Standard name
Human Ortholog
Description Golgi-localized protein with homology to gamma-adaptin; interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi; GGA1 has a paralog, GGA2, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.06 0.07 0 0.13 0.07 0.06 0.06 – 0.07 0.06 0.07 0.05 0.05 0 0 0.08 0.1 0.08 0.06 0 0 0.06 0 0.05
Bud 0 0 0 0 0 0 0 – 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0.07 0 0 0 0 0 0
Cytoplasm 0.68 0.66 0.85 0.46 0.18 0.09 0.09 – 0.06 0.07 0.05 0.07 0.92 0.89 0.84 0.56 0.58 0.59 0.36 0.41 0.4 0.58 0.51 0.45
Endoplasmic Reticulum 0.05 0.15 0 0.07 0.06 0.09 0 – 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0
Endosome 0 0.05 0.06 0.11 0.25 0.22 0.28 – 0.17 0.18 0.06 0.15 0 0.07 0.09 0.06 0.06 0.07 0.19 0.14 0.06 0.09 0.13 0.13
Golgi 0 0.06 0 0.07 0.11 0.11 0.11 – 0.08 0.09 0.08 0.1 0 0 0 0.17 0.24 0.11 0 0.08 0 0 0 0
Mitochondria 0.21 0.05 0 0.13 0.17 0.44 0.38 – 0.56 0.53 0.75 0.62 0 0 0 0 0 0 0.19 0.12 0.31 0.12 0.13 0.17
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.09 0.14 0 0.09 – 0.06 0.07 0 0.07 0 0 0 0 0 0 0.05 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.13 0.05 0.08 – 0.12 0.12 0.07 0.09 0 0 0 0.15 0.14 0.15 0 0.11 0.09 0 0.06 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 12 10 3 15 17 18 22 – 22 20 24 16 6 7 3 11 20 14 16 4 3 3 4 8
Bud 3 2 0 3 5 8 13 – 26 10 16 11 1 0 0 1 0 0 2 2 3 0 2 4
Bud Neck 0 0 1 1 2 1 0 – 0 0 0 0 0 0 0 0 0 0 5 5 2 0 5 3
Bud Site 0 0 0 0 0 0 1 – 1 4 8 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 1 2 0 2 4 – 5 1 5 4 3 6 2 3 15 12 0 1 0 0 0 0
Cytoplasm 145 100 105 51 42 28 32 – 20 21 18 22 103 213 248 74 113 103 101 80 62 32 81 74
Endoplasmic Reticulum 11 22 4 8 13 28 8 – 9 9 5 6 0 6 3 4 10 8 7 6 3 1 2 2
Endosome 8 8 7 12 58 66 100 – 55 58 20 50 2 16 28 8 12 13 55 26 9 5 20 22
Golgi 2 9 1 8 25 34 40 – 25 29 28 33 0 2 9 22 48 20 11 16 1 0 2 3
Mitochondria 45 7 1 15 40 130 136 – 179 167 270 200 0 0 1 5 4 5 54 24 48 6 20 28
Nucleus 0 0 0 0 2 4 2 – 2 5 3 3 1 0 2 1 0 0 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 1 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 3 6 6 – 13 14 21 15 0 1 1 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 6 0 8 – 1 5 2 3 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 8 1 4 10 32 13 31 – 20 21 12 23 0 1 3 2 1 7 13 3 3 0 4 2
Vac/Vac Membrane 1 6 3 3 30 16 30 – 39 39 26 30 1 4 10 19 28 26 7 21 13 2 8 10
Unique Cell Count 213 151 124 112 233 297 354 321 314 362 325 112 240 295 131 196 175 284 199 155 56 160 167
