Standard name
Human Ortholog
Description Peroxisomal membrane protein (PMP); required for proper localization and stability of PMPs; anchors peroxisome retention factor Inp1p at the peroxisomal membrane; interacts with Pex19p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0.07 0.09 0 0 0 0 0 0 0 0 0 0
Bud 0.05 0.12 0.09 0.15 0.13 0.13 0.16 0.18 – 0.21 0.22 0.21 0.07 0.11 0.08 0.07 0.06 0.08 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0.08 0.14 0.08 0.1 0.07 0.1 0.06 0.05 – 0.1 0.1 0.07 0.05 0.06 0 0.1 0.09 0.06 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.06 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.07 0 0.1 0.05 0 0.05 – 0 0 0 0.05 0.05 0.06 0.06 0.09 0.06 0.09 0.08 0.07 0.09 0.05 0.06
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.3 0.53 0.19 0.22 0.17 0.28 0.21 0.2 – 0.36 0.38 0.28 0.13 0.11 0.08 0.11 0.07 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0.09 0.11 0.09 0 0 0 0 0 0
Peroxisomes 0.55 0.54 0.74 0.74 0.72 0.67 0.65 0.63 – 0.66 0.57 0.67 0.54 0.56 0.61 0.58 0.53 0.58 0.62 0.55 0.65 0.68 0.77 0.74
SpindlePole 0.37 0.16 0.39 0.34 0.43 0.37 0.42 0.36 – 0.3 0.32 0.34 0.46 0.48 0.41 0.27 0.31 0.25 0.15 0.15 0.2 0.14 0.09 0.1
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 13 7 7 3 2 10 36 – 13 16 15 45 67 32 7 3 7 0 12 6 10 21 25
Bud 4 39 42 56 77 85 147 167 – 177 161 200 44 83 61 13 20 18 3 15 5 14 20 15
Bud Neck 0 5 6 1 6 9 7 6 – 8 6 2 9 12 9 2 7 3 1 14 9 16 11 16
Bud Site 6 44 38 36 43 63 56 43 – 84 71 62 31 50 16 18 28 13 – – – – – –
Cell Periphery 0 0 0 0 0 1 0 1 – 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0
Cytoplasm 1 2 9 3 2 4 14 18 – 5 3 5 11 10 13 10 21 11 0 1 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 2 0 0 – 0 0 1 0 0 0 1 4 4 0 1 0 0 1 2
Endosome 3 8 31 12 58 32 34 42 – 6 9 31 34 40 47 11 31 13 9 26 33 56 46 69
Golgi 0 0 0 0 0 1 0 0 – 0 0 0 3 6 9 1 1 1 0 6 1 4 5 11
Mitochondria 22 168 90 84 100 182 194 178 – 300 277 264 83 85 62 21 23 15 4 9 3 6 14 15
Nucleus 0 1 0 1 7 5 6 4 – 4 5 4 5 8 6 6 11 1 0 0 0 0 0 0
Nuclear Periphery 0 2 1 0 0 0 1 0 – 4 1 2 2 1 0 11 7 8 0 0 0 0 1 0
Nucleolus 4 13 17 16 17 28 30 23 – 28 23 45 14 12 15 17 37 21 0 3 0 2 1 1
Peroxisomes 40 171 349 275 425 441 607 570 – 546 418 635 342 438 470 109 174 131 68 189 313 446 709 802
SpindlePole 27 52 186 129 253 244 394 324 – 246 232 321 294 374 319 51 101 56 16 52 97 94 80 107
Vac/Vac Membrane 0 0 0 0 1 0 1 3 – 2 0 1 2 4 1 0 4 3 0 0 1 0 1 4
Unique Cell Count 73 317 472 374 592 654 933 903 832 727 948 636 778 770 187 327 225 110 342 481 658 921 1080
