Standard name
Human Ortholog
Description Protein of unknown function; ECM18 has a paralog, ICT1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0.07 0.07 0.06 0.08 0.07 0.05 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Cytoplasm 0.55 0.67 0.69 0.54 0.51 0.35 0.33 0.33 0.24 0.23 0.25 0.21 0.96 0.96 0.97 0.88 – – 0.16 0.27 0.08 0.27 0.27 0.22
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0.07 0.07 0.07 0 0.05 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Mitochondria 0.51 0.31 0.15 0.45 0.45 0.71 0.74 0.68 0.78 0.83 0.85 0.86 0 0 0 0.15 – – 0.58 0.47 0.63 0.47 0.47 0.48
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0.11 0.09 0.05 0 0.07 0.09 0.07 0.08 0 0.08 0 0 0 0 – – 0 0 0.05 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0.06 0.06 0 0.06 0.06 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 1 0 0 0 0 0 0 0 0 0 2 1 0 0 – – 3 8 14 11 13 23
Bud 4 5 7 7 9 27 29 23 31 20 18 11 2 0 0 0 – – 1 1 2 7 7 16
Bud Neck 1 1 5 1 4 4 2 3 3 1 0 3 2 13 2 0 – – 2 2 3 4 11 12
Bud Site 0 0 1 1 0 2 8 7 6 9 9 9 0 0 0 0 – – – – – – – –
Cell Periphery 0 2 2 3 1 0 4 1 1 1 1 1 1 2 1 1 – – 0 1 2 2 6 8
Cytoplasm 106 144 187 97 110 140 143 131 90 67 92 72 482 351 480 30 – – 39 68 28 119 153 132
Endoplasmic Reticulum 7 3 2 1 3 1 1 1 4 0 0 2 1 0 1 1 – – 3 1 11 2 2 5
Endosome 1 8 7 1 8 0 0 4 0 0 1 0 8 4 10 0 – – 17 17 27 19 26 33
Golgi 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 – – 1 0 4 0 2 3
Mitochondria 99 67 40 81 97 283 324 271 290 240 319 297 3 0 2 5 – – 143 120 240 205 263 289
Nucleus 0 0 0 0 3 2 3 5 7 5 5 3 0 3 0 1 – – 0 0 0 2 3 4
Nuclear Periphery 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 1 – – 0 0 0 2 0 2
Nucleolus 0 1 1 0 0 0 0 1 0 0 2 0 0 0 0 0 – – 0 0 0 2 1 2
Peroxisomes 0 0 8 2 1 1 2 2 0 0 0 1 2 3 3 0 – – 1 0 11 2 2 3
SpindlePole 5 3 31 16 10 14 29 34 25 23 14 26 4 2 1 0 – – 9 9 18 18 21 26
Vac/Vac Membrane 5 2 3 1 4 10 4 9 5 4 6 11 6 3 4 0 – – 15 15 7 25 32 27
Unique Cell Count 194 214 272 179 214 399 438 398 374 289 374 345 503 365 494 34 248 255 382 438 566 607
Labelled Cell Count 228 238 296 212 251 484 549 492 462 370 468 436 513 382 504 39 248 255 382 438 566 607


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 3.7 4.0 3.5 4.1 3.2 3.1 3.3 3.0 2.9 2.4 2.6 4.9 5.0 4.9 4.9 4.8 4.7 5.1 5.1 5.7
Std Deviation (1e-4) 0.4 0.6 1.2 1.3 2.0 1.8 1.6 1.6 1.3 1.1 1.0 1.0 0.9 0.8 1.1 1.3 2.3 1.1 1.2 1.1 1.7
Intensity Change (Log2) – – – -0.19 0.03 -0.32 -0.37 -0.31 -0.43 -0.5 -0.73 -0.63 0.28 0.31 0.26 0.28 0.25 0.21 0.34 0.33 0.48