Labelled Cell Count 236 166 130 128 275 354 434 417 403 458 419 117 256 310 151 251 208 284 199 155 56 160 167


Cytoplasm, Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 7.8 6.7 6.3 7.6 7.3 7.7 – 7.3 7.7 7.4 8.1 7.2 8.5 9.4 15.3 15.5 14.2 5.4 6.9 7.4
Std Deviation (1e-4) 0.6 1.4 0.9 1.2 1.3 1.0 1.2 – 1.5 1.5 1.9 1.9 1.3 1.3 1.6 3.6 3.9 3.0 0.9 1.2 1.5
Intensity Change (Log2) – – – -0.07 0.2 0.12 0.21 – 0.14 0.21 0.16 0.28 0.12 0.35 0.5 1.2 1.22 1.09 -0.29 0.05 0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 3.2 1.9 1.6 1.6 – 1.8 1.7 1.8 1.2 0 0 0 2.1 2.6 2.1
Bud 0 0 0 0 – 3.3 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 2.7 2.5
Cytoplasm -6.3 -12.2 -15.1 -16.0 – -16.5 -16.2 -17.6 -16.4 1.7 1.1 -0.2 -4.9 -5.1 -4.8
Endoplasmic Reticulum 1.4 1.0 2.2 0 – 0 0 0 0 0 0 0 0 0.8 0
Endosome 1.4 4.5 4.1 5.2 – 3.1 3.4 -0.1 2.8 0 0.4 1.3 0.2 0.2 0.6
Golgi 0 3.4 3.6 3.6 – 2.8 3.1 2.8 3.3 0 0 0 4.5 5.7 3.5
Mitochondria 3.8 4.6 8.7 8.0 – 10.6 10.2 14.3 11.6 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 2.7 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 1.9 3.1 0.5 2.0 – 1.3 1.4 0 1.5 0 0 0 0 0 0
Vacuole 0 3.2 1.3 2.3 – 3.1 3.2 1.9 2.5 0 0 0 3.4 3.5 3.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.569 2.8717 2.4642 2.5876 2.0593 3.033 1.5205 2.5369 1.9555 1.993 1.4392 1.818 1.0317 1.8875 1.4266 1.0907 0.9563 1.4021
Actin 0.0172 0.0024 0.0033 0.0207 0.001 0.0033 0.0225 0.0062 0.0042 0.0019 0.0013 0.005 0.0382 0.0027 0.0122 0.0075 0.052 0.0024
Bud 0.0015 0.0043 0.0041 0.0025 0.0017 0.0008 0.0017 0.0015 0.0014 0.0063 0.0016 0.0005 0.0004 0.0006 0.0014 0.0017 0.0062 0.0047
Bud Neck 0.0042 0.0009 0.0017 0.0009 0.0008 0.0022 0.0041 0.0005 0.002 0.0027 0.0006 0.0052 0.001 0.0004 0.0007 0.0011 0.0117 0.0023
Bud Periphery 0.001 0.0064 0.0059 0.0043 0.0014 0.0007 0.0017 0.0014 0.0013 0.0045 0.0014 0.0003 0.0003 0.0002 0.0005 0.001 0.0044 0.0046
Bud Site 0.0162 0.0155 0.0099 0.0049 0.0017 0.0007 0.0056 0.009 0.0094 0.0022 0.0023 0.0006 0.0031 0.0037 0.0072 0.0019 0.0308 0.0004
Cell Periphery 0.0005 0.0004 0.0004 0.0004 0.0002 0.0001 0.0006 0.0004 0.0014 0.0003 0.0003 0.0001 0.0006 0.0001 0.0001 0.0001 0.0013 0.0001
Cytoplasm 0.3308 0.4855 0.4657 0.4084 0.4354 0.3937 0.4211 0.6474 0.6413 0.4926 0.6648 0.476 0.372 0.6114 0.5817 0.5545 0.4878 0.5039
Cytoplasmic Foci 0.1445 0.1452 0.1392 0.1366 0.1305 0.1663 0.1412 0.1039 0.0769 0.085 0.0809 0.1637 0.1484 0.1223 0.094 0.0756 0.0709 0.12
