Standard name
Human Ortholog
Description Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.64 0.85 0.82 0.65 0.84 0.72 0.71 0.63 0.52 0.48 0.37 0.37 0.84 1.0 0.98 0.89 0.92 0.91 0.51 0.67 0.53 0.85 0.81 0.77
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.07 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.53 0 0.09 0.31 0.14 0.5 0.5 0.54 0.69 0.69 0.84 0.84 0 0 0 0.05 0 0 0.1 0 0.17 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Vac/Vac Membrane 0.07 0.17 0.1 0.18 0.08 0 0 0 0.05 0 0 0 0.19 0 0 0.05 0.06 0 0.2 0.14 0.1 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 5 1 4 4
Bud 0 0 1 0 0 0 3 4 3 1 7 7 0 0 0 0 0 0 2 4 0 0 7 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 3 1 0 2 1 1 3 2
Bud Site 0 0 0 0 0 0 0 1 3 1 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 1 0 1 0 0 0 2 1 0 0 0 0 0 4 0 4 0 0 0 0 1 0
Cytoplasm 70 250 121 85 111 96 110 189 103 115 74 74 152 450 365 254 167 188 64 229 88 159 260 247
Endoplasmic Reticulum 0 2 4 1 0 0 0 0 1 1 0 0 0 0 1 27 12 13 0 0 2 1 2 3
Endosome 0 2 1 4 2 0 0 2 1 1 0 0 3 0 1 13 4 4 2 6 2 0 4 3
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 4 3 0 0 1
Mitochondria 58 7 13 41 19 67 77 161 137 167 168 168 4 3 1 15 4 3 12 11 27 7 8 16
Nucleus 0 1 2 3 0 1 1 6 6 4 5 5 1 1 2 4 3 1 9 18 5 3 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 1 0 1 1 0 0 1
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 0 0 0 1 0 1 1 1 1 1 4 4 0 0 1 1 2 3 2 5 2 3 17 8
Vac/Vac Membrane 8 50 15 23 10 3 4 8 9 10 2 7 35 3 0 15 10 7 25 47 16 4 2 15
Unique Cell Count 110 295 148 131 132 134 154 299 198 242 200 200 181 452 371 286 181 206 125 341 167 188 322 320
Labelled Cell Count 136 314 158 158 143 168 196 372 266 305 261 267 195 457 372 334 205 228 125 341 167 188 322 320


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 4.3 4.0 3.9 4.2 3.2 3.2 3.2 3.2 2.6 2.8 2.8 4.4 4.2 4.1 5.1 5.9 5.5 4.0 4.2 4.9
Std Deviation (1e-4) 0.5 1.0 1.1 1.4 2.1 1.5 2.0 1.4 1.7 0.8 1.0 1.0 1.1 1.6 1.4 1.8 2.6 1.7 1.5 1.7 1.4
Intensity Change (Log2) – – – -0.04 0.04 -0.32 -0.35 -0.35 -0.35 -0.62 -0.54 -0.54 0.11 0.04 0.03 0.32 0.56 0.43 -0.0 0.04 0.26


