Standard name
Human Ortholog
Description Essential protein involved in nuclear export of Mss4p; Mss4p is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.05
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.11 0.23 0.2 0.08 0.11 0.1 0.07 0.05 0.07 0.07 0.08 0.07 0.33 0.39 0.24 0.55 0.57 0.6 0 0.11 0.13 0.1 0.13 0.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.05 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.52 0.31 0.41 0.75 0.67 0.69 0.67 0.59 0.64 0.68 0.66 0.67 0.37 0.22 0.38 0 0.05 0.09 0.83 0.66 0.67 0.64 0.54 0.38
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.2 0 0 0 0.16 0.12 0.14 0.12 0.17 0 0 0 0 0 0 0 0 0 0 0 0.09
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.5 0.58 0.47 0 0.24 0.2 0.22 0.24 0.2 0.15 0.18 0.13 0.37 0.46 0.41 0.52 0.5 0.46 0.05 0.11 0.07 0.12 0.14 0.24
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Bud 0 0 0 0 0 1 0 2 0 1 2 4 0 0 0 0 0 1 3 6 17 9 19 14
Bud Neck 0 0 0 0 0 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 2 0 1 1 3 2 12 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 13 39 94 31 47 55 55 34 36 37 43 43 38 79 44 182 159 161 4 20 69 17 40 30
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 2 0 0 1 0 1 0 15 4 5 0 0 4 0 0 3
Endosome 0 0 2 0 2 1 11 6 1 4 3 3 1 5 3 2 0 0 0 2 3 2 4 13
Golgi 0 0 8 0 12 3 6 10 1 2 3 2 1 0 3 8 20 8 0 0 4 0 1 0
Mitochondria 0 2 0 1 1 1 5 4 27 10 15 31 0 0 0 5 1 1 0 2 1 1 3 9
Nucleus 64 52 195 284 281 394 497 417 343 371 367 419 43 45 70 12 15 25 109 126 346 111 162 115
Nuclear Periphery 0 0 0 2 0 0 3 2 2 2 1 0 0 0 0 0 0 0 0 1 4 1 1 3
Nucleolus 1 1 0 74 5 24 33 111 62 76 65 104 1 1 3 2 1 1 3 1 11 4 12 25
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0 2
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 1 2 7 3 5 3
Vac/Vac Membrane 61 97 225 10 99 117 165 166 107 83 100 82 43 94 75 170 140 122 6 21 34 20 41 73
Unique Cell Count 123 167 475 377 419 571 738 702 539 549 552 629 116 204 182 329 278 267 131 190 516 174 302 301
Labelled Cell Count 139 191 524 402 447 599 777 754 582 590 602 704 130 227 199 396 341 324 131 190 516 174 302 301


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 20.5 13.0 18.7 20.6 16.1 15.0 14.2 13.8 12.7 12.8 13.1 12.3 16.9 16.6 15.9 20.1 25.2 26.6 18.2 18.0 16.9
Std Deviation (1e-4) 4.3 3.4 4.2 8.9 4.0 4.4 3.5 3.5 3.7 3.6 3.7 3.9 4.3 3.8 4.0 5.1 7.0 7.8 5.1 4.9 5.4
Intensity Change (Log2) – – – 0.14 -0.21 -0.32 -0.4 -0.44 -0.55 -0.54 -0.51 -0.6 -0.14 -0.17 -0.24 0.11 0.43 0.51 -0.04 -0.06 -0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 3.0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -4.7 -3.5 -4.7 -6.4 -8.1 -6.2 -6.2 -5.6 -6.5 3.0 5.2 1.2 10.4 10.5 11.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 4.7 0 0
Endosome 0 0 0 1.8 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 1.2 0 -1.4 -0.4 0 0 -1.8 0 0 0 0 0.7 3.9 1.2
Mitochondria 0 0 0 0 0 4.9 0 3.6 4.9 0 0 0 0 0 0
