Standard name
Human Ortholog
Description Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p; N-terminally propionylated in vivo
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.99 0.97 0.97 0.92 – 0.88 0.79 0.79 0.68 0.78 1.0 0.99 0.99 – – – 0.87 0.87 0.77 0.87 0.85 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0.13 0 0.2 – 0.21 0.42 0.37 0.51 0.41 0 0 0 – – – 0 0 0.07 0.05 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 – – – 4 0 2 0 2 5
Bud 1 0 0 1 1 6 – 15 8 13 9 11 0 0 1 – – – 5 2 1 0 5 13
Bud Neck 3 1 1 0 3 4 – 22 2 7 3 3 0 0 0 – – – 2 0 0 0 3 4
Bud Site 0 0 0 0 0 0 – 0 0 1 1 7 1 0 0 – – – – – – – – –
Cell Periphery 3 0 0 3 0 0 – 0 2 1 2 3 1 0 1 – – – 2 0 1 2 2 3
Cytoplasm 595 148 178 226 271 365 – 570 308 343 255 422 532 661 744 – – – 508 134 108 167 383 432
Endoplasmic Reticulum 2 1 0 0 1 0 – 0 1 0 0 0 0 1 2 – – – 1 0 0 1 1 4
Endosome 0 0 0 0 0 1 – 1 0 0 0 0 0 0 1 – – – 3 1 1 1 3 7
Golgi 1 1 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 2 2 0 0 3 1
Mitochondria 12 4 3 31 9 79 – 136 164 158 190 225 2 2 0 – – – 22 6 10 8 20 21
Nucleus 1 0 0 0 0 0 – 2 1 0 0 3 0 0 1 – – – 0 0 0 0 0 1
Nuclear Periphery 1 0 0 0 0 0 – 1 0 0 0 1 0 1 1 – – – 0 0 0 0 0 1
Nucleolus 0 0 0 2 0 0 – 0 1 1 0 1 0 0 0 – – – 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 – – – 0 0 0 0 0 1
SpindlePole 1 0 0 1 5 3 – 24 4 6 5 14 1 2 0 – – – 6 0 1 1 4 13
Vac/Vac Membrane 0 0 0 0 1 4 – 1 1 0 1 2 0 0 0 – – – 7 3 2 2 10 16
Unique Cell Count 610 152 179 232 279 398 649 392 432 373 543 534 665 748 582 154 140 193 449 545
Labelled Cell Count 620 155 182 264 291 462 773 492 530 467 692 537 667 751 582 154 140 193 449 545


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.4 4.0 2.8 2.9 3.5 2.8 – 2.9 2.2 2.6 2.5 2.4 4.0 4.0 4.0 4.6 4.4 4.6 3.6 4.0 4.2
Std Deviation (1e-4) 0.6 1.0 0.7 1.7 1.8 1.3 – 1.3 0.8 1.0 0.9 0.9 1.4 1.1 1.3 1.3 1.1 1.7 0.6 1.2 1.8
Intensity Change (Log2) – – – 0.05 0.32 -0.0 – 0.06 -0.31 -0.11 -0.16 -0.2 0.53 0.55 0.53 0.72 0.66 0.74 0.38 0.51 0.62

