Standard name
Human Ortholog
Description DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.17 0.16 0.34 0.32 0.2 0.27 0.21 0.16 0.16 0.18 0.15 0.29 0.37 0.41 0.27 0.22 0.35 0.08 0 0.14 0.16 0.23 0.21
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.08 0.09 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Mitochondria 0.28 0 0 0.11 0 0.22 0.28 0.59 0.46 0.72 0.45 0 0 0 0 0.05 0.09 0 0 0 0.05 0 0
Nucleus 0.6 0.54 0.46 0.5 0.57 0.48 0.57 0.47 0.56 0.41 0.58 0.6 0.57 0.48 0.32 0.4 0.26 0.59 0.64 0.31 0.42 0.32 0.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.24 0.48 0.19 0.13 0.27 0.15 0.08 0.05 0.07 0.07 0.07 0.16 0.13 0.14 0.36 0.33 0.35 0.27 0.26 0.38 0.27 0.37 0.34
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 0 0 1 0 1 1 0 0 0 0 0 0 0 2 0 0 1
Bud 0 0 0 0 0 1 4 2 3 0 6 1 0 0 0 0 0 0 0 7 1 3 5
Bud Neck 0 0 0 0 1 0 3 1 2 1 1 1 0 0 0 0 0 0 0 1 0 1 3
Bud Site 0 0 0 0 0 2 1 10 2 2 4 0 0 0 0 0 0
Cell Periphery 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 20 13 37 48 39 67 89 38 53 38 47 18 61 70 34 18 16 10 3 23 13 56 46
Endoplasmic Reticulum 0 0 1 0 0 0 1 1 0 1 2 1 4 0 12 4 1 0 0 1 0 0 0
Endosome 0 0 2 2 1 1 6 1 1 0 2 0 1 3 9 7 4 0 0 2 2 1 1
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 2 3 0 0 1 0 0 1
Mitochondria 34 3 0 17 5 54 118 139 157 154 143 0 2 1 4 4 4 3 2 2 4 5 6
Nucleus 72 44 50 75 111 119 238 112 190 88 182 38 95 81 41 33 12 84 70 52 35 78 68
Nuclear Periphery 0 0 0 0 0 0 1 0 1 2 2 0 0 0 1 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 1 0 0 0 0 0 4 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 2 1 2 1 3 2 4 3 5 1 0 0 0 1 0 2 1 3 1 4 10
Vac/Vac Membrane 29 39 21 20 53 38 35 11 25 14 22 10 22 24 46 27 16 39 28 65 22 91 76
Unique Cell Count 120 81 108 150 194 248 420 236 340 214 316 63 167 169 127 83 46 143 111 173 85 249 226
Labelled Cell Count 155 99 114 164 212 284 499 317 440 303 417 71 185 180 152 97 56 143 111 173 85 249 226


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 5.1 5.5 5.3 5.7 4.4 4.6 3.7 4.1 3.8 4.0 5.7 5.4 5.6 7.4 7.4 7.5 5.3 5.2 5.5
Std Deviation (1e-4) 0.4 0.9 1.2 1.9 1.5 1.0 1.4 0.7 0.7 1.7 1.1 1.0 1.1 1.2 2.3 2.7 2.7 1.3 1.1 1.3
Intensity Change (Log2) -0.07 0.05 -0.33 -0.25 -0.59 -0.42 -0.53 -0.48 0.05 -0.04 0.02 0.42 0.42 0.43 -0.05 -0.09 -0.02