Nucleus 10.0 7.8 9.1 9.0 6.2 7.2 8.5 8.2 8.5 -0.8 -4.7 -0.6 -11.9 -10.5 -9.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 10.1 0 4.5 4.7 9.1 7.6 8.4 7.7 9.3 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -14.5 -7.4 -9.2 -9.1 -8.5 -9.3 -11.2 -10.0 -12.6 -2.0 -0.3 -1.4 1.2 0.8 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 17.1238 21.4003 19.1122 18.0306 17.7343 19.8422 16.9653 22.282 19.7259 20.296 20.3432 21.1975 16.4911 20.9051 18.7897 18.1112 17.9891 18.0984
Actin 0.0133 0.0006 0.0079 0.0019 0.0014 0.0002 0.0369 0.0001 0.0245 0.0021 0.0004 0.0001 0.0153 0.0001 0.0047 0.0126 0.0271 0.0029
Bud 0.001 0.0004 0.0006 0.0003 0.001 0.0003 0.0012 0.0001 0.0009 0.0001 0.0001 0.0001 0.001 0.0001 0.0002 0.0002 0.0003 0.0006
Bud Neck 0.0008 0.0002 0.0004 0.0002 0.0012 0.0013 0.0013 0.0002 0.0015 0.0005 0.0001 0.0008 0.0011 0.0001 0.0004 0.0004 0.0004 0.0018
Bud Periphery 0.0011 0.0001 0.0006 0.0004 0.0014 0.0002 0.0014 0 0.0011 0.0002 0 0.0001 0.0018 0 0.0002 0.0001 0.0004 0.001
Bud Site 0.0015 0.0005 0.002 0.0005 0.0011 0.0001 0.0062 0.0002 0.0065 0.0015 0.0002 0.0001 0.0016 0.0004 0.0008 0.0003 0.0013 0.0011
Cell Periphery 0.0004 0 0.0001 0.0002 0.0004 0.0001 0.0003 0 0.0002 0.0006 0 0 0.0004 0 0 0 0 0.0001
Cytoplasm 0.0969 0.0627 0.074 0.0567 0.0686 0.047 0.1022 0.0886 0.066 0.0205 0.0156 0.0721 0.0851 0.0597 0.054 0.1092 0.0645 0.0671
Cytoplasmic Foci 0.0109 0.0002 0.0078 0.0074 0.0115 0.0006 0.0191 0.0002 0.0118 0.0013 0.0116 0.0005 0.0071 0 0.0077 0.0066 0.0035 0.0013
Eisosomes 0.0001 0 0.0001 0.0001 0 0 0.0002 0 0.0001 0.0022 0 0 0.0001 0 0.0002 0.0001 0.0001 0
Endoplasmic Reticulum 0.0046 0.0002 0.0005 0.0041 0.0031 0.0015 0.0036 0.0004 0.0059 0.001 0.0008 0.0005 0.0038 0.0002 0.0007 0.0002 0.0001 0.001
Endosome 0.0156 0.0001 0.0045 0.0119 0.026 0.0037 0.018 0.0001 0.0321 0.0003 0.0051 0.0009 0.0115 0 0.0043 0.001 0.001 0.0014
Golgi 0.0139 0 0.003 0.0047 0.0093 0.0002 0.0082 0 0.0097 0.0002 0.0017 0.0001 0.0044 0 0.002 0.001 0.0036 0.0009
Lipid Particles 0.0161 0 0.0054 0.0146 0.0032 0.0004 0.0088 0 0.0063 0.001 0.0264 0.0006 0.006 0 0.0024 0.003 0.0007 0.005
Mitochondria 0.0082 0.0004 0.0039 0.0191 0.0403 0.0009 0.0075 0.0001 0.0157 0.0004 0.001 0.0013 0.0127 0.0001 0.0018 0.0005 0.0076 0.0037
None 0.0014 0.0001 0.0005 0.001 0.0006 0.0002 0.0022 0.0001 0.0011 0.0554 0.0003 0.0003 0.0161 0 0.0011 0.0026 0.0001 0.0002
Nuclear Periphery 0.0212 0.0104 0.01 0.0261 0.0212 0.0135 0.0358 0.0089 0.0219 0.0052 0.0194 0.013 0.0272 0.0088 0.006 0.0102 0.0078 0.0105
Nucleolus 0.0049 0.0067 0.009 0.0103 0.004 0.0093 0.0142 0.0028 0.013 0.001 0.0019 0.0044 0.0044 0.0028 0.0011 0.0007 0.0043 0.0031
Nucleus 0.767 0.9152 0.8589 0.8273 0.77 0.9153 0.7012 0.8961 0.7681 0.9048 0.9023 0.9017 0.7598 0.9242 0.8987 0.8305 0.8693 0.8944
Peroxisomes 0.0115 0 0.0045 0.0036 0.0011 0 0.0036 0 0.0035 0.0005 0.0013 0 0.0246 0 0.0117 0.0107 0.0068 0.0007
Punctate Nuclear 0.0027 0.0017 0.0042 0.0013 0.0089 0.0014 0.0145 0.0009 0.0018 0.0008 0.0106 0.0013 0.0046 0.0027 0.0016 0.0096 0.0008 0.0012
Vacuole 0.0051 0.0003 0.0014 0.0028 0.0195 0.0023 0.0067 0.001 0.004 0.0003 0.0005 0.0014 0.0082 0.0006 0.0003 0.0003 0.0002 0.0014
