Standard name
Human Ortholog
Description Catalytically inactive alanine transaminase; expression is repressed in the presence of alanine and repression is mediated by Nrg1p; ALT2 has a paralog, ALT1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.95 0.95 0.94 0.87 0.8 0.85 – 0.8 0.7 0.68 0.98 0.97 0.99 0.95 0.95 0.95 0.98 0.93 0.92 0.83 0.85 0.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.1 0.08 0.18 0.31 0.45 0.27 – 0.37 0.53 0.56 0 0 0 0 0 0 0 0 0 0 0 0.08
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2
Bud 0 0 0 0 1 5 7 7 – 10 15 20 1 0 1 0 1 0 0 0 0 0 4 9
Bud Neck 1 0 0 0 0 0 2 2 – 5 3 2 1 3 0 0 1 0 0 0 0 0 1 1
Bud Site 0 0 0 0 0 1 0 1 – 2 4 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 0 1 1 2 2 0 2 – 3 1 3 0 0 1 2 2 8 0 0 0 0 0 0
Cytoplasm 175 45 105 281 490 647 648 679 – 552 357 582 324 344 531 314 283 266 178 72 113 65 211 223
Endoplasmic Reticulum 0 0 0 0 0 1 2 0 – 0 0 2 2 0 1 14 14 13 0 0 2 1 1 3
Endosome 0 0 0 1 0 0 0 1 – 1 0 0 0 3 0 7 5 4 0 0 0 1 4 18
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 1 0 0 0 2 0 0 0 0 0 4
Mitochondria 2 2 11 23 92 228 365 213 – 256 270 477 0 0 1 10 8 2 2 1 1 2 4 25
Nucleus 1 2 1 1 3 3 6 5 – 1 2 3 2 0 3 0 2 1 0 0 0 0 2 2
Nuclear Periphery 0 1 0 0 1 0 4 0 – 0 3 2 0 0 1 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 0 3 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 2 12 – 13 9 15 0 1 0 2 6 1 0 0 0 0 3 12
Vac/Vac Membrane 0 0 0 5 7 8 3 2 – 6 1 1 6 10 9 8 10 14 0 0 2 2 8 10
Unique Cell Count 176 46 111 295 521 741 810 803 693 508 852 332 353 539 330 299 280 183 78 123 79 248 320
Labelled Cell Count 181 50 118 312 596 896 1039 927 849 665 1110 336 363 548 357 332 311 183 78 123 79 248 320


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 4.5 3.7 3.8 3.7 3.2 2.7 3.0 – 2.7 2.6 2.5 5.7 5.4 5.5 5.5 5.6 5.8 5.6 6.3 6.3
Std Deviation (1e-4) 0.6 0.6 0.4 0.8 1.1 0.8 1.0 1.0 – 0.8 1.2 0.7 1.1 0.8 1.1 0.9 1.0 1.0 1.1 1.5 1.7
Intensity Change (Log2) – – – 0.04 0.01 -0.18 -0.46 -0.29 – -0.46 -0.47 -0.53 0.64 0.57 0.57 0.58 0.61 0.67 0.6 0.78 0.78


