Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.06 0.09 0.07 0.06 0.07 0.06 0 0 0 0 0.14 0.16 0.22 0.08 0.2 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0 0 0 0 0.19 0.15 0.08 0.23 0.18 0.43 0.22 0 0 0 0.06 0 0.06 0 0 0 0 0 0
Nucleus 0.94 0.92 0.95 0.85 0.81 0.74 0.76 0.84 0.71 0.74 0.64 0.71 0.8 0.82 0.73 0.8 0.69 0.77 0.84 0.82 0.79 0.79 0.7 0.64
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.07 0.13 0.1 0.21 0.19 0.29 0.24 0 0 0 0 0 0 0 0 0 0 0.09 0.1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0.09 0.05 0.05 0.07 0 0.05 0 0.05 0.08 0.1 0.06 0 0 0 0 0 0 0.05 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0.12 0.05 0.07 0.12 0.08 0.11 0.12
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 3 0 0 0 1 0
Bud 0 0 0 0 0 0 0 0 7 3 1 1 0 0 0 1 0 0 1 2 0 0 2 3
Bud Neck 0 0 0 0 1 0 1 5 2 2 2 1 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 1 0 4 8 7 7 14 14 5 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
Cytoplasm 7 8 8 11 13 15 20 29 8 12 4 6 23 37 57 5 25 9 2 2 0 1 2 8
Endoplasmic Reticulum 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 4 4 2 0 0 1 0 0 0
Endosome 0 2 0 1 6 5 5 1 0 4 0 1 1 1 5 2 5 1 1 3 1 0 5 3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 0 1 3 0 0 1
Mitochondria 20 10 0 5 4 44 46 42 60 56 101 59 3 0 0 4 5 5 0 5 1 0 3 5
Nucleus 248 219 133 106 153 175 228 425 185 235 148 190 132 193 185 52 85 66 237 212 121 81 164 189
Nuclear Periphery 0 0 0 2 1 1 7 1 4 1 4 1 0 0 0 0 1 1 0 0 0 0 0 1
Nucleolus 3 1 0 2 7 17 40 53 55 59 67 64 1 5 4 1 1 2 12 5 1 4 21 30
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 3 2 1 7 17 11 15 34 9 17 2 14 13 23 15 2 1 3 3 5 1 4 5 8
Vac/Vac Membrane 6 8 1 1 4 3 3 4 3 1 1 0 6 1 6 3 10 10 15 16 17 8 26 34
Unique Cell Count 265 239 140 124 189 236 301 507 260 317 233 267 165 236 254 65 124 86 283 260 154 103 236 295
Labelled Cell Count 287 251 143 136 207 275 373 601 342 405 344 342 179 260 274 76 137 101 283 260 154 103 236 295


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 5.4 6.4 6.2 6.5 5.5 5.5 5.8 5.1 5.4 4.7 5.3 6.2 6.1 6.0 6.5 7.0 6.6 6.7 6.3 6.7
Std Deviation (1e-4) 0.8 0.8 1.7 1.8 1.6 1.9 1.6 1.5 1.3 1.3 1.1 1.2 1.2 1.3 1.5 1.4 1.8 1.6 2.2 1.9 2.1
Intensity Change (Log2) – – – -0.04 0.03 -0.22 -0.21 -0.12 -0.33 -0.24 -0.44 -0.27 -0.03 -0.06 -0.09 0.03 0.14 0.05 0.08 -0.01 0.08