Labelled Cell Count 108 518 776 620 992 1099 1501 1415 1423 1223 1588 919 1190 1060 279 473 305 110 342 481 658 921 1080


Peroxisomes

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 6.7 6.2 6.0 5.8 5.3 5.1 5.7 – 4.9 5.0 5.2 7.7 7.4 8.2 6.5 8.0 9.1 7.4 7.7 7.8
Std Deviation (1e-4) 1.6 1.3 1.3 1.2 1.2 1.4 1.3 1.3 – 1.2 1.2 1.2 1.2 1.1 1.2 2.0 2.5 2.8 1.4 1.6 1.6
Intensity Change (Log2) – – – -0.05 -0.1 -0.22 -0.27 -0.12 – -0.34 -0.3 -0.26 0.32 0.27 0.4 0.08 0.37 0.56 0.27 0.32 0.34


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.4 0 0 -0.7 2.5 – 0.1 0.9 0.1 4.4 5.2 2.6 0 0 0
Bud 2.7 2.1 2.1 3.6 4.7 – 5.7 6.0 5.8 -1.2 1.0 -0.6 -0.8 -1.4 -0.4
Bud Neck 0 -0.4 0.2 0 0 – -0.5 0 0 0.2 0.4 -0.2 0 1.0 0
Bud Site 0.8 -0.5 0.9 -1.5 -2.5 – 1.2 1.0 -1.0 -2.2 -1.1 -5.0 0.7 0.3 -1.1
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm -1.3 0 -2.0 -0.6 0.1 – -2.2 0 0 -0.2 -0.9 -0.3 2.4 3.3 2.2
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome -2.2 1.9 -1.2 -2.5 -1.5 – -6.1 -5.0 -2.9 -0.9 -1.1 -0.3 -0.3 1.5 -0.4
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 1.2 -0.9 3.4 0.8 0.3 – 6.4 7.0 3.6 -2.7 -4.0 -5.7 -2.4 -4.8 -4.3
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0.5 -0.7 0.6 -0.4 -1.1 – -0.2 -0.4 1.0 -1.4 -2.3 -1.8 2.9 4.3 3.1
Peroxisomes -0.1 -0.8 -2.4 -3.4 -4.0 – -3.1 -5.8 -2.7 -6.9 -6.3 -4.7 -3.9 -6.1 -4.2
SpindlePole -1.5 1.1 -0.7 1.0 -1.3 – -3.6 -2.7 -2.1 2.3 3.0 0.7 -2.9 -2.5 -3.8
Vacuole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.7721 3.5805 3.9144 3.3616 2.7077 4.0163 3.6199 4.4069 4.5463 4.3036 3.6685 4.7483 3.5395 4.0919 4.0602 3.9082 3.3531 4.0585
Actin 0.0202 0.021 0.0236 0.0006 0.0047 0.0074 0.0222 0.0194 0.0239 0.0015 0.0016 0.0223 0.0084 0.0501 0.0124 0.0059 0.0011 0.0029
Bud 0.0009 0.0049 0.0053 0 0.0001 0.0002 0.0002 0.0027 0.0026 0.0002 0.0016 0.0005 0.0001 0.0084 0.0003 0.0001 0.0001 0.0001
Bud Neck 0.0028 0.0016 0.0175 0.0007 0.0001 0.0019 0.0018 0.0154 0.02 0.014 0.0003 0.0015 0.0012 0.006 0.0011 0.0002 0.0003 0.0035
Bud Periphery 0.0009 0.0051 0.0054 0.0001 0.0001 0.0002 0.0003 0.0034 0.0032 0.0002 0.0021 0.0014 0.0001 0.0067 0.0004 0.0001 0.0001 0.0001
Bud Site 0.0278 0.0583 0.0142 0.0003 0.0004 0.0003 0.0014 0.0632 0.0221 0.0006 0.0082 0.0008 0.0012 0.0632 0.0022 0.0007 0.0002 0.0002
Cell Periphery 0.0131 0.0143 0.0002 0 0 0 0.0001 0.0005 0.0003 0.0001 0.0004 0.0001 0.0001 0.0006 0.0001 0 0 0
Cytoplasm 0.0062 0.0014 0.0001 0 0.0001 0.0168 0.0003 0.0002 0.0007 0.0001 0.0337 0.0001 0.0027 0.0015 0.0003 0.0002 0 0.0001
