| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 1 | 0 | 1 | – | 0 | – | 0 | – | – | – | – | 0 | – | – | – | – | – | – | 4 | 3 | 1 | 2 | 0 | 3 |
| Bud | 0 | 1 | 1 | – | 1 | – | 6 | – | – | – | – | 9 | – | – | – | – | – | – | 3 | 3 | 2 | 0 | 3 | 2 |
| Bud Neck | 3 | 1 | 3 | – | 3 | – | 7 | – | – | – | – | 1 | – | – | – | – | – | – | 2 | 1 | 0 | 0 | 0 | 0 |
| Bud Site | 0 | 0 | 0 | – | 0 | – | 1 | – | – | – | – | 5 | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | 3 | 2 | 3 | – | 0 | – | 1 | – | – | – | – | 2 | – | – | – | – | – | – | 1 | 0 | 2 | 1 | 0 | 0 |
| Cytoplasm | 355 | 273 | 157 | – | 211 | – | 306 | – | – | – | – | 271 | – | – | – | – | – | – | 319 | 237 | 157 | 94 | 110 | 93 |
| Endoplasmic Reticulum | 0 | 0 | 0 | – | 0 | – | 0 | – | – | – | – | 2 | – | – | – | – | – | – | 0 | 0 | 2 | 5 | 1 | 3 |
| Endosome | 1 | 1 | 0 | – | 0 | – | 1 | – | – | – | – | 1 | – | – | – | – | – | – | 6 | 3 | 5 | 4 | 1 | 3 |
| Golgi | 2 | 0 | 0 | – | 0 | – | 0 | – | – | – | – | 0 | – | – | – | – | – | – | 3 | 1 | 1 | 1 | 2 | 1 |
| Mitochondria | 7 | 3 | 12 | – | 32 | – | 132 | – | – | – | – | 200 | – | – | – | – | – | – | 27 | 12 | 34 | 8 | 2 | 4 |
| Nucleus | 1 | 0 | 0 | – | 1 | – | 0 | – | – | – | – | 1 | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 1 | 1 |
| Nuclear Periphery | 0 | 0 | 1 | – | 0 | – | 1 | – | – | – | – | 0 | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 1 | 0 |
| Nucleolus | 0 | 0 | 0 | – | 0 | – | 1 | – | – | – | – | 0 | – | – | – | – | – | – | 0 | 1 | 0 | 0 | 0 | 0 |
| Peroxisomes | 0 | 0 | 0 | – | 0 | – | 1 | – | – | – | – | 0 | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 2 | 0 | 1 | – | 0 | – | 7 | – | – | – | – | 12 | – | – | – | – | – | – | 6 | 5 | 4 | 0 | 1 | 2 |
| Vac/Vac Membrane | 1 | 0 | 1 | – | 0 | – | 0 | – | – | – | – | 2 | – | – | – | – | – | – | 7 | 8 | 4 | 7 | 4 | 7 |
| Unique Cell Count | 365 | 276 | 165 | 223 | 377 | 385 | 391 | 287 | 230 | 131 | 136 | 130 | ||||||||||||
| Labelled Cell Count | 376 | 281 | 180 | 248 | 464 | 506 | 391 | 287 | 230 | 131 | 136 | 130 | ||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 3.9 | 3.8 | 3.2 | – | 3.2 | – | 2.5 | – | – | – | – | 2.5 | – | – | – | 4.5 | 4.7 | 4.5 | – | – | – |
| Std Deviation (1e-4) | 0.8 | 1.0 | 1.2 | – | 1.5 | – | 1.3 | – | – | – | – | 1.3 | – | – | – | 1.0 | 1.3 | 1.3 | – | – | – |
| Intensity Change (Log2) | – | – | – | – | -0.03 | – | -0.37 | – | – | – | – | -0.39 | – | – | – | 0.48 | 0.54 | 0.49 | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | 0.0058 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0004 | 0.0139 | 0 | 0.0004 | 0.0001 | 0.004 | 0.005 | – | – | – | – | – | – |