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 0.4 0.3 0.4 0 -1.3 -0.9 0 0 2.4 2.9 4.3 0 3.5 1.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 5.4 4.9 3.5 6.2 5.3 0 6.0 0 0 0 0 0 0
Nucleus -2.6 -3.7 -5.1 -4.9 -3.4 -5.6 -5.2 -6.8 -5.6 -3.9 -3.6 -5.3 -3.4 -5.7 -4.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 3.2 4.5 4.0 5.9 5.5 0 6.3 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 3.3 0 2.2 2.8 0 2.4 0 2.3 3.0 3.5 2.5 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 3.0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9517 0.2401 0.3441 0.5703 -0.2214 0.4748 0.3518 0.52 0.2993 0.269 0.4339 0.4062 1.1159 0.3282 0.3972 0.8834 0.9082 0.1223
Actin 0.0552 0.0089 0.0189 0.0009 0.0011 0.0155 0.0076 0 0.0122 0.0009 0.0061 0.0072 0.0217 0 0.0218 0.0142 0.0502 0
Bud 0.002 0.0003 0.0004 0.0004 0.0002 0.0004 0.0006 0 0.0002 0.0026 0.0006 0.0006 0.001 0.0001 0.0004 0.0019 0.0005 0
Bud Neck 0.0026 0.0004 0.0005 0.0003 0.0011 0.0018 0.005 0.0002 0.0003 0.0002 0.0008 0.0016 0.0033 0.0003 0.0006 0.0003 0.0034 0.0018
Bud Periphery 0.0025 0.0002 0.0006 0.0026 0.0004 0.0005 0.0014 0 0.0007 0.004 0.0013 0.0004 0.0013 0.0001 0.0006 0.0075 0.001 0.0001
Bud Site 0.0176 0.0011 0.0041 0.0007 0.001 0.0004 0.0036 0.0001 0.0003 0.0017 0.001 0.0012 0.0137 0.0007 0.0025 0.0011 0.0041 0.0001
Cell Periphery 0.0005 0.0001 0.0003 0.0004 0.0002 0.0001 0.0003 0 0 0.001 0.0001 0.0001 0.0004 0 0.0002 0.0002 0.0004 0
Cytoplasm 0.0057 0.0101 0.0026 0.0003 0.0058 0.0105 0.0046 0.0027 0.0009 0.0207 0.0018 0.0018 0.0144 0.0018 0.0014 0.0044 0.0027 0.0001
Cytoplasmic Foci 0.0354 0.0041 0.0069 0.0001 0.0012 0.0059 0.0152 0 0.0036 0.0078 0.0059 0.0015 0.027 0.0016 0.0046 0.0083 0.0375 0
Eisosomes 0.0006 0 0.0001 0.0003 0.0001 0.0001 0.0003 0 0.0001 0.0003 0.0001 0.0002 0.0002 0 0.0002 0.0002 0.0005 0
Endoplasmic Reticulum 0.0142 0.0018 0.0016 0.0002 0.029 0.0054 0.0012 0.0002 0.0004 0.0011 0.003 0.0006 0.0051 0.0002 0.001 0.004 0.0026 0
Endosome 0.0546 0.0013 0.0099 0.0013 0.0322 0.0331 0.0169 0.0002 0.0089 0.0017 0.0449 0.0039 0.0422 0.0038 0.0053 0.0405 0.0322 0
Golgi 0.0224 0.0009 0.0132 0.0006 0.001 0.0216 0.0045 0 0.0036 0.0002 0.0106 0.0012 0.0197 0.0001 0.0067 0.024 0.0313 0
Lipid Particles 0.027 0.001 0.0126 0.0014 0.0036 0.0039 0.0301 0 0.0054 0.0048 0.0504 0.0023 0.0231 0.0003 0.0093 0.0038 0.0519 0
Mitochondria 0.0102 0.0005 0.0097 0.1046 0.0046 0.0512 0.0078 0.0001 0.0087 0.0143 0.0117 0.0009 0.0081 0.0003 0.0081 0.0122 0.0132 0.0159
None 0.0084 0.0107 0.0028 0.0004 0.0022 0.0007 0.02 0.0016 0.0334 0.0953 0.0018 0.0056 0.0021 0.0068 0.0009 0.0009 0.0028 0
Nuclear Periphery 0.0536 0.0121 0.0069 0.0027 0.0972 0.0113 0.0099 0.0062 0.0034 0.0015 0.0086 0.0041 0.0136 0.0022 0.0024 0.0099 0.0163 0.0005
Nucleolus 0.0257 0.028 0.0459 0.023 0.1492 0.0419 0.0206 0.0216 0.0209 0.0123 0.0932 0.0339 0.0158 0.0307 0.0327 0.0148 0.098 0.0452
Nucleus 0.5959 0.8908 0.8144 0.8556 0.6198 0.7886 0.8033 0.9518 0.8811 0.8177 0.6605 0.9127 0.7453 0.9407 0.8874 0.839 0.6007 0.9343
Peroxisomes 0.02 0.0124 0.0134 0.0006 0.0003 0.0016 0.0117 0 0.0104 0.0026 0.0147 0.001 0.0056 0 0.0031 0.0015 0.0202 0
Punctate Nuclear 0.0375 0.0147 0.0292 0.001 0.0348 0.0034 0.0315 0.015 0.0049 0.003 0.0728 0.0185 0.0294 0.0084 0.0098 0.0074 0.0269 0.0017
Vacuole 0.0052 0.0005 0.0037 0.0014 0.0089 0.001 0.0028 0.0002 0.0003 0.0048 0.0072 0.0004 0.0041 0.0016 0.0008 0.0015 0.0022 0.0001
Vacuole Periphery 0.0032 0.0002 0.0021 0.0012 0.006 0.0013 0.0013 0.0001 0.0005 0.0016 0.003 0.0002 0.003 0.0003 0.0004 0.0023 0.0014 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.657 14.6564 12.3258 10.3599 14.5258 12.5628 12.8432 12.0023 11.0509 15.806
Translational Efficiency 1.4681 0.7683 0.6629 0.992 0.8075 1.0652 0.9413 0.7405 0.8715 0.7063