Cytoplasmic Foci 0.1416 0.1724 0.1248 0.2157 0.0977 0.0969 0.1474 0.162 0.1223 0.2131 0.1415 0.1224 0.1149 0.1597 0.1537 0.1784 0.1401 0.1668
Eisosomes 0.0001 0.0001 0.0001 0 0 0 0.0002 0.0001 0.0001 0 0 0.0001 0.0001 0.0001 0 0.0001 0 0
Endoplasmic Reticulum 0.001 0.0081 0 0 0 0 0.0004 0 0.0003 0 0.0012 0.0002 0.0007 0.0006 0.0001 0.0001 0 0.0001
Endosome 0.0103 0.005 0.0029 0.0009 0.0061 0.0018 0.0171 0.0043 0.0102 0.0037 0.0065 0.0045 0.0157 0.0072 0.0044 0.0051 0.0027 0.0064
Golgi 0.0117 0.01 0.0141 0.0053 0.0144 0.0076 0.0159 0.0094 0.0147 0.0096 0.0112 0.013 0.013 0.0145 0.0099 0.0106 0.0113 0.0113
Lipid Particles 0.1511 0.081 0.0994 0.0605 0.2666 0.141 0.1228 0.1155 0.0774 0.1916 0.1926 0.195 0.1557 0.064 0.1009 0.2142 0.074 0.1541
Mitochondria 0.0047 0.0145 0.0264 0.0036 0.0092 0.011 0.0165 0.0209 0.0234 0.0295 0.0449 0.016 0.0061 0.0122 0.0127 0.0116 0.0023 0.0125
None 0.0026 0.0003 0.0001 0 0.0001 0.017 0.0004 0.0002 0.0016 0 0.0012 0.0001 0.0055 0.0001 0.0001 0.0004 0 0.0001
Nuclear Periphery 0.0066 0.0007 0 0 0 0 0.0026 0.0001 0.0004 0 0.0002 0.0003 0.0012 0.0003 0.0003 0.0001 0 0.0005
Nucleolus 0.0017 0.0082 0.0011 0.0002 0.0001 0.0002 0.0003 0.006 0.0024 0.0007 0.0029 0.0028 0.0012 0.0029 0.0075 0.0002 0.0001 0.0005
Nucleus 0.0025 0.0013 0.0002 0 0 0 0.0002 0.0006 0.0004 0.0001 0.0005 0.0002 0.0005 0.0101 0.0019 0 0 0.0001
Peroxisomes 0.5728 0.5786 0.6618 0.7052 0.5988 0.6744 0.6428 0.5594 0.6611 0.5219 0.5312 0.6142 0.6522 0.5704 0.678 0.5694 0.7664 0.6204
Punctate Nuclear 0.0176 0.0122 0.0021 0.0069 0.0013 0.023 0.0061 0.0132 0.0102 0.0129 0.0159 0.0033 0.0187 0.0185 0.0115 0.0022 0.0011 0.0199
Vacuole 0.0034 0.0009 0.0004 0 0.0001 0.0001 0.0004 0.0031 0.002 0.0002 0.0017 0.0009 0.0004 0.0025 0.0018 0.0001 0 0.0002
Vacuole Periphery 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0006 0.0004 0.0007 0.0001 0.0005 0.0003 0.0004 0.0003 0.0003 0.0001 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.6426 13.3897 17.1116 18.9142 14.0256 14.97 19.1793 21.5746 21.7285 21.1026
Translational Efficiency 0.9063 1.0027 0.8013 0.7819 0.9466 1.0132 0.9008 0.7796 0.8042 0.7783

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
164 822 331 1346 1750 925 2583 1448 1914 1747 2914 2794

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 979.18 875.66 1113.18 1030.60 727.56 849.23 997.48 995.60 749.12 861.67 1010.62 1012.46
Standard Deviation 157.20 151.15 135.16 163.39 123.08 115.34 127.27 151.44 144.67 134.05 133.34 158.28
Intensity Change Log 2 — -0.161203 0.185041 0.073839 — 0.223089 0.455222 0.452500 — 0.015261 0.306451 0.247533

