Standard name
Human Ortholog
Description ATPase of the 19S regulatory particle of the 26S proteasome; one of ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0.05
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.07 0 0 0 0 0 0 0 0 0 0.05 0 0 0.11 0.11 0.16 0 0 0 0 0 0
Cytoplasm 0 0 0 0.08 0.06 0.07 0.05 0.07 0 0.05 0 0 0.14 0.26 0.23 0.08 0.1 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.08 0 0 0 0 0 0 0 0 0 0.08 0.06 0.06 0 0 0 0 0.06 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.33 0.37 0.4 0.54 0.44 0.41 0 0.09 0.05 0.07 0.08 0.07
Mitochondria 0.92 0.92 0.85 0.89 0.87 0.89 0.93 0.88 0.94 0.94 0.95 0.95 0.46 0.28 0.38 0.09 0.08 0.06 0.86 0.71 0.77 0.7 0.64 0.59
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.14 0.08 0.06 0 0.13 0.06 0.07 0.06 0.09 0.06 0.1 0.08 0.21 0.27 0.15 0.17 0.23 0.28 0 0 0 0.08 0.08 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 1 0 0 2 2 3 6 4 6 0 3 7 2 9 22
Bud 4 0 2 5 5 5 17 10 7 13 13 10 0 0 1 4 2 1 0 1 3 5 21 20
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 8
Bud Site 0 0 0 0 0 3 8 5 6 5 4 2 0 0 0 1 1 0 – – – – – –
Cell Periphery 3 1 18 3 3 2 3 4 1 3 4 2 13 11 13 17 17 18 0 0 1 0 0 2
Cytoplasm 5 0 11 16 15 25 28 33 17 25 15 19 35 116 83 13 15 6 1 0 0 8 8 9
Endoplasmic Reticulum 2 1 1 2 1 2 4 2 3 5 3 11 7 3 6 3 6 2 0 0 0 1 0 6
Endosome 6 0 20 2 10 3 3 16 2 2 1 1 19 28 23 4 4 3 6 4 9 11 15 21
Golgi 0 2 4 4 7 1 1 1 1 0 0 0 84 163 145 87 66 48 6 6 13 20 33 31
Mitochondria 168 48 215 183 226 332 546 420 375 453 329 437 117 123 136 14 12 7 157 51 203 211 280 272
Nucleus 0 0 1 0 0 7 7 8 5 2 7 2 1 3 1 1 2 2 0 0 0 1 3 2
Nuclear Periphery 3 0 9 4 8 29 21 8 11 8 10 13 2 2 1 4 3 4 1 0 0 1 3 3
Nucleolus 5 1 4 2 3 13 24 25 7 11 9 7 1 0 1 5 3 5 0 0 0 0 1 1
Peroxisomes 1 0 26 3 5 5 0 8 1 4 2 4 4 13 8 1 6 3 2 1 21 3 7 6
SpindlePole 4 1 6 1 3 2 12 8 10 14 7 9 2 5 11 0 2 2 2 0 0 5 9 8
Vac/Vac Membrane 26 4 16 3 33 22 41 27 34 31 34 35 54 121 53 27 34 32 2 1 0 24 36 36
Unique Cell Count 182 52 253 206 259 373 585 478 397 481 348 461 252 442 359 160 151 116 183 73 266 304 442 459
Labelled Cell Count 227 58 334 228 319 451 715 575 480 577 438 552 341 590 485 187 177 139 183 73 266 304 442 459


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 8.7 7.7 7.4 6.4 5.1 4.6 4.5 4.5 4.3 4.0 4.0 8.9 8.5 8.1 11.2 10.6 11.0 8.6 9.0 9.2
Std Deviation (1e-4) 2.0 3.1 2.5 2.9 2.1 1.9 1.6 1.4 1.5 1.4 1.4 1.3 2.5 2.5 2.3 2.2 2.2 2.4 2.5 2.5 2.7
