Standard name
Human Ortholog
Description U1 snRNP protein involved in splicing; required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0.06 0.05 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.07 0 0.06 0.09 0.05 0.05 0.05 – 0.05 0 0.05 0 0 0 0.06 0.06 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.07 0.31 0.31 0.33 0.63 0.71 0.67 – 0.67 0.76 0.77 0 0 0 0 0.07 0 0 0 0 0 0 0
Nucleus 0.91 0.91 0.92 0.85 0.83 0.76 0.71 0.69 – 0.66 0.67 0.64 0.91 0.92 0.93 0.9 0.88 0.87 0.82 0.78 0.75 0.82 0.78 0.72
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.09 0.13 0 0 0 0 0 0.07 – 0.05 0.05 0 0 0 0 0 0 0 0.08 0.07 0.13 0.06 0.08 0.09
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0 0.08 0.06 0 0.07 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 0 0 1 1
Bud 0 0 0 0 1 7 5 12 – 2 6 12 0 0 0 0 0 1 3 1 1 2 3 2
Bud Neck 0 0 0 0 0 0 1 1 – 0 0 0 2 0 0 0 0 0 0 0 1 0 1 1
Bud Site 0 0 0 1 1 15 15 11 – 32 25 24 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4 8 3 16 29 21 31 44 – 27 19 28 10 10 6 12 15 8 1 0 0 0 2 0
Endoplasmic Reticulum 0 1 0 0 0 0 0 0 – 0 1 0 3 2 1 2 6 3 0 0 0 2 0 3
Endosome 1 0 0 1 1 0 0 1 – 1 0 0 1 3 2 3 4 0 2 2 4 3 3 2
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 1 1 0 2 0 0 0 2 2
Mitochondria 10 9 73 89 106 277 422 557 – 341 391 438 8 6 13 7 17 3 2 2 1 0 2 0
Nucleus 197 109 215 241 269 334 421 573 – 336 347 364 243 254 309 175 223 133 183 102 180 148 240 241
Nuclear Periphery 0 0 2 3 0 3 2 2 – 5 1 2 0 0 0 0 0 0 1 0 0 0 1 1
Nucleolus 20 16 5 2 3 8 16 56 – 24 27 23 1 4 1 2 4 3 18 9 31 11 24 31
Peroxisomes 1 0 0 0 0 0 0 0 – 0 0 0 1 0 0 1 0 0 0 0 0 0 0 1
SpindlePole 0 0 3 0 0 6 7 10 – 9 1 6 10 6 6 4 2 3 0 1 2 3 2 7
Vac/Vac Membrane 3 3 3 3 6 3 4 4 – 3 7 3 2 1 4 5 13 8 7 10 14 6 21 35
Unique Cell Count 216 120 233 284 326 438 595 827 509 515 570 268 276 331 194 254 153 224 132 240 181 310 334
Labelled Cell Count 236 146 304 356 416 674 924 1271 780 825 900 282 286 343 212 285 162 224 132 240 181 310 334


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 6.2 4.3 4.3 4.2 3.7 3.2 3.4 – 3.4 3.0 3.1 6.1 6.0 5.9 6.7 6.6 6.9 7.1 7.4 7.7
Std Deviation (1e-4) 1.4 1.2 0.8 1.3 1.5 0.9 1.0 1.2 – 5.5 0.9 0.8 1.1 1.2 0.9 1.2 1.5 1.3 1.7 1.5 1.7
Intensity Change (Log2) – – – -0.01 -0.04 -0.21 -0.42 -0.33 – -0.35 -0.5 -0.5 0.5 0.48 0.45 0.64 0.61 0.68 0.73 0.77 0.84

