Standard name
Human Ortholog
Description Component of transport protein particle (TRAPP) complex III; TRAPPIII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating endosome-Golgi traffic and required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0
Cytoplasm 0.86 0.93 0.94 0.92 0.9 0.79 0.8 0.8 0.69 0.7 0.58 0.68 0.97 0.98 0.98 0.84 0.95 0.83 0.63 0.75 0.69 0.53 0.52 0.59
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0.08 0 0 0.1 0.16 0.11
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0.05 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0.08 0 0 0.05 0.24 0.22 0.14 0.44 0.42 0.52 0.29 0 0 0 0 0 0 0.07 0.09 0.19 0.17 0.16 0.13
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0.22 0 0.08 0 0.1 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 11 2 2 10 11 1 11 9 4 3 1 7 0 0 0 1 1 0 9 1 3 5 10 8
Bud 2 5 2 1 8 11 17 10 25 25 33 17 3 6 4 0 0 0 1 1 0 2 5 5
Bud Neck 0 0 3 1 6 3 2 3 2 0 2 1 0 0 0 0 0 0 9 2 8 6 8 9
Bud Site 0 0 0 0 0 0 0 1 2 2 2 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 27 15 11 7 5 7 4 8 7 8 4 6 6 7 2 0 0 0 1 1 2 3
Cytoplasm 249 246 371 316 441 441 575 487 376 403 302 302 421 561 614 75 53 15 209 221 319 132 214 236
Endoplasmic Reticulum 9 7 14 4 11 7 10 13 5 2 2 6 5 3 4 5 2 0 27 4 8 26 66 44
Endosome 9 0 0 1 0 5 5 7 4 3 0 8 1 3 2 5 0 0 17 3 4 3 5 4
Golgi 2 0 0 0 0 0 1 0 0 0 0 0 0 1 0 2 0 0 7 0 1 2 4 0
Mitochondria 22 20 0 14 25 133 160 83 238 245 271 129 8 6 2 1 0 0 23 27 86 42 66 51
Nucleus 0 0 0 0 1 0 5 7 5 4 4 8 0 0 0 0 1 1 0 1 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 1 0
SpindlePole 1 0 0 2 1 2 8 13 2 1 1 8 0 0 0 0 0 0 3 1 0 0 2 1
Vac/Vac Membrane 1 3 0 5 3 19 8 25 6 10 31 11 2 1 3 4 1 4 13 23 19 24 19 25
Unique Cell Count 288 265 395 342 488 556 722 608 544 577 524 447 432 572 625 89 56 18 330 294 462 251 414 399
Labelled Cell Count 308 283 419 369 518 629 807 666 673 707 657 508 444 588 635 100 60 20 330 294 462 251 414 399


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.1 6.1 5.6 6.0 4.7 5.0 5.3 4.3 4.2 4.1 4.8 5.9 5.9 6.1 9.5 9.4 10.1 5.3 5.6 5.8
Std Deviation (1e-4) 0.7 0.8 0.6 0.8 1.2 0.7 0.9 0.7 0.7 0.7 0.8 0.8 0.9 0.8 1.0 1.9 2.0 1.7 0.9 1.4 1.2
Intensity Change (Log2) – – – -0.13 -0.02 -0.38 -0.29 -0.22 -0.5 -0.53 -0.58 -0.33 -0.05 -0.05 0.0 0.63 0.63 0.73 -0.19 -0.11 -0.07