Intensity Change (Log2) – – – -0.05 -0.26 -0.59 -0.72 -0.76 -0.76 -0.82 -0.92 -0.94 0.22 0.15 0.09 0.55 0.46 0.52 0.17 0.23 0.26


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.9 -3.4 -4.6 0 0 0 0 0 0 -0.9 -2.9 -1.9 1.2 1.4 2.5
Cytoplasm 1.5 0.7 1.2 0.3 1.4 0 0.5 0 -0.1 3.7 7.2 6.3 1.6 2.2 0.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -3.5 -1.9 -4.6 0 0 0 0 0 0 -0.2 -0.8 -0.7 -2.3 -2.2 -2.0
Golgi 0 0.9 0 0 0 0 0 0 0 9.4 10.5 11.0 12.6 10.8 10.2
Mitochondria 1.2 0.7 1.5 0 0 0 0 0 0 -9.1 -14.5 -11.6 -15.2 -15.1 -14.4
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.0 -0.3 2.2 0 0 0 0 0 0 -2.1 0 0 -0.6 0 0
Nucleolus 0 0 1.4 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes -3.9 -4.0 -5.1 0 0 0 0 0 0 -4.1 -4.0 -4.3 -3.9 -2.3 -2.5
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0.5 0 0 0
Vacuole -2.6 2.5 -0.2 0.4 -0.4 1.0 0.1 1.5 0.6 4.9 6.7 3.3 3.4 4.8 5.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.7238 1.9764 1.7081 0.9181 0.9861 1.779 1.5383 0.947 1.2111 0.9184 1.8297 0.9264 0.563 1.3955 1.1867 1.3967 0.7423 0.9347
Actin 0.0509 0.0253 0.0219 0.0467 0.0245 0.0059 0.0901 0.0088 0.0487 0.0397 0.0061 0.013 0.0573 0.0181 0.0106 0.0446 0.0199 0.0139
Bud 0.003 0.0067 0.008 0.0068 0.0033 0.0015 0.0025 0.0064 0.0056 0.0041 0.0052 0.0017 0.0032 0.0231 0.0102 0.0016 0.0438 0.0082
Bud Neck 0.0047 0.0025 0.0055 0.0013 0.0066 0.0061 0.0085 0.0009 0.0015 0.003 0.029 0.0068 0.0061 0.0016 0.0058 0.0007 0.0006 0.0052
Bud Periphery 0.0079 0.0126 0.0222 0.0285 0.0043 0.0041 0.0028 0.0078 0.0169 0.0068 0.0159 0.0054 0.0084 0.0339 0.0217 0.0041 0.059 0.0196
Bud Site 0.0238 0.0803 0.0368 0.0053 0.0063 0.002 0.022 0.033 0.0085 0.0099 0.0264 0.0011 0.016 0.0648 0.0284 0.0024 0.0039 0.0024
Cell Periphery 0.008 0.0045 0.0031 0.0025 0.0008 0.0019 0.0009 0.0027 0.0016 0.0016 0.0032 0.001 0.0012 0.0023 0.0017 0.0014 0.0012 0.0014
Cytoplasm 0.0684 0.1029 0.1107 0.1538 0.1354 0.1096 0.0395 0.0711 0.0694 0.0752 0.0087 0.0847 0.0587 0.081 0.078 0.0399 0.0323 0.0605
Cytoplasmic Foci 0.076 0.0849 0.0466 0.0849 0.0566 0.0708 0.1001 0.0794 0.0659 0.0752 0.065 0.0798 0.0932 0.0478 0.0586 0.0498 0.075 0.051
Eisosomes 0.0018 0.0009 0.001 0.0007 0.0002 0.0004 0.001 0.0018 0.0008 0.0008 0.0001 0.0003 0.0008 0.001 0.0004 0.0008 0.0003 0.0003
Endoplasmic Reticulum 0.0124 0.0074 0.0109 0.004 0.0016 0.0034 0.006 0.0042 0.0053 0.0056 0.0004 0.0038 0.0046 0.0031 0.0043 0.0029 0.001 0.0064