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – -1.9 -1.6 -2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1006 0.2054 -0.0725 -0.4181 -0.3493 0.1089 1.7594 1.2963 1.4525 1.9003 1.6758 1.5408 2.5236 2.7459 2.3848 2.4899 2.5044 2.8269
Actin 0.0256 0.0002 0.0076 0.0003 0.0162 0.0148 0.037 0.0086 0.0135 0.0602 0.0454 0.0102 0.0134 0.0066 0.0024 0.0006 0.0167 0.0008
Bud 0.0006 0.0003 0.0057 0.0003 0.0002 0.0003 0.0014 0.0007 0.0003 0.0012 0.0002 0.0014 0.0004 0.0002 0.0003 0.0001 0.0004 0.0001
Bud Neck 0.01 0.0003 0.0007 0.0005 0.0024 0.0017 0.0044 0.0002 0.0004 0.0021 0.0005 0.0034 0.0109 0.0017 0.0012 0.0003 0.0003 0.0006
Bud Periphery 0.0012 0.0021 0.0034 0.0004 0.0002 0.0005 0.0017 0.0012 0.0004 0.0047 0.0002 0.0036 0.0015 0.0001 0.0004 0 0.0013 0.0001
Bud Site 0.0044 0.0011 0.0038 0.0002 0.0006 0.0002 0.0155 0.0039 0.0055 0.0039 0.0007 0.0003 0.0015 0.0187 0.0012 0.0001 0.0002 0.0001
Cell Periphery 0.0004 0.0009 0.0003 0.0001 0.0001 0.0001 0.0005 0.0001 0.0001 0.0005 0 0.0001 0.0004 0.0003 0.0001 0 0.0001 0
Cytoplasm 0.1337 0.1917 0.139 0.2036 0.1697 0.1819 0.1343 0.1458 0.1024 0.1296 0.0761 0.1726 0.0898 0.1226 0.0982 0.1568 0.107 0.1449
Cytoplasmic Foci 0.041 0.0049 0.0088 0.0026 0.0065 0.0164 0.0545 0.0051 0.0177 0.0267 0.0545 0.0155 0.0133 0.0028 0.0178 0.0103 0.0051 0.006
Eisosomes 0.0004 0.0001 0.0005 0.0001 0.0003 0.0002 0.0004 0.0002 0.0001 0.001 0.0001 0.0002 0.0003 0.0007 0.0002 0.0001 0.0005 0.0001
Endoplasmic Reticulum 0.0056 0.0032 0.003 0.0022 0.0021 0.0027 0.0046 0.0024 0.0018 0.0017 0.0019 0.0034 0.005 0.004 0.0021 0.0009 0.0052 0.0015
Endosome 0.0216 0.0028 0.0083 0.0024 0.0039 0.0108 0.0347 0.0014 0.0118 0.024 0.0025 0.009 0.0057 0.0013 0.0046 0.001 0.008 0.0021
Golgi 0.0085 0.0001 0.0029 0.0001 0.0034 0.0024 0.01 0.0002 0.0083 0.0253 0.0012 0.0043 0.0011 0.0003 0.0004 0.0001 0.0032 0.0002
Lipid Particles 0.0231 0.0008 0.0048 0.0002 0.0065 0.0061 0.0155 0.0005 0.0077 0.0221 0.002 0.0031 0.0047 0.0005 0.0011 0.0001 0.0013 0.0042
Mitochondria 0.0173 0.0012 0.0076 0.0008 0.0023 0.0027 0.0092 0.0006 0.0042 0.0179 0.0013 0.0014 0.0012 0.0003 0.0006 0.0004 0.0057 0.0006
None 0.5127 0.5934 0.5806 0.568 0.6422 0.5695 0.5033 0.7127 0.7188 0.4456 0.6449 0.6328 0.8083 0.7707 0.7941 0.6866 0.7609 0.7265
Nuclear Periphery 0.0193 0.0055 0.0113 0.012 0.0063 0.0097 0.0284 0.0073 0.0057 0.0065 0.0054 0.0073 0.0098 0.0043 0.0023 0.0015 0.0201 0.0032
Nucleolus 0.0041 0.0021 0.0025 0.0019 0.0016 0.0023 0.0026 0.0018 0.0011 0.0022 0.0009 0.0016 0.0014 0.0008 0.0012 0.0021 0.002 0.001
Nucleus 0.1252 0.1759 0.1734 0.179 0.1113 0.152 0.08 0.0892 0.0788 0.0649 0.0974 0.1036 0.0139 0.054 0.0563 0.1244 0.0365 0.0881
Peroxisomes 0.0167 0.0002 0.0054 0.0001 0.0049 0.0042 0.0251 0.0014 0.0088 0.1227 0.0188 0.0021 0.0015 0.0002 0.0008 0.0004 0.0006 0.0044
Punctate Nuclear 0.0221 0.0105 0.0225 0.0232 0.0178 0.0191 0.0314 0.0157 0.0102 0.0324 0.0436 0.0218 0.013 0.0091 0.013 0.0139 0.0216 0.0145
Vacuole 0.0047 0.0025 0.0052 0.0015 0.001 0.0018 0.0033 0.001 0.0019 0.0035 0.0022 0.0015 0.0021 0.0006 0.0014 0.0003 0.0013 0.0007
Vacuole Periphery 0.0016 0.0002 0.0028 0.0003 0.0002 0.0008 0.0021 0.0001 0.0004 0.0013 0.0002 0.0005 0.0007 0.0001 0.0002 0.0001 0.0021 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.1907 1.9887 5.4108 6.4622 3.8457 2.9645 5.362 5.4284 6.4937 6.3078
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2642 1819 1580 1921 259 2054 182 23 2901 3873 1762 1944