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6914 2.7227 2.1013 1.5264 1.6846 2.0766 1.9342 3.5566 2.86 2.6263 2.6212 2.7881 1.1428 2.3097 1.7048 1.5978 2.035 1.2632
Actin 0.0005 0.0007 0.0006 0.0007 0.0014 0.0008 0.0415 0.0026 0.0004 0.0005 0.002 0.0118 0.0106 0.0003 0.0004 0.0159 0.0005 0.0001
Bud 0.0011 0.0013 0.0072 0.0003 0.008 0.0007 0.0002 0.0002 0.0001 0.0001 0.0005 0.0005 0.0003 0.0001 0.0004 0.0012 0.0001 0.0003
Bud Neck 0.0005 0.0007 0.0011 0.0007 0.0012 0.0023 0.0023 0.0025 0.0004 0.0005 0.0017 0.0055 0.0004 0.0002 0.0004 0.0005 0.0008 0.0013
Bud Periphery 0.0003 0.0003 0.0009 0.0002 0.0012 0.0002 0.0003 0.0001 0 0.0001 0.0002 0.0003 0.0002 0 0.0001 0.0004 0 0.0002
Bud Site 0.0014 0.0058 0.0018 0.0002 0.0021 0.0002 0.0006 0.0162 0.0005 0.0002 0.0005 0.0007 0.0057 0.0003 0.0003 0.0014 0.0001 0.0003
Cell Periphery 0.0001 0.0001 0.0001 0 0.0002 0 0.0002 0.0001 0 0 0 0.0001 0.0001 0 0 0 0 0.0001
Cytoplasm 0.6335 0.6906 0.6575 0.6807 0.6722 0.6353 0.6577 0.8034 0.7786 0.7261 0.7209 0.7917 0.7574 0.9129 0.8826 0.7799 0.7703 0.8638
Cytoplasmic Foci 0.0189 0.0076 0.0105 0.0251 0.0097 0.0182 0.0168 0.0051 0.0048 0.0048 0.0068 0.0086 0.0273 0.0044 0.0144 0.0439 0.0248 0.0031
Eisosomes 0 0 0 0 0 0 0.0006 0 0 0 0 0.0001 0.0002 0 0 0 0 0
Endoplasmic Reticulum 0.0038 0.0036 0.0026 0.0038 0.0041 0.003 0.0094 0.0019 0.003 0.0024 0.0041 0.003 0.0072 0.0084 0.0028 0.0032 0.0065 0.0026
Endosome 0.0059 0.0048 0.0044 0.0163 0.0049 0.0059 0.0091 0.0015 0.0014 0.0025 0.0035 0.0073 0.0245 0.0119 0.0116 0.082 0.0832 0.0076
Golgi 0.0004 0.0002 0.0002 0.0005 0.0001 0.0002 0.0033 0.0002 0.0001 0.0001 0.0003 0.0011 0.0066 0.0003 0.0016 0.0238 0.0066 0.0002
Lipid Particles 0.0008 0.0001 0.0002 0.0002 0.0001 0.0002 0.0034 0.0001 0.0001 0.0002 0.0001 0.0011 0.0106 0.0003 0 0.0078 0.007 0.0001
Mitochondria 0.0006 0.0005 0.0009 0.0009 0.0006 0.0006 0.0012 0.0002 0.0002 0.0004 0.0003 0.0005 0.0113 0.0002 0.0008 0.005 0.0007 0.0004
None 0.2774 0.1684 0.204 0.155 0.2067 0.2124 0.2076 0.136 0.153 0.2121 0.2363 0.1216 0.1109 0.0244 0.0444 0.0047 0.0027 0.0185
Nuclear Periphery 0.0051 0.0052 0.0045 0.006 0.0053 0.0052 0.0062 0.0014 0.0031 0.0028 0.0024 0.0039 0.0025 0.0038 0.004 0.0025 0.0054 0.0045
Nucleolus 0.0006 0.0005 0.0004 0.0003 0.0006 0.0006 0.0003 0.0001 0.0001 0.0002 0.0001 0.0002 0.0004 0 0 0.0001 0 0.0006
Nucleus 0.0407 0.1014 0.0898 0.0792 0.0628 0.0929 0.029 0.0256 0.0475 0.0428 0.0166 0.0333 0.0091 0.0294 0.0333 0.0171 0.0869 0.0648
Peroxisomes 0.0004 0.0002 0.0004 0.0007 0.0002 0.0005 0.0042 0.0002 0.0001 0.0002 0.0002 0.0034 0.0076 0 0.0003 0.0072 0.0013 0.0001
Punctate Nuclear 0.0064 0.0065 0.0115 0.0273 0.0173 0.0195 0.004 0.0018 0.006 0.003 0.0019 0.0041 0.0026 0.0009 0.001 0.0016 0.0019 0.0037
Vacuole 0.0015 0.0015 0.0012 0.0014 0.0011 0.0012 0.0015 0.0007 0.0006 0.0009 0.0012 0.001 0.004 0.0017 0.0012 0.0011 0.0007 0.0234
Vacuole Periphery 0.0003 0.0002 0.0002 0.0003 0.0002 0.0003 0.0007 0.0001 0.0001 0.0002 0.0002 0.0003 0.0004 0.0004 0.0003 0.0007 0.0004 0.0044

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 37.287 27.1836 28.8163 20.5548 27.6923 18.0904 24.5405 16.5632 18.3292 22.6336
Translational Efficiency 0.9962 1.0859 0.8591 1.1514 1.1278 1.6217 0.9182 1.0367 0.8627 0.8711