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2931 2.0732 1.6591 2.0235 1.8314 1.9634 0.2944 0.0719 0.1494 -0.1081 -0.2514 0.1889 -1.4366 -0.9514 -1.2461 -0.7502 -1.1374 -1.0243
Actin 0.0104 0.0075 0.0062 0.0016 0.0335 0.005 0.0306 0.011 0.0164 0.0061 0.0296 0.017 0.0275 0.0113 0.0088 0.0042 0.0477 0.0186
Bud 0.0008 0.0115 0.0052 0.0037 0.0006 0.0027 0.0031 0.006 0.012 0.0037 0.0025 0.0027 0.0039 0.0027 0.0021 0.002 0.0009 0.007
Bud Neck 0.0034 0.0039 0.0176 0.0018 0.0398 0.0136 0.017 0.0011 0.0066 0.0167 0.0023 0.0104 0.008 0.0021 0.0027 0.0111 0.0008 0.0078
Bud Periphery 0.0028 0.0083 0.0105 0.0115 0.0013 0.0031 0.0105 0.0112 0.0256 0.0152 0.0088 0.0098 0.0096 0.0057 0.0049 0.0042 0.002 0.0085
Bud Site 0.0058 0.085 0.0167 0.0017 0.0068 0.0015 0.0127 0.0252 0.031 0.0104 0.0026 0.0021 0.0147 0.0249 0.0151 0.0039 0.0011 0.0013
Cell Periphery 0.0029 0.0031 0.0035 0.0006 0.0005 0.0014 0.0014 0.0017 0.0029 0.0017 0.0007 0.0021 0.0023 0.0016 0.0018 0.0008 0.0004 0.0007
Cytoplasm 0.111 0.1672 0.1221 0.1006 0.0736 0.153 0.0988 0.1445 0.131 0.1093 0.1352 0.1626 0.1008 0.1588 0.1404 0.1107 0.1614 0.1852
Cytoplasmic Foci 0.1068 0.1105 0.1001 0.0939 0.0772 0.1085 0.129 0.1241 0.1323 0.1768 0.1665 0.1507 0.185 0.1269 0.1066 0.1185 0.122 0.1631
Eisosomes 0.0021 0.0007 0.0014 0.0004 0.0006 0.0006 0.0006 0.001 0.0012 0.0008 0.0003 0.0004 0.0012 0.0012 0.0018 0.0002 0.0008 0.0005
Endoplasmic Reticulum 0.0067 0.0049 0.0026 0.0038 0.0063 0.0038 0.0082 0.0049 0.0053 0.0062 0.0043 0.0056 0.0034 0.0043 0.0054 0.003 0.0045 0.0034
Endosome 0.0572 0.0512 0.0421 0.0805 0.0472 0.0486 0.1436 0.0767 0.0832 0.1165 0.1124 0.0696 0.1072 0.1025 0.0806 0.084 0.0918 0.0864
Golgi 0.0114 0.0116 0.0127 0.0132 0.0136 0.0116 0.0215 0.0209 0.0236 0.0196 0.033 0.0164 0.0287 0.0168 0.0248 0.0126 0.0288 0.0199
Lipid Particles 0.0223 0.0067 0.0123 0.0059 0.0085 0.0181 0.0321 0.0102 0.0209 0.0073 0.0123 0.0126 0.0242 0.0064 0.0084 0.0152 0.0163 0.0135
Mitochondria 0.0361 0.0289 0.0819 0.0728 0.0389 0.0726 0.0656 0.0694 0.1235 0.1097 0.1609 0.0934 0.0584 0.0373 0.1012 0.091 0.0708 0.0781
None 0.5811 0.4584 0.5187 0.5715 0.6087 0.5166 0.359 0.4458 0.3319 0.345 0.2763 0.3851 0.365 0.4559 0.4669 0.4848 0.3976 0.3628
Nuclear Periphery 0.0018 0.0018 0.0032 0.002 0.0007 0.0013 0.0119 0.003 0.0028 0.0053 0.0018 0.0078 0.0013 0.0011 0.0017 0.002 0.0027 0.0028
Nucleolus 0.0034 0.0018 0.0019 0.0011 0.0004 0.0016 0.0046 0.0019 0.002 0.0014 0.0016 0.0013 0.0037 0.0014 0.0007 0.0011 0.0008 0.0006
Nucleus 0.0029 0.0039 0.0033 0.0025 0.0014 0.0022 0.0066 0.0036 0.0041 0.0025 0.0025 0.0044 0.0025 0.0017 0.0015 0.0033 0.0016 0.0058
Peroxisomes 0.0136 0.0128 0.0252 0.0112 0.0368 0.0229 0.0152 0.022 0.0254 0.0218 0.0207 0.028 0.0371 0.0228 0.0144 0.0127 0.0361 0.0202
Punctate Nuclear 0.0067 0.0044 0.0051 0.0075 0.0014 0.0041 0.0129 0.004 0.0045 0.0025 0.0036 0.008 0.0037 0.0013 0.0012 0.0048 0.0018 0.0068
Vacuole 0.0089 0.0137 0.0064 0.0091 0.0015 0.0055 0.012 0.0096 0.0104 0.0139 0.0163 0.0067 0.0096 0.0112 0.0068 0.0239 0.0073 0.005
Vacuole Periphery 0.0017 0.0023 0.0015 0.003 0.0007 0.0016 0.003 0.0021 0.0032 0.0078 0.006 0.0033 0.0022 0.0022 0.0022 0.0058 0.0028 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression – – – – – – – – – –
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression –
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2076 550 148 103 1422 1774 234 534 3498 2324 382 637