Eisosomes 0.0003 0 0.0001 0.0001 0 0 0.0003 0 0.0001 0.0001 0 0 0.0007 0 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0134 0.0032 0.0046 0.0036 0.0065 0.0059 0.0193 0.0059 0.006 0.0028 0.0015 0.0058 0.0165 0.0037 0.0072 0.0038 0.0053 0.0065
Endosome 0.294 0.2237 0.2141 0.2673 0.3423 0.2882 0.21 0.149 0.1569 0.2252 0.1115 0.2444 0.2834 0.1881 0.2167 0.2624 0.2202 0.2777
Golgi 0.0392 0.0284 0.0286 0.024 0.0277 0.0528 0.0255 0.029 0.0243 0.0518 0.0112 0.0343 0.0416 0.0193 0.0278 0.0302 0.0353 0.0396
Lipid Particles 0.009 0.0016 0.0033 0.0058 0.0007 0.0011 0.0225 0.0012 0.0051 0.0065 0.0064 0.0064 0.0168 0.0008 0.0022 0.002 0.0107 0.0011
Mitochondria 0.0138 0.009 0.0077 0.0056 0.0063 0.0355 0.0103 0.0159 0.0057 0.0814 0.0027 0.0069 0.0061 0.001 0.0035 0.0188 0.0057 0.006
None 0.0813 0.0477 0.0902 0.0728 0.0151 0.0314 0.0563 0.0177 0.031 0.01 0.101 0.0328 0.0358 0.0313 0.0324 0.0163 0.0225 0.0172
Nuclear Periphery 0.0069 0.0014 0.0014 0.0029 0.0018 0.0006 0.0079 0.0006 0.001 0.0009 0.0007 0.0007 0.0083 0.0007 0.0011 0.0011 0.0013 0.0007
Nucleolus 0.0005 0.0004 0.0003 0.0004 0.0001 0.0001 0.001 0.0001 0.0025 0.0003 0.0001 0.0001 0.0007 0.0001 0 0.0001 0.0027 0
Nucleus 0.005 0.0022 0.0019 0.0021 0.0017 0.001 0.0087 0.0008 0.0017 0.0013 0.0008 0.0006 0.0021 0.0008 0.0007 0.0013 0.0024 0.0009
Peroxisomes 0.0069 0.0035 0.0037 0.0089 0.0015 0.0039 0.0133 0.0016 0.0068 0.0027 0.005 0.0078 0.0057 0.0012 0.0015 0.0026 0.0051 0.0027
Punctate Nuclear 0.0019 0.0025 0.0011 0.0072 0.0005 0.0005 0.0067 0.0004 0.0004 0.0009 0.0009 0.001 0.0102 0.0004 0.0006 0.0004 0.0006 0.0005
Vacuole 0.0092 0.0127 0.0102 0.0157 0.016 0.0076 0.0163 0.0064 0.0174 0.0153 0.0038 0.0053 0.0061 0.0092 0.0062 0.0123 0.0184 0.0061
Vacuole Periphery 0.0029 0.003 0.0029 0.0047 0.0072 0.0036 0.0033 0.0013 0.0032 0.0053 0.0013 0.0024 0.0022 0.0019 0.0023 0.0054 0.0044 0.0027

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.9323 9.4277 8.3075 14.9822 4.7003 11.1992 10.7239 15.2801 18.261 12.966
Translational Efficiency 1.2901 1.1282 1.7348 1.7978 2.6229 1.8544 1.8156 2.0 1.9531 1.792

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
331 199 1323 1037 1608 1266 446 1402 1939 1465 1769 2439

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.27 868.59 1257.15 1168.58 807.33 801.75 1198.43 1129.88 798.10 810.83 1242.35 1146.33
Standard Deviation 99.84 123.27 183.83 198.32 101.02 115.42 171.07 181.29 102.85 118.74 182.49 189.69
Intensity Change Log 2 — 0.205508 0.738918 0.633518 — -0.010006 0.569915 0.484939 — 0.098041 0.653963 0.558567