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1158 1233 335 738 1473 1618 1686 1613 2631 2851 2021 2351

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 627.63 732.93 1018.19 1103.96 733.42 690.43 1075.77 1047.35 686.86 708.81 1066.23 1065.12
Standard Deviation 78.78 110.70 118.93 157.78 91.21 88.06 155.27 145.51 100.73 100.72 151.38 151.76
Intensity Change Log 2 — 0.223761 0.698021 0.814702 — -0.087144 0.552658 0.514032 — 0.064581 0.621514 0.660495

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000060 0.000273 0.000483 0.003741 0.000081 0.000301 0.000194 0.001462 0.000072 0.000289 0.000242 0.002178
Bud Neck 0.009301 0.005774 0.004922 0.012343 0.003198 0.021921 0.003278 0.011088 0.005884 0.014938 0.003551 0.011482
Bud Site 0.003246 0.014633 0.004924 0.054297 0.002144 0.010183 0.003980 0.034115 0.002629 0.012108 0.004136 0.040450
Cell Periphery 0.000125 0.000499 0.000176 0.000198 0.000115 0.000109 0.000091 0.000144 0.000119 0.000277 0.000105 0.000161
Cytoplasm 0.546859* 0.623810* 0.373215* 0.211932* 0.630950* 0.515645* 0.457879* 0.420588* 0.593939* 0.562424* 0.443845* 0.355089*
Cytoplasmic Foci 0.193617* 0.117390 0.010917 0.040521 0.131375 0.209561* 0.006423 0.026257 0.158770 0.169699 0.007168 0.030734
Eisosomes 0.000109 0.000055 0.000041 0.000037 0.000059 0.000104 0.000016 0.000025 0.000081 0.000083 0.000020 0.000029
Endoplasmic Reticulum 0.000373 0.001118 0.005234 0.003720 0.000759 0.000971 0.001486 0.001706 0.000589 0.001034 0.002107 0.002338
Endosome 0.008372 0.007457 0.003334 0.012578 0.005129 0.013339 0.001008 0.012176 0.006556 0.010795 0.001394 0.012302
Golgi 0.001041 0.001182 0.000125 0.001137 0.002123 0.002186 0.000092 0.004042 0.001647 0.001752 0.000098 0.003130
Lipid Particles 0.006535 0.003115 0.001581 0.002967 0.003555 0.005872 0.000522 0.001394 0.004867 0.004679 0.000697 0.001888
Mitochondria 0.009127 0.001647 0.000494 0.000978 0.001166 0.004596 0.000572 0.003093 0.004670 0.003321 0.000559 0.002429
Mitotic Spindle 0.000298 0.001985 0.002680 0.399627* 0.000808 0.005823 0.012603 0.237128* 0.000584 0.004164 0.010958 0.288138*
None 0.005842 0.010435 0.005595 0.011951 0.004412 0.002519 0.008514 0.006890 0.005041 0.005942 0.008030 0.008479
Nuclear Periphery 0.000368 0.000344 0.001639 0.001381 0.000336 0.000360 0.000892 0.001177 0.000350 0.000353 0.001016 0.001241
Nuclear Periphery Foci 0.000369 0.001779 0.003371 0.007485 0.000680 0.000335 0.001182 0.004002 0.000543 0.000959 0.001545 0.005096
Nucleolus 0.001124 0.001833 0.000435 0.001893 0.000589 0.001221 0.000235 0.001164 0.000824 0.001486 0.000268 0.001393
Nucleus 0.173219* 0.158221* 0.502855* 0.151000* 0.178239* 0.143246* 0.473897* 0.162439* 0.176030* 0.149722* 0.478697* 0.158849*
Peroxisomes 0.003046 0.002624 0.000440 0.007371 0.001257 0.009499 0.000437 0.008071 0.002044 0.006526 0.000437 0.007852
Vacuole 0.036209 0.045125 0.077355 0.074521 0.032514 0.051133 0.026601 0.060477 0.034140 0.048535 0.035014 0.064886
Vacuole Periphery 0.000759 0.000701 0.000184 0.000322 0.000509 0.001075 0.000098 0.002562 0.000619 0.000913 0.000112 0.001859

