Standard name
Human Ortholog
Description Inositolphosphotransferase; involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid; can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.95 0.98 0.97 0.95 0.87 0.8 0.79 – 0.64 0.63 0.55 0.99 0.99 1.0 0.94 0.95 0.94 0.64 0.76 0.52 0.59 0.69 0.67
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.09 0.05 0.15 0 0.15 0.07 0 0.05
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.25 0.37 0.32 – 0.55 0.54 0.64 0 0 0 0.07 0 0 0.1 0.09 0.19 0.21 0.11 0.08
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 2 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 9 8 18 6 14 26
Bud 1 3 1 0 0 8 12 10 – 14 28 16 0 1 0 0 1 0 2 2 4 7 24 35
Bud Neck 2 2 5 0 2 0 4 7 – 2 2 2 6 4 3 1 2 2 4 4 7 2 14 19
Bud Site 0 0 0 0 0 1 0 3 – 2 3 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 2 2 5 4 0 3 3 – 0 1 2 3 0 2 1 1 0 3 5 8 9 28 19
Cytoplasm 385 384 520 310 385 498 505 523 – 391 350 315 658 406 796 221 285 181 306 324 291 279 693 667
Endoplasmic Reticulum 3 10 1 1 0 3 0 0 – 0 0 1 0 0 1 12 28 10 69 15 85 34 41 47
Endosome 4 1 0 3 8 5 3 1 – 1 0 3 1 1 0 2 4 4 4 4 7 4 4 8
Golgi 1 0 1 2 0 0 0 0 – 0 0 0 0 0 0 2 1 1 1 0 0 1 1 0
Mitochondria 3 13 1 7 6 140 231 210 – 336 296 364 1 0 0 17 6 5 50 36 103 99 114 80
Nucleus 0 0 0 1 0 2 2 3 – 4 3 0 1 2 2 0 4 1 0 0 0 1 0 3
Nuclear Periphery 0 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4
Nucleolus 0 0 0 0 1 0 1 1 – 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 1 1 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 2 0 3 3 8 17 – 15 17 18 2 0 0 2 0 0 5 2 4 2 12 17
Vac/Vac Membrane 5 0 4 1 17 4 13 5 – 10 4 11 1 0 0 3 6 7 12 11 12 18 35 51
Unique Cell Count 400 406 529 318 406 570 632 664 614 552 572 663 409 798 236 301 192 478 426 556 473 1004 1003
Labelled Cell Count 406 417 537 330 426 664 783 785 776 705 738 673 414 804 261 338 211 478 426 556 473 1004 1003


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 4.1 4.4 4.0 3.9 2.9 2.7 2.9 – 2.5 2.6 2.6 5.2 5.3 5.3 4.9 5.3 5.7 5.6 5.4 5.8
Std Deviation (1e-4) 0.6 0.5 0.9 1.2 1.4 1.1 1.0 0.9 – 0.8 1.2 0.7 1.0 1.2 0.9 1.6 1.4 1.8 1.8 1.4 1.8
Intensity Change (Log2) – – – -0.11 -0.18 -0.58 -0.7 -0.58 – -0.79 -0.73 -0.73 0.26 0.28 0.28 0.17 0.27 0.37 0.35 0.31 0.4