Endosome 0.0803 0.0819 0.0665 0.1083 0.0616 0.1091 0.1257 0.0888 0.0834 0.1224 0.09 0.1162 0.1273 0.0756 0.0882 0.0553 0.0827 0.1015
Golgi 0.0362 0.0518 0.0276 0.0192 0.0154 0.0658 0.071 0.0644 0.0499 0.0908 0.0406 0.0644 0.0651 0.0434 0.0418 0.0433 0.0258 0.0462
Lipid Particles 0.0437 0.0113 0.0083 0.0095 0.0023 0.026 0.0741 0.0068 0.0195 0.015 0.0063 0.0224 0.0333 0.0096 0.0155 0.0225 0.0028 0.0106
Mitochondria 0.3288 0.2778 0.4008 0.2753 0.4904 0.4225 0.2358 0.4019 0.4352 0.4343 0.5583 0.4036 0.3386 0.4188 0.452 0.4084 0.4818 0.5188
None 0.1576 0.1695 0.1784 0.1753 0.1569 0.1403 0.103 0.1806 0.1326 0.0624 0.0998 0.1379 0.1444 0.1185 0.1364 0.2548 0.1211 0.0926
Nuclear Periphery 0.0086 0.0014 0.0068 0.0017 0.0005 0.0006 0.0127 0.0012 0.0027 0.0022 0.0004 0.0031 0.0034 0.001 0.0013 0.0006 0.0003 0.0094
Nucleolus 0.0011 0.0017 0.0018 0.0023 0.0006 0.0004 0.0012 0.0008 0.0007 0.0009 0.002 0.0003 0.0009 0.0036 0.0011 0.0005 0.0017 0.0004
Nucleus 0.0151 0.0025 0.0034 0.0027 0.001 0.001 0.0122 0.0013 0.0018 0.0019 0.0023 0.0008 0.0015 0.0048 0.0016 0.0006 0.0009 0.0014
Peroxisomes 0.0311 0.0337 0.0079 0.0119 0.0172 0.0133 0.0563 0.0218 0.0354 0.0285 0.0211 0.0273 0.0215 0.023 0.0209 0.0597 0.0361 0.034
Punctate Nuclear 0.0031 0.0018 0.0036 0.0058 0.0006 0.0008 0.0091 0.0009 0.0012 0.0011 0.0024 0.0013 0.002 0.0018 0.0012 0.0009 0.0016 0.0011
Vacuole 0.0289 0.0338 0.0173 0.0444 0.009 0.0102 0.0187 0.0103 0.0091 0.0126 0.0146 0.0185 0.0084 0.0171 0.0149 0.0029 0.0049 0.0081
Vacuole Periphery 0.0085 0.0051 0.011 0.0091 0.0049 0.0045 0.0065 0.005 0.0041 0.0061 0.0021 0.0069 0.004 0.0062 0.0053 0.0023 0.003 0.007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 83.5912 67.4445 87.5818 100.0554 56.6909 71.9772 96.0903 93.6205 93.3701 83.1394
Translational Efficiency 1.5631 1.8167 1.5176 1.3786 1.8423 2.049 1.5428 1.4626 1.6286 1.45

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1691 1344 897 1316 1904 2138 862 1206 3595 3482 1759 2522

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 800.94 853.72 1085.16 1031.31 821.86 857.28 1164.22 1041.91 812.02 855.91 1123.90 1036.38
Standard Deviation 142.73 172.35 206.73 212.40 160.58 169.73 205.83 200.24 152.80 170.76 210.04 206.74
Intensity Change Log 2 — 0.092069 0.438142 0.364712 — 0.060874 0.502399 0.342266 — 0.076355 0.471042 0.353388

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000862 0.001613 0.004105 0.022304 0.001080 0.001459 0.004764 0.008591 0.000978 0.001519 0.004428 0.015747