Vacuole Periphery 0.0018 0.0001 0.0005 0.0053 0.0064 0.0015 0.0068 0.0001 0.0041 0.0001 0.0007 0.0008 0.0033 0.0001 0.0002 0.0001 0.0001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 77.057 67.1477 64.4308 54.2778 62.1275 41.4195 48.2859 37.5276 42.8898 56.3215
Translational Efficiency 1.8073 2.021 1.8126 1.7421 1.7266 2.2211 2.037 2.3267 1.7082 1.7347

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1985 1038 2009 1998 1722 2182 3182 2237 3707 3220 5191 4235

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1350.90 1451.82 1756.31 1815.40 1360.75 1565.06 1970.18 2025.73 1355.48 1528.56 1887.41 1926.50
Standard Deviation 241.85 398.22 264.65 363.76 243.38 244.71 336.87 412.81 242.61 307.41 327.90 404.31
Intensity Change Log 2 — 0.103942 0.378627 0.426367 — 0.201816 0.533925 0.574040 — 0.153886 0.458646 0.502360

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000379 0.000637 0.000117 0.000718 0.000444 0.000452 0.000209 0.000483 0.000410 0.000512 0.000173 0.000594
Bud Neck 0.011400 0.014544 0.004277 0.033649 0.016985 0.014792 0.013389 0.032906 0.013995 0.014712 0.009862 0.033256
Bud Site 0.001700 0.004454 0.000454 0.006540 0.001948 0.003595 0.001000 0.002875 0.001815 0.003872 0.000789 0.004604
Cell Periphery 0.000379 0.000529 0.000066 0.000302 0.000330 0.000270 0.000104 0.000160 0.000356 0.000354 0.000089 0.000227
Cytoplasm 0.019048 0.054986 0.073720 0.012877 0.019225 0.035534 0.021718 0.008488 0.019130 0.041805 0.041843 0.010559
Cytoplasmic Foci 0.000142 0.000863 0.000124 0.002123 0.000401 0.001220 0.000038 0.000725 0.000262 0.001105 0.000072 0.001384
Eisosomes 0.000026 0.000023 0.000003 0.000025 0.000028 0.000023 0.000013 0.000025 0.000027 0.000023 0.000009 0.000025
Endoplasmic Reticulum 0.003173 0.001854 0.000385 0.000941 0.003203 0.002123 0.000583 0.000904 0.003187 0.002036 0.000506 0.000921
Endosome 0.000204 0.000348 0.000045 0.003165 0.000261 0.001008 0.000098 0.000981 0.000230 0.000795 0.000078 0.002011
Golgi 0.000053 0.000280 0.000026 0.001046 0.000095 0.000535 0.000037 0.000419 0.000073 0.000453 0.000033 0.000715
Lipid Particles 0.000027 0.000099 0.000041 0.000218 0.000063 0.000109 0.000018 0.000080 0.000044 0.000105 0.000027 0.000146
Mitochondria 0.000811 0.001190 0.000913 0.002984 0.000920 0.001253 0.001027 0.002029 0.000861 0.001233 0.000983 0.002480
Mitotic Spindle 0.000366 0.005088 0.000350 0.038011 0.001319 0.003972 0.004077 0.008810 0.000808 0.004332 0.002634 0.022586
None 0.004153 0.010376 0.004525 0.008875 0.002809 0.005300 0.004417 0.003844 0.003529 0.006936 0.004459 0.006218
Nuclear Periphery 0.000356 0.000389 0.000696 0.001400 0.000478 0.000470 0.000613 0.000786 0.000413 0.000444 0.000645 0.001076
Nuclear Periphery Foci 0.000138 0.001146 0.000033 0.002040 0.000324 0.000286 0.000156 0.000764 0.000225 0.000563 0.000108 0.001366
Nucleolus 0.001662 0.003377 0.000249 0.011005 0.005840 0.004153 0.000676 0.011319 0.003603 0.003903 0.000511 0.011171