| Bud | 0.0091 | 0.0067 | 0.0053 | 0.0149 | 0.0021 | 0.0065 | 0.0018 | 0.0001 | 0.0009 | 0.0001 | 0.0004 | 0.0006 | – | – | – | – | – | – |
| Bud Neck | 0.0028 | 0.0015 | 0.0012 | 0.0107 | 0.0001 | 0.0017 | 0.0015 | 0 | 0.0022 | 0.0001 | 0.0005 | 0.0003 | – | – | – | – | – | – |
| Bud Periphery | 0.0038 | 0.001 | 0.0011 | 0.0034 | 0.0018 | 0.0034 | 0.0071 | 0 | 0.0026 | 0.0001 | 0.001 | 0.0023 | – | – | – | – | – | – |
| Bud Site | 0.0071 | 0.018 | 0.0103 | 0.0197 | 0.0007 | 0.0014 | 0.0021 | 0.001 | 0.0053 | 0.0001 | 0.0002 | 0.0001 | – | – | – | – | – | – |
| Cell Periphery | 0.0006 | 0.0001 | 0.0002 | 0.0008 | 0.0001 | 0.0004 | 0.0009 | 0 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | – | – | – | – | – | – |
| Cytoplasm | 0.0142 | 0.0231 | 0.0091 | 0.0172 | 0.0077 | 0.0185 | 0.0182 | 0.011 | 0.0137 | 0.0145 | 0.0258 | 0.0228 | – | – | – | – | – | – |
| Cytoplasmic Foci | 0.0132 | 0.003 | 0.0024 | 0.0043 | 0.0018 | 0.0096 | 0.0067 | 0.0006 | 0.0015 | 0.0014 | 0.0013 | 0.0017 | – | – | – | – | – | – |
| Eisosomes | 0.0002 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.0002 | 0.0002 | 0.0001 | 0.0001 | – | – | – | – | – | – |
| Endoplasmic Reticulum | 0.0006 | 0.0003 | 0.0002 | 0.0004 | 0.0001 | 0.0003 | 0.0019 | 0.0001 | 0.0002 | 0.0002 | 0.004 | 0.0009 | – | – | – | – | – | – |
| Endosome | 0.0021 | 0.0004 | 0.0002 | 0.0001 | 0 | 0.0001 | 0.0016 | 0 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | – | – | – | – | – | – |
| Golgi | 0.0008 | 0.0001 | 0 | 0 | 0 | 0 | 0.0013 | 0 | 0.0001 | 0 | 0.0001 | 0.0003 | – | – | – | – | – | – |
| Lipid Particles | 0.0024 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0002 | 0.0015 | 0 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | – | – | – | – | – | – |
| Mitochondria | 0.002 | 0.0002 | 0.0003 | 0.0003 | 0.0002 | 0.0006 | 0.0009 | 0 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | – | – | – | – | – | – |
| None | 0.9227 | 0.9353 | 0.9653 | 0.9051 | 0.9823 | 0.9498 | 0.9317 | 0.9782 | 0.9697 | 0.982 | 0.9522 | 0.9615 | – | – | – | – | – | – |
| Nuclear Periphery | 0.0021 | 0.0002 | 0.0002 | 0.0009 | 0.0001 | 0.0002 | 0.0009 | 0.0001 | 0.0002 | 0.0001 | 0.0038 | 0.0008 | – | – | – | – | – | – |
| Nucleolus | 0.001 | 0.0007 | 0.0006 | 0.0016 | 0.0002 | 0.0009 | 0.001 | 0.0003 | 0.0002 | 0.0001 | 0.0001 | 0.0002 | – | – | – | – | – | – |
| Nucleus | 0.002 | 0.004 | 0.0015 | 0.0069 | 0.0006 | 0.0027 | 0.001 | 0.0016 | 0.0006 | 0.0002 | 0.0031 | 0.0006 | – | – | – | – | – | – |