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 624.08 703.85 815.87 726.19 701.72 686.07 895.30 1150.21 631.01 694.42 824.07 731.21
Standard Deviation 66.49 83.15 96.91 84.25 79.44 83.91 87.96 111.23 71.27 84.02 99.02 96.24
Intensity Change Log 2 — 0.173537 0.386608 0.218616 — -0.032540 0.351476 0.712930 — 0.068139 0.368120 0.501104

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000049 0.000162 0.000158 0.000100 0.000040 0.000364 0.000280 0.000024 0.000048 0.000269 0.000171 0.000099
Bud Neck 0.011590 0.020919 0.003014 0.004668 0.000948 0.025898 0.001227 0.005947 0.010640 0.023559 0.002829 0.004683
Bud Site 0.005855 0.004325 0.003692 0.003775 0.000262 0.008115 0.001395 0.000474 0.005356 0.006335 0.003454 0.003736
Cell Periphery 0.000244 0.000098 0.000135 0.000083 0.000203 0.000131 0.000190 0.000014 0.000241 0.000116 0.000140 0.000082
Cytoplasm 0.439196* 0.350010* 0.175855* 0.290688* 0.316559* 0.321460* 0.147662* 0.331919* 0.428247* 0.334869* 0.172943* 0.291176*
Cytoplasmic Foci 0.052393 0.099777 0.006768 0.006606 0.120850 0.123410 0.018123 0.000621 0.058505 0.112310 0.007941 0.006536
Eisosomes 0.000075 0.000059 0.000032 0.000015 0.000110 0.000080 0.000100 0.000004 0.000079 0.000070 0.000039 0.000015
Endoplasmic Reticulum 0.000705 0.001311 0.002083 0.001141 0.000602 0.000954 0.004304 0.000330 0.000696 0.001121 0.002312 0.001131
Endosome 0.001326 0.005598 0.001161 0.001226 0.003891 0.008406 0.003841 0.000182 0.001555 0.007087 0.001438 0.001213
Golgi 0.000355 0.000945 0.000043 0.000128 0.000193 0.002851 0.000086 0.000018 0.000340 0.001955 0.000047 0.000127
Lipid Particles 0.002410 0.005028 0.001333 0.000578 0.007735 0.007600 0.003626 0.000063 0.002885 0.006392 0.001570 0.000572
Mitochondria 0.002033 0.008322 0.000798 0.001073 0.000540 0.018305 0.000434 0.000591 0.001899 0.013616 0.000760 0.001068
Mitotic Spindle 0.001927 0.003687 0.002188 0.005982 0.000008 0.009875 0.000342 0.000223 0.001755 0.006969 0.001997 0.005914
None 0.014073 0.005873 0.005873 0.004342 0.006352 0.006992 0.002636 0.004137 0.013384 0.006467 0.005539 0.004340
Nuclear Periphery 0.000729 0.001268 0.001754 0.001945 0.000745 0.001002 0.001679 0.001233 0.000730 0.001127 0.001746 0.001937
Nuclear Periphery Foci 0.000248 0.000429 0.000354 0.000326 0.000562 0.000388 0.001359 0.000007 0.000276 0.000408 0.000458 0.000322
Nucleolus 0.002602 0.003069 0.000838 0.000730 0.002173 0.004434 0.001130 0.000372 0.002563 0.003793 0.000868 0.000726
Nucleus 0.454317* 0.453916* 0.777040* 0.663764* 0.519800* 0.418765* 0.738675* 0.645668* 0.460163* 0.435274* 0.773077* 0.663550*
Peroxisomes 0.001019 0.005412 0.000241 0.000255 0.001330 0.015952 0.000388 0.000009 0.001047 0.011002 0.000256 0.000252
Vacuole 0.008431 0.028816 0.016477 0.012317 0.016672 0.023842 0.072275 0.008125 0.009167 0.026178 0.022240 0.012267
Vacuole Periphery 0.000423 0.000975 0.000166 0.000257 0.000425 0.001178 0.000247 0.000041 0.000423 0.001083 0.000174 0.000255

