.0092 0.0058 0.0169 0.0321 0.0019 0.0116 0.0126 0.0102 0.0063 0.0015 0.0061 0.0031 0.0229 0.0012 0.0099 0.0022 0.0006 0.0064
Bud 0.0012 0.0009 0.0029 0.0072 0.0009 0.0007 0.0009 0.001 0.0013 0.0005 0.0004 0.0009 0.0012 0.0029 0.0011 0.0018 0.0005 0.001
Bud Neck 0.0008 0.0004 0.0052 0.0012 0.0006 0.001 0.0006 0.0004 0.0006 0.0005 0.0006 0.0011 0.0018 0.0004 0.0005 0.0008 0.0005 0.0016
Bud Periphery 0.0008 0.0003 0.0015 0.0113 0.0011 0.0008 0.0005 0.0003 0.0005 0.0003 0.0002 0.0007 0.0011 0.001 0.0005 0.002 0.0002 0.0009
Bud Site 0.0027 0.0024 0.0204 0.0025 0.0012 0.0004 0.0029 0.0038 0.0041 0.0006 0.0004 0.0004 0.0041 0.0052 0.0018 0.0006 0.0003 0.0003
Cell Periphery 0.0007 0.0002 0.0004 0.0004 0.0002 0.0003 0.0007 0.0002 0.0002 0 0.0001 0.0002 0.0004 0.0001 0.0002 0.0005 0 0.0003
Cytoplasm 0.4294 0.6869 0.4796 0.3782 0.2648 0.4834 0.5303 0.7135 0.6033 0.3162 0.4666 0.5484 0.3881 0.6888 0.4798 0.3712 0.4785 0.4301
Cytoplasmic Foci 0.0728 0.0567 0.0635 0.0589 0.0642 0.0713 0.0843 0.0559 0.0605 0.0531 0.0567 0.0543 0.0885 0.06 0.0673 0.0598 0.0487 0.0644
Eisosomes 0.0004 0 0.0004 0.0001 0 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0.0002 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0202 0.0064 0.0131 0.0319 0.0427 0.0177 0.0222 0.0094 0.0071 0.0027 0.0038 0.0201 0.0499 0.0062 0.0097 0.0216 0.0073 0.0244
Endosome 0.2842 0.1848 0.2542 0.3094 0.481 0.2925 0.2205 0.1539 0.2317 0.4829 0.3153 0.2363 0.2968 0.1807 0.3275 0.3845 0.3779 0.3239
Golgi 0.0782 0.0257 0.0584 0.0327 0.0444 0.0444 0.0533 0.0311 0.046 0.0446 0.0899 0.063 0.0636 0.0347 0.0495 0.0552 0.0463 0.0999
Lipid Particles 0.0112 0.0002 0.0055 0.0145 0.0048 0.0056 0.0144 0.0003 0.0031 0.0248 0.0123 0.0126 0.007 0.0002 0.004 0.0004 0.009 0.0005
Mitochondria 0.039 0.0098 0.0293 0.009 0.0228 0.0266 0.0132 0.0068 0.0135 0.0128 0.022 0.04 0.0245 0.0066 0.0139 0.0408 0.0067 0.0292
None 0.0041 0.0017 0.0205 0.0026 0.0008 0.0103 0.0043 0.0018 0.0014 0.0007 0.0007 0.0008 0.0037 0.0015 0.0009 0.0007 0.0004 0.0014
Nuclear Periphery 0.0069 0.001 0.0014 0.0082 0.0144 0.0102 0.0066 0.0012 0.001 0.0018 0.0017 0.0006 0.0139 0.0006 0.0025 0.0027 0.0017 0.0015
Nucleolus 0.0005 0 0.0005 0.0001 0.0003 0.0001 0.0001 0.0001 0 0.0002 0 0.0002 0.0002 0 0.0001 0 0.0001 0.0001
Nucleus 0.0057 0.0009 0.0009 0.0017 0.0023 0.0027 0.0022 0.001 0.0006 0.001 0.0006 0.0004 0.0018 0.0006 0.0008 0.0009 0.0007 0.0006
Peroxisomes 0.0075 0.0003 0.0042 0.0186 0.001 0.0023 0.0123 0.0004 0.002 0.0078 0.0013 0.0052 0.0055 0.0003 0.0017 0.0003 0.0006 0.0004
Punctate Nuclear 0.0021 0.0002 0.0008 0.0028 0.001 0.002 0.0016 0.0008 0.0002 0.0011 0.0003 0.0006 0.0046 0.0001 0.0005 0.0001 0.0002 0.0006
Vacuole 0.015 0.0109 0.0129 0.0611 0.0303 0.0096 0.0119 0.0051 0.0104 0.0278 0.0138 0.0058 0.014 0.0057 0.0181 0.0337 0.0109 0.0065
Vacuole Periphery 0.0072 0.0044 0.0074 0.0154 0.0194 0.0062 0.0044 0.0028 0.0061 0.0192 0.0073 0.0051 0.0062 0.0033 0.0096 0.0202 0.009 0.0062