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.5191 1.4064 1.1655 3.5936 1.8126 5.3484 3.809 3.9662 4.0635 4.2275 3.3121 4.4284 3.1236 4.0694 3.6263 3.9229 3.8397 3.675
Actin 0.0153 0.0007 0.0196 0.005 0 0.0009 0.0245 0.0002 0.0022 0.0065 0.0003 0.007 0.0002 0.001 0.0023 0.0002 0.0001 0.0003
Bud 0.0007 0.0014 0.0187 0.0007 0 0.003 0.0032 0.0013 0.0034 0.0007 0.0004 0.0012 0.0001 0.0012 0.0004 0.0001 0.0001 0.0001
Bud Neck 0.0064 0.0074 0.0002 0.0019 0 0.0005 0.0094 0.0002 0.0006 0.0172 0.0015 0.0008 0.0001 0.0005 0.0003 0.0002 0.0002 0.0005
Bud Periphery 0.0018 0.0009 0.0067 0.0007 0 0.0062 0.0046 0.0017 0.0084 0.0011 0.0002 0.0052 0.0001 0.0018 0.0006 0.0002 0.0001 0.0002
Bud Site 0.0241 0.011 0.014 0.0112 0 0.0006 0.0069 0.0049 0.0113 0.011 0.0007 0.0003 0.0003 0.0108 0.0025 0.0002 0.0002 0.0001
Cell Periphery 0.005 0.001 0.0004 0.0007 0 0.0007 0.0006 0.0005 0.0007 0.0007 0.0001 0.0002 0.0002 0.0005 0.0003 0.0002 0.0001 0.0001
Cytoplasm 0.0723 0.138 0.1701 0.0728 0.1454 0.2132 0.2352 0.3738 0.3335 0.3603 0.5415 0.3753 0.294 0.4559 0.3731 0.4463 0.292 0.4727
Cytoplasmic Foci 0.0942 0.061 0.0375 0.0574 0.1023 0.0487 0.0321 0.0119 0.0184 0.017 0.0503 0.0207 0.0203 0.0146 0.0137 0.012 0.0329 0.016
Eisosomes 0.0016 0.0003 0.0002 0.0002 0 0.0079 0.0003 0.0001 0.0002 0.0004 0 0.0001 0.0001 0.0001 0.0002 0 0.0001 0
Endoplasmic Reticulum 0.0349 0.0071 0.016 0.0201 0.0013 0.0084 0.0232 0.0148 0.0152 0.0216 0.0209 0.0104 0.0204 0.0151 0.0163 0.0198 0.0039 0.0157
Endosome 0.112 0.0639 0.0579 0.2018 0.0044 0.075 0.0258 0.0101 0.0194 0.0211 0.0413 0.0164 0.0051 0.0162 0.0086 0.0128 0.0147 0.0076
Golgi 0.0098 0.0028 0.004 0.0284 0.0003 0.0053 0.0053 0.0004 0.0007 0.003 0.0022 0.0038 0.0003 0.0004 0.0009 0.0002 0.0006 0.0002
Lipid Particles 0.0858 0.0093 0.0161 0.0636 0.0151 0.0221 0.0081 0.001 0.0024 0.0018 0.0009 0.0039 0.0025 0.0011 0.0023 0.0003 0.0032 0.0005
Mitochondria 0.0652 0.0115 0.002 0.1471 0.0007 0.0304 0.0029 0.0068 0.0008 0.0039 0.001 0.0012 0.0003 0.0004 0.0007 0.0002 0.0003 0.0003
None 0.3341 0.5165 0.6207 0.3112 0.7227 0.5023 0.5469 0.5529 0.5592 0.5086 0.3052 0.5397 0.645 0.4624 0.5667 0.4948 0.6374 0.4754
Nuclear Periphery 0.015 0.0035 0.0018 0.0021 0.0004 0.0065 0.0138 0.0022 0.0045 0.0048 0.0032 0.002 0.0017 0.0034 0.002 0.003 0.0011 0.0016
Nucleolus 0.0017 0.0097 0.0008 0.0011 0.0003 0.0007 0.0043 0.0007 0.0005 0.0015 0.0002 0.0002 0.0003 0.0003 0.0004 0.0001 0.0002 0.0001
Nucleus 0.0414 0.0055 0.0018 0.0009 0.0005 0.0032 0.0218 0.004 0.0033 0.0054 0.0036 0.0026 0.0014 0.0042 0.002 0.0029 0.0019 0.004
Peroxisomes 0.0533 0.0021 0.0025 0.0292 0.0036 0.0065 0.0055 0.0009 0.0009 0.0034 0.0064 0.002 0.0026 0.0001 0.0011 0 0.0034 0.0001
Punctate Nuclear 0.0035 0.0137 0.0018 0.0024 0.002 0.0032 0.0155 0.0011 0.0038 0.0036 0.002 0.002 0.0022 0.0016 0.0022 0.0009 0.0038 0.0013
Vacuole 0.018 0.1212 0.0061 0.0386 0.0008 0.0483 0.0081 0.0101 0.0094 0.0055 0.0169 0.0045 0.0026 0.0079 0.0031 0.0051 0.0033 0.0027
Vacuole Periphery 0.0039 0.0117 0.0009 0.0032 0.0001 0.0063 0.0018 0.0005 0.0013 0.001 0.0012 0.0005 0.0002 0.0006 0.0003 0.0005 0.0004 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 50.503 49.817 41.1251 50.1601 34.7718 55.6966 55.4069 53.5441 48.0245 53.9221
Translational Efficiency 0.6484 0.5452 0.6793 0.4645 0.6006 0.6824 0.6772 0.583 0.6487 0.5643