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 590.78 696.39 850.53 867.12 647.36 714.25 860.02 834.08 613.78 710.02 856.34 839.42
Standard Deviation 63.18 89.83 81.86 99.58 72.85 89.73 97.67 132.61 72.80 90.08 91.99 128.43
Intensity Change Log 2 — 0.237274 0.525741 0.553611 — 0.141861 0.409802 0.365618 — 0.188175 0.466286 0.458378

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000838 0.001307 0.001910 0.007911 0.000508 0.000789 0.000525 0.001336 0.000704 0.000912 0.001061 0.002399
Bud Neck 0.036816 0.050172 0.016360 0.009784 0.030555 0.058145 0.006719 0.020942 0.034271 0.056258 0.010455 0.019138
Bud Site 0.016800 0.039493 0.009376 0.053335 0.009350 0.024725 0.004663 0.036154 0.013771 0.028220 0.006489 0.038932
Cell Periphery 0.000362 0.000243 0.000374 0.000462 0.000264 0.000148 0.000226 0.000154 0.000322 0.000171 0.000283 0.000204
Cytoplasm 0.118760 0.104129 0.197908 0.184211 0.205224 0.101064 0.212084 0.320812 0.153909 0.101789 0.206592 0.298724
Cytoplasmic Foci 0.290823 0.305648 0.104920 0.182272 0.383268 0.293658 0.093084 0.131761 0.328404 0.296496 0.097669 0.139928
Eisosomes 0.000646 0.000207 0.000233 0.000336 0.000377 0.000222 0.000167 0.000112 0.000537 0.000219 0.000193 0.000148
Endoplasmic Reticulum 0.002247 0.000567 0.007222 0.011926 0.001542 0.000835 0.004078 0.002206 0.001960 0.000772 0.005296 0.003778
Endosome 0.027363 0.094411 0.016287 0.023739 0.039273 0.080549 0.016630 0.029635 0.032204 0.083830 0.016498 0.028682
Golgi 0.059858 0.060022 0.001072 0.003970 0.025547 0.059211 0.001395 0.005760 0.045910 0.059403 0.001270 0.005471
Lipid Particles 0.033719 0.011626 0.015763 0.015569 0.034290 0.012514 0.014751 0.003543 0.033951 0.012304 0.015144 0.005487
Mitochondria 0.305794 0.125857 0.001932 0.001289 0.092944 0.191645 0.001183 0.006421 0.219267 0.176076 0.001473 0.005591
Mitotic Spindle 0.001515 0.014433 0.003443 0.007161 0.005894 0.014515 0.008013 0.044693 0.003295 0.014496 0.006242 0.038624
None 0.002532 0.001549 0.002499 0.000563 0.003392 0.001251 0.005550 0.001611 0.002882 0.001322 0.004368 0.001442
Nuclear Periphery 0.000515 0.000264 0.002816 0.001170 0.001266 0.000491 0.002719 0.001634 0.000820 0.000437 0.002757 0.001559
Nuclear Periphery Foci 0.000287 0.000366 0.004516 0.006775 0.000532 0.000444 0.004455 0.002186 0.000387 0.000426 0.004479 0.002928
Nucleolus 0.001783 0.003423 0.004360 0.001312 0.002277 0.002155 0.004354 0.001545 0.001984 0.002455 0.004357 0.001507
Nucleus 0.029699 0.026651 0.486032 0.155614 0.077191 0.024748 0.526860 0.142717 0.049006 0.025198 0.511042 0.144803
Peroxisomes 0.046975 0.105389 0.017135 0.058782 0.047284 0.054899 0.005252 0.027286 0.047101 0.066848 0.009856 0.032379
Vacuole 0.015879 0.046887 0.104817 0.273017 0.034043 0.068145 0.085678 0.212652 0.023263 0.063114 0.093093 0.222413
Vacuole Periphery 0.006790 0.007352 0.001024 0.000801 0.004979 0.009846 0.001613 0.006842 0.006054 0.009256 0.001385 0.005865