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
216 1427 1467 1815 1529 2473 2022 1172 1745 3900 3489 2987

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 714.92 825.14 911.67 977.87 705.94 755.38 921.89 925.34 707.05 780.91 917.59 957.26
Standard Deviation 79.76 101.68 111.83 133.25 78.19 98.18 108.12 121.84 78.44 104.99 109.81 131.42
Intensity Change Log 2 — 0.206857 0.350730 0.451861 — 0.097657 0.385049 0.390438 — 0.153635 0.367883 0.421670

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000079 0.000224 0.000758 0.001322 0.000231 0.000243 0.000447 0.001716 0.000212 0.000236 0.000578 0.001477
Bud Neck 0.000870 0.006211 0.016845 0.035490 0.002835 0.006716 0.011875 0.027637 0.002592 0.006531 0.013965 0.032409
Bud Site 0.000171 0.000614 0.001442 0.014256 0.000588 0.002108 0.000911 0.013310 0.000537 0.001561 0.001134 0.013885
Cell Periphery 0.000076 0.000040 0.000049 0.000129 0.000067 0.000108 0.000070 0.000159 0.000068 0.000083 0.000062 0.000141
Cytoplasm 0.037251 0.008834 0.001421 0.011140 0.026499 0.021101 0.006729 0.012749 0.027830 0.016612 0.004497 0.011772
Cytoplasmic Foci 0.004008 0.000823 0.000030 0.004719 0.003816 0.003182 0.000151 0.003424 0.003840 0.002319 0.000100 0.004211
Eisosomes 0.000026 0.000015 0.000026 0.000027 0.000024 0.000020 0.000022 0.000036 0.000025 0.000018 0.000024 0.000031
Endoplasmic Reticulum 0.000998 0.002602 0.004392 0.007329 0.001486 0.001975 0.003624 0.008685 0.001426 0.002204 0.003947 0.007861
Endosome 0.000377 0.000521 0.000232 0.006927 0.000335 0.001265 0.000330 0.006403 0.000340 0.000993 0.000289 0.006721
Golgi 0.000074 0.000218 0.000082 0.008989 0.000325 0.000737 0.000066 0.003937 0.000294 0.000547 0.000073 0.007007
Lipid Particles 0.001095 0.000365 0.000101 0.000433 0.001408 0.001271 0.000114 0.000348 0.001369 0.000939 0.000108 0.000400
Mitochondria 0.002429 0.002304 0.001536 0.007348 0.002118 0.005757 0.000836 0.008850 0.002156 0.004494 0.001130 0.007937
Mitotic Spindle 0.000326 0.004172 0.001236 0.057624 0.003281 0.007413 0.001467 0.025284 0.002916 0.006227 0.001370 0.044935
None 0.023828 0.003558 0.001812 0.004096 0.015672 0.008806 0.004311 0.005875 0.016681 0.006886 0.003260 0.004794
Nuclear Periphery 0.004439 0.002100 0.000451 0.005913 0.000636 0.001615 0.000512 0.004107 0.001107 0.001793 0.000487 0.005204
Nuclear Periphery Foci 0.000481 0.000716 0.000111 0.003872 0.000563 0.000443 0.000117 0.000990 0.000553 0.000543 0.000114 0.002741
Nucleolus 0.037733 0.015384 0.009793 0.004194 0.037460 0.023620 0.007188 0.004998 0.037494 0.020606 0.008284 0.004510
Nucleus 0.884305* 0.949042* 0.958111* 0.801650* 0.900950* 0.909032* 0.959818* 0.851132* 0.898889* 0.923672* 0.959100* 0.821065*
Peroxisomes 0.000360 0.000513 0.000198 0.000425 0.000784 0.001353 0.000118 0.000737 0.000731 0.001045 0.000152 0.000547
Vacuole 0.000741 0.001279 0.001191 0.017644 0.000679 0.002544 0.001212 0.015538 0.000687 0.002081 0.001203 0.016818
Vacuole Periphery 0.000332 0.000466 0.000180 0.006472 0.000242 0.000690 0.000081 0.004085 0.000253 0.000608 0.000123 0.005536

