Standard name
Human Ortholog
Description Subunit of a Golgi mannosyltransferase complex; complex mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family; other members of the complex are Anp1p, Mnn9p, Mnn11p, and Hoc1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.05 0 0.05 0.06 0 0.06 0.07 0.06 0.08 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.07 0.11 0.15 0.08 0.07 0.09 0.05 0.05 0.05 0 0 0 0.06 0.09 0.07 0 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.15 0.1 0.2 0.17 0.17 0 0 0 0 0 0 0 0.25 0.42 0.46 0.39 0.54 0.43 0.21 0.23 0.29 0.25 0.24 0.18
Golgi 0.15 0.17 0 0 0 0 0 0 0 0 0 0 0.5 0.21 0.12 0.2 0.18 0.22 0.56 0.45 0.34 0.46 0.45 0.55
Mitochondria 0.81 0.69 0.69 0.66 0.74 0.88 0.84 0.85 0.9 0.87 0.92 0.91 0.33 0.32 0.21 0.19 0.1 0.1 0.09 0.18 0.16 0.13 0.12 0.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.11 0.13 0.12 0 0.05 0.09 0 0 0.05 0.07 0.05 0.19 0.23 0.07 0.15 0.1 0.09 0.06 0.11 0.08 0.1 0.07
SpindlePole 0 0 0.07 0.1 0.09 0 0.05 0.05 0.06 0.1 0.05 0.05 0.05 0.1 0.11 0.27 0.23 0.2 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.08 0.06 0.06 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 9 10 3 0 2 4 0 0 0 2 2 5 27 7 1 10 6 15 7 14 8 6 8 8
Bud 9 5 22 13 24 28 26 37 35 35 42 59 4 7 3 14 10 10 0 0 0 1 0 1
Bud Neck 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0
Bud Site 0 0 0 0 1 4 4 2 7 4 5 14 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 2 0 0 2 3 1 0 0 1 3 3 2 3 2 3 1 0 0 0 0 0 0
Cytoplasm 5 27 49 48 38 35 52 34 24 28 23 22 7 24 34 27 16 22 0 5 7 1 4 4
Endoplasmic Reticulum 15 22 8 3 3 9 5 1 4 2 3 6 13 4 8 12 6 16 1 0 4 2 2 1
Endosome 58 40 87 56 81 9 17 24 3 13 3 2 76 175 179 146 196 163 92 112 148 108 64 62
Golgi 56 65 4 3 2 1 0 0 1 1 0 2 155 87 46 74 65 84 247 222 176 197 121 186
Mitochondria 304 266 307 212 353 430 488 529 464 489 480 546 101 134 81 70 37 38 40 90 81 56 31 32
Nucleus 1 0 0 1 1 3 8 4 1 5 0 2 0 1 1 3 0 1 0 0 0 1 0 0
Nuclear Periphery 3 2 0 0 1 3 6 1 1 5 5 6 0 0 2 1 4 3 0 1 1 1 1 0
Nucleolus 4 1 0 1 2 7 12 10 13 13 6 10 0 2 3 10 4 7 0 0 0 0 0 0
Peroxisomes 10 16 48 42 56 16 32 53 20 25 24 40 16 80 89 26 56 40 39 31 57 33 27 25
SpindlePole 9 9 32 32 43 18 28 34 29 56 24 33 17 40 43 103 82 78 2 2 5 0 1 1
Vac/Vac Membrane 21 17 10 5 21 10 16 15 10 6 15 5 10 25 30 24 21 22 7 10 19 14 6 10
Unique Cell Count 376 384 443 320 477 487 583 622 514 559 524 601 310 418 385 376 364 383 445 498 517 429 270 340