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
120 1121 248 1493 2419 1820 224 1677 2539 2941 472 3170

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 822.22 660.93 904.05 944.66 674.79 753.37 964.52 908.69 681.76 718.14 932.75 925.63
Standard Deviation 126.65 100.17 95.96 135.62 73.66 92.63 106.30 122.41 83.10 105.59 105.42 130.05
Intensity Change Log 2 — -0.315027 0.136878 0.200271 — 0.158920 0.515373 0.429350 — -0.081996 0.319851 0.308051

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001407 0.000227 0.000498 0.004291 0.000173 0.000688 0.000714 0.001320 0.000232 0.000512 0.000600 0.002719
Bud Neck 0.004081 0.017026 0.002472 0.011640 0.024275 0.034007 0.004819 0.012394 0.023320 0.027535 0.003586 0.012039
Bud Site 0.031592 0.006741 0.003396 0.035690 0.006972 0.014503 0.005386 0.026069 0.008135 0.011544 0.004340 0.030600
Cell Periphery 0.000465 0.000166 0.000414 0.001558 0.000320 0.000254 0.000722 0.000555 0.000327 0.000221 0.000560 0.001027
Cytoplasm 0.246965* 0.450332* 0.295235* 0.271291* 0.412441* 0.383698* 0.279024* 0.263434* 0.404621* 0.409096* 0.287541* 0.267134*
Cytoplasmic Foci 0.115112 0.232562* 0.045897 0.053618 0.221848* 0.268316* 0.051665 0.092013 0.216804* 0.254687* 0.048634 0.073930
Eisosomes 0.000198 0.000170 0.000145 0.000558 0.000479 0.000333 0.000218 0.000348 0.000465 0.000271 0.000180 0.000447
Endoplasmic Reticulum 0.004403 0.002974 0.011499 0.223792* 0.007090 0.002598 0.105205* 0.139402* 0.006963 0.002742 0.055969 0.179148*
Endosome 0.042080 0.023437 0.013762 0.016787 0.020071 0.031789 0.013556 0.040296 0.021111 0.028606 0.013664 0.029224
Golgi 0.033855 0.003006 0.000171 0.004136 0.006120 0.007222 0.000285 0.004374 0.007430 0.005615 0.000225 0.004262
Lipid Particles 0.006042 0.017959 0.010062 0.034512 0.033481 0.023763 0.020367 0.079764 0.032184 0.021551 0.014952 0.058451
Mitochondria 0.017552 0.005415 0.000415 0.001358 0.009165 0.013166 0.000290 0.002774 0.009561 0.010211 0.000355 0.002107
Mitotic Spindle 0.006370 0.001284 0.000877 0.011912 0.000809 0.005828 0.000446 0.013199 0.001072 0.004096 0.000672 0.012593
None 0.000695 0.007848 0.003124 0.001098 0.003260 0.002418 0.001236 0.003572 0.003139 0.004488 0.002228 0.002407
Nuclear Periphery 0.000704 0.001256 0.005315 0.006310 0.001160 0.000775 0.015667 0.012105 0.001139 0.000958 0.010227 0.009376
Nuclear Periphery Foci 0.002336 0.001598 0.013538 0.034038 0.000561 0.000515 0.064966 0.032919 0.000644 0.000927 0.037944 0.033446
Nucleolus 0.000467 0.003032 0.001424 0.000522 0.001755 0.001804 0.000417 0.001617 0.001695 0.002272 0.000946 0.001101
Nucleus 0.127396 0.130652* 0.436746* 0.074685 0.165217* 0.101486 0.196632* 0.067901 0.163429* 0.112603 0.322794* 0.071096
Peroxisomes 0.002598 0.006975 0.000787 0.001868 0.004980 0.011537 0.000679 0.003478 0.004868 0.009798 0.000736 0.002719
Vacuole 0.342859* 0.084913 0.153842 0.208315* 0.077892 0.092806 0.237513* 0.199853 0.090415 0.089797 0.193550 0.203838*
Vacuole Periphery 0.012824 0.002429 0.000383 0.002020 0.001930 0.002494 0.000195 0.002613 0.002445 0.002469 0.000294 0.002333