| Peroxisomes | 0.0016 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0019 | 0 | 0.0002 | 0.0001 | 0.0001 | 0.0004 | – | – | – | – | – | – |
| Punctate Nuclear | 0.0036 | 0.0046 | 0.0014 | 0.0111 | 0.0016 | 0.0023 | 0.0026 | 0.0068 | 0.0013 | 0.0002 | 0.0005 | 0.0011 | – | – | – | – | – | – |
| Vacuole | 0.0019 | 0.0002 | 0.0003 | 0.0014 | 0.0001 | 0.0005 | 0.0009 | 0 | 0.0001 | 0.0001 | 0.0007 | 0.0002 | – | – | – | – | – | – |
| Vacuole Periphery | 0.0004 | 0 | 0.0001 | 0.0003 | 0 | 0.0001 | 0.0002 | 0 | 0 | 0 | 0.0003 | 0.0001 | – | – | – | – | – | – |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 338.246 | 410.9901 | 431.3181 | 647.5978 | 391.7152 | 229.7487 | 553.5741 | 671.1231 | 542.7358 | 543.3263 |
| Translational Efficiency | 2.5776 | 2.8264 | 3.2378 | 1.7609 | 2.7107 | 6.8497 | 3.2419 | 2.4498 | 3.6176 | 2.7514 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✔ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 155 | 1880 | 1791 | 1279 | 1708 | 1886 | 130 | 1769 | 1863 | 3766 | 1921 | 3048 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 645.66 | 700.37 | 741.59 | 796.44 | 644.91 | 664.84 | 846.66 | 800.59 | 644.97 | 682.58 | 748.70 | 798.85 |
| Standard Deviation | 63.28 | 82.21 | 83.62 | 116.59 | 70.47 | 80.14 | 97.45 | 141.61 | 69.90 | 83.10 | 88.65 | 131.70 |
| Intensity Change Log 2 | — | 0.117343 | 0.199847 | 0.302791 | — | 0.043909 | 0.392685 | 0.311966 | — | 0.081114 | 0.299430 | 0.307383 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000057 | 0.000500 | 0.000075 | 0.000681 | 0.000079 | 0.000500 | 0.000266 | 0.000461 | 0.000077 | 0.000500 | 0.000087 | 0.000553 |
| Bud Neck | 0.018879 | 0.042848 | 0.002110 | 0.007465 | 0.013272 | 0.053195 | 0.000705 | 0.010303 | 0.013739 | 0.048030 | 0.002015 | 0.009112 |
| Bud Site | 0.002264 | 0.014111 | 0.004465 | 0.029426 | 0.003465 | 0.014353 | 0.001966 | 0.030771 | 0.003365 | 0.014233 | 0.004296 | 0.030207 |
| Cell Periphery | 0.000164 | 0.000137 | 0.000118 | 0.000298 | 0.000093 | 0.000179 | 0.000149 | 0.000243 | 0.000099 | 0.000158 | 0.000120 | 0.000266 |
| Cytoplasm | 0.371676* | 0.409374* | 0.459044* | 0.444052* | 0.513763* | 0.367645* | 0.198892* | 0.544903* | 0.501942* | 0.388476* | 0.441439* | 0.502584* |
| Cytoplasmic Foci | 0.331707* | 0.252828* | 0.017144 | 0.022491 | 0.227500* | 0.298944* | 0.026773 | 0.029090 | 0.236170* | 0.275923* | 0.017796 | 0.026321 |
| Eisosomes | 0.000214 | 0.000144 | 0.000030 | 0.000050 | 0.000132 | 0.000249 | 0.000083 | 0.000044 | 0.000139 | 0.000196 | 0.000033 | 0.000047 |