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.33 -10.94 -3.34 -2.90 -1.89 -4.32 -7.47 -7.83 -5.16 -5.22 -6.98 -11.45 -6.26 -4.91 -4.28
Bud Neck 3.25 2.33 -7.94 -10.24 -8.74 -11.50 -2.13 -11.14 3.63 -9.46 -8.63 1.70 -12.46 -2.48 -13.40
Bud Site -5.03 -1.98 -13.00 -8.29 -11.33 -5.75 -3.08 -13.56 -8.36 -11.79 -7.51 -3.07 -18.41 -11.18 -16.35
Cell Periphery -3.89 -5.88 -7.27 2.90 0.36 0.83 1.66 -1.88 -3.35 -4.26 -3.75 -0.33 -5.42 2.78 -5.32
Cytoplasm -7.01 15.50 37.93 45.54 11.10 12.41 27.13 35.58 21.63 9.68 4.74 28.75 46.62 40.79 15.93
Cytoplasmic Foci 10.69 32.51 24.59 15.00 -7.05 -12.20 32.00 23.90 32.98 -11.01 -2.33 45.24 34.57 35.18 -13.36
Eisosomes 11.14 8.51 12.27 1.29 1.42 -9.45 13.36 6.15 15.44 -10.36 -0.77 20.66 13.80 14.14 -9.66
Endoplasmic Reticulum -8.87 -13.23 -11.30 -8.72 5.55 -0.43 -10.59 -12.13 -2.96 -0.47 -1.74 -17.06 -16.97 -6.43 1.35
Endosome 0.81 4.87 1.11 0.33 -3.50 -8.18 9.55 -1.89 5.93 -8.03 -5.82 11.53 -0.33 5.07 -9.65
Golgi -0.63 6.60 0.76 1.39 -10.04 -0.10 3.14 1.04 1.99 -4.25 -0.26 4.21 0.98 1.92 -5.43
Lipid Particles 5.94 8.04 5.14 -1.52 -5.35 -3.85 9.63 4.00 6.59 -11.47 0.36 13.68 7.10 5.90 -14.17
Mitochondria 3.56 4.12 3.82 1.62 -5.27 -4.95 1.07 -0.81 5.09 -3.57 1.33 4.19 3.36 5.06 -4.49
Mitotic Spindle -1.96 -2.00 -23.90 -23.73* -23.16* -3.39 -6.86 -28.07* -27.19* -24.95* -3.91 -7.21 -36.54 -35.84* -33.04*
None -3.80 1.84 -2.37 1.01 -3.82 3.52 -6.71 -9.44 -16.00 -4.39 -1.41 -5.47 -8.53 -7.00 -4.65
Nuclear Periphery 0.19 -16.08 -16.64 -16.60 -6.47 -0.64 -17.56 -21.37 -20.65 -10.70 -0.39 -21.91 -26.99 -26.51 -13.37
Nuclear Periphery Foci -7.74 -9.85 -10.19 -9.51 -8.22 4.69 -4.15 -10.29 -10.54 -9.00 -5.08 -6.88 -14.41 -13.96 -12.43
Nucleolus -1.71 6.00 -6.29 -4.84 -7.14 -5.52 -0.68 -8.52 -7.57 -8.18 -3.44 1.12 -10.32 -8.68 -10.35
Nucleus 2.07 -21.26 -0.69 -2.10 18.76 5.88 -41.85 -3.00 -8.29 36.17 5.80 -48.72 -3.04 -7.77 41.37
Peroxisomes 0.86 4.73 -0.19 -1.18 -5.81 -8.31 3.13 -3.78 5.51 -5.34 -6.77 5.43 -2.55 4.46 -7.11
Vacuole -3.92 -9.32 -14.18 -12.49 -2.06 -7.44 -4.19 -18.15 -13.41 -14.61 -8.15 -8.27 -22.87 -18.37 -14.99
Vacuole Periphery 0.66 7.48 6.78 7.16 -1.31 -3.70 6.84 -0.60 1.51 -2.36 -3.07 10.70 0.53 2.08 -2.54
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Catalytically inactive alanine transaminase; expression is repressed in the presence of alanine and repression is mediated by Nrg1p; ALT2 has a paralog, ALT1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (50%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Alt2

Alt2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Alt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available