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 -2.7 -1.4 -2.8 -3.8 -4.2 -3.3 -4.4 -0.8 0.4 1.2 -1.2 -1.9 0.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 2.8 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 1.9 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.6 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.6 1.8 0.3 1.9 0.2 1.7 -0.9 2.0 1.8 1.7 0.3 -2.2 -0.9 -2.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.3 1.5 -1.0 -3.3 -4.4 -3.6 -3.5 -3.7 -0.6 -1.4 -1.2 2.8 2.1 2.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5745 -0.3848 -0.3823 -0.7589 -0.6608 -0.5811 -0.0438 0.1681 -0.2043 0.1528 -0.0202 -0.034 0.5408 0.2187 0.0245 0.0627 0.6207 -0.2175
Actin 0.0198 0.0003 0.0018 0.0005 0.0082 0.0005 0.0122 0.0004 0.0159 0.0069 0.015 0.0046 0.0251 0.0118 0.0182 0.0139 0.0285 0.0115
Bud 0.0005 0.0005 0.0005 0.0001 0.004 0.0001 0.0006 0.0002 0.0009 0.0009 0.0013 0.0001 0.0011 0.0001 0.0014 0.003 0.0009 0.0002
Bud Neck 0.0136 0.0005 0.0009 0.0009 0.0023 0.0078 0.0055 0.0007 0.0025 0.0046 0.0013 0.0042 0.0218 0.0004 0.004 0.0011 0.0128 0.0046
Bud Periphery 0.0007 0.0002 0.0022 0.0001 0.0021 0.0002 0.0011 0.0002 0.0049 0.0027 0.0046 0.0002 0.0014 0.0001 0.0018 0.0118 0.0017 0.0003
Bud Site 0.0195 0.0122 0.0045 0.0002 0.0015 0.0002 0.0113 0.0019 0.0026 0.0037 0.0013 0.0003 0.0172 0.0009 0.0057 0.0017 0.0024 0.0005
Cell Periphery 0.0005 0.0002 0.0008 0.0001 0.0002 0.0001 0.0003 0.0001 0.0004 0.0007 0.0002 0.0001 0.0008 0.0001 0.0003 0.0005 0.0003 0.0001
Cytoplasm 0.1124 0.1206 0.123 0.1135 0.0883 0.158 0.0989 0.1134 0.0865 0.0481 0.0912 0.0873 0.1007 0.126 0.1415 0.0608 0.1085 0.0818
Cytoplasmic Foci 0.0381 0.0038 0.0092 0.001 0.0266 0.0038 0.0119 0.0033 0.0083 0.0216 0.019 0.0028 0.0229 0.0107 0.0111 0.0082 0.0259 0.0039
Eisosomes 0.0003 0.0001 0.0002 0 0.0002 0.0001 0.0005 0.0001 0.0002 0.0003 0.0002 0.0001 0.0003 0.0001 0.0001 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.0108 0.0062 0.008 0.0083 0.0056 0.0041 0.007 0.0033 0.0051 0.0031 0.0043 0.0016 0.0131 0.0057 0.0066 0.008 0.0082 0.0042
Endosome 0.0391 0.0055 0.0143 0.0021 0.081 0.0141 0.0206 0.003 0.0102 0.0735 0.0438 0.0026 0.042 0.0096 0.0184 0.0179 0.075 0.0069
Golgi 0.0103 0.0001 0.0046 0 0.0331 0.0032 0.0038 0.0001 0.0055 0.0355 0.0213 0.0014 0.0092 0.0019 0.005 0.0025 0.057 0.0021
Lipid Particles 0.0341 0.0008 0.0128 0.0001 0.0417 0.0178 0.0142 0.0005 0.0034 0.0252 0.024 0.0076 0.0172 0.0011 0.0082 0.0026 0.0339 0.0017
Mitochondria 0.0057 0.0005 0.0113 0.0008 0.014 0.0165 0.0121 0.001 0.0074 0.0301 0.1214 0.0068 0.006 0.0005 0.0036 0.0133 0.0273 0.0019
None 0.1185 0.1739 0.1448 0.1114 0.2639 0.0968 0.1468 0.163 0.183 0.1678 0.0872 0.1235 0.051 0.1679 0.0785 0.0985 0.1064 0.058
Nuclear Periphery 0.0426 0.0301 0.0421 0.0308 0.0137 0.0136 0.0421 0.0199 0.0373 0.0267 0.02 0.0123 0.0278 0.0291 0.0254 0.0249 0.0333 0.0206
Nucleolus 0.0042 0.007 0.0067 0.0027 0.0054 0.0051 0.0075 0.0099 0.005 0.0078 0.0039 0.0077 0.0082 0.0032 0.0039 0.007 0.0033 0.0063
Nucleus 0.4759 0.5937 0.5681 0.7167 0.3486 0.6379 0.5473 0.6324 0.5718 0.4954 0.4902 0.691 0.5916 0.608 0.6218 0.7013 0.4111 0.7551
Peroxisomes 0.0254 0.0001 0.0028 0.0001 0.0172 0.0012 0.0144 0.0006 0.0094 0.0071 0.0203 0.0011 0.0102 0.0002 0.0065 0.0012 0.0232 0.0014
Punctate Nuclear 0.0211 0.0347 0.0359 0.0083 0.0362 0.0148 0.034 0.0428 0.0352 0.0235 0.0237 0.0436 0.019 0.0188 0.0317 0.0132 0.0319 0.0371
Vacuole 0.0054 0.0082 0.0041 0.0017 0.0042 0.0026 0.0056 0.0026 0.0035 0.0092 0.0036 0.0009 0.0115 0.0032 0.0052 0.0049 0.0051 0.0013
Vacuole Periphery 0.0015 0.0009 0.0012 0.0005 0.0017 0.0015 0.0025 0.0004 0.001 0.0055 0.0025 0.0004 0.0018 0.0007 0.0011 0.0037 0.003 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.3915 5.7136 4.6252 7.0994 6.0268 4.6458 7.3526 9.7477 9.7139 7.6919
Translational Efficiency 0.8276 0.6534 0.8607 0.5509 0.5273 1.1157 0.8749 0.4523 0.7147 0.5602