| Endoplasmic Reticulum | 0.000384 | 0.000456 | 0.000692 | 0.003142 | 0.000448 | 0.000554 | 0.002532 | 0.000691 | 0.000443 | 0.000505 | 0.000817 | 0.001719 |
| Endosome | 0.035638 | 0.018596 | 0.001504 | 0.008373 | 0.010462 | 0.023669 | 0.005790 | 0.008706 | 0.012556 | 0.021137 | 0.001794 | 0.008566 |
| Golgi | 0.001421 | 0.005883 | 0.000106 | 0.006987 | 0.002221 | 0.008807 | 0.004049 | 0.004395 | 0.002155 | 0.007348 | 0.000372 | 0.005483 |
| Lipid Particles | 0.018952 | 0.006089 | 0.000881 | 0.001517 | 0.007476 | 0.009880 | 0.004196 | 0.000972 | 0.008431 | 0.007988 | 0.001106 | 0.001201 |
| Mitochondria | 0.006688 | 0.015218 | 0.000368 | 0.008262 | 0.003722 | 0.023932 | 0.000350 | 0.003037 | 0.003969 | 0.019582 | 0.000367 | 0.005230 |
| Mitotic Spindle | 0.000053 | 0.007482 | 0.001471 | 0.032085 | 0.002565 | 0.008682 | 0.001722 | 0.038018 | 0.002356 | 0.008083 | 0.001488 | 0.035528 |
| None | 0.003922 | 0.002372 | 0.008346 | 0.006731 | 0.004412 | 0.002003 | 0.003064 | 0.005883 | 0.004371 | 0.002187 | 0.007989 | 0.006239 |
| Nuclear Periphery | 0.001117 | 0.000339 | 0.000770 | 0.001891 | 0.000399 | 0.000318 | 0.001470 | 0.000930 | 0.000459 | 0.000328 | 0.000817 | 0.001333 |
| Nuclear Periphery Foci | 0.000336 | 0.000211 | 0.000286 | 0.001867 | 0.000410 | 0.000220 | 0.000850 | 0.000521 | 0.000404 | 0.000215 | 0.000324 | 0.001085 |
| Nucleolus | 0.001653 | 0.001757 | 0.000644 | 0.000774 | 0.002323 | 0.001494 | 0.000832 | 0.000846 | 0.002267 | 0.001626 | 0.000656 | 0.000816 |
| Nucleus | 0.144640* | 0.138157* | 0.479804* | 0.296308* | 0.161796* | 0.105302 | 0.697334* | 0.234069* | 0.160369* | 0.121703 | 0.494525* | 0.260186* |
| Peroxisomes | 0.009189 | 0.016366 | 0.000322 | 0.001486 | 0.004766 | 0.024532 | 0.000577 | 0.001720 | 0.005134 | 0.020456 | 0.000339 | 0.001622 |
| Vacuole | 0.049145 | 0.065482 | 0.021608 | 0.120011 | 0.039788 | 0.053595 | 0.047980 | 0.080691 | 0.040567 | 0.059529 | 0.023393 | 0.097191 |
| Vacuole Periphery | 0.001902 | 0.001651 | 0.000211 | 0.006105 | 0.000906 | 0.001946 | 0.000422 | 0.003705 | 0.000989 | 0.001799 | 0.000226 | 0.004712 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -1.71 | -1.66 | -6.00 | 0.27 | -5.56 | -4.59 | -2.47 | -3.32 | 1.06 | -0.70 | -3.09 | -1.63 | -5.55 | 0.73 | -5.07 |
| Bud Neck | -4.39 | 3.21 | 2.36 | 15.81 | -5.43 | -14.20 | 10.95 | 3.28 | 16.23 | -8.08 | -17.03 | 10.44 | 4.86 | 22.36 | -8.47 |
| Bud Site | -8.48 | -2.16 | -6.05 | -0.64 | -4.89 | -9.71 | 1.82 | -8.47 | -3.28 | -8.83 | -12.26 | -1.19 | -10.12 | -3.05 | -8.74 |
| Cell Periphery | 1.36 | 3.25 | -0.31 | -1.24 | -2.10 | -5.43 | -3.36 | -1.85 | 0.14 | -0.54 | -4.52 | -2.79 | -2.72 | -0.57 | -1.95 |