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.1483 28.5446 20.3969 22.0469 22.2335 29.5497 23.5167 23.0869 28.9981 22.2578
Translational Efficiency 2.0967 1.4336 1.6589 2.2264 1.6317 1.3465 1.8258 1.6258 1.4141 1.7689

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
270 669 2599 167 1795 1617 257 1203 2065 2286 2856 1370

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1103.14 1281.58 1123.40 1414.86 1086.85 1156.11 1458.26 1367.85 1088.98 1192.83 1153.53 1373.58
Standard Deviation 156.22 186.71 154.20 178.41 174.44 180.74 174.90 198.93 172.26 191.23 183.23 197.15
Intensity Change Log 2 — 0.216308 0.026256 0.359043 — 0.089126 0.424095 0.331757 — 0.154590 0.237375 0.345566

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000368 0.000369 0.000968 0.003479 0.000198 0.000397 0.002394 0.001427 0.000220 0.000389 0.001096 0.001678
Bud Neck 0.000800 0.000303 0.000681 0.003264 0.000309 0.000330 0.004045 0.001762 0.000373 0.000323 0.000984 0.001945
Bud Site 0.058036 0.038443 0.038048 0.149220 0.026906 0.036830 0.088302 0.066893 0.030976 0.037302 0.042570 0.076928
Cell Periphery 0.000704 0.000478 0.001075 0.008545 0.000444 0.000386 0.001037 0.000867 0.000478 0.000413 0.001072 0.001803
Cytoplasm 0.213456 0.211303 0.300910 0.359504 0.295044 0.276291 0.277908 0.475373 0.284376 0.257272 0.298840 0.461249
Cytoplasmic Foci 0.508842 0.485493 0.250734 0.189279 0.420314 0.440319 0.295225 0.189168 0.431889 0.453539 0.254738 0.189181
Eisosomes 0.000020 0.000012 0.000034 0.000035 0.000014 0.000017 0.000022 0.000013 0.000014 0.000015 0.000033 0.000016
Endoplasmic Reticulum 0.006744 0.007362 0.006198 0.009050 0.008220 0.005924 0.008301 0.002257 0.008027 0.006345 0.006387 0.003085
Endosome 0.040054 0.032094 0.046019 0.042782 0.025662 0.028822 0.076835 0.035378 0.027544 0.029779 0.048792 0.036281
Golgi 0.093601 0.157317 0.125789 0.082138 0.089066 0.132898 0.065337 0.066125 0.089659 0.140044 0.120349 0.068077
Lipid Particles 0.000879 0.001327 0.005463 0.019447 0.000889 0.001596 0.011317 0.006380 0.000888 0.001518 0.005989 0.007972
Mitochondria 0.003608 0.002319 0.005002 0.000083 0.006401 0.004840 0.000042 0.001253 0.006036 0.004102 0.004555 0.001110
Mitotic Spindle 0.000890 0.004575 0.001843 0.006440 0.001137 0.002387 0.014254 0.007350 0.001105 0.003027 0.002960 0.007239
None 0.000069 0.000109 0.000102 0.000057 0.000804 0.000187 0.000036 0.000058 0.000708 0.000164 0.000096 0.000058
Nuclear Periphery 0.000017 0.000023 0.000052 0.000036 0.000035 0.000032 0.000122 0.000226 0.000032 0.000029 0.000058 0.000203
Nuclear Periphery Foci 0.000243 0.000415 0.000614 0.002858 0.000364 0.000710 0.004686 0.001874 0.000348 0.000624 0.000981 0.001994
Nucleolus 0.000013 0.000010 0.000061 0.000046 0.000052 0.000041 0.000037 0.000101 0.000047 0.000032 0.000059 0.000094
Nucleus 0.000256 0.000157 0.000563 0.000752 0.000689 0.000308 0.001187 0.001356 0.000632 0.000264 0.000619 0.001282
Peroxisomes 0.000515 0.000476 0.000917 0.002639 0.000281 0.000421 0.001835 0.002174 0.000312 0.000437 0.001000 0.002230
Vacuole 0.018015 0.013435 0.111016 0.100071 0.029550 0.016204 0.124904 0.107698 0.028042 0.015394 0.112266 0.106768
Vacuole Periphery 0.052871 0.043978 0.103909 0.020275 0.093623 0.051060 0.022175 0.032269 0.088294 0.048988 0.096555 0.030807