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5464 -0.2754 -0.6241 -0.3826 -0.3272 -0.5999 -1.3787 -1.1759 -1.348 -1.6426 -1.495 -1.2122 -0.0987 0.1159 0.2791 0.4529 0.6906 0.177
Actin 0.0348 0.0151 0.026 0.0195 0.0324 0.01 0.0259 0.0003 0.0164 0.0003 0.0007 0.0021 0.0138 0.0031 0.0091 0.034 0.011 0.0324
Bud 0.0006 0.004 0.0004 0.0011 0.0003 0.0004 0.0004 0.0041 0.0008 0.0001 0.0002 0.0001 0.0004 0.0044 0.0009 0.0015 0.0133 0.0017
Bud Neck 0.0019 0.0004 0.0006 0.0005 0.003 0.0007 0.0027 0.0001 0.0018 0 0.0004 0.0002 0.0133 0.0002 0.0008 0.0045 0.0024 0.0013
Bud Periphery 0.0008 0.0035 0.0007 0.0056 0.0004 0.0008 0.0008 0.0007 0.0012 0.0005 0.0004 0.0003 0.0008 0.006 0.0019 0.0063 0.0148 0.0078
Bud Site 0.0039 0.0064 0.0077 0.0028 0.0014 0.0001 0.0043 0.0088 0.0127 0 0.0053 0.0001 0.0096 0.0111 0.0138 0.0017 0.0164 0.0006
Cell Periphery 0.0003 0.0002 0.0002 0.0002 0.0002 0.0001 0.0002 0.0001 0.0003 0 0.0001 0.0001 0.0004 0.0002 0.0002 0.0007 0.0007 0.0004
Cytoplasm 0.0308 0.0178 0.0212 0.0095 0.0365 0.057 0.0297 0.0363 0.0286 0.0098 0.0151 0.0483 0.0141 0.0295 0.03 0.0393 0.0107 0.043
Cytoplasmic Foci 0.031 0.0092 0.0174 0.0069 0.0232 0.0089 0.0284 0.006 0.0159 0.0063 0.0074 0.0073 0.0076 0.0011 0.0121 0.0187 0.033 0.005
Eisosomes 0.0006 0.0002 0.0004 0.0008 0.0003 0.0002 0.0006 0.0003 0.0004 0.0001 0.0001 0.0001 0.0003 0.0002 0.0002 0.0002 0.0002 0.0004
Endoplasmic Reticulum 0.0032 0.0005 0.0016 0.0015 0.006 0.0007 0.0024 0.0004 0.0011 0.0001 0.0006 0.0004 0.0006 0.0004 0.001 0.0014 0.0104 0.0009
Endosome 0.0086 0.0003 0.003 0.0167 0.0487 0.0019 0.0176 0.0003 0.0051 0.0002 0.0048 0.0043 0.0104 0.0005 0.0117 0.0153 0.0231 0.0044
Golgi 0.0037 0.0006 0.0015 0.0053 0.0171 0.0018 0.0062 0.0001 0.0038 0.0001 0.0016 0.0037 0.0056 0.0003 0.0025 0.0073 0.0114 0.0022
Lipid Particles 0.0092 0.0008 0.0021 0.0089 0.0351 0.0049 0.0151 0.0002 0.0032 0.0006 0.0072 0.0022 0.005 0.0001 0.0043 0.0106 0.0464 0.0018
Mitochondria 0.0112 0.0009 0.0011 0.0225 0.0106 0.0013 0.0037 0.0007 0.0121 0.0018 0.002 0.0059 0.0027 0.0014 0.0016 0.0027 0.003 0.0022
None 0.8187 0.9308 0.8979 0.8692 0.7086 0.89 0.8255 0.936 0.8825 0.9736 0.9344 0.9129 0.8961 0.9405 0.899 0.8251 0.7179 0.8867
Nuclear Periphery 0.009 0.0006 0.0015 0.0063 0.0256 0.0023 0.0052 0.0002 0.0005 0.0002 0.0024 0.0037 0.0008 0.0002 0.001 0.0009 0.007 0.0026
Nucleolus 0.001 0.001 0.0003 0.0015 0.0008 0.0004 0.0007 0.001 0.0004 0.0003 0.0009 0.0003 0.0014 0.0002 0.0004 0.0006 0.0014 0.0004
Nucleus 0.0057 0.0023 0.0008 0.0051 0.0047 0.0063 0.0015 0.0014 0.0004 0.0003 0.0012 0.0027 0.0043 0.0003 0.0008 0.001 0.0073 0.0013
Peroxisomes 0.0115 0.0008 0.0096 0.0045 0.0313 0.0096 0.0207 0.0003 0.0083 0.0036 0.0122 0.0023 0.0071 0.0001 0.0022 0.0232 0.0549 0.0018
Punctate Nuclear 0.012 0.0039 0.0054 0.009 0.0068 0.002 0.0041 0.0023 0.0033 0.0018 0.002 0.0023 0.002 0.0002 0.004 0.001 0.0055 0.0022
Vacuole 0.0011 0.0006 0.0003 0.0018 0.0028 0.0003 0.0033 0.0003 0.0008 0.0001 0.0007 0.0006 0.0031 0.0002 0.0019 0.0033 0.0073 0.0006
Vacuole Periphery 0.0006 0.0001 0.0001 0.0009 0.0043 0.0003 0.0009 0.0001 0.0004 0 0.0003 0.0003 0.0007 0.0001 0.0007 0.0006 0.0019 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1433.8727 1048.1792 139.4159 99.628 1077.4409 762.8347 558.0265 304.5096 250.5358 881.7015
Translational Efficiency 2.2165 2.0079 1.6007 2.6634 2.3982 3.2635 2.2362 2.2948 1.7935 2.3991