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1825 821 630 1553 1487 1938 1751 5 3312 2759 2381 1558

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 568.39 725.69 938.59 809.94 704.19 728.97 858.11 336.05 629.36 727.99 879.40 808.42
Standard Deviation 67.37 96.28 105.26 108.65 102.76 96.97 98.99 4.93 108.65 96.77 106.76 111.74
Intensity Change Log 2 0.352472 0.723614 0.510934 0.049895 0.285198 -1.067289 0.192926 0.497593 -0.151162

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000083 0.000538 0.000535 0.000564 0.000075 0.000389 0.000150 0.000145 0.000079 0.000434 0.000252 0.000563
Bud Neck 0.008739 0.017797 0.004910 0.011691 0.002021 0.009099 0.005883 0.000054 0.005722 0.011687 0.005626 0.011654
Bud Site 0.008055 0.005563 0.004443 0.013070 0.000759 0.005581 0.002190 0.000057 0.004779 0.005575 0.002786 0.013029
Cell Periphery 0.000618 0.000190 0.000109 0.000280 0.000108 0.000167 0.000135 0.002011 0.000389 0.000174 0.000128 0.000286
Cytoplasm 0.328395* 0.179940* 0.039227 0.233275* 0.179847* 0.191374* 0.103597* 0.000489 0.261701* 0.187972* 0.086565 0.232528*
Cytoplasmic Foci 0.060870 0.071479 0.002349 0.008247 0.031005 0.038015 0.002309 0.000030 0.047461 0.047973 0.002319 0.008220
Eisosomes 0.000114 0.000093 0.000040 0.000040 0.000035 0.000043 0.000024 0.004391 0.000078 0.000058 0.000028 0.000054
Endoplasmic Reticulum 0.001034 0.003942 0.008853 0.004087 0.001278 0.001831 0.002750 0.000006 0.001144 0.002459 0.004365 0.004074
Endosome 0.001268 0.005003 0.000909 0.003791 0.001342 0.003635 0.000683 0.000002 0.001301 0.004042 0.000743 0.003778
Golgi 0.000382 0.001596 0.000048 0.001887 0.000470 0.001438 0.000033 0.000031 0.000422 0.001485 0.000037 0.001881
Lipid Particles 0.007358 0.007472 0.001049 0.001534 0.003123 0.004522 0.000512 0.000487 0.005456 0.005400 0.000654 0.001530
Mitochondria 0.003126 0.011712 0.001245 0.001721 0.002270 0.008037 0.000660 0.000085 0.002742 0.009130 0.000815 0.001716
Mitotic Spindle 0.000109 0.006186 0.001254 0.015412 0.001967 0.012438 0.001896 0.000656 0.000943 0.010577 0.001726 0.015364
None 0.023779 0.010149 0.003454 0.011838 0.006125 0.007632 0.006879 0.987717* 0.015853 0.008381 0.005973 0.014970
Nuclear Periphery 0.000719 0.001850 0.001653 0.003328 0.001063 0.002199 0.001316 0.000001 0.000873 0.002096 0.001405 0.003317
Nuclear Periphery Foci 0.000260 0.001221 0.000349 0.000874 0.000368 0.000884 0.000181 0.000004 0.000308 0.000984 0.000225 0.000871
Nucleolus 0.003315 0.005143 0.001481 0.000878 0.001890 0.003565 0.000837 0.000007 0.002675 0.004034 0.001008 0.000875
Nucleus 0.542619* 0.627445* 0.910938* 0.643342* 0.758883* 0.690494* 0.859141* 0.000026 0.639716* 0.671732* 0.872846* 0.641278*
Peroxisomes 0.001976 0.015318 0.000208 0.000526 0.001495 0.004881 0.000104 0.003799 0.001760 0.007987 0.000132 0.000537
Vacuole 0.006767 0.026458 0.016690 0.041814 0.005327 0.012739 0.010574 0.000001 0.006120 0.016821 0.012193 0.041680
Vacuole Periphery 0.000416 0.000904 0.000255 0.001802 0.000551 0.001038 0.000146 0.000000 0.000476 0.000998 0.000175 0.001796