Labelled Cell Count 505 481 573 416 628 580 697 745 612 684 633 755 429 588 523 522 507 500 445 498 517 429 270 340


Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 6.0 4.7 5.0 4.8 4.6 4.4 4.5 4.3 4.1 4.2 4.4 7.7 7.3 7.5 7.3 7.0 7.2 7.8 8.1 8.2
Std Deviation (1e-4) 0.8 1.2 0.9 1.4 1.1 1.3 1.6 1.3 1.0 1.0 1.1 1.1 1.0 1.1 1.3 1.2 1.2 1.1 1.2 2.1 1.8
Intensity Change (Log2) – – – 0.09 0.03 -0.03 -0.08 -0.05 -0.12 -0.19 -0.14 -0.08 0.72 0.65 0.69 0.65 0.59 0.63 0.74 0.8 0.81

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 5.5 0 0 2.3 0 3.2
Bud -0.6 0 0 0 0 0 0 0 0 -2.7 -2.7 -3.5 -0.9 -1.6 -1.7
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.6 -1.6 -2.1 -1.1 -3.4 -3.7 -3.6 -3.9 -4.7 -4.5 -2.8 -1.1 -1.9 -3.5 -2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 2.0 -1.1 0.3 1.3 -0.2 2.0
Endosome -0.7 0 0 0 0 0 0 0 0 1.6 7.1 8.3 6.1 10.1 7.2
Golgi 0 0 0 0 0 0 0 0 0 16.2 9.5 6.7 9.1 8.6 9.8
Mitochondria -0.9 0 0 0 0 0 0 0 0 -10.0 -10.9 -13.9 -14.5 -16.9 -17.3
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 1.0 0 0 0 0 0 0 0 0 -2.7 3.4 4.7 -2.0 1.9 -0.2
SpindlePole 1.4 0 0 0 0 0 0 0 0 -1.0 1.2 2.0 7.8 6.2 5.5
Vacuole -0.7 1.8 -0.2 0.5 0.2 -0.3 -1.5 0.6 -1.9 0.8 2.8 3.7 2.9 2.6 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5416 4.0813 3.8781 3.2545 3.4453 3.9396 5.943 7.3177 6.468 6.6828 6.2006 6.8447 3.5431 4.6555 3.8698 4.9209 3.7205 4.4373
Actin 0.0242 0.0167 0.016 0.0054 0.0044 0.0079 0.0301 0.024 0.014 0.0023 0.0037 0.0238 0.0283 0.0042 0.0103 0.0011 0.0042 0.005
Bud 0.0005 0.0013 0.0091 0.0004 0.0001 0.0038 0.0001 0.0001 0.0002 0.0001 0 0.0001 0.0001 0 0.0001 0 0.0001 0
Bud Neck 0.0009 0.0004 0.0004 0.0003 0.0001 0.0006 0.0009 0.0002 0.0005 0.0002 0.0001 0.0002 0.0004 0.0001 0.0001 0.0001 0.0002 0.0003
Bud Periphery 0.0006 0.0005 0.0029 0.0003 0.0002 0.0017 0.0001 0.0001 0.0002 0.0001 0 0.0001 0.0001 0 0.0001 0 0.0001 0
Bud Site 0.0013 0.0067 0.0043 0.0009 0.0002 0.0009 0.0004 0.0003 0.0028 0.0002 0 0.0001 0.0004 0.0001 0.0003 0 0.0001 0.0001
Cell Periphery 0.0003 0.0001 0.0003 0.0001 0.0001 0.0007 0.0001 0 0.0002 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0051 0.0018 0.0028 0.002 0.0008 0.0091 0.0007 0.0005 0.0006 0.0003 0.0002 0.0005 0.0018 0.0005 0.0004 0.0004 0.0006 0.0004
Cytoplasmic Foci 0.1118 0.157 0.1017 0.1522 0.0911 0.1026 0.0976 0.1181 0.0797 0.0832 0.108 0.0754 0.1034 0.0978 0.0872 0.1144 0.0913 0.0737
Eisosomes 0.0004 0 0.0001 0 0.0001 0.0001 0.0003 0 0.0004 0 0 0.0001 0.0002 0 0.0001 0 0 0