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1754 1233 304 1293 1286 1652 2432 1400 3040 2885 2736 2693

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 639.55 703.43 918.74 778.14 617.13 754.28 762.93 804.89 630.07 732.55 780.24 792.05
Standard Deviation 80.14 93.17 103.40 112.79 67.67 94.39 100.75 99.68 75.93 97.18 112.29 107.02
Intensity Change Log 2 — 0.137350 0.522599 0.282973 — 0.289526 0.305976 0.383217 — 0.214086 0.420277 0.333071

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000056 0.000272 0.000867 0.000783 0.000056 0.000794 0.000168 0.000818 0.000056 0.000571 0.000246 0.000801
Bud Neck 0.012663 0.021641 0.003826 0.010205 0.010404 0.028064 0.009934 0.007009 0.011707 0.025319 0.009255 0.008544
Bud Site 0.001653 0.006480 0.003612 0.036626 0.002858 0.008938 0.016013 0.036396 0.002163 0.007887 0.014635 0.036506
Cell Periphery 0.000106 0.000146 0.000202 0.000288 0.000278 0.000222 0.000117 0.000196 0.000179 0.000189 0.000126 0.000240
Cytoplasm 0.485055 0.437501 0.114221 0.399950 0.450126 0.365514 0.500020 0.438111 0.470279 0.396280 0.457154 0.419788
Cytoplasmic Foci 0.205846 0.230723 0.005709 0.033577 0.213834 0.222229 0.009718 0.034811 0.209225 0.225859 0.009273 0.034219
Eisosomes 0.000160 0.000131 0.000085 0.000082 0.000313 0.000189 0.000024 0.000065 0.000225 0.000164 0.000031 0.000073
Endoplasmic Reticulum 0.000474 0.000766 0.011244 0.002008 0.000407 0.000890 0.000873 0.001599 0.000445 0.000837 0.002025 0.001795
Endosome 0.010965 0.016683 0.003092 0.011788 0.005719 0.017666 0.001858 0.005608 0.008746 0.017246 0.001995 0.008575
Golgi 0.001188 0.002708 0.000112 0.006349 0.001154 0.003804 0.000210 0.001790 0.001174 0.003336 0.000199 0.003979
Lipid Particles 0.011396 0.007707 0.002800 0.002325 0.015336 0.008839 0.000625 0.001945 0.013063 0.008355 0.000866 0.002127
Mitochondria 0.003568 0.006335 0.000762 0.009190 0.005798 0.014168 0.001646 0.009547 0.004511 0.010820 0.001548 0.009376
Mitotic Spindle 0.000450 0.003752 0.004137 0.033805 0.000698 0.004563 0.026479 0.019417 0.000555 0.004216 0.023996 0.026325
None 0.005390 0.003027 0.004149 0.009777 0.004131 0.002667 0.005673 0.002923 0.004857 0.002821 0.005503 0.006214
Nuclear Periphery 0.000556 0.000610 0.002588 0.001987 0.000575 0.000663 0.001386 0.001727 0.000564 0.000640 0.001520 0.001852
Nuclear Periphery Foci 0.000281 0.000886 0.001477 0.001260 0.000179 0.000285 0.000230 0.000705 0.000238 0.000542 0.000369 0.000971
Nucleolus 0.002697 0.001733 0.001294 0.001290 0.001432 0.001784 0.000439 0.000448 0.002162 0.001762 0.000534 0.000852
Nucleus 0.206000 0.181637 0.791819 0.309178 0.255964 0.238438 0.388923 0.304482 0.227136 0.214162 0.433689 0.306736
Peroxisomes 0.005049 0.015003 0.000395 0.002879 0.005021 0.016624 0.001483 0.000671 0.005037 0.015931 0.001362 0.001731
Vacuole 0.045910 0.060557 0.047384 0.122225 0.025100 0.061819 0.033888 0.129695 0.037107 0.061280 0.035387 0.126108
Vacuole Periphery 0.000539 0.001702 0.000226 0.004428 0.000618 0.001840 0.000294 0.002040 0.000572 0.001781 0.000286 0.003186