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 2.6 2.1 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 2.3 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.4 -3.3 0 -5.9 -4.9 0 0 0 0 -4.5 -4.9 -5.2 0.3 0 0
Cytoplasm -0.8 -1.9 -6.3 -6.3 -6.1 -9.3 -9.2 -12.3 -9.5 2.5 3.4 3.7 -3.1 0.2 -1.8
Endoplasmic Reticulum -2.1 -1.1 0 -2.4 -1.3 0 0 0 0 -2.3 -3.5 -3.4 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.1 4.6 0 10.1 7.7 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 2.9 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 3.7 0 4.1 0 0 4.9 3.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.6082 0.8923 0.6501 0.4392 0.6353 0.8907 0.9901 1.4706 1.3807 1.2214 0.6736 1.2836 0.4729 1.0277 0.8078 0.5531 0.3469 0.8291
Actin 0.0225 0.0025 0.025 0.0031 0.0186 0.0099 0.0258 0.0021 0.002 0.0044 0.0097 0.0038 0.0168 0.0013 0.0136 0.0004 0.0321 0.004
Bud 0.0013 0.0015 0.0028 0.0086 0.0006 0.0004 0.0012 0.0007 0.0032 0.0017 0.0022 0.0018 0.0008 0.0004 0.0013 0.0003 0.0016 0.0003
Bud Neck 0.0131 0.0011 0.0018 0.001 0.0006 0.0036 0.002 0.0004 0.0005 0.0019 0.0013 0.0022 0.0064 0.0003 0.0018 0.0014 0.0009 0.0039
Bud Periphery 0.0019 0.0013 0.0027 0.0031 0.0006 0.0007 0.002 0.0003 0.0025 0.0009 0.0024 0.0014 0.0011 0.0002 0.0013 0.0002 0.0023 0.0003
Bud Site 0.021 0.015 0.0119 0.003 0.0008 0.0006 0.0057 0.0144 0.0043 0.0014 0.0114 0.0004 0.0102 0.0036 0.0072 0.0004 0.0023 0.0003
Cell Periphery 0.0015 0.0009 0.0016 0.0007 0.0002 0.0003 0.0009 0.0004 0.0003 0.0002 0.0003 0.0001 0.0016 0.0003 0.0006 0.0002 0.0004 0.0002
Cytoplasm 0.5696 0.6809 0.5766 0.5916 0.516 0.6904 0.6471 0.8094 0.7966 0.7833 0.739 0.7821 0.6725 0.7806 0.7459 0.7839 0.5534 0.8035
Cytoplasmic Foci 0.0537 0.0439 0.0695 0.0438 0.0531 0.0455 0.0649 0.0489 0.0333 0.0573 0.0545 0.0489 0.0675 0.0442 0.0487 0.0277 0.0923 0.0392
Eisosomes 0.0005 0.0002 0.0006 0.0002 0.0003 0.0002 0.0002 0 0 0 0.0001 0 0.0002 0.0002 0.0004 0 0.0003 0.0001
Endoplasmic Reticulum 0.0135 0.0065 0.0123 0.0067 0.0086 0.0121 0.0063 0.0032 0.0032 0.0032 0.0044 0.0047 0.018 0.0042 0.0087 0.0062 0.0093 0.0076
Endosome 0.0649 0.0465 0.1138 0.0936 0.0763 0.0754 0.0792 0.0423 0.0525 0.0655 0.0849 0.062 0.081 0.0567 0.0867 0.1434 0.1115 0.0681
Golgi 0.0081 0.0053 0.015 0.0043 0.0101 0.0094 0.0201 0.0042 0.0062 0.0249 0.0133 0.0058 0.0147 0.0068 0.0103 0.0027 0.0176 0.0064
Lipid Particles 0.0072 0.0007 0.0057 0.0046 0.0023 0.0054 0.0143 0.0006 0.0028 0.0005 0.0026 0.0062 0.0087 0.001 0.0016 0.0003 0.0039 0.0006
Mitochondria 0.012 0.0025 0.0141 0.0087 0.0061 0.0059 0.0083 0.0011 0.002 0.0047 0.0063 0.0058 0.0137 0.0016 0.0044 0.0006 0.0247 0.0026
None 0.1681 0.1753 0.1211 0.1783 0.2691 0.1178 0.091 0.0642 0.0757 0.0371 0.0368 0.064 0.0683 0.0908 0.0499 0.0127 0.1145 0.0538
Nuclear Periphery 0.0118 0.0017 0.005 0.0106 0.0215 0.0058 0.0054 0.0006 0.0006 0.001 0.0034 0.0006 0.0018 0.0007 0.0017 0.001 0.0021 0.0029
Nucleolus 0.0009 0.0002 0.0003 0.0058 0.0005 0.0003 0.0004 0.0001 0.0001 0.0001 0.0002 0.0001 0.0008 0.0001 0.0002 0 0.0003 0.0001
Nucleus 0.0049 0.0023 0.0023 0.0074 0.0034 0.0016 0.0019 0.001 0.001 0.001 0.0015 0.0008 0.0011 0.0009 0.0015 0.0008 0.0013 0.001
Peroxisomes 0.0068 0.0007 0.0016 0.0009 0.0006 0.0057 0.0133 0.0012 0.0039 0.0016 0.0185 0.0033 0.0042 0.0003 0.0014 0.0001 0.0123 0.0008
Punctate Nuclear 0.0081 0.0011 0.006 0.0028 0.0026 0.0017 0.0013 0.0006 0.0004 0.0008 0.0017 0.0005 0.0021 0.0004 0.0032 0.0001 0.0009 0.0007
Vacuole 0.0069 0.0087 0.0079 0.0165 0.005 0.0055 0.0076 0.0037 0.0076 0.0068 0.0043 0.004 0.0071 0.0046 0.0079 0.0132 0.0129 0.0023
Vacuole Periphery 0.0018 0.0013 0.0021 0.0046 0.0031 0.0017 0.0012 0.0007 0.0013 0.0017 0.0013 0.0013 0.0013 0.0008 0.0017 0.0043 0.0029 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.576 7.0556 6.9808 9.6673 12.621 9.466 11.8899 11.2348 12.2316 12.8962
Translational Efficiency 0.5916 0.6379 0.7309 0.453 0.4248 0.5528 0.5136 0.3892 0.4285 0.4791