Bud Neck 0.013671 0.025636 0.008797 0.006831 0.010574 0.013303 0.007211 0.007331 0.012031 0.018063 0.008020 0.007070
Bud Site 0.046576 0.064254 0.042987 0.150604* 0.045300 0.055287 0.042307 0.112760* 0.045900 0.058748 0.042653 0.132507*
Cell Periphery 0.001462 0.000945 0.000400 0.002260 0.001464 0.000945 0.000609 0.001507 0.001463 0.000945 0.000502 0.001900
Cytoplasm 0.036608 0.062394 0.027824 0.039341 0.041624 0.049389 0.018889 0.046153 0.039265 0.054409 0.023446 0.042599
Cytoplasmic Foci 0.041919 0.085626 0.037732 0.025069 0.047428 0.054535 0.034302 0.037398 0.044836 0.066536 0.036051 0.030965
Eisosomes 0.000097 0.000114 0.000080 0.000183 0.000090 0.000120 0.000089 0.000119 0.000093 0.000117 0.000085 0.000152
Endoplasmic Reticulum 0.000965 0.001001 0.002028 0.002113 0.001066 0.000752 0.002146 0.001877 0.001018 0.000848 0.002086 0.002001
Endosome 0.044932 0.081057 0.045629 0.022555 0.047303 0.065784 0.038885 0.042826 0.046187 0.071679 0.042324 0.032248
Golgi 0.038435 0.066038 0.054315 0.061269 0.040578 0.057434 0.051816 0.082741 0.039570 0.060755 0.053090 0.071537
Lipid Particles 0.003141 0.004110 0.002897 0.000564 0.004202 0.003141 0.001439 0.001215 0.003703 0.003515 0.002183 0.000875
Mitochondria 0.687457* 0.454339* 0.542768* 0.554482* 0.666797* 0.574006* 0.607386* 0.483067* 0.676515* 0.527816* 0.574434* 0.520332*
Mitotic Spindle 0.011367 0.031270 0.087239 0.032315 0.013370 0.027127 0.073517 0.048569 0.012428 0.028726 0.080515 0.040088
None 0.001966 0.001821 0.001008 0.000675 0.001871 0.001331 0.000805 0.001718 0.001916 0.001521 0.000908 0.001174
Nuclear Periphery 0.000149 0.000254 0.001710 0.000148 0.000235 0.000330 0.001931 0.000402 0.000195 0.000301 0.001818 0.000269
Nuclear Periphery Foci 0.000239 0.000749 0.001327 0.000245 0.000505 0.000435 0.001410 0.000835 0.000380 0.000556 0.001368 0.000527
Nucleolus 0.000627 0.001629 0.001356 0.000105 0.000695 0.001174 0.000818 0.000383 0.000663 0.001350 0.001092 0.000238
Nucleus 0.004753 0.011255 0.018258 0.004659 0.004724 0.005435 0.012539 0.004405 0.004738 0.007681 0.015455 0.004538
Peroxisomes 0.018199 0.032596 0.018197 0.022865 0.021386 0.025089 0.023551 0.021656 0.019887 0.027987 0.020821 0.022287
Vacuole 0.025430 0.052007 0.057617 0.034065 0.027298 0.040861 0.040356 0.058631 0.026419 0.045163 0.049158 0.045812
Vacuole Periphery 0.021147 0.021290 0.043727 0.017346 0.022408 0.022066 0.035231 0.037817 0.021815 0.021766 0.039564 0.027135