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.95 -8.46 -8.51 0.51 2.47 NaN NaN NaN NaN NaN -3.51 -10.45 -8.74 -0.71 -3.25
Bud Neck -3.85 2.28 -2.16 2.65 -4.43 NaN NaN NaN NaN NaN -5.63 -0.41 -5.30 0.24 -4.70
Bud Site 1.27 1.67 -0.48 -1.96 -2.20 NaN NaN NaN NaN NaN -0.88 2.16 -2.91 -2.30 -4.70
Cell Periphery 7.37 8.82 7.10 0.05 -2.82 NaN NaN NaN NaN NaN 6.23 8.37 4.95 -0.79 -2.99
Cytoplasm 16.20 42.69 19.95 0.76 -19.78 NaN NaN NaN NaN NaN 12.65 35.06 13.18 2.53 -14.28
Cytoplasmic Foci -2.51 24.42 22.62 15.29 -3.53 NaN NaN NaN NaN NaN -0.56 28.17 24.31 20.52 -4.07
Eisosomes 1.91 10.20 10.15 6.87 -1.12 NaN NaN NaN NaN NaN 4.52 12.62 1.07 -0.51 -2.81
Endoplasmic Reticulum -8.89 -11.19 -17.74 -5.40 4.92 NaN NaN NaN NaN NaN -7.26 -14.55 -17.20 -12.61 -2.09
Endosome -7.38 0.59 -2.30 4.65 -2.60 NaN NaN NaN NaN NaN -7.04 2.75 -2.15 3.67 -3.33
Golgi -2.68 5.20 -1.01 1.44 -1.91 NaN NaN NaN NaN NaN -3.11 3.67 -0.87 1.48 -1.95
Lipid Particles -0.13 8.03 7.68 8.29 -0.05 NaN NaN NaN NaN NaN 0.06 10.30 8.10 7.98 -1.63
Mitochondria -4.05 3.92 4.48 5.00 -0.02 NaN NaN NaN NaN NaN -6.24 5.27 3.67 7.98 -3.61
Mitotic Spindle -4.13 -1.97 -6.57 -2.75 -4.99 NaN NaN NaN NaN NaN -6.39 -1.92 -6.08 -1.31 -5.40
None 5.41 10.52 7.50 0.90 -5.07 NaN NaN NaN NaN NaN 5.63 8.57 2.44 -1.50 -3.38
Nuclear Periphery -6.96 -9.96 -6.49 -3.93 -3.74 NaN NaN NaN NaN NaN -6.36 -11.94 -6.17 -3.46 -4.22
Nuclear Periphery Foci -4.27 -3.04 -5.24 1.25 -3.02 NaN NaN NaN NaN NaN -3.29 -0.35 -4.84 0.21 -4.85
Nucleolus -2.06 3.62 4.86 6.27 4.42 NaN NaN NaN NaN NaN -2.79 5.34 5.70 8.85 1.29
Nucleus -5.99 -37.72 -14.09 -4.58 21.93 NaN NaN NaN NaN NaN -3.64 -35.51 -4.60 -1.36 22.73
Peroxisomes -6.29 7.74 7.23 7.11 -1.17 NaN NaN NaN NaN NaN -7.77 7.93 7.01 9.93 -2.35
Vacuole -9.13 -6.68 -18.78 -10.29 -11.36 NaN NaN NaN NaN NaN -11.49 -10.17 -18.96 -15.19 -14.75
Vacuole Periphery -3.49 1.92 -1.02 0.31 -1.50 NaN NaN NaN NaN NaN -2.68 3.18 -0.82 0.61 -1.79
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV
Localization
Cell Percentages nucleus (33%), cytoplasm (4%), mixed (54%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rad30

Rad30


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad30-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available