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1960 601 265 1152 91 1248 1347 2006 2051 1849 1612 3158

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 752.54 920.52 1125.10 954.58 900.23 845.66 979.40 946.50 759.09 869.99 1003.35 949.45
Standard Deviation 80.76 127.13 159.09 108.81 92.79 116.25 117.14 125.69 86.83 124.92 136.17 119.87
Intensity Change Log 2 — 0.290681 0.580213 0.343098 — -0.090216 0.121605 0.072309 — 0.095746 0.348592 0.201933

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000278 0.001437 0.001933 0.002926 0.000740 0.001093 0.000772 0.000910 0.000299 0.001205 0.000963 0.001645
Bud Neck 0.015012 0.011360 0.004534 0.008837 0.005857 0.013805 0.005040 0.010927 0.014606 0.013010 0.004957 0.010165
Bud Site 0.019294 0.040885 0.025851 0.047349 0.017178 0.037902 0.017732 0.037876 0.019200 0.038872 0.019067 0.041332
Cell Periphery 0.000280 0.000184 0.000352 0.000127 0.000444 0.000188 0.000096 0.000066 0.000287 0.000187 0.000138 0.000088
Cytoplasm 0.389993 0.342324 0.528756 0.347444 0.323642 0.274996 0.598442 0.431248 0.387049 0.296880 0.586986 0.400678
Cytoplasmic Foci 0.376277 0.403484 0.095654 0.184650 0.401423 0.427373 0.118475 0.135868 0.377393 0.419608 0.114724 0.153663
Eisosomes 0.000271 0.000163 0.000052 0.000077 0.000255 0.000218 0.000039 0.000035 0.000270 0.000200 0.000041 0.000050
Endoplasmic Reticulum 0.003946 0.001806 0.005211 0.001436 0.003482 0.001818 0.002106 0.000759 0.003925 0.001814 0.002617 0.001006
Endosome 0.040048 0.058011 0.020112 0.052771 0.087748 0.080618 0.014935 0.042123 0.042165 0.073270 0.015786 0.046007
Golgi 0.040571 0.038175 0.001231 0.006685 0.042049 0.061467 0.000945 0.005021 0.040637 0.053896 0.000992 0.005628
Lipid Particles 0.012130 0.003305 0.005290 0.003451 0.012948 0.006574 0.003309 0.002412 0.012167 0.005512 0.003635 0.002791
Mitochondria 0.014248 0.004290 0.000154 0.001639 0.001450 0.013296 0.000325 0.002305 0.013680 0.010369 0.000297 0.002062
Mitotic Spindle 0.003548 0.005814 0.014771 0.015210 0.000404 0.005291 0.011378 0.050719 0.003409 0.005461 0.011936 0.037766
None 0.002773 0.000339 0.000667 0.000259 0.000313 0.000201 0.001412 0.001078 0.002664 0.000246 0.001289 0.000779
Nuclear Periphery 0.000114 0.000063 0.000913 0.000346 0.000265 0.000068 0.000580 0.000537 0.000120 0.000066 0.000635 0.000467
Nuclear Periphery Foci 0.000264 0.000289 0.019568 0.002721 0.001028 0.000288 0.003353 0.001390 0.000297 0.000288 0.006019 0.001876
Nucleolus 0.000601 0.000156 0.000176 0.000323 0.000904 0.000284 0.000305 0.000666 0.000614 0.000243 0.000283 0.000541
Nucleus 0.013989 0.004739 0.064177 0.011711 0.009320 0.004354 0.047419 0.015062 0.013782 0.004479 0.050174 0.013839
Peroxisomes 0.004174 0.007740 0.001138 0.012007 0.005154 0.010618 0.002662 0.008672 0.004218 0.009682 0.002412 0.009889
Vacuole 0.052413 0.067859 0.208621 0.297394 0.072963 0.050835 0.169895 0.248239 0.053325 0.056368 0.176261 0.266170
Vacuole Periphery 0.009777 0.007576 0.000840 0.002637 0.012431 0.008713 0.000779 0.004088 0.009894 0.008343 0.000789 0.003559