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.137016* 0.020710 0.046578 0.234884* 0.006451 0.009902 0.026320 0.179002* 0.017639 0.014988 0.028621 0.205923*
Bud Neck 0.004175 0.005743 0.011573 0.003255 0.008148 0.003749 0.003725 0.003455 0.007807 0.004687 0.004616 0.003359
Bud Site 0.016574 0.025652 0.061631 0.025269 0.018533 0.013874 0.023172 0.016686 0.018365 0.019416 0.027541 0.020821
Cell Periphery 0.000218 0.000282 0.000170 0.000179 0.000766 0.000127 0.000086 0.000154 0.000719 0.000200 0.000095 0.000166
Cytoplasm 0.003276 0.005869 0.007682 0.005862 0.008661 0.003705 0.009554 0.006394 0.008200 0.004723 0.009341 0.006138
Cytoplasmic Foci 0.069848 0.099304 0.143684 0.048736 0.123392 0.077552 0.072579 0.050805 0.118804 0.087786 0.080656 0.049808
Eisosomes 0.000345 0.000656 0.000464 0.001611 0.000562 0.000243 0.000276 0.001812 0.000543 0.000437 0.000297 0.001715
Endoplasmic Reticulum 0.000940 0.000452 0.000794 0.000260 0.000214 0.000141 0.000075 0.000175 0.000276 0.000288 0.000156 0.000216
Endosome 0.060100 0.025616 0.027158 0.018753 0.009646 0.032699 0.008544 0.013283 0.013969 0.029367 0.010659 0.015918
Golgi 0.065732 0.041338 0.020663 0.030159 0.030969 0.053352 0.016478 0.025137 0.033947 0.047699 0.016953 0.027557
Lipid Particles 0.022479 0.063881 0.022937 0.022998 0.028852 0.038516 0.018537 0.027950 0.028306 0.050450 0.019036 0.025565
Mitochondria 0.011945 0.013278 0.002607 0.013936 0.010887 0.018962 0.008977 0.013202 0.010977 0.016288 0.008253 0.013556
Mitotic Spindle 0.014549 0.013239 0.082759 0.014846 0.004469 0.013580 0.031563 0.008931 0.005332 0.013420 0.037379 0.011780
None 0.000045 0.000526 0.000062 0.000083 0.001654 0.000074 0.000042 0.000094 0.001516 0.000287 0.000044 0.000088
Nuclear Periphery 0.000088 0.000077 0.000191 0.000064 0.000022 0.000045 0.000070 0.000061 0.000027 0.000060 0.000083 0.000062
Nuclear Periphery Foci 0.000405 0.001263 0.005644 0.000182 0.001529 0.000458 0.000367 0.000590 0.001432 0.000837 0.000966 0.000393
Nucleolus 0.000036 0.000980 0.001030 0.000030 0.000534 0.000159 0.000108 0.000069 0.000491 0.000545 0.000213 0.000051
Nucleus 0.000084 0.000713 0.000947 0.000045 0.000639 0.000082 0.000037 0.000049 0.000592 0.000379 0.000140 0.000047
Peroxisomes 0.584388* 0.677957* 0.556974* 0.576063* 0.743155* 0.731403* 0.778800* 0.651029* 0.729551* 0.706256* 0.753603* 0.614915*
Vacuole 0.002426 0.002113 0.006236 0.001927 0.000559 0.000717 0.000565 0.001039 0.000719 0.001374 0.001209 0.001467
Vacuole Periphery 0.005332 0.000351 0.000215 0.000857 0.000359 0.000659 0.000126 0.000083 0.000785 0.000514 0.000136 0.000456