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.63 -3.43 -9.48 -9.10 -7.38 -2.09 -4.96 -6.47 -6.09 -2.67 -3.44 -5.72 -11.26 -10.80 -7.75
Bud Neck -4.72 2.75 4.15 8.12 1.56 -2.10 2.44 1.98 4.20 -0.32 -4.69 3.59 4.43 9.08 0.90
Bud Site -3.59 0.58 -14.34 -11.48 -14.29 -2.45 0.45 -10.55 -8.96 -10.10 -4.10 0.72 -17.78 -14.90 -17.39
Cell Periphery 2.99 7.59 -2.19 -3.88 -5.87 2.53 4.34 0.03 -2.02 -3.45 3.81 7.83 -1.67 -4.32 -6.74
Cytoplasm -5.48 1.24 -2.44 3.12 -3.27 -1.94 4.37 -2.77 -1.14 -6.39 -5.06 3.87 -3.60 1.16 -6.77
Cytoplasmic Foci -9.70 1.18 5.38 14.56 3.93 -2.06 3.64 2.81 4.97 -1.01 -8.04 3.45 5.91 13.98 1.99
Eisosomes -2.44 1.86 -7.90 -6.53 -9.45 -1.51 -0.08 -2.53 0.07 -2.32 -1.98 1.23 -7.58 -2.54 -8.24
Endoplasmic Reticulum -0.28 -4.98 -4.06 -3.99 0.54 2.44 -3.19 -3.33 -4.74 0.89 1.75 -5.45 -5.22 -6.30 1.02
Endosome -8.90 -0.02 8.58 16.79 7.95 -5.64 2.72 1.82 7.30 -0.92 -10.04 1.85 7.16 17.24 4.73
Golgi -6.84 -3.36 -4.85 1.40 -1.17 -5.19 -2.36 -8.08 -4.45 -5.14 -8.41 -4.04 -9.15 -2.38 -4.48
Lipid Particles -1.43 0.05 4.58 6.29 5.28 1.58 4.38 4.68 4.05 0.92 0.29 2.91 6.63 7.56 4.94
Mitochondria 17.17 10.18 10.99 -5.26 -0.23 7.82 4.82 14.25 7.75 7.37 16.66 10.60 17.61 2.57 4.89
Mitotic Spindle -7.39 -11.94 -7.96 -0.39 8.05 -6.44 -10.74 -9.26 -5.37 3.77 -9.79 -16.04 -12.10 -4.51 8.43
None 0.37 2.79 4.53 4.84 2.36 1.71 4.14 0.26 -0.36 -1.02 1.60 4.73 1.84 0.99 -0.48
Nuclear Periphery -2.65 -5.62 -0.65 1.93 5.53 -0.72 -2.28 -1.87 -0.66 2.00 -1.33 -4.19 -1.87 0.06 3.91
Nuclear Periphery Foci -1.49 -5.08 -1.51 1.26 4.66 0.43 -1.97 -0.89 -1.15 0.99 -1.11 -3.97 -1.02 -0.06 2.73
Nucleolus -3.81 -1.93 4.36 6.28 3.16 -1.69 -0.87 2.36 3.12 2.83 -3.52 -2.10 4.71 6.21 4.00
Nucleus -4.15 -5.57 -1.89 2.14 4.72 -0.80 -3.78 -1.58 -0.79 3.07 -3.36 -6.71 -2.48 0.65 5.59
Peroxisomes -5.08 0.08 -1.58 3.19 -1.51 -1.62 -0.82 -0.09 1.25 0.67 -4.60 -0.51 -1.14 2.88 -0.50
Vacuole -8.54 -9.14 -5.92 1.09 2.79 -5.59 -4.70 -9.60 -6.35 -4.66 -9.94 -9.91 -10.97 -4.07 -1.22
Vacuole Periphery -0.00 -6.46 2.33 2.35 7.75 0.21 -4.01 -4.75 -5.09 -0.53 0.09 -7.48 -2.48 -2.65 5.01
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description ATPase of the 19S regulatory particle of the 26S proteasome; one of ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B
Localization
Cell Percentages mitochondrion (92%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Rpt3

Rpt3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpt3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available