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000991 0.001440 0.002609 0.001393 0.000965 0.000996 0.006466 0.001631 0.000969 0.001056 0.003582 0.001530
Bud Neck 0.018626 0.016951 0.001853 0.004460 0.012054 0.014049 0.004663 0.003120 0.013176 0.014443 0.002562 0.003690
Bud Site 0.036355 0.043084 0.041356 0.049287 0.028761 0.032409 0.060163 0.053067 0.030057 0.033859 0.046098 0.051460
Cell Periphery 0.000223 0.000107 0.000156 0.000096 0.000123 0.000136 0.000088 0.000122 0.000140 0.000132 0.000139 0.000111
Cytoplasm 0.101553* 0.346884* 0.082565 0.377597* 0.239769* 0.252605* 0.130756* 0.512290* 0.216174* 0.265412* 0.094715 0.455022*
Cytoplasmic Foci 0.393322* 0.383925* 0.235050* 0.210367* 0.450484* 0.421461* 0.333627* 0.206064* 0.440726* 0.416363* 0.259903* 0.207894*
Eisosomes 0.000157 0.000102 0.000017 0.000015 0.000143 0.000121 0.000032 0.000017 0.000146 0.000119 0.000021 0.000016
Endoplasmic Reticulum 0.000878 0.000499 0.002142 0.000593 0.002027 0.000735 0.000602 0.000300 0.001831 0.000703 0.001753 0.000424
Endosome 0.109693 0.051438 0.098473 0.081376 0.070471 0.092728 0.126145 0.055188 0.077166 0.087119 0.105450 0.066322
Golgi 0.181684* 0.022899 0.273891* 0.021811 0.093019 0.052831 0.048706 0.020193 0.108155 0.048765 0.217117* 0.020881
Lipid Particles 0.013620 0.001908 0.003465 0.003606 0.008160 0.005746 0.004436 0.002773 0.009092 0.005225 0.003710 0.003127
Mitochondria 0.044937 0.004504 0.002339 0.001284 0.017733 0.014994 0.000687 0.001757 0.022377 0.013569 0.001923 0.001556
Mitotic Spindle 0.022895 0.007125 0.150197* 0.050893 0.011677 0.012128 0.140487* 0.027287 0.013592 0.011449 0.147749* 0.037323
None 0.000729 0.000162 0.000077 0.000116 0.000541 0.000629 0.000146 0.000093 0.000573 0.000566 0.000095 0.000103
Nuclear Periphery 0.000080 0.000071 0.000620 0.000399 0.000110 0.000100 0.000237 0.000090 0.000105 0.000096 0.000524 0.000221
Nuclear Periphery Foci 0.000447 0.000362 0.009906 0.001366 0.000552 0.000304 0.002152 0.000727 0.000534 0.000312 0.007951 0.000999
Nucleolus 0.002319 0.000187 0.000045 0.000166 0.000393 0.000473 0.000195 0.000110 0.000721 0.000434 0.000083 0.000134
Nucleus 0.003858 0.007444 0.000558 0.002624 0.006401 0.005469 0.001675 0.001749 0.005967 0.005737 0.000840 0.002121
Peroxisomes 0.048783 0.018095 0.002729 0.009547 0.012298 0.016778 0.023642 0.010529 0.018526 0.016957 0.008002 0.010112
Vacuole 0.011523 0.088942 0.070819 0.169486 0.035593 0.065770 0.110239 0.096698 0.031484 0.068918 0.080757 0.127646
Vacuole Periphery 0.007327 0.003870 0.021132 0.013517 0.008727 0.009537 0.004856 0.006196 0.008488 0.008767 0.017028 0.009309