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.86 1.73 -3.55 -5.36 -4.80 -1.25 -8.44 -4.23 -1.27 -2.09 -1.12 -8.38 -6.48 -4.74 -5.24
Bud Neck -8.07 0.21 -7.88 2.94 -8.44 -4.37 13.91 7.60 10.16 -6.14 -2.38 15.53 8.47 10.50 -10.18
Bud Site 2.27 2.29 -0.68 -8.54 -7.39 -4.51 0.83 -6.93 -3.80 -7.33 -2.68 1.29 -9.75 -8.18 -10.16
Cell Periphery 3.83 0.02 -6.27 -8.66 -6.76 1.54 -5.96 -3.42 -4.14 1.89 3.24 -5.57 -7.96 -9.34 -5.03
Cytoplasm -8.39 -0.75 -0.94 16.78 -0.15 3.69 8.99 19.21 13.74 0.34 -0.38 12.23 21.33 21.02 0.17
Cytoplasmic Foci -11.11 5.44 4.53 28.74 -2.79 -7.36 29.69 27.21 30.98 -8.29 -7.24 36.38 34.23 42.91 -8.50
Eisosomes 0.74 1.10 -6.19 -6.78 -7.13 4.50 8.77 3.82 -0.07 -3.76 6.93 10.65 1.41 -4.80 -8.07
Endoplasmic Reticulum 1.05 -5.20 -24.50 -25.04 -23.48 6.61 -8.81 -21.02 -21.91 -3.81 6.62 -8.78 -31.93 -33.08 -16.38
Endosome 2.06 3.89 3.57 4.12 -1.42 -6.59 5.92 -10.62 -3.26 -14.77 -5.45 6.49 -5.85 0.27 -12.75
Golgi 2.40 2.71 2.35 -0.70 -5.89 -1.52 15.08 3.71 4.39 -9.42 2.05 11.85 4.91 3.53 -10.55
Lipid Particles -6.26 -2.59 -12.50 -6.53 -11.98 5.03 7.14 -12.12 -15.27 -16.29 6.22 10.98 -9.88 -15.98 -19.82
Mitochondria 1.09 1.78 1.68 5.60 -3.02 -2.70 10.22 7.04 8.54 -7.38 -0.68 10.03 8.08 10.12 -7.69
Mitotic Spindle 1.13 1.16 -1.98 -5.32 -5.35 -4.39 0.56 -6.55 -3.48 -6.81 -3.87 0.19 -8.29 -5.68 -8.56
None -5.40 -4.56 -1.34 5.05 3.49 1.18 3.46 -0.24 -1.06 -2.40 -1.82 2.25 1.46 2.79 -0.44
Nuclear Periphery -0.99 -7.94 -6.44 -6.00 -1.30 2.85 -5.95 -11.36 -11.81 0.75 1.26 -7.72 -12.68 -12.97 -0.13
Nuclear Periphery Foci 1.74 -6.37 -16.23 -17.04 -7.37 0.55 -12.02 -16.88 -16.91 5.04 -2.89 -12.96 -24.30 -24.05 0.79
Nucleolus -4.26 -5.46 -1.36 3.58 2.29 -0.60 4.97 0.26 0.82 -4.90 -1.91 2.89 1.54 3.35 -1.57
Nucleus -0.11 -11.05 2.59 9.71 18.99 14.50 -2.92 23.10 7.85 9.84 12.53 -12.09 24.14 11.94 19.58
Peroxisomes -6.03 3.31 0.84 7.17 -4.90 -7.50 14.99 3.60 9.09 -8.08 -7.79 15.07 6.63 11.70 -9.36
Vacuole 10.27 5.83 4.69 -21.34 -3.16 -4.07 -12.16 -23.12 -19.46 3.27 0.34 -13.32 -27.19 -28.85 0.30
Vacuole Periphery 1.56 1.99 1.70 1.14 -2.69 -2.76 14.85 -1.24 0.13 -5.79 -0.50 8.09 0.54 1.03 -5.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Inositolphosphotransferase; involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid; can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin
Localization
Cell Percentages cytoplasm (28%), ER (5%), mixed (46%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ipt1

Ipt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ipt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available