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.38 -6.02 -2.81 1.36 2.45 -4.79 -6.55 -1.87 3.50 4.49 -6.01 -7.18 -2.87 3.25 3.00
Bud Neck -5.35 8.36 4.45 8.79 -4.77 -14.30 -2.07 -2.53 -0.38 -2.45 -9.11 8.28 3.50 12.64 -5.46
Bud Site 1.55 1.94 1.07 -0.34 -0.92 -8.09 -3.98 -2.15 2.28 -0.98 -0.95 1.81 0.67 1.71 -1.11
Cell Periphery 12.06 8.10 11.56 1.48 4.34 4.77 0.48 11.40 13.43 8.79 11.44 8.00 12.06 3.53 5.18
Cytoplasm 11.85 38.77 21.08 7.94 -14.90 -0.26 9.10 2.46 2.74 -2.16 15.44 39.79 20.17 7.40 -15.63
Cytoplasmic Foci -12.17 24.25 23.73 25.63 -1.21 -0.10 11.81 13.79 30.10 4.75 -17.12 26.32 26.48 39.25 0.20
Eisosomes 2.26 5.96 9.55 15.29 7.82 4.38 -0.61 11.78 12.78 9.50 1.22 5.46 11.06 23.80 10.95
Endoplasmic Reticulum -4.45 -12.48 -6.42 -2.07 7.85 -2.61 -9.20 -1.41 0.27 8.47 -3.88 -14.70 -6.76 -4.12 9.73
Endosome -8.65 -0.57 -1.24 7.23 -0.95 -4.14 -0.26 3.36 9.71 4.79 -12.64 -0.85 -0.33 11.17 0.19
Golgi -2.84 5.15 2.60 3.95 -1.50 -6.69 2.62 0.21 6.64 -1.38 -6.85 5.33 2.57 7.74 -1.45
Lipid Particles -6.81 3.47 8.33 12.65 4.19 0.43 4.27 7.90 12.10 8.09 -8.71 4.64 10.66 16.10 5.85
Mitochondria -6.45 3.30 2.24 7.57 -0.90 -11.09 0.90 -2.22 10.15 -2.44 -11.69 3.35 2.03 12.61 -1.06
Mitotic Spindle -1.55 -0.01 -5.54 -4.38 -5.43 -6.41 -1.68 -1.42 -1.07 -1.40 -4.73 -0.04 -5.80 -3.22 -5.69
None 7.31 8.10 8.29 0.84 0.05 -0.55 5.54 -2.16 -1.99 -3.60 6.97 8.53 8.14 1.83 -0.56
Nuclear Periphery -2.96 -7.09 -9.32 -8.68 -2.50 -3.06 -7.93 -4.16 -3.83 -2.62 -2.62 -7.69 -10.00 -11.24 -2.87
Nuclear Periphery Foci -2.43 -3.06 -2.89 -2.42 -2.21 1.42 -4.94 2.48 1.62 6.62 -1.92 -4.41 -2.81 -2.47 -1.87
Nucleolus -1.45 5.10 -0.21 0.93 -3.79 -4.09 3.57 -1.63 -1.31 -1.79 -3.36 5.43 -0.52 2.08 -4.04
Nucleus 0.16 -40.57 -23.07 -20.52 14.66 5.26 -5.94 -1.41 -3.35 1.52 3.71 -39.89 -22.78 -26.23 13.80
Peroxisomes -10.16 5.40 4.47 12.02 -0.15 -10.83 2.90 3.02 12.44 0.78 -14.08 6.00 4.95 15.28 -0.06
Vacuole -13.77 -9.35 -8.72 4.25 1.63 -3.97 -8.11 -1.80 -1.54 2.02 -17.50 -11.71 -8.46 3.09 5.29
Vacuole Periphery -4.97 3.65 1.89 6.53 -0.93 -3.91 1.03 1.68 8.41 1.05 -6.98 3.77 1.98 8.50 -0.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (28%), nucleus (7%), mixed (61%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mrx16

Mrx16


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrx16-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available