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.72 -3.47 -0.68 0.25 2.56 -0.08 -2.76 -1.43 -1.24 2.42 -0.29 -4.39 -1.52 -1.06 3.47
Bud Neck 0.50 6.17 5.17 4.05 -8.30 -1.55 6.77 9.81 11.42 4.04 -0.97 11.85 10.68 11.65 -3.93
Bud Site -0.86 -1.19 -2.11 -0.92 -1.68 -1.36 -6.24 -8.40 -6.32 1.48 -1.47 -6.71 -8.67 -6.35 -1.25
Cell Periphery 3.34 1.86 3.82 0.78 5.41 -0.53 2.99 0.29 0.67 -2.03 0.41 -0.09 2.64 1.13 3.02
Cytoplasm -12.04 1.36 -21.07 -1.92 -28.39 -1.39 8.05 -25.79 -23.24 -27.91 -5.70 16.55 -28.48 -20.71 -46.12
Cytoplasmic Foci 0.73 13.85 15.79 10.91 4.60 3.57 12.32 34.33 27.04 9.20 3.36 29.64 39.34 30.40 9.28
Eisosomes 3.11 10.78 10.95 6.56 1.82 1.07 5.68 6.56 12.59 4.11 1.56 7.72 8.04 13.98 3.50
Endoplasmic Reticulum 0.84 -2.53 0.79 -0.19 5.40 3.59 3.84 4.98 4.38 4.29 3.65 0.04 4.79 3.34 6.26
Endosome 6.01 1.39 4.12 -3.63 5.98 -5.46 -6.63 5.81 10.41 9.59 -2.51 -7.10 5.37 7.59 13.26
Golgi 13.12 -6.39 14.14 0.85 34.21* 9.45 9.86 19.96 11.69 5.42 14.16 -14.89 24.17 11.80 32.23*
Lipid Particles 5.23 4.45 4.27 -4.33 -0.67 2.58 3.36 6.62 3.63 3.06 4.42 7.12 7.81 2.92 1.70
Mitochondria 6.90 7.62 7.84 1.77 2.52 1.55 13.36 11.17 8.87 -1.25 4.79 13.97 14.04 9.67 1.02
Mitotic Spindle 3.19 -16.19 -4.83 -8.76 11.78 -0.23 -11.17 -5.55 -5.14 9.27 1.09 -23.08 -8.94 -9.35 16.98
None 3.90 4.59 4.26 0.79 -2.84 -0.61 5.45 7.86 3.48 0.58 0.11 9.76 9.18 3.51 -1.12
Nuclear Periphery 0.14 -5.18 -2.83 -2.92 1.64 0.39 -3.91 -0.60 -1.19 3.68 0.37 -5.67 -2.70 -2.97 3.55
Nuclear Periphery Foci 0.45 -7.46 -3.77 -3.90 6.63 2.25 -5.27 -2.01 -3.71 4.40 2.31 -7.98 -3.85 -5.68 7.33
Nucleolus 2.30 2.43 2.31 0.28 -9.19 -1.29 2.04 6.29 5.31 2.57 1.67 3.58 3.32 5.02 -3.17
Nucleus -2.92 4.25 0.74 3.53 -3.26 1.03 6.65 6.30 3.81 -0.25 0.18 11.12 5.60 4.22 -4.14
Peroxisomes 5.51 10.34 8.89 2.64 -8.43 -3.01 -3.57 2.41 5.13 4.79 0.97 8.83 7.72 6.12 -2.46
Vacuole -10.19 -18.02 -27.75 -8.93 -15.92 -9.09 -11.13 -17.39 -8.32 3.31 -12.30 -16.17 -29.13 -15.26 -9.91
Vacuole Periphery 2.42 -7.74 -2.14 -4.91 5.06 -0.86 4.74 3.66 3.85 -1.13 -0.27 -8.12 0.51 0.67 7.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Golgi-localized protein with homology to gamma-adaptin; interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi; GGA1 has a paralog, GGA2, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (49%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-3

Gga1

Gga1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gga1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available