Standard name
Human Ortholog
Description S-adenosylmethionine-dependent methyltransferase; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC; member of the seven beta-strand family
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.97 0.99 0.91 0.86 0.88 0.83 – 0.75 0.78 0.7 0.73 0.98 0.99 0.97 0.95 0.96 0.97 0.93 0.93 0.97 0.93 0.94 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.18 0.05 – 0.26 0.2 0.34 0.29 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.13 0.19 0.08 0.21 – 0.13 0.11 0.1 0.07 0 0 0.06 0.05 0.07 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 3 1 1 0 3 1
Bud 0 0 0 1 0 5 2 – 5 3 7 5 0 0 0 0 0 0 1 0 2 1 4 9
Bud Neck 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 1 5 1 5 – 9 10 1 3 0 0 2 9 10 11 0 0 0 0 0 0
Cytoplasm 460 486 568 488 473 465 694 – 574 633 268 334 494 600 724 282 288 266 442 474 546 337 526 597
Endoplasmic Reticulum 0 3 1 0 1 0 0 – 0 1 0 1 4 1 1 9 8 12 0 0 2 4 4 5
Endosome 1 1 1 2 1 0 3 – 2 4 1 2 0 0 3 2 0 0 5 4 0 3 1 2
Golgi 2 1 1 1 0 0 0 – 0 0 0 0 2 1 0 0 0 0 5 2 0 2 1 3
Mitochondria 1 7 0 11 16 94 45 – 197 159 132 134 0 1 0 0 3 1 4 8 2 0 4 4
Nucleus 1 4 3 3 5 6 17 – 15 16 12 11 1 0 0 6 3 3 2 3 0 0 1 2
Nuclear Periphery 1 0 0 1 1 0 0 – 4 3 0 2 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 1 0 0 – 2 1 1 0 0 0 0 1 0 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 2 0 4 – 1 1 1 0 0 0 0 0 0 0 0 1 0 2 3 3
Vac/Vac Membrane 10 5 17 71 102 40 174 – 97 89 37 30 18 16 41 15 21 13 0 5 0 3 3 2
Unique Cell Count 472 499 574 536 548 531 832 769 811 385 460 505 609 744 296 301 275 473 509 563 363 558 648
Labelled Cell Count 476 508 591 579 608 611 944 907 920 460 522 519 619 771 324 333 306 473 509 563 363 558 648


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.1 6.5 7.4 6.9 7.3 5.2 6.1 – 5.1 5.4 5.1 5.2 7.8 7.8 7.9 8.0 8.6 7.6 6.8 7.1 7.5
Std Deviation (1e-4) 0.9 0.9 1.1 1.3 1.5 1.3 1.3 – 1.1 1.0 1.0 1.1 1.2 1.2 1.4 1.1 1.4 1.2 1.3 1.6 1.6
Intensity Change (Log2) – – – -0.11 -0.03 -0.52 -0.29 – -0.56 -0.47 -0.54 -0.52 0.07 0.07 0.09 0.11 0.2 0.02 -0.14 -0.07 0.01