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 2.6 3.8 2.3 2.6 2.6 – 2.6 1.8 2.4 1.7 1.7 0 2.7 2.7 0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 – 0 0 0 -8.6 -9.1 -8.9 -7.3 -7.0 -7.1
Nucleus -2.6 -3.3 -5.1 -6.6 -7.1 – -7.6 -7.3 -8.1 -0.6 -0.1 0.5 -0.8 -1.6 -1.7
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 1.7 0 0 0 0 0
Vacuole 0 0 0 0 0 – 0 0 0 0 0 0 0 2.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0264 0 0.0124 0.0108 0.0158 0.0002 0.0071 0 0.0042 0 0 0.0038 0.0565 0 0.0002 0 0.0035 0.0003
Bud 0.0002 0.0002 0.0002 0.0001 0.0001 0 0.0001 0 0.0001 0 0 0 0.001 0.0001 0.0005 0 0.0009 0.0001
Bud Neck 0.0011 0.0002 0.0005 0.0002 0.0004 0.0008 0.0008 0.0003 0.0007 0.0001 0.0012 0.0012 0.0011 0.0002 0.0004 0.0001 0.0081 0.0043
Bud Periphery 0.0004 0.0002 0.0002 0.0002 0.0002 0 0.0001 0 0.0002 0 0 0.0001 0.0009 0.0001 0.0014 0 0.0006 0.0002
Bud Site 0.0019 0.0003 0.0026 0.0002 0.0001 0.0001 0.0004 0.0001 0.0007 0 0.0001 0 0.0067 0.0003 0.0003 0.0001 0.0069 0.0007
Cell Periphery 0.0001 0 0.0001 0.0001 0 0 0 0 0.0002 0 0 0 0.0004 0 0.0002 0 0.0002 0.0001
Cytoplasm 0.0033 0.0009 0.0008 0.0002 0.0012 0.0004 0.0008 0.0003 0.0004 0.0007 0.0005 0.0009 0.1174 0.0001 0.0014 0.0002 0.0276 0.0271
Cytoplasmic Foci 0.0141 0 0.0021 0.0037 0.0008 0.0002 0.001 0 0.0001 0 0 0.0001 0.0315 0 0 0 0.1297 0.0003
Eisosomes 0.0002 0 0.0001 0 0 0 0.0001 0 0.0005 0 0 0 0.0003 0 0 0 0.0003 0
Endoplasmic Reticulum 0.0014 0.0001 0.0004 0.0002 0.0025 0.0002 0.0002 0 0.0003 0 0 0.0001 0.0186 0 0.0003 0 0.0017 0.0004
Endosome 0.0136 0.0006 0.0019 0.004 0.0093 0.0008 0.0013 0 0.0009 0 0.0001 0.0002 0.0242 0 0.0001 0 0.1413 0.0007
Golgi 0.0054 0 0.0016 0.003 0.0027 0 0.0009 0 0.0004 0 0 0.0002 0.0319 0 0 0 0.0343 0
Lipid Particles 0.0119 0 0.0007 0.0211 0.0005 0.0001 0.0018 0 0.0005 0 0 0.0001 0.0156 0 0 0 0.0043 0.0001
Mitochondria 0.0021 0.0004 0.0009 0.0034 0.0013 0.0003 0.0003 0.0001 0.0006 0.0001 0.0002 0.0001 0.0112 0.0004 0.0017 0.0005 0.0047 0.0004
None 0.0038 0.0001 0.0003 0.0001 0.0005 0.0002 0.0025 0.0003 0.0064 0.0012 0.0005 0.0028 0.0127 0 0.0009 0.0001 0.0607 0.0109
Nuclear Periphery 0.0111 0.0048 0.0045 0.0012 0.0067 0.0036 0.0073 0.0012 0.006 0.0018 0.0032 0.0019 0.0123 0.0005 0.0057 0.0012 0.0077 0.0052
Nucleolus 0.0239 0.0167 0.0156 0.0141 0.0285 0.0422 0.0152 0.0156 0.0088 0.011 0.0361 0.0452 0.013 0.0164 0.0171 0.0095 0.0671 0.0717
Nucleus 0.8505 0.9689 0.936 0.918 0.9262 0.9369 0.9518 0.9548 0.9602 0.9681 0.94 0.9315 0.6126 0.9812 0.9657 0.9878 0.3555 0.859
Peroxisomes 0.0154 0 0.0035 0.0149 0.0003 0.0001 0.0014 0 0.0001 0 0 0 0.0226 0 0 0 0.0047 0
Punctate Nuclear 0.0108 0.004 0.0153 0.0035 0.0022 0.0135 0.0066 0.0272 0.0088 0.0169 0.0178 0.0117 0.0039 0.0003 0.0015 0.0004 0.1348 0.0176
Vacuole 0.0016 0.0021 0.0002 0.0007 0.0002 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0001 0.0047 0.0001 0.0015 0.0001 0.0041 0.0006
Vacuole Periphery 0.0008 0.0005 0.0002 0.0004 0.0004 0.0001 0.0001 0 0.0001 0 0 0 0.0011 0.0001 0.0011 0 0.0013 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.1353 13.2723 7.6103 11.2773 13.5624 8.0939 9.6072 13.1743 12.0346 14.8181
Translational Efficiency 0.7417 0.5782 0.7215 0.5635 0.5457 1.0571 1.0721 0.4903 0.5418 0.5515