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.76 -2.37 -2.29 -2.02 -1.65 -2.29 -1.80 -4.08 -2.64 -2.79 -1.83 -2.52 -3.68 -3.02 -2.03
Bud Neck -2.66 4.10 11.70 8.97 1.07 -7.85 7.59 4.58 11.15 -3.14 -7.62 8.46 7.97 13.07 -1.95
Bud Site -5.72 3.21 -1.61 0.57 -2.38 -8.75 1.34 -5.21 -1.07 -5.44 -8.48 3.85 -4.43 -0.40 -5.93
Cell Periphery 2.67 -0.42 0.00 -2.14 0.34 3.68 0.45 3.60 0.21 4.45 5.89 0.77 5.12 -0.61 5.44
Cytoplasm 1.59 -4.16 -3.04 -3.51 0.09 14.78 0.12 -6.18 -14.95 -4.84 10.73 -4.16 -10.48 -15.12 -5.08
Cytoplasmic Foci -1.50 14.44 10.20 10.07 -1.02 11.15 28.24 31.26 22.76 -1.56 5.33 29.34 31.04 25.18 -1.62
Eisosomes 11.82 10.35 8.63 -2.48 -1.22 2.97 3.61 5.00 8.39 4.45 10.59 10.62 13.20 6.35 4.60
Endoplasmic Reticulum 5.18 -6.26 -5.96 -7.18 -1.88 3.61 -5.06 -4.18 -8.09 3.29 5.63 -7.45 -5.63 -9.97 3.33
Endosome -10.98 4.86 3.81 11.97 -0.23 -12.17 6.33 5.48 16.36 -1.45 -18.86 7.04 4.77 19.52 -1.71
Golgi 0.15 26.05 24.05 13.09 -1.22 -11.03 13.21 11.44 20.71 -2.03 -4.92 28.17 24.99 24.17 -2.45
Lipid Particles 8.49 6.61 7.92 -0.31 1.17 9.93 5.73 14.95 10.93 3.66 13.92 8.17 20.35 8.69 4.97
Mitochondria 16.11 44.11 44.27 13.78 1.85 -12.99 18.40 17.31 31.84 -2.51 6.38 44.50 43.17 34.28 -2.24
Mitotic Spindle -5.05 -1.09 -2.27 1.19 -1.63 -4.27 -0.53 -4.87 -3.35 -3.70 -7.91 -1.11 -5.58 -3.14 -4.38
None 2.05 -0.17 4.90 2.49 4.12 3.05 -1.18 2.74 -0.85 2.99 4.09 -1.45 4.08 -0.06 3.67
Nuclear Periphery 1.99 -6.10 -5.05 -6.21 2.05 1.99 -2.20 -1.19 -4.97 1.70 1.83 -4.89 -4.41 -6.55 2.61
Nuclear Periphery Foci -0.99 -3.20 -4.87 -4.78 -1.33 0.55 -3.02 -5.43 -5.47 1.80 -0.42 -4.32 -7.55 -7.17 1.61
Nucleolus -1.83 -3.17 2.01 3.05 4.59 0.16 -1.98 1.92 1.44 2.50 -1.11 -3.05 1.71 2.61 3.71
Nucleus 0.48 -17.30 -7.55 -7.55 9.26 13.42 -20.66 -8.96 -15.27 15.42 9.65 -27.67 -14.05 -16.99 18.45
Peroxisomes -7.84 7.31 1.24 5.69 -1.66 -2.20 14.86 6.81 8.71 -4.28 -6.56 16.49 7.16 11.01 -3.61
Vacuole -7.76 -7.80 -13.31 -11.96 -8.41 -10.03 -7.09 -21.58 -18.32 -11.52 -15.52 -10.90 -25.85 -21.64 -14.03
Vacuole Periphery -0.45 13.61 14.90 6.86 2.60 -7.73 5.56 0.57 3.92 -1.94 -5.84 11.02 2.12 4.62 -2.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; ECM18 has a paralog, ICT1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (49%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Ecm18

Ecm18


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ecm18-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available