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -6.1 -8.2 -7.7 -9.4 – -12.4 -11.3 -13.3 -12.6 -1.5 -0.7 -2.1 -3.4 -3.2 -2.3
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.4 4.1 10.5 5.7 – 13.1 11.3 15.1 13.9 0 0 0 0 0 0
Nucleus 0 0 0 2.4 – 2.3 2.3 3.2 2.6 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 6.3 8.5 3.4 9.7 – 6.3 5.5 4.4 2.7 0.6 -0.3 2.2 1.6 2.8 1.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.1095 2.204 1.603 1.3634 1.3036 1.6782 3.7604 3.5685 3.5009 3.1483 2.6789 3.5743 5.2814 6.903 6.1165 6.0966 6.5024 6.2553
Actin 0.0081 0.0017 0.004 0.0033 0.0011 0.002 0.0593 0.0069 0.0123 0.0345 0.0001 0.0113 0.0022 0.0003 0.0013 0.0005 0.0036 0.0005
Bud 0.0053 0.0037 0.0107 0.0099 0.0004 0.0027 0.0018 0.0007 0.0028 0.0019 0.0001 0.0009 0.0002 0.0001 0.0005 0.0002 0.0028 0.0001
Bud Neck 0.0004 0.0005 0.0007 0.0006 0.0006 0.0023 0.0099 0.0004 0.005 0.0005 0.0002 0.0026 0.0008 0.0002 0.0003 0.0006 0.0162 0.0006
Bud Periphery 0.0022 0.001 0.0052 0.0098 0.0005 0.0021 0.0027 0.0003 0.0031 0.0024 0 0.0017 0.0001 0 0.0007 0.0001 0.0016 0
Bud Site 0.0049 0.0145 0.0063 0.0015 0.0002 0.0004 0.0141 0.006 0.014 0.001 0 0.0019 0.0009 0.0006 0.0026 0.0002 0.0025 0
Cell Periphery 0.0002 0.0002 0.0002 0.0004 0 0.0001 0.0007 0.0001 0.0004 0.0001 0 0.0002 0.0001 0.0001 0.0001 0 0.0001 0
Cytoplasm 0.7491 0.8185 0.7877 0.8038 0.8886 0.8342 0.5799 0.8457 0.831 0.6506 0.8905 0.8034 0.809 0.89 0.849 0.8994 0.7638 0.8843
Cytoplasmic Foci 0.0171 0.0163 0.0118 0.0159 0.0107 0.0146 0.0198 0.0057 0.0148 0.0372 0.0043 0.0134 0.0049 0.0029 0.0037 0.005 0.0087 0.0047
Eisosomes 0.0001 0 0 0 0 0 0.0005 0 0.0001 0.0003 0 0.0002 0 0 0 0 0.0001 0
Endoplasmic Reticulum 0.004 0.003 0.0036 0.0045 0.0032 0.0025 0.0198 0.0022 0.0028 0.0025 0.002 0.0018 0.0044 0.0015 0.0022 0.0044 0.0028 0.0019
Endosome 0.0069 0.0046 0.009 0.0104 0.005 0.0092 0.0312 0.0016 0.0122 0.0104 0.0018 0.0066 0.0041 0.0007 0.0016 0.0027 0.0016 0.0012
Golgi 0.0006 0.0002 0.0003 0.0002 0.0002 0.0002 0.0099 0.0003 0.0024 0.0097 0.0001 0.0027 0.0005 0.0001 0.0001 0.0002 0.0002 0.0001
Lipid Particles 0.0006 0.0002 0.0003 0.0002 0.0001 0.0002 0.0112 0.0002 0.0009 0.0179 0 0.0031 0.0008 0 0.0001 0.0001 0.0001 0
Mitochondria 0.0008 0.0004 0.0008 0.0008 0.0003 0.0004 0.0067 0.0002 0.0011 0.0446 0.0001 0.0023 0.0003 0.0001 0.0003 0.0002 0.0002 0.0001
None 0.1752 0.0832 0.1115 0.0844 0.0642 0.0771 0.1413 0.1209 0.0735 0.0755 0.0894 0.1243 0.155 0.0968 0.1295 0.0732 0.1853 0.0996
Nuclear Periphery 0.003 0.0045 0.0049 0.0047 0.0025 0.0032 0.0492 0.0011 0.0019 0.005 0.0012 0.0045 0.0029 0.0007 0.0011 0.0018 0.0011 0.0006
Nucleolus 0.0005 0.0006 0.0006 0.0018 0.0001 0.0005 0.0007 0.0001 0.0009 0.0002 0 0.0002 0.0006 0 0.0001 0 0.0002 0
Nucleus 0.0135 0.0288 0.028 0.0354 0.0168 0.0339 0.0112 0.0045 0.0109 0.0089 0.0091 0.0123 0.0047 0.0047 0.0052 0.0094 0.0051 0.005
Peroxisomes 0.0005 0.0003 0.0005 0.0002 0.0005 0.0002 0.0073 0.0006 0.0031 0.0922 0 0.0021 0.0004 0 0.0001 0.0001 0.0002 0.0001
Punctate Nuclear 0.0043 0.0154 0.0113 0.0088 0.0039 0.0123 0.0115 0.0017 0.0052 0.0024 0.0004 0.0031 0.0071 0.0006 0.0007 0.0009 0.0032 0.0008
Vacuole 0.0023 0.0021 0.0022 0.003 0.001 0.0018 0.006 0.0009 0.0013 0.0013 0.0004 0.0012 0.0008 0.0005 0.0007 0.0009 0.0005 0.0003
Vacuole Periphery 0.0003 0.0003 0.0004 0.0005 0.0002 0.0003 0.0052 0.0001 0.0003 0.0011 0.0001 0.0004 0.0002 0 0.0001 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.4785 42.9503 29.673 28.6528 22.5547 13.2468 29.9497 29.3103 31.1271 28.01
Translational Efficiency 1.0157 0.514 0.7425 0.7929 1.0202 1.9313 0.9231 0.7772 0.8935 0.8525