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.69 -11.04 -4.40 -2.00 3.96 -1.95 -4.24 -2.87 0.60 -1.97 -2.43 -7.67 -4.75 0.14 -2.21
Bud Neck -4.89 6.17 3.67 7.38 -1.93 -8.70 0.25 3.78 11.50 3.68 -9.75 2.08 5.57 13.52 2.67
Bud Site -6.61 -2.90 -8.55 -6.56 -6.76 -4.37 -5.68 -6.74 -4.21 -3.03 -7.17 -7.02 -10.94 -7.47 -5.27
Cell Periphery -3.75 -6.64 -5.67 -3.04 0.35 1.52 5.95 4.37 2.79 -3.05 -0.53 4.53 0.35 0.89 -5.02
Cytoplasm 4.97 38.25 13.21 7.45 -23.50 8.69 1.57 8.63 0.37 7.92 10.76 9.71 15.78 5.11 5.19
Cytoplasmic Foci -3.17 42.17 36.39 32.28 -13.92 -1.01 37.73 33.57 34.52 -11.47 -2.96 55.95 49.51 47.20 -16.17
Eisosomes 1.86 3.78 5.63 8.09 2.65 2.81 6.54 5.49 11.87 -16.28 2.89 9.34 7.31 14.08 -15.56
Endoplasmic Reticulum -2.91 -13.58 -12.44 -9.61 11.49 -2.68 -12.14 -14.87 -7.48 -6.73 -3.56 -16.00 -19.18 -11.46 2.61
Endosome -3.65 8.51 3.25 6.02 -3.94 -9.24 8.78 3.67 10.95 -4.24 -8.26 13.35 5.13 11.83 -7.16
Golgi -3.04 7.06 -2.26 -0.61 -3.44 -4.65 6.77 1.23 4.94 -2.38 -5.54 9.34 -1.71 2.21 -3.97
Lipid Particles 3.60 10.29 11.58 8.38 2.40 5.04 12.22 11.13 13.84 -7.15 5.99 17.75 16.03 15.74 -9.38
Mitochondria -2.27 4.20 -1.07 0.65 -3.21 -3.88 3.17 0.77 4.54 -2.04 -4.99 4.42 -0.17 4.26 -3.39
Mitotic Spindle -2.95 -2.28 -7.58 -6.20 -3.95 -3.19 -10.81 -5.78 -3.64 4.48 -4.51 -11.33 -9.56 -7.11 2.16
None 2.50 2.43 -0.98 -3.03 -2.98 2.12 -2.36 2.83 0.02 8.17 3.34 -0.59 0.40 -2.73 1.05
Nuclear Periphery -0.58 -14.86 -12.15 -11.04 2.42 -2.00 -20.75 -11.86 -11.35 -2.34 -1.70 -25.60 -16.95 -15.89 -3.03
Nuclear Periphery Foci -1.60 -7.62 -5.12 -0.74 2.69 -1.53 -3.18 -6.82 -4.98 -5.73 -1.82 -6.18 -7.83 -2.51 -5.26
Nucleolus 1.73 3.09 3.51 2.43 1.21 -0.85 4.48 4.95 4.29 1.76 1.19 5.59 5.08 4.70 -1.29
Nucleus 3.19 -42.42 -14.21 -15.73 29.69 1.87 -20.32 -6.91 -8.90 12.25 2.09 -35.21 -15.51 -16.64 18.57
Peroxisomes -6.51 9.81 5.21 8.79 -2.72 -8.73 6.06 8.12 13.53 1.47 -10.92 8.57 9.50 15.69 -0.28
Vacuole -5.03 -4.23 -21.84 -18.21 -12.79 -14.01 -12.02 -29.78 -23.06 -24.67 -11.76 -8.23 -36.03 -29.28 -30.27
Vacuole Periphery -2.47 7.11 -3.37 -1.04 -3.89 -4.50 3.93 -1.09 2.40 -2.56 -4.81 6.65 -3.51 0.30 -4.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p; N-terminally propionylated in vivo
Localization
Cell Percentages cytoplasm (22%), nucleus (8%), mixed (31%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Hta1

Hta1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hta1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available