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2011 1673 2540 1152 2016 891 92 1663 4027 2564 2632 2815

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 744.39 840.13 920.27 983.29 755.13 805.97 1065.76 995.99 749.77 828.26 925.36 990.79
Standard Deviation 93.43 123.63 134.40 151.71 110.01 113.02 128.47 138.57 102.21 121.15 136.83 144.23
Intensity Change Log 2 — 0.174554 0.305999 0.401558 — 0.094001 0.497086 0.399406 — 0.134551 0.405387 0.400475

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000131 0.000537 0.000622 0.001651 0.000252 0.000569 0.001615 0.001081 0.000192 0.000548 0.000657 0.001314
Bud Neck 0.002876 0.006441 0.027981 0.029917 0.004579 0.007674 0.009424 0.025069 0.003728 0.006870 0.027333 0.027053
Bud Site 0.000404 0.000924 0.001756 0.011860 0.000874 0.001735 0.001242 0.006073 0.000639 0.001206 0.001738 0.008441
Cell Periphery 0.000054 0.000082 0.000072 0.000360 0.000116 0.000088 0.000048 0.000123 0.000085 0.000084 0.000072 0.000220
Cytoplasm 0.005900 0.003953 0.002321 0.012971 0.013117 0.007116 0.000374 0.010452 0.009513 0.005052 0.002253 0.011483
Cytoplasmic Foci 0.001167 0.000864 0.000016 0.004453 0.000900 0.002442 0.000037 0.002906 0.001033 0.001412 0.000017 0.003539
Eisosomes 0.000013 0.000023 0.000029 0.000046 0.000016 0.000030 0.000051 0.000031 0.000015 0.000026 0.000030 0.000037
Endoplasmic Reticulum 0.001478 0.003903 0.003200 0.007446 0.002450 0.004053 0.006928 0.005865 0.001965 0.003955 0.003330 0.006512
Endosome 0.000233 0.000690 0.000185 0.006343 0.000312 0.000896 0.000195 0.003236 0.000272 0.000762 0.000185 0.004507
Golgi 0.000227 0.000431 0.000086 0.005167 0.000283 0.001757 0.000107 0.004079 0.000255 0.000891 0.000086 0.004524
Lipid Particles 0.000425 0.000870 0.000058 0.001154 0.000437 0.001030 0.000177 0.001184 0.000431 0.000926 0.000062 0.001172
Mitochondria 0.001047 0.003521 0.001429 0.008893 0.001257 0.004411 0.001369 0.004504 0.001152 0.003830 0.001427 0.006300
Mitotic Spindle 0.002073 0.002942 0.003309 0.037055 0.000474 0.010902 0.000381 0.017321 0.001273 0.005708 0.003207 0.025397
None 0.008800 0.005771 0.002736 0.006354 0.012409 0.005355 0.001458 0.005597 0.010606 0.005627 0.002691 0.005907
Nuclear Periphery 0.000490 0.001071 0.000785 0.002729 0.000599 0.001475 0.000275 0.003039 0.000545 0.001211 0.000768 0.002912
Nuclear Periphery Foci 0.000469 0.000468 0.000136 0.001042 0.000624 0.000752 0.000127 0.001167 0.000546 0.000567 0.000136 0.001116
Nucleolus 0.030768 0.035375 0.018023 0.014774 0.027737 0.032016 0.020841 0.011984 0.029251 0.034208 0.018122 0.013126
Nucleus 0.942739 0.930498 0.936192 0.828986 0.932708 0.912979 0.952986 0.888544 0.937717 0.924410 0.936779 0.864171
Peroxisomes 0.000340 0.000656 0.000153 0.000641 0.000290 0.002815 0.000667 0.000499 0.000315 0.001406 0.000171 0.000557
Vacuole 0.000245 0.000610 0.000591 0.014901 0.000410 0.001484 0.001546 0.005567 0.000327 0.000914 0.000624 0.009387
Vacuole Periphery 0.000121 0.000370 0.000319 0.003257 0.000156 0.000419 0.000149 0.001681 0.000139 0.000387 0.000313 0.002326