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.12 -6.30 -5.32 -1.88 -0.57 -1.55 0.03 0.24 2.51 0.34 -7.17 -6.96 -6.24 -0.40 -1.85
Bud Neck 2.92 11.18 6.98 2.87 -2.32 -6.69 0.94 -4.02 3.48 -6.33 1.66 11.90 6.39 4.59 -6.32
Bud Site -6.70 -2.39 -6.13 0.85 -3.29 -5.27 0.56 -2.73 3.72 -5.19 -10.00 1.36 -6.31 3.36 -6.96
Cell Periphery 3.10 -2.44 9.10 2.81 8.17 4.22 6.06 6.71 7.94 6.26 4.56 8.23 12.41 7.83 8.10
Cytoplasm 3.73 -5.08 3.90 -0.45 6.95 1.88 -9.08 -3.69 -14.70 13.47 11.18 -17.86 -0.90 -12.01 17.05
Cytoplasmic Foci -2.20 39.71 32.48 22.62 -9.63 -1.18 13.50 13.14 44.07 -1.61 -5.92 49.03 45.93 48.48 -6.19
Eisosomes 3.38 14.43 13.48 3.28 -0.86 0.92 5.80 6.04 11.40 3.16 3.53 16.37 16.23 10.64 0.02
Endoplasmic Reticulum 3.36 -2.78 6.14 1.28 8.44 1.55 1.52 2.99 2.50 7.85 3.93 2.97 7.61 2.75 9.91
Endosome -4.35 9.50 0.63 4.20 -6.17 0.57 6.25 4.58 14.09 -10.97 -10.94 16.90 3.78 13.93 -13.02
Golgi 0.96 26.69 20.79 11.26 -3.56 -2.24 4.96 4.66 21.98 -5.10 -5.23 27.33 24.29 24.44 -6.18
Lipid Particles 12.24 8.40 12.78 0.32 5.60 2.20 3.50 3.78 5.69 3.05 8.17 12.77 14.50 5.52 4.03
Mitochondria 6.99 12.76 11.48 3.24 -2.85 -7.37 4.04 -0.47 7.30 -5.66 2.19 12.69 11.45 7.90 -6.05
Mitotic Spindle -1.07 -3.24 -4.42 -2.89 0.51 -4.27 -7.32 -13.54 -11.24 -8.05 -1.60 -5.82 -12.50 -11.36 -6.73
None 4.09 3.69 4.20 0.27 2.83 0.87 -2.09 -2.72 -3.40 0.50 4.30 2.40 3.38 -3.14 1.02
Nuclear Periphery 2.82 -10.73 -6.32 -7.49 7.42 1.89 -3.97 -4.19 -12.48 0.04 3.03 -11.88 -12.79 -14.38 3.03
Nuclear Periphery Foci -0.69 -12.10 -4.96 -4.87 10.30 3.31 -6.78 -0.99 -4.72 6.02 0.00 -14.92 -6.86 -6.74 9.90
Nucleolus 2.90 2.70 1.94 -3.41 -2.89 0.84 0.76 0.12 -3.93 -3.94 1.99 1.47 -0.08 -4.26 -3.20
Nucleus 11.05 -9.49 -1.00 -9.61 9.29 2.97 -18.58 -6.14 -12.88 16.55 11.40 -21.74 -5.16 -15.53 19.57
Peroxisomes -4.76 8.56 -5.05 -1.35 -8.63 -4.44 2.75 -1.61 4.00 -7.72 -8.30 5.18 -6.09 2.63 -10.60
Vacuole -4.05 -15.02 -34.93 -29.55 -5.90 1.87 -10.42 -17.40 -39.70 -11.31 -1.64 -29.41 -51.30 -49.62 -14.29
Vacuole Periphery 2.27 16.94 12.00 5.93 -2.46 0.71 2.30 1.90 8.63 -4.43 2.22 16.65 11.86 10.63 -5.11
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of transport protein particle (TRAPP) complex III; TRAPPIII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating endosome-Golgi traffic and required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role
Localization
Cell Percentages cytoplasm (77%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-3

Trs85

Trs85


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Trs85-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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