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
349 1640 165 2339 2105 1731 2096 1500 2454 3371 2261 3839

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 721.03 913.54 1016.14 976.70 770.66 913.43 979.70 1065.39 763.60 913.48 982.36 1011.35
Standard Deviation 100.20 132.13 110.87 149.32 101.18 109.80 127.01 153.36 102.51 121.18 126.26 157.00
Intensity Change Log 2 — 0.341409 0.494968 0.437856 — 0.245200 0.346246 0.467215 — 0.292505 0.420048 0.453099

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000618 0.000246 0.000667 0.000330 0.000098 0.000113 0.000198 0.000677 0.000172 0.000177 0.000232 0.000465
Bud Neck 0.008377 0.002439 0.002153 0.006142 0.004887 0.006439 0.003134 0.002106 0.005384 0.004493 0.003063 0.004565
Bud Site 0.023254 0.006049 0.005200 0.020307 0.004223 0.010272 0.021484 0.014599 0.006929 0.008217 0.020295 0.018077
Cell Periphery 0.000460 0.000107 0.000320 0.000079 0.000085 0.000055 0.000077 0.000092 0.000138 0.000080 0.000095 0.000084
Cytoplasm 0.532330 0.730799 0.430902 0.723234 0.666981 0.725242 0.730886 0.647873 0.647831 0.727946 0.708994 0.693788
Cytoplasmic Foci 0.187127 0.079911 0.028280 0.007417 0.113235 0.055055 0.007668 0.007799 0.123743 0.067147 0.009172 0.007566
Eisosomes 0.000109 0.000024 0.000101 0.000010 0.000043 0.000021 0.000009 0.000014 0.000053 0.000022 0.000016 0.000012
Endoplasmic Reticulum 0.006836 0.001669 0.007250 0.000608 0.000983 0.000364 0.000723 0.001100 0.001816 0.000999 0.001199 0.000800
Endosome 0.005692 0.004290 0.010266 0.001315 0.003943 0.002773 0.000840 0.002137 0.004192 0.003511 0.001528 0.001636
Golgi 0.001716 0.000782 0.000200 0.000697 0.000926 0.000690 0.000395 0.003619 0.001038 0.000735 0.000381 0.001839
Lipid Particles 0.003806 0.001293 0.004068 0.000339 0.002005 0.000529 0.000266 0.000526 0.002261 0.000901 0.000544 0.000412
Mitochondria 0.004512 0.000323 0.000223 0.000572 0.001065 0.000961 0.000528 0.000407 0.001555 0.000651 0.000506 0.000508
Mitotic Spindle 0.002128 0.001794 0.000634 0.018649 0.003078 0.007776 0.018052 0.023106 0.002943 0.004866 0.016781 0.020390
None 0.004540 0.006388 0.002353 0.008974 0.004850 0.004444 0.005824 0.012469 0.004806 0.005390 0.005571 0.010339
Nuclear Periphery 0.000534 0.000210 0.001582 0.000517 0.000316 0.000235 0.000532 0.000599 0.000347 0.000223 0.000609 0.000549
Nuclear Periphery Foci 0.001747 0.002278 0.011979 0.000930 0.000693 0.000261 0.000757 0.001549 0.000843 0.001243 0.001576 0.001172
Nucleolus 0.000694 0.000376 0.000369 0.000274 0.000610 0.000497 0.000332 0.000136 0.000622 0.000438 0.000334 0.000220
Nucleus 0.165860 0.119912 0.253085 0.160421 0.154439 0.138612 0.157034 0.230893 0.156063 0.129515 0.164044 0.187956
Peroxisomes 0.003077 0.001038 0.000381 0.000183 0.001329 0.000996 0.000222 0.000344 0.001577 0.001016 0.000233 0.000246
Vacuole 0.044825 0.039690 0.239713 0.048507 0.035379 0.044084 0.050851 0.049362 0.036722 0.041946 0.064634 0.048841
Vacuole Periphery 0.001757 0.000381 0.000274 0.000497 0.000832 0.000582 0.000188 0.000591 0.000963 0.000484 0.000195 0.000534