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.02 -2.21 -5.49 -5.50 -4.02 -4.37 -8.24 -3.14 -2.63 1.91 -4.49 -3.60 -4.12 -3.64 -1.40
Bud Neck 3.70 0.84 -6.23 -7.87 -6.84 -0.75 -10.97 -14.05 -13.86 6.11 1.66 -10.23 -15.21 -15.85 -8.82
Bud Site 3.79 4.22 -6.81 -8.68 -8.83 -5.32 -9.83 -13.70 -9.60 3.40 -3.67 -6.67 -14.60 -12.37 -10.66
Cell Periphery 2.94 -3.48 -3.36 -3.46 -3.19 1.23 -4.02 -4.78 -5.82 1.14 1.59 -7.16 -4.34 -4.58 -2.28
Cytoplasm 0.13 -5.81 -5.68 -6.28 -2.67 1.99 0.72 -16.46 -18.11 -10.77 3.30 -1.91 -17.39 -20.66 -16.65
Cytoplasmic Foci 1.48 18.50 17.30 19.59 4.66 -2.54 9.86 31.35 34.47 8.27 -3.10 27.85 35.25 41.10 11.75
Eisosomes 2.44 -3.24 -2.26 -3.65 -0.14 -2.35 -3.63 0.47 2.55 3.76 -0.89 -5.82 -1.00 -0.25 5.22
Endoplasmic Reticulum -0.31 0.37 -0.89 -0.61 -1.30 2.40 0.08 7.77 5.06 3.51 1.87 2.09 6.75 4.45 5.46
Endosome 2.32 -1.83 -0.51 -2.67 0.95 -2.41 -10.29 -5.44 -3.25 8.26 -1.90 -15.74 -5.12 -3.64 7.89
Golgi -8.88 -5.42 1.45 8.76 5.81 -11.63 4.90 7.10 16.44 0.04 -15.25 -9.43 7.20 19.80 14.82
Lipid Particles -1.85 -8.72 -5.66 -5.52 -4.24 -1.49 -6.30 -9.32 -6.48 2.68 -1.83 -10.23 -10.70 -8.78 -2.62
Mitochondria 0.66 -0.71 1.86 4.71 14.22 1.66 8.92 6.41 5.03 -2.98 2.39 2.03 6.64 5.36 7.50
Mitotic Spindle -2.51 -2.82 -2.28 -0.70 -1.88 -2.98 -4.96 -4.40 -3.48 2.19 -3.66 -4.78 -4.80 -3.21 -3.29
None -1.56 -2.37 0.75 2.09 3.64 2.15 2.67 2.59 5.89 -2.98 2.18 2.45 2.59 6.19 4.87
Nuclear Periphery -0.87 -4.78 -3.75 -1.89 2.07 0.34 -4.70 -1.72 -1.75 -0.91 0.50 -3.85 -1.75 -1.78 -1.48
Nuclear Periphery Foci -2.04 -4.56 -4.94 -4.58 -4.20 -1.64 -7.60 -4.00 -2.90 4.20 -1.73 -5.30 -4.83 -3.89 -2.98
Nucleolus 1.23 -15.67 -3.67 -3.95 1.56 0.44 0.69 -1.95 -2.46 -2.90 0.71 -0.60 -2.10 -2.91 -2.14
Nucleus 3.35 -2.16 -5.23 -6.33 -1.25 2.25 -2.58 -3.08 -4.17 -1.90 2.50 0.00 -3.25 -4.43 -3.29
Peroxisomes 0.28 -4.89 -6.38 -6.17 -5.18 -3.78 -7.26 -10.46 -9.55 -1.21 -2.71 -11.21 -11.72 -10.63 -7.09
Vacuole 1.46 -22.13 -6.74 -7.25 0.77 6.57 -9.28 -17.50 -21.04 1.19 7.15 -25.04 -18.78 -22.47 -0.02
Vacuole Periphery 1.56 -9.08 5.92 6.30 22.84 10.95 14.46 16.64 7.03 -2.20 11.62 -2.09 17.39 8.00 22.30
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
Localization
Cell Percentages cytoplasm (94%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-5

Dos2

Dos2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dos2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available