Endoplasmic Reticulum 0.005 0.0002 0.0004 0.0011 0.0006 0.0007 0.0003 0.0001 0.0002 0.0001 0.0001 0.0002 0.0004 0.0002 0.0003 0.0001 0.0003 0.0002
Endosome 0.1858 0.175 0.1714 0.167 0.1968 0.1296 0.1235 0.0841 0.1105 0.1134 0.0762 0.0708 0.1339 0.1566 0.1378 0.1308 0.1573 0.1163
Golgi 0.4299 0.5498 0.5598 0.5753 0.6064 0.5995 0.5765 0.6876 0.6989 0.6209 0.6303 0.6878 0.529 0.682 0.6721 0.6127 0.5967 0.7069
Lipid Particles 0.0528 0.0096 0.0214 0.0281 0.0091 0.0314 0.052 0.0064 0.0127 0.0465 0.0499 0.0346 0.0662 0.0257 0.0199 0.0769 0.046 0.0275
Mitochondria 0.0562 0.0219 0.0415 0.0475 0.0621 0.0254 0.0224 0.0256 0.0314 0.0266 0.0027 0.0152 0.0331 0.0113 0.0257 0.0428 0.0208 0.0164
None 0.0116 0.0003 0.0005 0.0004 0.0002 0.0016 0.0013 0 0.0001 0 0 0.0004 0.0113 0 0.0001 0 0 0
Nuclear Periphery 0.0029 0.0005 0.0007 0.0004 0.0005 0.0025 0.0002 0 0 0 0 0.0001 0.0005 0.0001 0.0001 0.0001 0.0001 0.0001
Nucleolus 0.0066 0.0002 0.0001 0.0009 0 0.0008 0.0001 0 0 0 0 0 0.0005 0 0 0 0 0
Nucleus 0.0024 0.0001 0.0002 0.0002 0.0001 0.0005 0.0001 0 0 0 0 0 0.0007 0 0 0 0 0
Peroxisomes 0.0936 0.0545 0.061 0.0135 0.0141 0.0766 0.0912 0.0523 0.0465 0.1051 0.1282 0.0897 0.0854 0.0191 0.0427 0.0191 0.0793 0.0511
Punctate Nuclear 0.0034 0.0013 0.0002 0.0011 0.0001 0.0006 0.0006 0.0001 0.0001 0.0002 0.0001 0.0001 0.0023 0.0001 0.0001 0.0001 0.0001 0.0001
Vacuole 0.0024 0.0011 0.0029 0.0012 0.0041 0.002 0.0007 0.0001 0.0004 0.0003 0.0001 0.0002 0.0006 0.001 0.0008 0.0003 0.0006 0.0006
Vacuole Periphery 0.0023 0.0009 0.0025 0.0016 0.0087 0.0015 0.001 0.0003 0.0007 0.0006 0.0003 0.0006 0.0011 0.0011 0.0015 0.0008 0.0022 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 70.9465 78.4428 66.258 54.0105 61.1218 56.9124 76.7821 65.2056 62.2769 75.09
Translational Efficiency 1.0007 0.9141 0.776 0.9589 0.8844 0.8679 0.8563 0.7219 0.6569 0.661

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1665 1236 1447 1036 1747 2131 1127 1051 3412 3367 2574 2087

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 671.34 856.52 915.71 885.36 773.68 815.70 917.19 860.30 723.74 830.68 916.36 872.74
Standard Deviation 81.83 124.05 114.28 173.18 95.64 316.69 106.88 168.76 102.80 263.65 111.10 171.43
Intensity Change Log 2 — 0.351443 0.447847 0.399221 — 0.076302 0.245484 0.153103 — 0.210675 0.343039 0.272683

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000544 0.003156 0.004448 0.022274 0.003367 0.003381 0.004913 0.004703 0.001990 0.003299 0.004651 0.013425
Bud Neck 0.001767 0.000184 0.000468 0.003503 0.000067 0.000264 0.000098 0.003014 0.000897 0.000235 0.000306 0.003257