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 5.01 -1.82 2.41 -0.82 3.81 -0.84 -3.05 -3.70 -3.49 -3.10 -0.42 -1.91 -3.20 -3.06 -2.56
Bud Neck 4.63 4.26 2.39 -3.48 -2.85 -1.81 2.59 2.60 4.90 0.15 1.33 3.74 1.59 0.42 -2.35
Bud Site 4.89 4.67 3.39 -3.60 -2.99 -4.13 -5.64 -3.40 0.87 2.52 -1.25 -3.83 -2.82 -1.64 1.80
Cell Periphery 4.71 2.12 5.20 5.63 8.24 7.15 2.97 -1.88 -9.57 -4.49 4.93 4.40 5.07 0.23 0.72
Cytoplasm -13.29 7.81 -4.16 18.11 -12.22 -7.58 3.35 19.90 26.07 16.25 -12.65 3.72 14.07 29.81 9.01
Cytoplasmic Foci 9.84 15.63 17.45 24.58 5.44 15.05 33.50 33.63 20.85 0.92 15.51 36.80 37.66 32.09 3.01
Eisosomes 9.80 -0.08 10.62 4.26 12.14 10.19 17.05 10.78 -0.63 -9.87 13.84 15.03 15.70 3.16 0.82
Endoplasmic Reticulum 5.51 -1.48 6.63 3.69 9.52 3.76 1.04 -2.46 -11.08 -4.11 3.63 1.98 3.95 -0.32 1.96
Endosome 1.54 -2.89 6.53 6.42 8.47 2.84 10.81 8.06 4.75 -1.39 1.68 9.82 11.10 8.15 2.69
Golgi 2.99 5.00 4.42 3.31 -0.75 0.92 3.33 -0.00 -0.45 -1.33 1.60 4.28 1.84 0.74 -1.36
Lipid Particles 4.73 -0.04 6.18 5.10 8.86 8.16 9.09 5.00 -5.08 -7.08 7.58 9.33 8.77 1.53 -1.84
Mitochondria 2.52 2.55 2.40 -3.61 -6.43 0.44 2.72 3.00 2.68 0.82 3.01 3.58 3.63 1.49 0.13
Mitotic Spindle 0.08 -0.06 -6.98 -8.02 -7.44 -2.47 -6.91 -5.46 -2.89 1.06 -1.65 -6.99 -8.72 -7.15 0.23
None -1.15 1.85 -2.64 -2.67 -14.22 0.62 -1.36 -5.98 -6.61 -5.89 -0.71 -1.09 -6.71 -6.83 -7.89
Nuclear Periphery 1.62 -6.58 -3.35 -23.72 6.49 1.07 -12.38 -16.68 -16.43 -5.77 2.13 -12.82 -16.83 -25.78 -3.38
Nuclear Periphery Foci -1.34 -7.20 1.90 5.81 8.06 4.66 -0.14 -7.20 -12.28 -4.94 -3.31 -3.07 -4.23 -0.25 0.78
Nucleolus 2.78 3.55 4.46 1.67 0.66 0.85 2.01 3.12 3.18 1.59 1.49 2.35 3.23 3.35 0.92
Nucleus 4.82 -5.30 -5.07 -20.48 2.99 3.22 -8.93 -22.51 -24.58 -14.52 6.77 -9.87 -20.86 -30.42 -8.83
Peroxisomes 4.89 7.21 7.89 5.54 5.62 0.75 3.80 3.64 4.98 -0.40 1.73 5.17 5.28 7.58 0.53
Vacuole 0.95 -12.75 -14.07 -20.32 8.64 -4.21 -17.12 -20.64 -17.73 -6.51 -3.57 -19.66 -29.15 -26.82 -3.86
Vacuole Periphery 2.96 3.20 3.25 1.74 0.55 0.92 2.73 2.34 2.41 -0.54 2.04 3.57 3.16 2.94 -1.09
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description S-adenosylmethionine-dependent methyltransferase; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC; member of the seven beta-strand family
Localization
Cell Percentages cytoplasm (94%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Mtq2

Mtq2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mtq2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available