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 5.88 4.40 -4.60 -25.14* -18.27 -2.37 -11.37 -23.77* -23.08* -20.66* 1.11 -4.30 -32.44* -34.02* -31.25*
Bud Neck -0.99 -3.87 0.60 3.47 6.06 3.10 3.28 3.41 0.38 0.58 2.47 2.51 3.62 2.54 3.09
Bud Site -1.64 -5.26 -1.76 0.03 4.66 1.54 -1.88 0.67 -1.03 2.79 -0.37 -3.78 -1.09 -0.64 3.07
Cell Periphery -1.04 0.84 0.82 1.87 0.01 4.53 4.82 4.34 -1.52 -4.77 3.97 4.82 4.28 1.23 -5.23
Cytoplasm -2.64 -2.60 -2.98 -0.09 1.13 5.14 -0.62 2.00 -2.99 3.14 3.85 -0.99 2.16 -2.25 4.17
Cytoplasmic Foci -3.03 -5.48 2.43 8.69 8.62 7.51 9.20 13.07 5.73 5.88 5.68 7.27 14.22 10.28 9.67
Eisosomes -3.97 -1.34 -4.34 -3.27 -3.94 3.46 3.24 -5.13 -6.83 -6.73 1.25 3.05 -5.91 -6.94 -7.78
Endoplasmic Reticulum 1.76 -0.17 2.67 2.57 1.90 1.24 2.74 0.81 -0.94 -5.61 -0.31 1.42 1.18 2.04 -0.72
Endosome 3.41 3.10 4.18 2.16 2.20 -8.31 1.17 -2.72 6.71 -3.80 -6.91 2.48 -1.34 6.28 -4.53
Golgi 2.47 4.62 3.61 3.85 -3.45 -7.88 9.63 2.99 9.61 -5.11 -6.21 10.49 3.37 9.69 -7.32
Lipid Particles -5.06 -0.09 -0.10 6.65 0.00 -2.28 3.64 0.29 2.50 -3.19 -5.48 3.49 1.00 6.76 -3.05
Mitochondria -0.36 3.23 -0.61 -0.24 -6.37 -2.72 1.17 -1.19 1.93 -2.54 -2.43 1.82 -1.55 1.31 -3.93
Mitotic Spindle 0.17 -5.88 0.05 -0.25 6.58 -3.88 -12.20 -2.93 1.80 9.27 -4.58 -13.55 -4.50 1.04 10.52
None -2.05 -1.75 -4.46 1.90 -0.51 3.68 3.77 3.66 -0.79 -6.83 3.02 3.76 3.66 1.84 -8.13
Nuclear Periphery 0.20 -2.23 0.48 0.71 4.00 -3.80 -9.98 -2.39 -0.91 0.59 -3.52 -8.12 -3.34 -0.17 2.29
Nuclear Periphery Foci -2.79 -2.78 1.24 3.84 2.86 2.55 3.48 2.08 -0.14 -0.79 1.60 0.47 3.04 2.12 2.33
Nucleolus -1.71 -1.58 0.43 1.72 1.58 1.10 2.19 2.73 1.09 0.79 -0.30 1.16 2.86 2.00 1.88
Nucleus -2.54 -1.95 0.73 2.70 2.00 2.66 2.96 2.92 1.36 -0.34 0.96 1.99 2.94 2.87 1.87
Peroxisomes -2.97 1.20 0.29 7.19 -1.58 1.00 -4.09 8.38 6.41 12.72 2.38 -2.55 12.35 9.66 16.74
Vacuole 0.19 -2.04 0.16 -0.06 2.15 -0.95 -0.12 -1.00 -0.73 -0.98 -1.48 -2.12 -2.19 -0.42 -0.42
Vacuole Periphery 1.52 1.55 1.35 -1.45 -1.84 -0.79 0.73 0.89 2.66 0.60 0.64 1.59 0.76 0.27 -1.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Peroxisomal membrane protein (PMP); required for proper localization and stability of PMPs; anchors peroxisome retention factor Inp1p at the peroxisomal membrane; interacts with Pex19p
Localization
Cell Percentages peroxisome (73%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pex3

Pex3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pex3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available