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.22 -21.32 -13.36 -11.69 -4.65 0.07 -7.20 -7.17 -7.19 -5.42 -0.38 -12.60 -12.70 -12.84 -7.87
Bud Neck -8.77 -19.33 -23.19 -18.21 -8.60 -6.43 -15.60 -16.56 -14.06 -8.84 -8.36 -22.58 -27.15 -23.19 -13.20
Bud Site -4.46 -9.67 -10.31 -9.77 -8.27 -2.99 -3.52 -6.22 -4.91 -5.79 -3.00 -5.81 -11.34 -9.60 -10.21
Cell Periphery 1.86 1.20 -1.89 -9.77 -8.94 -1.86 0.10 -6.02 -1.08 -5.86 -0.91 1.21 -7.32 -3.01 -9.59
Cytoplasm 3.72 4.78 3.46 -1.40 -10.72 2.07 8.95 5.54 4.21 -4.02 4.79 11.10 7.38 3.91 -8.27
Cytoplasmic Foci 3.19 3.80 2.63 -1.72 -4.10 1.13 6.48 3.99 3.55 -2.86 2.98 7.37 4.61 2.59 -4.92
Eisosomes 3.82 -0.70 -3.35 -14.65 -5.37 3.36 0.17 -7.62 -11.08 -8.54 5.31 -0.99 -8.93 -17.22 -10.28
Endoplasmic Reticulum -5.13 -12.64 -18.64 -16.62 -10.91 -2.73 -15.44 -16.64 -15.47 -10.42 -5.53 -21.88 -26.85 -23.74 -15.51
Endosome -0.42 0.78 -4.86 -4.78 -5.63 -4.06 0.00 -3.97 -2.40 -3.95 -4.04 0.73 -6.60 -4.48 -6.71
Golgi -1.55 -1.99 -3.62 -3.42 -3.58 -1.51 2.74 -2.18 -1.42 -2.71 -1.28 2.61 -3.90 -3.40 -4.39
Lipid Particles 2.90 3.79 2.70 -0.83 -5.95 0.50 4.22 3.43 5.00 -5.76 1.64 4.72 3.68 4.49 -7.72
Mitochondria 0.04 0.38 -1.55 -4.60 -7.62 -4.22 3.05 -3.06 0.32 -4.38 -3.54 2.14 -5.24 -1.14 -8.56
Mitotic Spindle -3.03 -2.85 -10.55 -8.75 -9.68 -2.49 0.52 -5.89 -4.42 -6.36 -2.51 0.33 -10.74 -9.37 -11.58
None 3.73 4.06 3.62 -1.34 -7.21 4.76 8.64 7.74 3.83 -1.89 7.08 10.25 9.19 3.97 -3.82
Nuclear Periphery 0.57 1.00 -0.08 -2.80 -7.83 -4.80 -1.93 -3.84 -2.42 -3.64 -1.35 0.83 -4.89 -4.55 -8.09
Nuclear Periphery Foci -0.75 1.23 -2.68 -2.12 -4.29 1.16 3.99 -0.60 -1.57 -3.74 0.48 4.51 -2.66 -2.90 -5.10
Nucleolus 3.71 4.26 5.45 7.80 6.36 6.28 13.57 14.37 12.07 1.81 8.29 13.73 15.78 14.67 5.84
Nucleus -4.76 -4.79 2.67 15.86 17.12 -2.11 -11.68 3.89 5.82 13.47 -5.68 -12.58 6.81 13.94 22.05
Peroxisomes -0.44 2.10 1.80 1.26 -0.42 -1.37 3.05 1.91 3.66 -2.25 -0.83 3.02 2.40 4.15 -2.51
Vacuole -1.46 -4.10 -11.87 -11.28 -11.28 -4.69 -5.97 -9.42 -8.19 -8.55 -4.78 -7.30 -15.15 -13.68 -14.05
Vacuole Periphery -0.44 0.69 -3.43 -3.18 -3.92 -3.41 2.90 -3.12 -2.14 -3.46 -2.92 2.28 -4.82 -3.76 -5.19
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Tfc6

Tfc6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tfc6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available