Nucleus 0.954499* 0.896307* 0.912551* 0.867123* 0.943181* 0.919702* 0.951076* 0.921959* 0.949242* 0.912161* 0.936167* 0.896089*
Peroxisomes 0.000066 0.000111 0.000008 0.000462 0.000164 0.000635 0.000017 0.000320 0.000111 0.000466 0.000014 0.000387
Vacuole 0.001329 0.003005 0.001388 0.004671 0.001787 0.003766 0.000686 0.001427 0.001542 0.003520 0.000958 0.002957
Vacuole Periphery 0.000088 0.000393 0.000028 0.001826 0.000195 0.000804 0.000047 0.000695 0.000138 0.000671 0.000040 0.001229

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.67 5.40 -10.17 -1.76 -14.96 -0.66 9.06 -5.34 -4.27 -15.23 -4.68 9.41 -11.28 -5.12 -21.45
Bud Neck -3.58 7.20 -13.15 -7.73 -17.04 1.43 0.12 -12.92 -13.74 -13.20 -2.14 1.83 -18.72 -15.71 -19.85
Bud Site -3.33 3.46 -6.91 -0.44 -8.44 -2.67 4.66 -4.00 0.36 -7.67 -4.35 5.59 -8.04 -0.44 -11.26
Cell Periphery -1.64 7.91 4.44 3.79 -5.60 1.29 6.87 5.35 2.15 -2.21 0.24 10.34 6.94 3.85 -5.46
Cytoplasm -7.77 -19.08 3.40 9.35 24.00 -5.95 0.39 6.37 11.46 9.79 -9.73 -12.44 7.08 14.47 23.57
Cytoplasmic Foci -4.49 -1.18 -3.26 0.55 -0.61 -2.38 3.73 0.16 2.24 -2.21 -4.04 0.55 -2.02 2.16 -2.02
Eisosomes 1.04 14.37 -0.49 -1.72 -23.22 2.96 9.19 0.02 -3.61 -12.57 2.90 15.28 -0.39 -3.99 -22.65
Endoplasmic Reticulum 4.86 12.07 9.38 5.47 -11.89 6.35 19.55 16.00 11.77 -9.34 7.07 19.57 15.80 12.79 -14.76
Endosome -2.24 4.44 -3.05 -2.37 -3.54 -3.19 6.13 -1.48 1.70 -2.76 -3.65 7.04 -3.41 0.02 -4.46
Golgi -2.34 0.99 -3.33 -0.93 -3.49 -2.19 1.87 -1.49 1.08 -1.99 -2.82 2.00 -3.39 0.55 -3.83
Lipid Particles -4.35 -4.92 -5.19 -0.14 -2.01 -1.16 2.32 -0.11 1.30 -3.57 -3.77 0.27 -3.20 0.76 -4.24
Mitochondria -3.16 -2.58 -12.32 -11.36 -13.66 -1.87 -4.88 -12.25 -5.88 -11.04 -2.94 -5.16 -16.97 -9.74 -17.36
Mitotic Spindle -2.84 -2.12 -8.09 -5.23 -7.38 -2.60 -2.47 -4.64 -2.33 -2.71 -4.19 -3.51 -9.38 -5.80 -7.33
None -3.58 -1.19 -4.09 1.36 -3.97 -4.39 -5.12 -2.45 1.91 1.43 -4.89 -3.58 -4.48 1.43 -2.40
Nuclear Periphery -2.13 -10.75 -9.22 -8.22 -4.26 -1.06 -5.18 -4.90 -4.26 -2.09 -2.78 -10.73 -10.11 -8.48 -4.58
Nuclear Periphery Foci -2.64 1.86 -1.89 1.06 -2.19 0.38 2.55 -0.00 -0.24 -1.51 -2.41 2.80 -1.45 0.42 -2.61
Nucleolus -2.26 4.57 -7.74 -5.98 -8.85 1.14 5.39 -4.75 -5.88 -8.75 -1.04 6.25 -8.85 -8.17 -12.30
Nucleus 9.63 12.79 13.16 0.34 4.47 5.83 -2.15 7.20 0.79 9.96 11.32 6.36 14.77 1.47 10.82
Peroxisomes -1.89 2.28 -3.40 -2.51 -4.47 -1.75 3.73 -1.07 1.33 -3.52 -2.02 4.35 -2.83 1.09 -5.38
Vacuole -3.58 -4.05 -5.18 -1.43 -3.46 -3.76 2.52 -0.75 3.28 -3.32 -5.22 -0.17 -4.76 1.58 -4.97
Vacuole Periphery -2.14 3.75 -3.26 -1.29 -3.56 -2.09 2.38 -1.44 1.17 -2.69 -2.71 3.18 -3.47 0.44 -4.44
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Essential protein involved in nuclear export of Mss4p; Mss4p is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport
Localization
Cell Percentages nucleus (52%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Bcp1

Bcp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bcp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available