| Cytoplasm | -1.74 | -3.25 | 0.68 | 5.04 | 8.03 | 16.34 | 19.80 | 3.52 | -11.83 | -17.54 | 14.99 | 8.83 | 9.04 | -5.78 | -0.76 |
| Cytoplasmic Foci | 4.21 | 17.45 | 17.47 | 44.07 | 0.38 | -9.59 | 29.79 | 38.96 | 49.66 | 0.23 | -6.31 | 43.70 | 43.11 | 65.71 | -2.47 |
| Eisosomes | 3.92 | 10.98 | 9.09 | 9.00 | -12.71 | -8.64 | 2.74 | 9.81 | 18.58 | 4.30 | -5.46 | 12.99 | 10.71 | 20.09 | -8.93 |
| Endoplasmic Reticulum | -0.84 | -5.34 | -10.37 | -10.29 | -8.80 | -0.97 | -6.66 | -8.73 | -4.86 | 5.49 | -0.93 | -8.84 | -12.47 | -11.46 | -6.75 |
| Endosome | 2.51 | 5.11 | 4.66 | 11.75 | -4.85 | -8.53 | 3.02 | 5.13 | 11.89 | -0.34 | -6.87 | 12.50 | 7.78 | 16.32 | -6.37 |
| Golgi | -5.95 | 3.99 | -1.18 | 3.21 | -2.91 | -6.76 | -0.04 | -0.33 | 6.03 | -0.07 | -7.37 | 4.04 | -0.47 | 6.62 | -4.28 |
| Lipid Particles | 3.51 | 5.00 | 4.82 | 8.30 | -5.90 | -2.93 | 3.57 | 11.04 | 15.74 | 3.98 | 0.59 | 11.68 | 11.61 | 17.18 | -0.89 |
| Mitochondria | -2.41 | 1.89 | 0.95 | 7.22 | -3.15 | -10.21 | 5.38 | 2.35 | 11.47 | -4.97 | -11.80 | 5.64 | 1.79 | 13.71 | -5.01 |
| Mitotic Spindle | -5.69 | -3.47 | -7.90 | -4.70 | -7.25 | -3.75 | -0.51 | -8.34 | -5.91 | -3.83 | -4.59 | 0.66 | -10.44 | -7.61 | -11.14 |
| None | 1.17 | -2.67 | -0.42 | -3.64 | 3.77 | 3.08 | 2.24 | -0.34 | -4.03 | -2.98 | 3.19 | -3.16 | -0.29 | -5.33 | 3.51 |
| Nuclear Periphery | 1.13 | 0.31 | -3.07 | -18.24 | -14.67 | 1.27 | -8.46 | -13.41 | -14.88 | 3.32 | 1.69 | -6.78 | -16.59 | -23.22 | -14.86 |
| Nuclear Periphery Foci | 1.66 | -0.29 | -6.88 | -7.75 | -7.06 | 2.93 | -3.72 | -1.04 | -4.60 | 3.36 | 3.29 | 0.15 | -5.73 | -8.93 | -6.60 |
| Nucleolus | -0.43 | 3.26 | 2.91 | 4.71 | -0.58 | 1.93 | 3.69 | 3.68 | 3.38 | -0.07 | 1.64 | 4.12 | 3.91 | 5.69 | -0.69 |
| Nucleus | 0.52 | -23.72 | -12.19 | -22.32 | 16.19 | 11.13 | -22.28 | -16.60 | -25.27 | 16.72 | 8.54 | -44.83 | -23.38 | -32.99 | 24.70 |
| Peroxisomes | -3.22 | 4.51 | 4.32 | 15.91 | -1.82 | -13.76 | 8.42 | 6.89 | 17.31 | -3.00 | -15.80 | 9.78 | 8.40 | 23.23 | -3.95 |
| Vacuole | -2.52 | 2.76 | -17.94 | -21.47 | -27.24 | -5.63 | -4.02 | -19.66 | -16.23 | -2.96 | -9.44 | 3.40 | -30.61 | -26.02 | -31.67 |
| Vacuole Periphery | 0.49 | 3.55 | -0.38 | -0.76 | -2.67 | -4.89 | 3.41 | -2.27 | -0.37 | -3.32 | -5.29 | 7.18 | -2.61 | -0.85 | -4.42 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential |
| Localization | |
| Cell Percentages | cytoplasm (24%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | cytoplasm-9 |
Pmp3
Pmp3
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Pmp3-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