Bud Site 0.000532 0.001804 0.004646 0.040535 0.000202 0.000834 0.001201 0.018258 0.000363 0.001190 0.003138 0.029316
Cell Periphery 0.000046 0.000038 0.000043 0.000174 0.000026 0.000048 0.000025 0.000255 0.000036 0.000044 0.000035 0.000215
Cytoplasm 0.003257 0.002018 0.001966 0.026340 0.000270 0.001350 0.001203 0.014188 0.001728 0.001595 0.001632 0.020220
Cytoplasmic Foci 0.203382 0.284370 0.387610 0.273560 0.214942 0.211625 0.333994 0.261023 0.209301 0.238329 0.364135 0.267246
Eisosomes 0.000105 0.000040 0.000033 0.000087 0.000066 0.000052 0.000032 0.000066 0.000085 0.000048 0.000032 0.000076
Endoplasmic Reticulum 0.000071 0.000304 0.000919 0.000524 0.000055 0.000112 0.000379 0.001052 0.000062 0.000183 0.000683 0.000790
Endosome 0.134197 0.153372 0.145533 0.213460 0.225546 0.232757 0.197330 0.318318 0.180969 0.203616 0.168212 0.266266
Golgi 0.541142 0.502773 0.368078 0.253259 0.506961 0.498638 0.428472 0.216931 0.523641 0.500156 0.394521 0.234964
Lipid Particles 0.039690 0.012943 0.007509 0.005683 0.013142 0.011547 0.006280 0.016128 0.026097 0.012059 0.006971 0.010943
Mitochondria 0.037110 0.014876 0.004525 0.018593 0.017227 0.021477 0.002789 0.020018 0.026930 0.019054 0.003765 0.019311
Mitotic Spindle 0.003720 0.004133 0.050679 0.049955 0.000832 0.001149 0.006955 0.052239 0.002241 0.002245 0.031535 0.051105
None 0.000678 0.000091 0.000022 0.001300 0.000012 0.000394 0.000008 0.004351 0.000337 0.000283 0.000016 0.002837
Nuclear Periphery 0.000017 0.000031 0.000177 0.000233 0.000008 0.000011 0.000039 0.000189 0.000012 0.000019 0.000117 0.000211
Nuclear Periphery Foci 0.000144 0.000429 0.002415 0.001270 0.000040 0.000046 0.000378 0.001803 0.000091 0.000187 0.001523 0.001539
Nucleolus 0.000265 0.000050 0.000020 0.000119 0.000034 0.000012 0.000003 0.000485 0.000147 0.000026 0.000013 0.000303
Nucleus 0.000237 0.000315 0.000090 0.000286 0.000019 0.002726 0.000009 0.000525 0.000125 0.001841 0.000055 0.000407
Peroxisomes 0.030666 0.014568 0.007845 0.046081 0.015372 0.010385 0.008805 0.027160 0.022835 0.011920 0.008265 0.036552
Vacuole 0.001288 0.002311 0.009933 0.037203 0.000786 0.001435 0.004814 0.031508 0.001031 0.001757 0.007692 0.034335
Vacuole Periphery 0.001142 0.002192 0.003039 0.005561 0.001026 0.001758 0.002274 0.007785 0.001082 0.001917 0.002704 0.006681

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.92 -5.25 -7.53 -6.31 -5.95 -0.01 -1.36 -1.32 -1.27 0.14 -2.07 -3.97 -7.44 -6.33 -5.41