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.27 -24.45 -16.85 -10.64 -10.76 -3.87 -9.04 -10.28 -5.84 3.93 -5.89 -16.50 -19.08 -11.31 -10.58
Bud Neck -6.14 -27.24 -18.21 -15.42 -1.24 -3.58 -4.63 -17.37 -12.48 -5.98 -6.38 -26.67 -25.26 -20.44 0.25
Bud Site -2.68 -7.17 -8.06 -7.54 -6.56 -1.95 -2.76 -6.04 -3.91 -3.28 -2.60 -5.70 -10.15 -8.88 -7.77
Cell Periphery -2.33 -2.05 -2.77 -2.27 -2.50 1.41 2.36 0.29 -1.44 -2.59 -0.11 1.66 -2.77 -2.70 -3.37
Cytoplasm 1.81 4.28 -2.83 -4.02 -5.54 2.80 9.45 1.68 -1.29 -7.61 4.10 8.65 -0.63 -4.28 -8.00
Cytoplasmic Foci 0.88 3.22 -0.77 -1.53 -3.15 -2.54 4.61 -1.32 1.32 -3.44 -1.11 4.96 -1.35 -0.45 -4.72
Eisosomes -7.43 -16.36 -11.74 -8.39 -6.40 -6.65 -7.99 -12.76 -1.68 4.27 -9.53 -17.45 -17.06 -8.77 -6.30
Endoplasmic Reticulum -7.67 -13.90 -16.13 -9.43 -11.66 -5.40 -6.92 -13.47 -5.27 1.34 -8.66 -12.13 -21.41 -10.60 -14.40
Endosome -2.19 0.70 -4.55 -3.68 -4.61 -2.64 -0.89 -3.95 -2.26 -3.48 -3.18 1.84 -6.03 -4.33 -6.20
Golgi -1.07 1.12 -2.80 -2.51 -3.04 -1.57 0.64 -2.38 -0.34 -2.66 -1.77 1.36 -3.52 -2.07 -3.94
Lipid Particles -1.92 4.48 -1.60 0.34 -3.79 -3.38 1.25 -1.26 1.10 -1.95 -3.18 5.44 -1.88 0.80 -4.30
Mitochondria -3.14 -2.63 -4.85 -1.90 -4.17 -3.11 -1.00 -3.79 0.66 -4.12 -4.21 -2.09 -6.32 -1.02 -5.64
Mitotic Spindle -0.98 -2.55 -7.95 -7.61 -6.98 -3.76 -1.34 -7.44 -1.75 -2.77 -3.90 -3.73 -10.75 -7.57 -8.04
None 2.53 6.31 3.38 0.58 -4.53 4.81 9.85 6.42 0.42 -6.02 5.32 10.72 7.01 0.80 -5.89
Nuclear Periphery -2.94 -2.19 -6.68 -4.61 -5.09 -4.93 -0.34 -3.69 -1.89 -3.40 -4.78 -1.95 -6.18 -4.01 -4.76
Nuclear Periphery Foci 0.29 2.50 -2.29 -2.87 -4.58 -0.61 -0.47 -1.31 -0.46 0.17 -0.00 3.80 -2.57 -2.72 -6.33
Nucleolus -1.99 4.32 7.65 9.38 4.24 -1.57 2.15 8.88 7.55 2.10 -2.88 4.48 11.90 12.95 6.48
Nucleus 2.88 5.24 13.40 11.54 11.16 3.51 -0.18 7.96 2.82 4.36 4.09 4.58 15.15 10.80 11.86
Peroxisomes -2.95 2.20 -1.52 1.88 -5.10 -2.57 -3.25 -1.34 2.44 2.10 -3.20 2.44 -1.87 2.83 -4.87
Vacuole -3.22 -5.36 -8.54 -8.33 -8.29 -3.71 -1.86 -8.11 -5.91 -0.86 -4.68 -4.60 -11.52 -10.63 -10.85
Vacuole Periphery -2.02 -1.10 -2.84 -2.25 -2.40 -2.83 -1.44 -2.60 -1.67 -2.47 -2.91 -1.00 -3.86 -2.80 -2.99
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description U1 snRNP protein involved in splicing; required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Prp42

Prp42


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Prp42-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available