Bud Neck 4.58 3.60 -2.63 -5.17 -4.71 -1.23 -2.13 -7.12 -6.27 -7.04 3.37 3.28 -5.85 -7.69 -7.65
Bud Site -1.80 -6.46 -11.70 -11.08 -10.30 -1.56 -5.87 -7.98 -7.59 -7.51 -2.27 -7.53 -14.06 -13.45 -12.48
Cell Periphery 0.65 0.33 -3.97 -4.13 -4.10 -1.81 0.40 -3.13 -2.78 -3.15 -1.03 0.09 -4.47 -4.15 -4.48
Cytoplasm 1.24 1.70 -9.45 -9.74 -9.97 -2.84 -1.88 -8.60 -7.82 -7.64 0.19 -0.11 -12.50 -12.46 -12.47
Cytoplasmic Foci -13.41 -30.07 -8.88 2.34 15.50 0.68 -17.97 -6.57 -7.24 9.38 -7.62 -34.22 -10.92 -4.89 18.12
Eisosomes 8.12 9.67 1.11 -3.00 -3.52 2.38 6.47 -0.03 -1.60 -4.04 7.51 11.59 0.91 -3.22 -5.06
Endoplasmic Reticulum -2.71 -5.59 -7.97 -2.46 2.22 -1.11 -3.23 -2.98 -2.78 -1.95 -2.64 -6.45 -4.34 -3.53 -0.65
Endosome -3.51 -2.37 -10.10 -7.24 -9.04 -1.25 4.69 -10.24 -9.68 -13.64 -5.48 3.27 -13.73 -9.81 -16.65
Golgi 4.24 20.43 30.52 26.87 13.56 1.20 9.46 33.84 33.96 22.64 4.16 21.77 45.24 42.97 25.08
Lipid Particles 8.44 11.29 11.83 3.79 1.09 0.81 3.64 -1.35 -2.04 -4.41 7.58 11.32 7.96 0.44 -3.58
Mitochondria 7.05 12.04 5.79 -0.96 -5.48 -1.71 7.92 -0.78 0.67 -7.02 3.90 14.10 3.73 0.22 -8.70
Mitotic Spindle -0.35 -11.67 -10.65 -10.57 -0.78 -0.58 -3.91 -10.93 -10.90 -9.25 0.02 -12.24 -15.27 -15.33 -5.69
None 2.27 2.56 -0.76 -1.61 -1.71 -2.00 1.75 -3.25 -2.94 -3.25 0.32 2.57 -3.22 -3.29 -3.67
Nuclear Periphery -1.10 -3.56 -2.18 -2.03 -0.63 -1.94 -4.37 -5.48 -5.39 -4.50 -1.24 -4.12 -3.88 -3.76 -1.84
Nuclear Periphery Foci -1.67 -3.60 -2.99 -2.19 1.15 -0.66 -2.89 -5.49 -5.47 -4.28 -1.51 -4.02 -5.79 -5.33 -0.57
Nucleolus 2.61 2.99 1.37 -3.11 -4.43 0.71 1.00 -4.48 -4.89 -4.97 2.81 3.11 -2.61 -5.70 -5.96
Nucleus -0.27 1.93 -2.38 -0.69 -4.18 -3.00 0.22 -4.12 2.23 -4.16 -2.95 1.72 -4.77 2.13 -5.62
Peroxisomes 6.78 10.66 -4.03 -8.54 -10.74 2.91 3.13 -4.72 -7.40 -7.19 7.65 9.91 -5.99 -11.48 -12.98
Vacuole -2.14 -9.48 -12.97 -12.65 -10.31 -4.00 -5.52 -12.00 -11.79 -10.28 -3.40 -11.02 -17.62 -17.30 -14.31
Vacuole Periphery -3.05 -5.78 -6.65 -4.47 -3.26 -3.76 -4.91 -5.97 -5.27 -4.75 -4.73 -7.55 -8.46 -6.97 -5.65
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of a Golgi mannosyltransferase complex; complex mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family; other members of the complex are Anp1p, Mnn9p, Mnn11p, and Hoc1p
Localization
Cell Percentages Golgi (34%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mnn10

Mnn10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mnn10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available